Projects per year
Organization profile
Organisation Profile
We aim towards deep understanding of RNA virus replication at the molecular level. Through the discovery of basic mechanistic principles, we develop new and general antiviral strategies.
International and National Collaboration
Publications and projects within past five years.
Profiles
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Tero Ahola
- Department of Microbiology - University Lecturer
- Helsinki One Health (HOH)
- RNA virus replication and antivirals
- Doctoral Programme in Drug Research - Supervisor for doctoral programme
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
- Doctoral Programme in Microbiology and Biotechnology - Supervisor for doctoral programme
Person: U3 Research and teaching staff, UH, Teaching and research personnel
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Sari Mattila
- Department of Microbiology - Postdoctoral Researcher
- RNA virus replication and antivirals
Person: U2 Teaching and research staff, UH
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Mohammadreza Sadeghi
- Department of Microbiology - Docent Contract, Title of Docent
- RNA virus replication and antivirals
Person
Research Units
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Viral replication complexes: Virus replication machineries – Structure and function
Pietilä, M. & Pham, M. T.
01/01/2017 → …
Project: University of Helsinki Three-Year Research Project
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FUNREC: Functional reconstitution of membrane rearrangements induced by viral replication
Pietilä, M. & Lång, M.
01/09/2014 → 31/08/2017
Project: Research project
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Center of Excellence in Virus Research (CoE_VIRRES)
Bamford, D., Bamford, J., Butcher, S., Oksanen, H. M., Poranen, M., Roine, E., Kainov, D., Tuma, R., Ravantti, J., Huiskonen, J., Jäälinoja, H., Ora, A., Hattula, K., Ziedaite, G., Romanovskaya, A., Lisal, J., Buivydas, A., Redder, P., Domanska, A., Vilen, S., Manole, V., Happonen, L., Seitsonen, J., Liljeroos, L., Suchanova, B., Falck, S., Daugelavicius, R., Golubtsov, A., Yuan, P., Anastasina, M., Karhu, N. J., Koivunen, M., Laurinavicius, S., Wallin, A., Aalto, A. P., Sarin, P., Atanasova, N., Sun, X., Pietilä, M., Krupovic, M., Cvirkaite-Krupovic, V., Kukkaro, P. & Pirttimaa, M.
25/02/2011 → 31/12/2016
Project: Research Evaluation 2011
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Alphavirus RNA replication in vertebrate cells
Ahola, T., McInerney, G. M. & Merits, A., 2021, In: Advances in Virus Research. 111, p. 111-156Research output: Contribution to journal › Review Article › peer-review
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Macrodomain binding compound MRS 2578 inhibits alphavirus replication
Mattila, S., Merilahti, P., Wazir, S., Quirin, T., Maksimainen, M., Zhang, Y., Xhaard, H., Lehtiö, L. & Ahola, T., 2021, In: Antimicrobial Agents and Chemotherapy. 65, 12, e01398-21.Research output: Contribution to journal › Article › peer-review
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RNA Viruses in Aquatic Unicellular Eukaryotes
Sadeghi, M., Tomaru, Y. & Ahola, T., 2021, In: Viruses-Basel. 13, 3, 21 p., 362.Research output: Contribution to journal › Review Article › peer-review
Open AccessFile -
Enzymatically synthesized 2'-fluoro-modified Dicer-substrate siRNA swarms against herpes simplex virus demonstrate enhanced antiviral efficacy and low cytotoxicity
Levanova, A., Kalke, K., Lund, L., Sipari, N., Sadeghi, M., Nyman, M., Paavilainen, H., Hukkanen, V. & Poranen, M., Oct 2020, In: Antiviral Research. 182, 8 p., 104916.Research output: Contribution to journal › Article › peer-review
Open Access -
Virusten lisääntyminen ja evoluutio
Ahola, T. & Söderlund-Venermo, M., 2020, Mikrobiologia: Mikrobiologia, immunologia ja infektiosairaudet 1. Heikkinen, T., A. J., Meri, S., Vapalahti, O. & Vuopio, J. (eds.). Helsinki: Duodecim, p. 491-501Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional
Activities
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Avian influenza virus infection in human innate immune cells - doctoral thesis of Veera Westenius, Aalto University
Tero Ahola (Opponent)
22 Mar 2019Activity: Examination types › Opponent of doctoral dissertation
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Antimicrobial Agents and Chemotherapy (Journal)
Tero Ahola (Member of editorial board)
2019 → 2021Activity: Publication peer-review and editorial work types › Editor of research journal
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American Society for Virology 2017 Meeting
Maija Pietilä (Attendee)
24 Jun 2017 → 28 Jun 2017Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Viruses (Journal)
Tero Ahola (Editor)
2017 → 2018Activity: Publication peer-review and editorial work types › Editor of special theme number
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Positive-Strand RNA Viruses
Maija Pietilä (Poster Presentation)
1 May 2016 → 5 May 2016Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars