• Haartmaninkatu 8, Biomedicum, B309b

    00014 Helsinki

    Finland

Publications 1996 2019

2016

Exome sequencing in pooled DNA samples to identify maternal pre-eclampsia risk variants

Kaartokallio, T., Wang, J., Heinonen, S. T., Kajantie, E., Kivinen, K., Pouta, A., Gerdhem, P., Jiao, H., Kere, J. & Laivuori, H., 7 Jul 2016, In : Scientific Reports. 6, 9 p., 29085.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Extending the scope of pooled analyses of individual patient biomarker data from heterogeneous laboratory platforms and cohorts using merging algorithms

Burke, O., Benton, S., Szafranski, P., von Dadelszen, P., Buhimschi, S. C., Cetin, I., Chappell, L., Figueras, F., Galindo, A., Herraiz, I., Holzman, C., Hubel, C., Knudsen, U., Kronborg, C., Laivuori, H., Lapaire, O., McElrath, T., Moertl, M., Myers, J., Ness, R. B. & 18 othersOliveira, L., Olson, G., Poston, L., Ris-Stalpers, C., Roberts, J. M., Schalekamp-Timmermans, S., Schlembach, D., Steegers, E., Stepan, H., Tsatsaris, V., van der Post, J. A., Verlohren, S., Villa, P. M., Williams, D., Zeisler, H., Redman, C. W. G., Staff, A. C. & Global Pregnancy Collaboration, Jan 2016, In : Pregnancy Hypertension : an international journal of women's cardiovascular health. 6, 1, p. 53-59 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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First trimester serum placental growth factor and hyperglycosylated human chorionic gonadotropin are associated with pre-eclampsia: a case control study

Keikkala, E., Koskinen, S., Vuorela, P., Laivuori, H., Romppanen, J., Heinonen, S. & Stenman, U-H., 25 Nov 2016, In : BMC Pregnancy and Childbirth. 16, 10 p., 378.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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FTO genotype and weight loss: systematic review and meta-analysis of 9563 individual participant data from eight randomised controlled trials

Livingstone, K. M., Celis-Morales, C., Papandonatos, G. D., Erar, B., Florez, J. C., Jablonski, K. A., Razquin, C., Marti, A., Heianza, Y., Huang, T., Sacks, F. M., Svendstrup, M., Sui, X., Church, T. S., Jääskeläinen, T., Lindstrom, J., Tuomilehto, J., Uusitupa, M., Rankinen, T., Saris, W. H. M. & 12 othersHansen, T., Pedersen, O., Astrup, A., Sorensen, T. I. A., Qi, L., Bray, G. A., Martinez-Gonzalez, M. A., Martinez, J. A., Franks, P. W., McCaffery, J. M., Lara, J. & Mathers, J. C., 20 Sep 2016, In : BMJ : British Medical Journal. 354, 11 p., 4707.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Interaction between rs10830963 polymorphism in MTNR1B and lifestyle intervention on occurrence of gestational diabetes

Grotenfelt, N. E., Wasenius, N. S., Rönö, K., Laivuori, H., Stach-Lempinen, B., Orho-Melander, M., Schulz, C-A., Kautiainen, H., Koivusalo, S. B. & Eriksson, J. G., 1 Aug 2016, In : Diabetologia. 59, 8, p. 1655-1658 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Investigation of rare and low-frequency variants using high-throughput sequencing with pooled DNA samples

Wang, J., Skoog, T., Einarsdottir, E., Kaartokallio, T., Laivuori, H., Grauers, A., Gerdhem, P., Hytonen, M., Lohi, H., Kere, J. & Jiao, H., 16 Sep 2016, In : Scientific Reports. 6, 11 p., 33256.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Maternal depression during pregnancy and epigenetic age in their newborns: The PREDO study

Suarez Figueiredo, A., Lahti, J. M. T., Girchenko, P., Lahti, M., Hämäläinen, E., Laivuori, H. M., Kajantie, E. O., Pesonen, A-K., Villa, P. M., Reynolds, R., Czamara, D., Smith, A. K., Binder, E. B. & Räikkönen, K., Sep 2016, In : Psychoneuroendocrinology. 71S, 1 p.

