Research Programs Unit

  • Finland

Publications 1966 2020

Filter
Meeting Abstract
2019

Brain metabolome during anesthesia - similarities and differences between post-ictal state

Kohtala, S., Kärkkäinen, O. & Rantamäki, T., 2019, In : European Neuropsychopharmacology. 29, p. S645-S646 2 p.

Research output: Contribution to journalMeeting AbstractResearch

GENETICS OF HUMAN PLASMA LIPIDOME AND ITS LINK TO DISEASES SUSCEPTIBILITY

SK Serv, T FinnGen Project, Tabassum, R., Rämö, J. T., Ripatti, P., Koskela, J. T., Kurki, M., Karjalainen, J., Palta, P., Hassan, S., Nunez-Fontarnau, J., Kiiskinen, T. T. J., Soderlund, S., Matikainen, N., Laivuori, H., Havulinna, A. S., Salomaa, V., Pirinen, M., Jauhiainen, M., Daly, M. J. & 3 others, Palotie, A., Taskinen, M. R. & Ripatti, S., Aug 2019, In : Atherosclerosis. 287, p. E14-E15 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Injury Severity and Extracranial Injuries Are Associated with Delayed Return to Work in Mild Traumatic Brain Injury Patients

Huovinen, A., Isokuortti, H., Marinkovic, I., Vanni, S. & Melkas, S., 2 May 2019, In : Brain Injury. 33, p. 128-129 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Intracranial Traumatic Lesions Delay Return to Work in Mild Traumatic Injury Patients

Huovinen, A., Marinkovic, I., Isokuortti, H., Korvenoja, A., Vanni, S. & Melkas, S., 2 May 2019, In : Brain Injury. 33, p. 130-131 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

POLYGENIC HYPERLIPIDEMIA INCREASES CORONARY ARTERY DISEASE RISK IN THE UK BIOBANK

Ripatti, P., Ramo, J. T., Soderlund, S., Surakka, I., Havulinna, A. S., Widen, E., Palta, P., Freimer, N. B., Salomaa, V., Pirinen, M., Palotie, A., Taskinen, M. R. & Ripatti, S., Aug 2019, In : Atherosclerosis. 287, p. E92-E92 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Psychiatric Disorders and Return to Work after Mild Traumatic Brain Injury

Marinkovic, I., Isokuortti, H., Huovinen, A., Korvenoja, A., Vataja, R. & Melkas, S., 2 May 2019, In : Brain Injury. 33, p. 153-153 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2018

Cardiovascular autonomic function after simultaneous pancreas-kidney and kidney-alone transplantation in patients with diabetes

Paajanen, H., Bordino, M., Sandelin, A., Ekstrand, A., Lempinen, M., Forsblom, C., Bernardi, L. & Groop, P-H., 2018, (Accepted/In press) In : Diabetes Care. 1 p.

Research output: Contribution to journalMeeting AbstractResearch

Clinical and Genetic Characterization of Canine Vitreous Degeneration

Kaukonen, M. & Lohi, H., Jul 2018, In : Investigative Ophthalmology & Visual Science. 59, 9, 2 p., 6042.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

Combined Targeting of BET Family Proteins and BCL2 Is Synergistic in Acute Myeloid Leukemia Cells Overexpressing S100A8 and S100A9

Karjalainen, R., Liu, M., Kumar, A., Parsons, A., He, L., Malani, D. R., Kontro, M., Porkka, K. & Heckman, C. A., 2018, In : Blood. 132

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

COSTS AND HEALTH SERVICE USE ASSOCIATED WITH FLUOROQUINOLONE-RELATED TENDON INJURIES

Saarukka, L., Backman, J. T. & Blom, M., Oct 2018, In : Value in Health. 21, p. S293-S293 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Eltrombopag Promotes Megakaryocyte Survival and Signaling in the Presence of Specific Cytotoxic Agents

Javarappa, K. K., Tsallos, D., Zagidullin, B., Saad, J., Tang, J., Ramos, P. M., Pallaud, C. & Heckman, C. A., 2018, In : Blood. 132

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Enantiospecific Pharmacogenomics of Fluvastatin

Hirvensalo, P., Tornio, A., Neuvonen, M., Kiander, W., Kidron, H., Paile-Hyvärinen, M., Tapaninen, T., Backman, J. & Niemi, M., May 2018, In : Basic & Clinical Pharmacology & Toxicology. 123, p. 7-7 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Melatonin receptor type 1A gene linked to intolerance to shift work and Alzheimer's disease in old age

