• Haartmaninkatu 8, Biomedicum, B309b

    00014 Helsinki

    Finland

Publications 1996 2019

2019

Asiakasosallisuuden toteutuminen ja digitalisaation mahdollisuudet vammaissosiaalityön asiakasprosessissa

Kivistö, M., Heini, A., Kontu, K., Kunttu, K., Lappalainen, T., Lindroos, N., Ronimus, H. & Sjöblom, S., 2019, In : Kuntoutus. 42, 1, p. 18-24 7 p.

Research output: Contribution to journalArticleScientific

Impact of obesity on angiogenic and inflammatory markers in the Finnish Genetics of Pre-eclampsia Consortium (FINNPEC) cohort

the FINNPEC, May 2019, In : International Journal of Obesity. 43, 5, p. 1070-1081 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Psychiat Genomics Consortium, Czamara, D., Eraslan, G., Page, C. M., Lahti, J., Lahti-Pulkkinen, M., Hämäläinen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., Nystad, W., Håberg, S. E., London, S. J., O'Donnell, K. J., Garg, E., Meaney, M. J., Entringer, S., Wadhwa, P. D. & Buss, C., 11 Jun 2019, In : Nature Communications. 10, 18 p., 2548.

Research output: Contribution to journalArticleScientificpeer-review

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Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

Kupers, L. K., Monnereau, C., Sharp, G. C., Yousefi, P., Salas, L. A., Ghantous, A., Page, C. M., Reese, S. E., Wilcox, A. J., Czamara, D., Starling, A. P., Novoloaca, A., Lent, S., Roy, R., Hoyo, C., Breton, C., Allard, C., Just, A. C., Bakulski, K. M., Holloway, J. W. & 107 othersEverson, T. M., Xu, C-J., Huang, R-C., van der Plaat, D. A., Wielscher, M., Merid, S. K., Ullemar, V., Rezwan, F., Lahti, J., van Dongen, J., Langie, S. A. S., Richardson, T. G., Magnus, M. C., Nohr, E. A., Xu, Z., Duijts, L., Zhao, S., Zhang, W., Plusquin, M., DeMeo, D. L., Solomon, O., Heimovaara, J. H., Jima, D. D., Gao, L., Bustamante, M., Perron, P., Wright, R. O., Hertz-Picciotto, I., Zhang, H., Karagas, M. R., Gehring, U., Marsit, C. J., Beilin, L. J., Vonk, J. M., Jarvelin, M-R., Bergstrom, A., Ortqvist, A. K., Ewart, S., Villa, P. M., Moore, S. E., Willemsen, G., Standaert, A. R. L., Haberg, S. E., Sorensen, T. I. A., Taylor, J. A., Räikkönen, K., Yang, I., Kechris, K., Nawrot, T. S., Silver, M. J., Gong, Y. Y., Richiardi, L., Kogevinas, M., Litonjua, A. A., Eskenazi, B., Huen, K., Mbarek, H., Maguire, R. L., Dwyer, T., Vrijheid, M., Bouchard, L., Baccarelli, A. A., Croen, L. A., Karmaus, W., Anderson, D., de Vries, M., Sebert, S., Kere, J., Karlsson, R., Arshad, S. H., Hämäläinen, E., Routledge, M. N., Boomsma, D., Feinberg, A. P., Newschaffer, C. J., Govarts, E., Moisse, M., Fallin, M. D., Melen, E., Prentice, A. M., Kajantie, E., Almqvist, C., Oken, E., Dabelea, D., Boezen, H. M., Melton, P. E., Wright, R. J., Koppelman, G. H., Trevisi, L., Hivert, M-F., Sunyer, J., Munthe-Kaas, M. C., Murphy, S. K., Corpeleijn, E., Wiemels, J., Holland, N., Herceg, Z., Binder, E. B., Smith, G. D., Jaddoe, V. W. V., Lie, R. T., Nystad, W., London, S. J., Lawlor, D. A., Relton, C. L., Snieder, H. & Felix, J. F., 23 Apr 2019, In : Nature Communications. 10, 11 p., 1893.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Plasma Heme Scavengers Alpha-l-Microglobulin and Hemopexin as Biomarkers in High-Risk Pregnancies

Kalapotharakos, G., Murtoniemi, K., Åkerström, B., Hämäläinen, E., Kajantie, E., Räikkönen, K., Villa, P., Laivuori, H. & Hansson, S. R., 4 Apr 2019, In : Frontiers in Physiology. 10, 7 p., 300.