Research output: Contribution to journalConference articleScientificpeer-review

Maternal Prenatal Positive Affect, Depressive and Anxiety Symptoms and Birth Outcomes: The PREDO Study

Pesonen, A-K., Lahti, M., Kuusinen, T., Tuovinen, S., Villa, P., Hämäläinen, E., Laivuori, H., Kajantie, E. & Räikkönen, K., 26 Feb 2016, In : PLoS One. 11, 2, 13 p., 0150058.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Stanniocalcin-1 Hormone in Nonpreeclamptic and Preeclamptic Pregnancy: Clinical, Life-Style, and Genetic Modulators

Juhanson, P., Rull, K., Kikas, T., Laivuori, H., Vaas, P., Kajantie, E., Heinonen, S. & Laan, M., Dec 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 12, p. 4799-4807 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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The diagnosis of pre-eclampsia using two revised classifications in the Finnish Pre-eclampsia Consortium (FINNPEC) cohort

Kallela, J., Jääskeläinen, T., Kortelainen, E., Heinonen, S., Kajantie, E., Kere, J., Kivinen, K., Pouta, A. & Laivuori, H., 12 Aug 2016, In : BMC Pregnancy and Childbirth. 16, 7 p., 221.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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The Salivary Scavenger and Agglutinin (SALSA) in Healthy and Complicated Pregnancy

Reichhardt, M. P., Jarva, H., Lokki, A. I., Laivuori, H., Vuorela, P., Loimaranta, V., Glasner, A., Siwetz, M., Huppertz, B., Meri, S. & FINNPEC Study Grp, 1 Feb 2016, In : PLoS One. 11, 2, 19 p., 0147867.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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White's classification and pregnancy outcome in women with type 1 diabetes: a population-based cohort study

Klemetti, M. M., Laivuori, H., Tikkanen, M., Nuutila, M., Hiilesmaa, V. & Teramo, K., Jan 2016, In : Diabetologia. 59, 1, p. 92-100 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
2015

Candidate gene analysis and exome sequencing confirm LBX1 as a susceptibility gene for idiopathic scoliosis

Grauers, A., Wang, J., Einarsdottir, E., Simony, A., Danielsson, A., Akesson, K., Ohlin, A., Halldin, K., Grabowski, P., Tenne, M., Laivuori, H., Dahlman, I., Andersen, M., Christensen, S. B., Karlsson, M. K., Jiao, H., Kere, J. & Gerdhem, P., 1 Oct 2015, In : The spine journal : official journal of the North American Spine Society. 15, 10, p. 2239-2246 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Gene expression profiling of pre-eclamptic placentae by RNA sequencing

Kaartokallio, T., Cervera, A., Kyllonen, A., Laivuori, K., Kere, J., Laivuori, H. & FINNPEC Core Invest Grp, 21 Sep 2015, In : Scientific Reports. 5, 15 p., 14107.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Genetic Analysis of Membrane Cofactor Protein (CD46) of the Complement System in Women with and without Preeclamptic Pregnancies

Lokki, A. I., Aalto-Viljakainen, T., Meri, S., Laivuori, H., FINNPEC & Kere, J. K., 24 Feb 2015, In : PLoS One. 10, 2, 10 p., 0117840.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Genome-wide blood DNA methylation alterations at regulatory elements and heterochromatic regions in monozygotic twins discordant for obesity and liver fat

Ollikainen, M., Ismail, K., Gervin, K., Kyllonen, A., Hakkarainen, A., Lundbom, J., Jarvinen, E. A., Harris, J. R., Lundbom, N., Rissanen, A., Lyle, R., Pietilainen, K. H. & Kaprio, J., 2 Apr 2015, In : Clinical epigenetics. 7, 13 p., 39.

Research output: Contribution to journalArticleScientificpeer-review

Maternal depressive symptoms during pregnancy, placental expression of genes regulating glucocorticoid and serotonin function and infant regulatory behaviors

Raikkonen, K., Pesonen, A. -K., O'Reilly, J. R., Tuovinen, S., Lahti, M., Kajantie, E., Villa, P., Laivuori, H., Hamalainen, E., Seckl, J. R. & Reynolds, R. M., Nov 2015, In : Psychological Medicine. 45, 15, p. 3217-3226 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Maternal depressive symptoms throughout pregnancy are associated with increased placental glucocorticoid sensitivity

Reynolds, R. M., Pesonen, A. -K., O'Reilly, J. R., Tuovinen, S., Lahti, M., Kajantie, E., Villa, P. M., Laivuori, H., Hämäläinen, E., Seckl, J. R. & Raikkonen, K., Jul 2015, In : Psychological Medicine. 45, 10, p. 2023-2030 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Meta-Analysis of Placental Transcriptome Data Identifies a Novel Molecular Pathway Related to Preeclampsia

van Uitert, M., Moerland, P. D., Enquobahrie, D. A., Laivuori, H., van der Post, J. A. M., Ris-Stalpers, C. & Afink, G. B., 14 Jul 2015, In : PLoS One. 10, 7, 15 p., 0132468.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Pre-eklampsia - monimuotoinen tautikirjo

Murtoniemi, K., Villa, P. M. & Laivuori, H., 2015, In : Kliin lab : kliinisen laboratorioalan julkaisu : SKKY:n jäsenlehti.. 32, 1, p. 7-9 3 p.

