Organisation profile
Organisation Profile
Pregnancy and Genes - translational research in common obstetric disorders
Pre-eclampsia, fetal growth restriction and gestational diabetes mellitus are common disorders of pregnancy. The impact of these disorders is not limited to obstetric and pediatric domains. They are also associated with increased risk of morbidity in later life of both the mother and the child. We investigate susceptibility genes, molecular mechanisms, risk factors, and implications to later life.
Postdoctoral fellows:
Tiina Jääskeläinen PhD, Jenni Heikkinen-Eloranta MD, Pia Villa MD, PhD, Inkeri Lokki PhD, Miira Klemetti MD PhD
Graduate students:
Tea Kaartokallio MSc, Katja Murtoniemi MD, Sanna Suomalainen-König MD
Research nurse: Eija Kortelainen
Laboratory technician: Susanna Mehtälä
Fields of Science
- 311 Basic medicine
- molecular genetics
- 312 Clinical medicine
- pre-eclampsia
- gestational diabetes
Collaborations and top research areas from the last five years
Profiles
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Tiina Jääskeläinen
- Medicum - Visiting scholar
- Department of Food and Nutrition - University Lecturer
- Doctoral Programme in Population Health - Supervisor for doctoral programme
- Pregnancy and Genes
Person: Visiting scholar, U3 Research and teaching staff
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Eija Kortelainen
- Department of Medical and Clinical Genetics - Clinical Research Nurse
- Pregnancy and Genes
Person: M5 Teaching and research support staff
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Pre-eclampsia and future cardiovascular health: An underused opportunity to improve family health
Jääskeläinen, T. (Project manager)
01/01/2019 → …
Project: Research project
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Finngen: FinnGen
Palotie, A. (Project manager), Pitkänen, K. (Principal Investigator), Jalanko, A. (Principal Investigator), Lyhs, U. (Participant), Donner, K. M. (Participant), Kaunisto, M. (Participant), Kurki, M. I. (Participant), Kristiansson, K. (Participant), Laiho, P. (Participant), Laivuori, H. (Participant), Loukola, A. (Participant), Palta, P. (Participant), Perola, M. (Project manager), Kajanne, R. (Project manager), Harju, J. J. (Project manager) & Havulinna, A. (Project manager)
15/08/2017 → …
Project: Research project
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HLA-alueen geenien yhteys HELLP-oireyhtymään
Heikkinen-Eloranta, J. (Principal Investigator), Laivuori, H. (Participant), Lokki, A. I. (Participant) & Lokki, M.-L. (Participant)
31/10/2013 → …
Project: Research project
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Severe pre-eclampsia
Heikkinen-Eloranta, J. (Participant), Lokki, A. I. (Participant) & Laivuori, H. (Participant)
01/01/2014 → 31/01/2015
Project: Research project
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Impact of Preeclampsia Duration on Long-Term Cardiovascular Disease Risk
FINNPEC Core Investigator Group, FinnGen, Keitaanpää, N., Tyrmi, J. S., Toivonen, E., Kivelä, A., Heinonen, S., Jääskeläinen, T., Laivuori, H., Kere, J., Kivinen, K., Pouta, A., Palotie, A., Daly, M., Riley-Gills, B., Viollet, C., Berton, A., Tsai, E. A., Ding, Z. & Holzinger, E. & 83 others, , Feb 2026, In: Hypertension. 83, 2, 11 p., e25054.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Cardiometabolic health 8-12 years after pre-eclampsia: Role of obesity and gestational diabetes (FINNCARE study)
Kivelä, A., Renlund-Vikström, M., Heinonen, S., Sarkola, T., Laivuori, H. & Jääskeläinen, T., Sept 2025, In: Pregnancy Hypertension : an international journal of women's cardiovascular health. 41, 9 p., 101226.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
External causes are leading causes of death in women of reproductive age: a registry study on maternal perinatal health, hypertensive pregnancy disorders and mortality in Finland
Saarela, T., Peltomäki, L., Kivioja, A., Jääskeläinen, T., Haukka, J. & Laivuori, H., Sept 2025, In: Journal of Epidemiology and Community Health. 79, 9, p. 691-697 7 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Implementation of a web-based lifestyle intervention to promote cardiovascular health in families 8-12 years after pre-eclampsia (FINNCARE): a randomized, controlled trial
Kivelä, A., Aittasalo, M., Renlund-Vikström, M., Heinonen, S., Sarkola, T., Laivuori, H. & Jääskeläinen, T., Dec 2025, In: BMC digital health. 3, 1, 17 p., 87.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
Long-term cardiovascular risk in women with hypertensive disorders of pregnancy: Insights from polygenic risk scores
Kivioja, A., Tyrmi, J., Toivonen, E., Huhtala, H., FinnGen, Jääskeläinen, T., Kettunen, J., Saarela, T. & Laivuori, H., Oct 2025, In: Acta Obstetricia et Gynecologica Scandinavica. 104, 10, p. 1907-1917 11 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
Activities
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The International Society for the Study of Hypertension in Pregnancy (ISSHP) World Congress 2025
Jääskeläinen, T. (Speaker)
21 Sept 2025 → 24 Sept 2025Activity: Talk or presentation types › Oral presentation
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Society for Reproductive Investigation (SRI) meeting
Jääskeläinen, T. (Attendee)
25 Mar 2025 → 29 Mar 2025Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Society for Reproductive Investigation (SRI) annual meeting
Jääskeläinen, T. (Attendee)
12 Mar 2024 → 16 Mar 2024Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Lääkäripäivät 2023
Jääskeläinen, T. (Speaker)
26 Jan 2023Activity: Talk or presentation types › Oral presentation
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Nordic obesity meeting
Jääskeläinen, T. (Attendee)
17 Nov 2022 → 19 Nov 2022Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Prizes
Press/Media
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Tiedekulma: Hyvä paha ruoka – asiantuntijat purkavat ravitsemusmyyttejä
24/04/2024
1 item of Media coverage
Press/Media: Press / Media
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Tiedekulma / Mitä geenit kertovat terveydestä
11/04/2024
1 item of Media coverage
Press/Media: Press / Media
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-UNIVERSITY OF HELSINKI: Genetic study shows that the risk of preeclampsia is related to blood pressure and body mass index
26/11/2020
1 item of Media coverage
Press/Media: Press / Media
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Preeclampsia risk linked to blood pressure, BMI
26/11/2020
1 item of Media coverage
Press/Media: Press / Media
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Preeclampsia risk linked to blood pressure, body mass index
26/11/2020
1 item of Media coverage
Press/Media: Press / Media