Research output: Contribution to journalArticleScientificpeer-review

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Pregnancy-associated stroke -a systematic review of subsequent pregnancies and maternal health

Karjalainen, L., Tikkanen, M., Rantanen, K., Laivuori, H., Gissler, M. & Ijäs, P., 28 May 2019, In : BMC Pregnancy and Childbirth. 19, 10 p., 187.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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Temporal and external validation of the fullPIERS model for the prediction of adverse maternal outcomes in women with pre-eclampsia

FullPIERS Grp, Ukah, U. V., Payne, B., Karjalainen, H., Kortelainen, E., Seed, P. T., Conti-Ramsden, F. I., Cao, V., Laivuori, H., Hutcheon, J., Chappell, L., Ansermino, J. M., Vatish, M., Redman, C., Lee, T., Li, L., Magee, L. A. & von Dadelszen, P., Jan 2019, In : Pregnancy Hypertension : an international journal of women's cardiovascular health. 15, p. 42-50 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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The health of children conceived by ART: "the chicken or the egg?'

Berntsen, S., Söderström-Anttila, V., Wennerholm, U-B., Laivuori, H., Loft, A., Oldereid, N. B., Romundstad, L. B., Bergh, C. & Pinborg, A., 2019, In : Human Reproduction Update. 25, 2, p. 137-158 22 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

2018

Angiogenic Profile in the Finnish Genetics of Pre-Eclampsia Consortium (Finnpec) Cohort

Jääskeläinen, T., Heinonen, S., Hämäläinen, E., Pulkki, K., Romppanen, J. & Laivuori, H., Oct 2018, In : Pregnancy Hypertension : an international journal of women's cardiovascular health. 14, p. 252-259 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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A Non-Targeted LC-MS Profiling Reveals Elevated Levels of Carnitine Precursors and Trimethylated Compounds in the Cord Plasma of Pre-Eclamptic Infants

FINNPEC, 2 Oct 2018, In : Scientific Reports. 8, 12 p., 14616.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Fetal Microsatellite in the Heme Oxygenase 1 Promoter Is Associated With Severe and Early-Onset Preeclampsia

Kaartokallio, T., Utge, S., Klemetti, M. M., Paananen, J., Pulkki, K., Romppanen, J., Tikkanen, I., Heinonen, S., Kajantie, E., Kere, J., Kivinen, K., Pouta, A., Lakkisto, P. & Laivuori, H., Jan 2018, In : Hypertension. 71, 1, p. 95-102 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Geneettisen analytiikan mahdollisuudet sikiödiagnostiikassa

Salminen, E., Saloranta, C. & Laivuori, H., 2018, In : Duodecim. 134, 4, p. 383-390 8 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

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Identification of OAF and PVRL1 as candidate genes for an ocular anomaly characterized by Peters anomaly type 2 and ectopia lentis

David, D., Anand, D., Araujo, C., Gloss, B., Fino, J., Dinger, M., Lindahl, P., Pöyhönen, M., Laivuori, H. & Lavinha, J., Mar 2018, In : Experimental Eye Research. 168, p. 161-170 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Kestävän kehityksen lääketiede: yhdenvertaisuutta tutkitun tiedon keinoin

Klemetti, M., Sainio, S., Salmi, H. & Tiittala, P., 2018, In : Suomen lääkärilehti. 73, 38, p. 2057 1 p.

Research output: Contribution to journalEditorialProfessional

Maternal early pregnancy obesity and depressive symptoms during and after pregnancy.

