Projects per year
Organisation profile
Organisation Profile
Talman Lab
International and National Collaboration
Profiles
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Tanja Bruun
- Division of Pharmaceutical Chemistry and Technology - Doctoral Researcher
- Regenerative cardiac pharmacology
- Medicinal Chemistry research group
- Doctoral Programme in Drug Research
Person: U1 Research and teaching staff, Doctoral Researcher
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Tuuli Karhu
- Division of Pharmacology and Pharmacotherapy - University Lecturer
- Regenerative cardiac pharmacology
Person: U1 Research and teaching staff, U3 Research and teaching staff
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Lotta Pohjolainen
- Divisions of Faculty of Pharmacy - Grant-funded researcher
- Regenerative cardiac pharmacology
- Doctoral Programme in Drug Research
Person: Visiting scholar, U1 Research and teaching staff, Doctoral Researcher
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Virpi Talman
- Divisions of Faculty of Pharmacy - Title of Docent
- Division of Pharmacology and Pharmacotherapy - University Researcher
- Regenerative cardiac pharmacology
- Drug Research Program
- Doctoral Programme in Chemistry and Molecular Sciences - Supervisor for doctoral programme
- Doctoral Programme in Drug Research - Supervisor for doctoral programme
Person: U3 Research and teaching staff, Teaching and research personnel
Projects
- 1 Active
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Phenotypic characterisation of genetic cardiomyopathies and the effect of the GATA4-targeting compound on the phenotype of hiPSC-CMs
Pohjavaara, S. A., Talman, V., Kinnunen, S., Välimäki, M. & Ruskoaho, H.
01/05/2022 → …
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
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Affinity chromatography reveals direct binding of the GATA4-NKX2-5 interaction inhibitor (3i-1000) with GATA4
Jumppanen, M., Kinnunen, S. M., Zore, M., Välimäki, M. J., Talman, V., Boije af Gennäs, G., Ruskoaho, H. J. & Yli-Kauhaluoma, J., 18 Apr 2024, In: Scientific Reports. 14, 13 p., 8938.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
New SCN5A mutation P1891A causes left ventricular noncompaction and links Nav1.5 protein-protein interactions to cardiomyocyte proliferation and tissue compaction
Majid, Q., Prajapati, C., Liu, X., Kari-Koskinen, J., Karhu, T., Ruskoaho, H., E. Harding, S., Varjosalo, M., Aalto-Setälä, K. & Talman, V., 2024, (In preparation) In: Circulation Research.Research output: Contribution to journal › Article › Scientific › peer-review
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Switching of hypertrophic signalling towards enhanced cardiomyocyte identity and maturity by a GATA4-targeted compound
Pohjolainen, L., Kinnunen, S., Auno, S., Kiriazis, A., Pohjavaara, S. A., Kari-Koskinen, J., Zore, M., Jumppanen, M., Yli-Kauhaluoma, J., Talman, V., Ruskoaho, H. & Välimäki, M., 2 Jan 2024, In: Stem Cell Research & Therapy. 15, 18 p., 5.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
α-Melanocyte-stimulating hormone alleviates pathological cardiac remodeling via melanocortin 5 receptor
Suominen, A., Saldo Rubio, G., Ruohonen, S., Szabó, Z., Pohjolainen, L., Ghimire, B., Ruohonen, S. T., Saukkonen, K., Ijas, J., Skarp, S., Kaikkonen, L., Cai, M., Wradlaw, S. L., Ruskoaho, H., Talman, V., Savontaus, E., Kerkelä, R. & Rinne, P., 7 Mar 2024, In: EMBO Reports. 25, 4, p. 1987-2014 28 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Expanding the Paradigm of Structure-Based Drug Design: Molecular Dynamics Simulations Support the Development of New Pyridine-Based Protein Kinase C–Targeted Agonists
Lautala, S., Provenzani, R., Tarvainen, I., Sirna, K., Karhu, T., Grazhdankin, E., Lehtinen, A. K., S'ad, H., Koivuniemi, A., Xhaard, H., Tuominen, R. K., Talman, V., Bunker, A. E. & Yli-Kauhaluoma, J., 13 Apr 2023, In: Journal of Medicinal Chemistry. 66, 7, p. 4588-4602 15 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
Activities
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EFMC-ASMC 2023
Tanja Bruun (Poster Presentation)
3 Sept 2023 → 7 Sept 2023Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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High-Content Cellular Imaging User Meeting 2023
Virpi Talman (Attendee)
9 May 2023 → 10 May 2023Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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16th Annual FinPharmaNet Meeting 2022
Tanja Riina Bruun (Member of organizing committee)
13 Jun 2022 → 14 Jun 2022Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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EFMC-ISMC 2022, XXVII EFMC International Symposium on Medicinal Chemistry
Tanja Riina Bruun (Poster Presentation)
4 Sept 2022 → 8 Sept 2022Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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FIN3R - Improving the quality and translatability of biomedical research through 3R principles
Virpi Talman (Member of organizing committee)
7 Dec 2022 → 8 Dec 2022Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Prizes
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2019 Paul Dudley White International Scholar Award
Karhu, Tuuli (Recipient), 30 Jul 2019
Prize: Prizes and awards
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The Most Outstanding Pharmaceutical Research Article Award 2022
Talman, Virpi (Recipient), Ruskoaho, Heikki (Recipient) & Karhu, Tuuli (Recipient), 10 Nov 2022
Prize: Prizes and awards