Research output: Contribution to journalArticleProfessional

2014

Asetyylisalisyylihappo ja pre-eklampsian ehkäisy

Villa, P. M., Kajantie, E. & Laivuori, H., 2014, In : Duodecim. 130, 3, p. 243-250 8 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Associations between maternal level of education and occupational status with placental glucocorticoid regeneration and sensitivity

Raikkonen, K., O'Reilly, J. R., Pesonen, A-K., Kajantie, E., Villa, P., Laivuori, H., Hamalainen, E., Seckl, J. R. & Reynolds, R. M., Aug 2014, In : Clinical Endocrinology. 81, 2, p. 175-182 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Evaluation of the RHINO gene for breast cancer predisposition in Finnish breast cancer families

Heikkinen, T., Khan, S., Huovari, E., Vilske, S., Schleutker, J., Kallioniemi, A., Blomqvist, C., Aittomaki, K. & Nevanlinna, H., Apr 2014, In : Breast Cancer Research and Treatment. 144, 2, p. 437-441 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Hypertension after preeclampsia and relation to the C1114G polymorphism (rs4606) in RGS2: data from the Norwegian HUNT2 study

Kvehaugen, A. S., Melien, O., Holmen, O. L., Laivuori, H., Dechend, R. & Staff, A. C., 5 Mar 2014, In : BMC Medical Genetics. 15, 10 p., 28.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Microsatellite Polymorphism in the Heme Oxygenase-1 Gene Promoter Is Associated with Non-Severe and Late-Onset Pre-Eclampsia

Klemetti, M. M., Kaartokallio, T., Lakkisto, P. & Laivuori, H., Mar 2014, In : Reproductive Sciences. 21, 3, p. 300A-300A 1 p.

Research output: Contribution to journalArticleScientificpeer-review

Microsatellite Polymorphism in the Heme Oxygenase-1 Promoter Is Associated With Nonsevere and Late-Onset Preeclampsia

Kaartokallio, T., Klemetti, M. M., Timonen, A., Uotila, J., Heinonen, S., Kajantie, E., Kere, J., Kivinen, K., Pouta, A., Lakkisto, P. & Laivuori, H., Jul 2014, In : Hypertension. 64, 1, p. 172-177 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Serum hyperglycosylated human chorionic gonadotrophin at 14-17 weeks of gestation does not predict preeclampsia

Keikkala, E., Ranta, J. K., Vuorela, P., Leinonen, R., Laivuori, H., Vaisanen, S., Marttala, J., Romppanen, J., Pulkki, K., Stenman, U-H. & Heinonen, S., 1 Jul 2014, In : Prenatal Diagnosis. 34, 7, SI, p. 699-705 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Strategy for Standardization of Preeclampsia Research Study Design

Myatt, L., Redman, C. W., Staff, A. C., Hansson, S., Wilson, M. L., Laivuori, H., Poston, L., Roberts, J. M. & Global Pregnancy CoLab COLAB, Jun 2014, In : Hypertension. 63, 6, p. 1293-1301 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Aspirin in the prevention of pre-eclampsia in high-risk women

Villa, P. M., Kajantie, E., Räikkönen, K., Pesonen, A-K., Hämäläinen, E., Vainio, M., Taipale, P. & Laivuori, H., May 2013, In : BJOG : An International Journal of Obstetrics & Gynaecology. 120, 6, p. 773-773 1 p.

Research output: Contribution to journalArticleScientific

High degree of cryptic population differentiation in the Baltic Sea herring Clupea harengus

Corander, J., Majander, K. K., Cheng, L. & Merila, J., Jun 2013, In : Molecular Ecology. 22, 11, p. 2931-2940 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Pre-eklampsia ja kromosomin 19 mikroRNA-klusteri

Kyllönen, A., 22 Jan 2013, Helsinki: [A. Kyllönen].

Research output: ThesisMaster's thesisTheses

Pre-eklampsia on monimuotoinen tautikirjo

Villa, P. & Laivuori, H., 2013, In : Suomen lääkärilehti. 68, 43, p. 2731 1 p.