Kumpulainen, S. M., Girchenko, P., Lahti-Pulkkinen, M., Reynolds, R. M., Tuovinen, S., Pesonen, A-K., Heinonen, K., Kajantie, E., Villa, P. M., Hämäläinen, E., Laivuori, H. & Räikkönen, K., Oct 2018, In : Psychological Medicine. 48, 14, p. 2353-2363 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Placental Morphology Is Associated with Maternal Depressive Symptoms during Pregnancy and Toddler Psychiatric Problems.

Lahti-Pulkkinen, M., Cudmore, M., Haeussner, E., Schmitz, C., Pesonen, A-K., Hämäläinen, E., Villa, P. M., Mehtälä, S., Kajantie, E., Laivuori, H., Reynolds, R. M., Frank, H-G. & Räikkönen, K., 15 Jan 2018, In : Scientific Reports. 8, 1, 12 p., 791.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Polycystic ovary syndrome and risk factors for gestational diabetes

Mustaniemi, S., Vääräsmäki, M., Eriksson, J. G., Gissler, M., Laivuori, H., Ijäs, H., Bloigu, A., Kajantie, E. & Morin-Papunen, L., 1 Jul 2018, In : Endocrine Connections. 7, 7, p. 859-869 11 p.

Research output: Contribution to journalArticleScientificpeer-review

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Prediction of pre-eclampsia and its subtypes in high-risk cohort: hyperglycosylated human chorionic gonadotropin in multivariate models

Murtoniemi, K., Villa, P. M., Matomäki, J., Keikkala, E., Vuorela, P., Hämäläinen, E., Kajantie, E., Pesonen, A-K., Räikkönen, K., Taipale, P., Stenman, U-H. & Laivuori, H., 3 Jul 2018, In : BMC Pregnancy and Childbirth. 18, 10 p., 279.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Robust increases in erythropoietin production by the hypoxic fetus is a response to protect the brain and other vital organs

Teramo, K. A., Klemetti, M. M. & Widness, J. A., Dec 2018, In : Pediatric Research. 84, 6, p. 807-812 6 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

The Effect of Low-Dose Aspirin On Serum Placental Growth Factor Levels In a High-Risk PREDO Cohort

Murtoniemi, K., Vahlberg, T., Hämäläinen, E., Kajantie, E., Pesonen, A. K., Räikkönen, K., Taipale, P., Villa, P. M. & Laivuori, H., Jul 2018, In : Pregnancy Hypertension : an international journal of women's cardiovascular health. 13, p. 51-57 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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The effect of paternal factors on perinatal and paediatric outcomes: a systematic review and meta-analysis

Oldereid, N. B., Wennerholm, U-B., Pinborg, A., Loft, A., Laivuori, H., Petzold, M., Romundstad, L. B., Soderstrom-Anttila, V. & Bergh, C., 2018, In : Human Reproduction Update. 24, 3, p. 320-389 70 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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The Epigenetic Clock at Birth: Associations With Maternal Antenatal Depression and Child Psychiatric Problems

Suarez, A., Lahti, J., Czamara, D., Lahti-Pulkkinen, M., Knight, A. K., Girchenko, P., Hämäläinen, E., Kajantie, E., Lipsanen, J., Laivuori, H., Villa, P. M., Reynolds, R. M., Smith, A. K., Binder, E. B. & Räikkönen, K., May 2018, In : Journal of the American Academy of Child and Adolescent Psychiatry. 57, 5, p. 321-+ 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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The Immunogenetic Conundrum of Preeclampsia

Lokki, A. I., Heikkinen-Eloranta, J. K. & Laivuori, H., 13 Nov 2018, In : Frontiers in Immunology. 9, 8 p., 2630.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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Tyypin 1 diabeetikon  raskauden erityispiirteet

Klemetti, M., Gordin, D., Tikkanen, M., Nuutila, M. & Teramo, K., 2018, In : Suomen lääkärilehti. 73, 21, p. 1351-1356 6 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