Sulkava, S., Muggalla, P., Sulkava, R., Ollila, H. M., Peuralinna, T., Myllykangas, L., Helisalmi, S., Soininen, H., Polvikoski, T., Hiltunen, M., Tienari, P. J., Huttunen, H. J. & Paunio, T., Sep 2018, In : Journal of Sleep Research. 27, Supplement 1, 1 p., P007.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Multi-Parametric Single Cell Profiling Defines Distinct Drug Responses in Healthy Hematological Cell Lineages That Are Retained in Corresponding Malignant Cell Types

Majumder, MM., Leppä, A-M., Hellesøy, M., Dowling, P., Malyutina, A., Bazou, D., Andersson, E. I., Parsons, A., Tang, J., Kallioniemi, O-P., Mustjoki, S. M., O'Gorman, P., Wennerberg, J. K., Porkka, K. V. K., Gjertsen, B-T. & Heckman, C. A., 2018, In : Blood. 132

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

Oncolytic Adenoviruses Encapsulated into the Extracellular Vesicles as Carriers for Cancer Drug Delivery

Garofalo, M., Saari, H., Somersalo, P., Crescenti, D., Kuryk, L., Aksela, L., Capasso, C., Madetoja, M., Koskinen, K., Makitie, A., Jalasvuori, M., Cerullo, V., Ciana, P. & Yliperttula, M., May 2018, In : Molecular therapy. 26, 5, p. 203-203 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2017

Characterization of Immunological Profiles with Clinical Significance in Patients with Classical Hodgkin Lymphoma

Karihtala, K., Leivonen, S-K., Karjalainen-Lindsberg, M-L. & Leppa, S., 7 Dec 2017, In : Blood. 130, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

DISC1 GENE NETWORK MUTATIONS IN MAJOR MENTAL ILLNESS

Sinha, V., Ortega-Alonso, A., Ukkola-Vuoti, L., Hovatta, I., Haukka, J., Torniainen, M., Therman, S., Cannon, T., Kaprio, J., Lonnqvist, J., Partonen, T., Isometsa, E., Paunio, T., Suvisaari, J. & Hennah, W., Oct 2017, In : European Neuropsychopharmacology. 27, p. S406-S407 2 p., M57.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Exploration of tissue morphologies in breast cancer samples using unsupervised machine learning

Turkki, R., Bychkov, D., Linder, N., Isola, J., Joensuu, H. T. & Lundin, J., 1 Jul 2017, In : Cancer Research. 77, 13 Supplement, p. 673 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Fluoroquinolone-Related Adverse Events Resulting In Health Care Use And Costs: A Systematic Review

Kuula, L. SM., Viljemaa, K. M., Backman, J. T. & Blom, M. L. J., Oct 2017, In : Value in Health. 20, p. A669-A670 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

GDNF CONTROLS URETER LENGTH BY REGULATING COLLECTING DUCT PROGENITOR EXPANSION

Li, H., Jakobson, M., Ola, R., Sariola, H., Andressoo, J. & Kuure, S., Sep 2017, In : Pediatric Nephrology. 32, 9, p. 1651-1651 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

High Amount of PD-L1+Tumor Associated Macrophages Is Associated with Better Survival in Patients with Primary Testicular Lymphoma

Pollari, M., Bruck, O., Leivonen, S-K., Pellinen, T., Vahamurto, P., Karjalainen-Lindsberg, M-L., Mannisto, S., Kellokumpu-Lehtinen, P-L., Mustjoki, S. & Leppa, S., 7 Dec 2017, In : Blood. 130, Suppl 1, p. Meeting Abstract: 2761 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Homology between cancer and viral epitopes as criteria to design improved cancer vaccines

Capasso, C., Whalley, T., Marwah, V. S., Serafin, A., Fusciello, M., Feola, S., Martins, B., Greco, D., Szomolay, B. & Cerullo, V., Dec 2017, In : Annals of Oncology. 28, 1 p., 63P.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

IMMUNOLOGICAL CHARACTERIZATION OF PH plus ALL BONE MARROW BY MULTIPLEX IMMUNOHISTOCHEMISTRY

Hohtari, H., Bruck, O., Blom, S., Turkki, R., Ribeiro, A., Sinisalo, M., Kovanen, P., Kallioniemi, O., Pellinen, T., Porkka, K. & Mustjoki, S., 26 Jun 2017, In : Haematologica. 102, p. 654-654 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Low Expression of T/NK-Cell Signature Predicts Poor Survival in Patients with Primary Testicular and Diffuse Large B-Cell Lymphoma

Leivonen, S-K., Pollari, M., Bruck, O., Pellinen, T., Karjalainen-Lindsberg, M-L., Mannisto, S., Kellokumpu-Lehtinen, P-L., Mustjoki, S. & Leppa, S., 7 Dec 2017, In : Blood. 130, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Th1/2 Immune Response Signature Predicts Outcome after Dose-Dense Immunochemotherapy in Patients with High Risk Diffuse Large B-Cell Lymphoma - Results from Nordic Lymphoma Group Trials