Research output: Contribution to journalArticleProfessional

Prevention of perinatal death and adverse perinatal outcome using low-dose aspirin: a meta-analysis

Roberge, S., Nicolaides, K. H., Demers, S., Villa, P. & Bujold, E., May 2013, In : Ultrasound in Obstetrics & Gynecology. 41, 5, p. 491-499 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Vasoactive agents for the prediction of early- and late-onset preeclampsia in a high-risk cohort

Villa, P. M., Hämäläinen, E., Maki, A., Räikkönen, K., Pesonen, A-K., Taipale, P., Kajantie, E. & Laivuori, H., 12 May 2013, In : BMC Pregnancy and Childbirth. 13, 10 p., 110.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2012

Cytochrome P450 Subfamily 2J Polypeptide 2 Expression and Circulating Epoxyeicosatrienoic Metabolites in Preeclampsia

Herse, F., LaMarca, B., Hubel, C. A., Kaartokallio, T., Lokki, A. I., Ekholm, E., Laivuori, H., Gauster, M., Huppertz, B., Sugulle, M., Ryan, M. J., Novotny, S., Brewer, J., Park, J-K., Kacik, M., Hoyer, J., Verlohren, S., Wallukat, G., Rothe, M., Luft, F. C. & 4 othersMuller, D. N., Schunck, W-H., Staff, A. C. & Dechend, R., 18 Dec 2012, In : Circulation . 126, 25, p. 2990-2999 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Early Administration of Low-Dose Aspirin for the Prevention of Preterm and Term Preeclampsia: A Systematic Review and Meta-Analysis

Roberge, S., Villa, P., Nicolaides, K., Giguere, Y., Vainio, M., Bakthi, A., Ebrashy, A. & Bujold, E., 2012, In : Fetal Diagnosis and Therapy. 31, 3, p. 141-146 6 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Early Administration of Low-Dose Aspirin for the Prevention of Severe and Mild Preeclampsia: A Systematic Review and Meta-Analysis

Roberge, S., Giguere, Y., Villa, P., Nicolaides, K., Vainio, M., Forest, J-C., von Dadelzen, P., Vaiman, D., Tapp, S. & Bujold, E., 2012, In : American Journal of Perinatology. 29, 7, p. 551-556 6 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

2011

An obesity-related FTO variant and the risk of pre-eclampsia in a Finnish study population

Klemetti, M., Hiltunen, L. M., Heino, S., Heinonen, S. T., Kajantie, E. & Laivuori, H., 3 Nov 2011, In : Journal of Pregnancy. 2011, 251470.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Association of the rs1424954 polymorphism of the ACVR2A gene with the risk of pre-eclampsia is not replicated in a Finnish study population

Lokki, I., Klemetti, M., Heino, S., Hiltunen, L., Heinonen, S. & Laivuori, H. M., 19 Dec 2011, In : BMC research notes. 4, 6 p., 545.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Lactase persistence genotypes and malaria susceptibility in Fulani of Mali

Lokki, A. I., Jarvela, I., Israelsson, E., Maiga, B., Troye-Blomberg, M., Dolo, A., Doumbo, O. K., Meri, S. & Holmberg, V., 14 Jan 2011, In : Malaria Journal. 10, 6 p., 9.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2010

Voiko pre-eklampsiaa ennustaa alkuraskaudessa? [pääkirjoitus]

Villa, P. M. & Laivuori, H. M., 2010, In : Duodecim. 126, 17, p. 1977-1979 3 p.

Research output: Contribution to journalArticleScientific

2009

Free fatty acid profiles in preeclampsia

Villa, P., Laivuori, H., Kajantie, E. & Kaaja, R., 2009, In : Prostaglandins, Leukotrienes & Essential Fatty Acids. 81, 1, p. 17-21 5 p.

Research output: Contribution to journalArticleScientificpeer-review

2004

Pre-eklampsia ja muu raskaudenaikainen verenpaineennousu

Laivuori, H. M. & Ylikorkala, O., 2004, Naistentaudit ja Synnytykset. Ylikorkala, O. & Kauppila, A. (eds.). 4 ed. Helsinki: Kustannus Oy Duodecim, p. 430-439 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Pre-eklampsian perinnöllisyys [katsausartikkeli]

Laivuori, H. M. & Kaaja, R., 2004, In : Suomen lääkärilehti. 33, p. 2921 4 p.

Research output: Contribution to journalArticleProfessional

Risk for subsequent coronary artery disease after preeclampsia

Haukkamaa, L., Salminen, M., Laivuori, H., Leinonen, H., Hiilesmaa, V. & Kaaja, R., 2004, In : American Journal of Cardiology. 93, p. 805-808 4 p.

Research output: Contribution to journalArticleScientificpeer-review