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2017

Analysis of Complement C3 Gene Reveals Susceptibility to Severe Preeclampsia

Lokki, A. I., Kaartokallio, T., Holmberg, V., Onkamo, P., Koskinen, L. L. E., Saavalainen, P., Heinonen, S., Kajantie, E., Kere, J., Kivinen, K., Pouta, A., Villa, P. M., Hiltunen, L., Laivuori, H. & Meri, S., 29 May 2017, In : Frontiers in Immunology. 8, 10 p., 589.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Angiogenic profile and smoking in the Finnish Genetics of Pre-Eclampsia Consortium (FINNPEC) cohort

FINNPEC, 2017, In : Annals of Medicine. 49, 7, p. 593–602 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Associations between maternal risk factors of adverse pregnancy and birth outcomes and the offspring epigenetic clock of gestational age at birth

Girchenko, P., Lahti, J., Czamara, D., Knight, A. K., Jones, M. J., Suarez Figueiredo, A., Hämäläinen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., Kobor, M. S., Smith, A. K., Binder, E. B. & Räikkönen, K., 8 May 2017, In : Clinical epigenetics. 9, 14 p., 49.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Cluster analysis to estimate the risk of preeclampsia in the high-risk Prediction and Prevention of Preeclampsia and Intrauterine Growth Restriction (PREDO) study

Villa, P. M., Marttinen, P., Gillberg, J., Lokki, A. I., Majander, K., Ordén, M-R., Taipale, P., Pesonen, A., Räikkönen, K., Hämäläinen, E., Kajantie, E. & Laivuori, H., 28 Mar 2017, In : PLoS One. 12, 3, 14 p., 0174399.

Research output: Contribution to journalArticleScientificpeer-review

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Cohort Profile: Prediction and prevention of preeclampsia and intrauterine growth restriction (PREDO) study

Girchenko, P., Lahti, M., Tuovinen, S., Savolainen, K., Lahti, J., Binder, E. B., Reynolds, R. M., Entringer, S., Buss, C., Wadhwa, P. D., Hamalainen, E., Kajantie, E., Pesonen, A-K., Villa, P. M., Laivuori, H. & Raikkonen, K., Oct 2017, In : International Journal of Epidemiology. 46, 5, p. 1380-+ 9 p.

Research output: Contribution to journalEditorialScientificpeer-review

Open Access

Epigenetic clock at birth and psychiatric problems during early childhood

Suarez, A., Lahti, J., Czamara, D., Lahti, M., Knight, A. K., Girchenko, P., Hämäläinen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., Smith, A. K., Binder, E. B. & Räikkönen, K., Sep 2017, In : Psychoneuroendocrinology. 83S, p. 52-52 1 p.

Research output: Contribution to journalMeeting AbstractResearch

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Fetal sex-specific differences in gestational age at delivery in pre-eclampsia: a meta-analysis

Schalekamp-Timmermans, S., Arends, L. R., Alsaker, E., Chappell, L., Hansson, S., Harsem, N. K., Jalmby, M., Jeyabalan, A., Laivuori, H., Lawlor, D. A., Macdonald-Wallis, C., Magnus, P., Myers, J., Olsen, J., Poston, L., Redman, C. W., Staff, A. C., Villa, P., Roberts, J. M., Steegers, E. A. & 1 othersGlobal Pregnancy Collaboration, Apr 2017, In : International Journal of Epidemiology. 46, 2, p. 632-642 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Prediction and prevention of pre-eclampsia

Villa, P. M., 2017, Helsinki: [P. M. Villa] . 107 p.