Autio, M., Leivonen, S-K., Jorgensen, J. M., Karjalainen-Lindsberg, M-L., Beiske, K., Holte, H. & Leppä, S., 7 Dec 2017, In : Blood. 130, 2 p., 4008.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Uptake and functionality of prostate cancer extracellular vesicles depends on the metastatic stage of the parent cells

Lazaro Ibanez, E., Neuvonen, K. M., Takatalo-Laine, S. M., Thanigai Arasu, U., Capasso, C., Rhim, J., Rilla, K., Yliperttula, M. L. & Siljander, P. R-M., May 2017, In : Journal of Extracellular Vesicles. 6, sup1

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

Wnt pathway activation in 3D nephron progenitor culture facilitates self-organization, expansion, and differentiation

Dapkunas, A., Rantanen, V., Kuure, S., Sainio, K. & Sariola, H., Jul 2017, In : Mechanisms of Development. 145, p. S162-S163 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2016

Cause of Stroke is not Associated With the Risk of Symptomatic Post-thrombolytic Intracerebral Hemorrhage

Curtze, S., Sibolt, G., Melkas, S., Mustanoja, S., Haapaniemi, E., Putaala, J., Sairanen, T., Tiainen, M., Tatlisumak, T. & Strbian, D., Feb 2016, In : Stroke. 47, 3 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

CML Patients with Primary Resistance or Suboptimal Response to TKI Therapy Have Variants in Genes Affecting Drug Absorption and Metabolism

Pietarinen, P., Koskenvesa, P., Klievink, J., Porkka, K., Niemi, M. & Mustjoki, S., 2 Dec 2016, In : Blood. 128, 22, 4 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Dasatinib Exerts Differential Effects on Normal and BCR-ABL Positive Hematopoietic Cells in a Transgenic Mouse Model of Chronic Phase-CML

Schubert, C., Chatain, N., Braunschweig, T., Schemionek, M., Feldberg, K., Hoffmann, M., Brummendorf, T. H., Mustjoki, S., Dufva, O. & Koschmieder, S., 2 Dec 2016, In : Blood. 128, 22, 6 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Dose-Dense Chemoimmunotherapy Including Early CNS Prophylaxis for High-Risk DLBCL. -Final Analysis from a Nordic Phase II Study (the CHIC trial)

Leppa, S., Joergensen, J., Tierens, A., Ostlie, I., Fagerli, U. M., Brown, P. D. N., Larsen, T. S., Mannisto, S., Munksgaard, L., Maisenholder, M., Vasala, K., Meyer, P., Jerkeman, M., Bjorkholm, M., Fluge, O., Jyrkkio, S., Ralfkiaer, E., Spetalen, S., Karjalainen-Lindsberg, M-L. & Holte, H., 2 Dec 2016, In : Blood. 128, 22, 6 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Effects of a lifestyle intervention during pregnancy and 1-year postpartum - results from the RADIEL study

Huvinen, H., Koivusalo, S., Stach-Lempinen, B., Kautiainen, H. & Eriksson, J., 26 Feb 2016, In : Gynecological Endocrinology. 32, p. 161-161 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Haptoglobin Hp2 Variant Associates With an Increased Risk of Ischemic Cardiovascular Death After First-ever Stroke.

Ijas, P., Melkas, S., Saksi, J., Jula, A., Jauhiainen, M., Pohjasvaara, T., Kaste, M., Karhunen, P. J., Lindsberg, P. & Erkinjuntti, T., Feb 2016, In : Stroke. 47, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Immune cell profiling in CML bone marrow by multiplex IHC

Bruck, O., Blom, S., Turkki, R., Kovanen, P., Ribeiro, A., Linder, N., Lundin, J., Kallioniemi, O., Pellinen, T. & Mustjoki, S., Nov 2016, In : Annals of Oncology. 27, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Immune Cell Profiling in CML Bone Marrow By Multiplex Immunohistochemistry

Oscar, B., Blom, S., Turkki, R., Kovanen, P. E., Ribeiro, A., Linder, N., Lundin, J., Kallioniemi, O., Pellinen, T. & Mustjoki, S., 2 Dec 2016, In : Blood. 128, 22, 4 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Impact of Rituximab and Methotrexate on the Survival of the Patients with Sinonasal Tract Diffuse Large B-Cell Lymphoma

Vahamurto, P., Mannisto, S., Pollari, M., Karjalainen-Lindsberg, M-L., Makitie, A. A. & Leppa, S., 2 Dec 2016, In : Blood. 128, 22, 6 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Integrative Genetic and Clinical Analysis through Whole Exome Sequencing in 1001 Diffuse Large B Cell Lymphoma (DLBCL) Patients Reveals Novel Disease Drivers and Risk Groups

