Publications 2006 2020

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2019
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Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson's disease

Albert, K., Voutilainen, M. H., Domanskyi, A., Piepponen, T. P., Ahola, S., Tuominen, R. K., Richie, C., Harvey, B. K. & Airavaara, M., Mar 2019, In : Journal of Neuroscience Research. 97, 3, p. 346-361 16 p.

Research output: Contribution to journalArticleScientificpeer-review

2018

Combination of CDNF and Deep Brain Stimulation Decreases Neurological Deficits in Late-stage Model Parkinson's Disease

Huotarinen, A., Penttinen, A-M., Bäck, S., Voutilainen, M. H., Julku, U., Piepponen, T. P., Männistö, P. T., Saarma, M., Tuominen, R., Laakso, A. & Airavaara, M., 15 Mar 2018, In : Neuroscience. 374, p. 250-263 14 p.

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Open Access
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Open Access
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Pre-α-pro-GDNF and Pre-β-pro-GDNF Isoforms Are Neuroprotective in the 6-hydroxydopamine Rat Model of Parkinson's Disease

Penttinen, A-M., Parkkinen, I., Voutilainen, M. H., Koskela, M., Bäck, S., Their, A., Richie, C. T., Domanskyi, A., Harvey, B. K., Tuominen, R. K., Nevalaita, L., Saarma, M. & Airavaara, M., 20 Jun 2018, In : Frontiers in neurology. 9, 14 p., 457.

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2017

Depolarizing γ-aminobutyric acid contributes to glutamatergic network rewiring in epilepsy

Kourdougli, N., Pellegrino, C., Renko, J-M., Khirug, S., Chazal, G., Kukko-Lukjanov, T-K., Lauri, S. E., Gaiarsa, J-L., Zhou, L., Peret, A., Castrén, E., Tuominen, R. K., Crepel, V. & Rivera Baeza, C., Feb 2017, In : Annals of Neurology. 81, 2, p. 251-265 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Development and plasticity of meningeal lymphatic vessels

Antila, S., Karaman, S., Nurmi, H., Airavaara, M., Voutilainen, M. H., Mathivet, T., Chilov, D., Li, Z., Koppinen, T., Park, J-H., Fang, S., Aspelund, A., Saarma, M., Eichmann, A., Thomas, J-L. & Alitalo, K., Dec 2017, In : Journal of Experimental Medicine. 214, 12, p. 3645-3667 23 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Intrastriatally Infused Exogenous CDNF Is Endocytosed and Retrogradely Transported to Substantia Nigra

Mätlik, K., Vihinen, A. H., Bienemann, A., Palgi, J., Voutilainen, M. H., Booms, S., Lindahl, M. S., Jokitalo, E. S., Saarma, M., Huttunen, H. J., Airavaara, M. T. & Arumäe, U., 20 Feb 2017, In : eNeuro. 4, 1, 15 p., e0128-16.2017.

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Open Access
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2016

Characterization of a new low-dose 6-hydroxydopamine model of Parkinson's disease in rat

Penttinen, A-M., Suleymanova, I., Albert, K., Anttila, J., Voutilainen, M. & Airavaara, M., Apr 2016, In : Journal of Neuroscience Research. 94, 4, p. 318-328 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Differentiation and molecular heterogeneity of inhibitory and excitatory neurons associated with midbrain dopaminergic nuclei

Lahti, L., Haugas, M., Tikker, L., Airavaara, M., Voutilainen, M., Anttila, J., Kumar, S., Inkinen, C., Salminen, M. & Partanen, J., 1 Feb 2016, In : Development. 143, 3, p. 516-529 14 p.

Research output: Contribution to journalArticleScientificpeer-review

2014

Still a long way to go to achieve multidisciplinarity for the benefit of patients: commentary on the ESMO position paper (Annals of Oncology 25(1): 9-15, 2014)

Valentini, V., Abrahamsson, P. -A., Aranda, S. K., Astier, A., Audisio, R. A., Boniol, M., Bonomo, L., Brunelli, A., Bultz, B., Chiti, A., De Lorenzo, F., Eriksen, J. G., Goh, V., Gospodarowicz, M. K., Grassi, L., Kelly, J., Kortmann, R. D., Kutluk, T., Plate, A., Poston, G. & 7 others, Saarto, T., Soffietti, R., Torresin, A., van Harten, W. H., Verzijlbergen, J. F., von Kalle, C. & Poortmans, P., Sep 2014, In : Annals of Oncology. 25, 9, p. 1863-1865 4 p.

Research output: Contribution to journalArticleScientific

2013

Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's disease

Bäck, S., Peränen, J., Galli, E., Pulkkila, P., Lonka-Nevalaita, L., Tamminen, T., Voutilainen, M. H., Raasmaja, A., Saarma, M., Männistö, P. T. & Tuominen, R. K., Mar 2013, In : Brain and Behavior. 3, 2, p. 75-88 14 p.

Research output: Contribution to journalArticleScientificpeer-review

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2011

CDNF Protects the Nigrostriatal Dopamine System and Promotes Recovery After MPTP Treatment n Mice

Airavaara, M., Harvey, B. K., Voutilainen, M. H., Chou, J., Lindholm, P., Lindahl, M., Tuominen, R. K., Saarma, M., Wang, Y. & Hoffer, B., 2011, In : Cell Transplantation. 20, Supplement 1, p. 544-545 2 p.

Research output: Contribution to journalArticleScientificpeer-review

Chronic infusion of CDNF prevents 6-OHDA-induced deficits in a rat model of Parkinson's disease

Voutilainen, M. H., Back, S., Peranen, J., Lindholm, P., Raasmaja, A., Mannisto, P. T., Saarma, M. & Tuominen, R. K., 2011, In : Experimental Neurology. 228, 1, p. 99-108 10 p.

Research output: Contribution to journalArticleScientificpeer-review

2009

Mesencephalic astrocyte-derived neurotrophic factor is neurorestorative in rat model of Parkinson's Disease

Voutilainen, M., Bäck, S., Pörsti, E., Toppinen, L., Lindgren, L., Lindholm, P., Peränen, J., Saarma, M. & Tuominen, R. K., 2009, In : Journal of Neuroscience. 29, 30, p. 9651-9659 9 p.

Research output: Contribution to journalArticleScientificpeer-review

2007

Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo

Lindholm, P., Voutilainen, M., Lauren, J., Peränen, J., Leppänen, V-M., Andressoo, J-O., Lindahl, M., Janhunen, S., Kalkkinen, N., Timmusk, T., Tuominen, R. K. & Saarma, M., 2007, In : Nature. 448, 7147, p. 73-78 6 p.

Research output: Contribution to journalArticleScientificpeer-review

2006

C3-halogenation of cytisine generates potent and efficacious nicotinic receptor agonists

Abin -Carriquiry, J. A., Voutilainen, M., Barik, J., Cassels, B., Iturriaga-Vasquez, P., Bermudez, I., Durand, C., Dajas, F. & Wonnacott, S., 2006, In : European Journal of Pharmacology.

Research output: Contribution to journalArticleScientificpeer-review