Research output: ThesisDoctoral ThesisCollection of Articles

Protective Low-Frequency Variants for Preeclampsia in the Fms Related Tyrosine Kinase 1 Gene in the Finnish Population

Lokki, A. I., Daly, E., Triebwasser, M., Kurki, M. I., Roberson, E. D. O., Happola, P., Auro, K., Perola, M., Heinonen, S., Kajantie, E., Kere, J., Kivinen, K., Pouta, A., Salmon, J. E., Meri, S., Daly, M., Atkinson, J. P. & Laivuori, H., Aug 2017, In : Hypertension. 70, 2, p. 365-+ 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

SIRT6 polymorphism rs117385980 is associated with longevity and healthy aging in Finnish men

Hirvonen, K., Laivuori, H., Lahti, J., Strandberg, T., Eriksson, J. G. & Hackman, P., 11 Apr 2017, In : BMC Medical Genetics. 18, 5 p., 41.

Research output: Contribution to journalArticleScientificpeer-review

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The conundrum of pre-eclampsia – from candidate genes to complement system

Lokki, A. I., 24 Nov 2017, Helsinki: [A. I. Lokki]. 175 p.

Research output: ThesisDoctoral ThesisCollection of Articles

Variants in the fetal genome near FLT1 are associated with risk of preeclampsia

McGinnis, R., Steinthorsdottir, V., Williams, N. O., Thorleifsson, G., Shooter, S., Hjartardottir, S., Bumpstead, S., Stefansdottir, L., Hildyard, L., Sigurdsson, J. K., Kemp, J. P., Silva, G. B., Thomsen, L. C. V., Jaaskelainen, T., Kajantie, E., Chappell, S., Kalsheker, N., Moffett, A., Hiby, S., Lee, W. K. & 28 othersPadmanabhan, S., Simpson, N. A. B., Dolby, V. A., Staines-Urias, E., Engel, S. M., Haugan, A., Trogstad, L., Svyatova, G., Zakhidova, N., Najmutdinova, D., Dominiczak, A. F., Gjessing, H. K., Casas, J. P., Dudbridge, F., Walker, J. J., Pipkin, F. B., Thorsteinsdottir, U., Geirsson, R. T., Lawlor, D. A., Iversen, A-C., Magnus, P., Laivuori, H., Stefansson, K., Morgan, L., FINNPEC Consortium, Heinonen, S., Kere, J. & GOPEC Consortium, Aug 2017, In : Nature Genetics. 49, 8, p. 1255-+ 9 p.

Research output: Contribution to journalArticleScientificpeer-review

2016

An epigenetic clock for gestational age at birth based on blood methylation data

Knight, A. K., Craig, J. M., Theda, C., Baekvad-Hansen, M., Bybjerg-Grauholm, J., Hansen, C. S., Hollegaard, M. V., Hougaard, D. M., Mortensen, P. B., Weinsheimer, S. M., Werge, T. M., Brennan, P. A., Cubells, J. F., Newport, D. J., Stowe, Z. N., Cheong, J. L. Y., Dalach, P., Doyle, L. W., Loke, Y. J., Baccarelli, A. A. & 26 othersJust, A. C., Wright, R. O., Tellez-Rojo, M. M., Svensson, K., Trevisi, L., Kennedy, E. M., Binder, E. B., Iurato, S., Räikkönen, K., Lahti, J. M. T., Pesonen, A-K., Kajantie, E., Villa, P. M., Laivuori, H., Hämäläinen, E., Park, H. J., Bailey, L. B., Parets, S. E., Kilaru, V., Menon, R., Horvath, S., Bush, N. R., LeWinn, K. Z., Tylavsky, F. A., Conneely, K. N. & Smith, A. K., 7 Oct 2016, In : Genome Biology. 17, 11 p., 206.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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An RGS2 3 ' UTR polymorphism is associated with preeclampsia in overweight women

Karppanen, T., Kaartokallio, T., Klemetti, M. M., Heinonen, S., Kajantie, E., Kere, J., Kivinen, K., Pouta, A., Staff, A. C. & Laivuori, H., 24 Aug 2016, In : BMC Genetics. 17, 7 p., 121.

Research output: Contribution to journalArticleScientificpeer-review

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Cohort profile: the Finnish Genetics of Pre-eclampsia Consortium (FINNPEC)

FINNPEC Study Grp, 10 Nov 2016, In : BMJ Open. 6, 11, 8 p., 013148.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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