Zhang, J., Reddy, A., Love, C., Moffitt, A. B., Rajagopalan, D., Leppa, S., Pasanen, A., Meriranta, L., Karjalainen-Lindsberg, M-L., Norgaard, P. H., Pederson, M., Gang, A. O., Hogdall, E., Richards, K. L., Fedoriw, Y. D., Bernal-Mizrachi, L., Koff, J. L., Staton, A. D., Flowers, C., Paltiel-Clarfield, O. & 23 others, Goldschmidt, N., Calaminici, M., Clear, A. J., Gribben, J., Nguyen, E., Czader, M., Ondrejka, S. L., Collie, A., Hsi, E. D., Au-Yeung, R., Yok-Lam, K., Choi, W. L., Srivastava, G., Evens, A. M., Pilichowska, M., Sengar, M., Reddy, N., Li, S., Jaffe, E. S., Tzeng, T., Datta, J., Dunson, D. & Dave, S., 2 Dec 2016, In : Blood. 128, 22, 6 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Low Expression and Somatic Mutations of the KLHL6 Gene Predict Poor Survival in Patients with Activated B-Cell like Diffuse Large B-Cell Lymphoma

Meriranta, L., Pasanen, A., Cervera, A., Holte, H., Lehtonen, R., Hautaniemi, S. & Leppa, S., 2 Dec 2016, In : Blood. 128, 22, 4 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Low Expression of the CIITA Gene Predicts Poor Outcome in Diffuse Large B-Cell Lymphoma

Autio, M., Jantti, K., Cervera, A., Hautaniemi, S. & Leppa, S., 2 Dec 2016, In : Blood. 128, 22, 3 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Lymphoid somatic mutations in multiple sclerosis

Valori, M., Jansson, L., Kiviharju, A., Porkka, K., Ellonen, P., Mustjoki, S. & Tienari, P., Sep 2016, In : Multiple Sclerosis Journal . 22, p. 170-171 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Molecular Characterization of Cytotoxic T Cell Repertoire in Aplastic Anemia and Myelodysplastic Syndromes

Lundgren, S. A., Keränen, M. A., Savola, P., Park, G., Ebeling, F., Walldin, G., Hellstroem-Lindsberg, E. & Mustjoki, S., 2 Dec 2016, In : Blood. 128, 22, 4 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Mutational Landscape of Aggressive Natural Killer Cell Leukemia and Drug Sensitivity Profiling Reveal Therapeutic Options in Natural Killer Cell Malignancies

Dufva, O., Kankainen, M., Kelkka, T., Awad, S. A., Sekiguchi, N., Yadav, B., Eldfors, S., Kuusanmaki, H., Andersson, E. I., Malani, D., Pietarinen, P., Saikko, L., Kovanen, P. E., Suzumiya, J., Suzuki, R., Ko, Y. H., Kim, W. S., Chuang, S-S., Loughran, T. P., Chan, W. C. & 4 others, Ohshima, K., Aittokallio, T., Ishida, F. & Mustjoki, S., 2 Dec 2016, In : Blood. 128, 22, 4 p., 2921.

Research output: Contribution to journalMeeting AbstractResearch

Novel Mutations in Patients with Blast Crisis or Accelerated Phase Chronic Myeloid Leukemia

Awad, S. A., Kankainen, M., Eldfors, S., Kytola, S., Ellonen, P., Kamel, M., Heckman, C. A., Porkka, K. & Mustjoki, S., 2 Dec 2016, In : Blood. 128, 22, 3 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Pan-Hematopoietic Cancer Gene Expression Analysis Identifies Immunologically Active Acute Myeloid Leukemia Subtypes

Dufva, O., Polonen, P., Keranen, M. A., Liuksiala, T., Lin, J., Mehtonen, J., Hayrynen, S., Granberg, K., Nykter, M., Lohi, O., Heinaniemi, M. & Mustjoki, S., 2 Dec 2016, In : Blood. 128, 22, 6 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Somatic MED12 mutations in hematological malignancies

Heikkinen, T., Kampjarvi, K., Leppa, S., Hokland, P., Kuusanmaki, H., Mustjoki, S., Sinisalo, M., Heckman, C., Kontro, M. & Vahteristo, P., Jul 2016, In : Cancer Research. 76, 3 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

UNSTABLE LDL - NOVEL MECHANISM OF ATHEROGENESIS AND LINK TO CARDIOVASCULAR DEATHS

Ruuth, M., Nguyen, S. D., Vihervaara, T., Laajala, T. D., Uusitupa, M., Schwab, U., Savolainen, M., Sinisalo, J., Aittokallio, T., Kakela, R., Jauhiainen, M., Kovanen, P. & Oorni, K., Sep 2016, In : Atherosclerosis. 252, p. E208-E208 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review