Projects per year
Organisation profile
We aim towards deep understanding of RNA virus replication at the molecular level. Through the discovery of basic mechanistic principles, we develop new and general antiviral strategies.
International and National Collaboration
Publications and projects within past five years.
Profiles
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Tero Ahola
- Department of Microbiology - Senior University Lecturer
- Helsinki One Health (HOH)
- RNA virus replication and antivirals
- Doctoral Programme in Drug Research - Supervisor for doctoral programme
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
- Doctoral Programme in Microbiology and Biotechnology - Supervisor for doctoral programme
Person: U3 Research and teaching staff, UH , Teaching and research personnel
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Sari Mattila
- Department of Microbiology - Visiting scholar
- RNA virus replication and antivirals
Person: Visiting scholar, UH
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Tania Quirin
- Department of Virology - Postdoctoral Researcher
- RNA virus replication and antivirals
Person: U2 Teaching and research staff, UH
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Mohammadreza Sadeghi
- Department of Microbiology - Docent Contract, Title of Docent, Postdoctoral Researcher
- RNA virus replication and antivirals
Person: U2 Teaching and research staff
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Viral replication complexes: Virus replication machineries – Structure and function
Pietilä, M. & Pham, M. T.
01/01/2017 → …
Project: University of Helsinki Three-Year Research Project
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FUNREC: Functional reconstitution of membrane rearrangements induced by viral replication
Pietilä, M. & Lång, M.
01/09/2014 → 31/08/2017
Project: Research project
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Center of Excellence in Virus Research (CoE_VIRRES)
Bamford, D. H., Bamford, J., Butcher, S., Oksanen, H. M., Poranen, M., Roine, E., Kainov, D., Tuma, R., Ravantti, J., Huiskonen, J., Jäälinoja, H., Ora, A., Hattula, K., Ziedaite, G., Romanovskaya, A., Lisal, J., Buivydas, A., Redder, P., Domanska, A., Vilen, S., Manole, V., Happonen, L., Seitsonen, J., Liljeroos, L., Suchanova, B., Falck, S., Daugelavicius, R., Golubtsov, A., Yuan, P., Anastasina, M., Karhu, N. J., Koivunen, M., Laurinavicius, S., Wallin, A., Aalto, A. P., Sarin, P., Atanasova, N., Sun, X., Pietilä, M., Krupovic, M., Cvirkaite-Krupovic, V., Kukkaro, P. & Pirttimaa, M.
25/02/2011 → 31/12/2016
Project: Research Evaluation 2011
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Positive-strand RNA viruses-a Keystone Symposia report
Cable, J., Denison, M. R., Kielian, M., Jackson, W. T., Bartenschlager, R., Ahola, T., Mukhopadhyay, S., Fremont, D. H., Kuhn, R. J., Shannon, A., Frazier, M. N., Yuen, K-Y., Coyne, C. B., Wolthers, K. C., Ming, G-L., Guenther, C. S., Moshiri, J., Best, S. M., Schoggins, J. W., Jurado, K. A., & 25 others, Mar 2023, In: Annals of the New York Academy of Sciences. 1521, 1, p. 46-66 21 p.Research output: Contribution to journal › Article › Scientific › peer-review
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The infectivity of SARS-CoV-2 progeny virions requires the activity of host cell N-myristoyltransferases and it is severely compromised by their inhibition
Saber, H., Ojha, R. K., Quirin, T., Kant, R., Strandin, T., Kareinen, L., Yak, N., Sironen, T., Vapalahti, O., Balistreri, G. & Joensuu, M., 7 Mar 2023, In: bioRxiv.Research output: Contribution to journal › Article › Scientific
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Alphavirus RNA replication in vertebrate cells
Ahola, T., McInerney, G. M. & Merits, A., 2021, In: Advances in Virus Research. 111, p. 111-156Research output: Contribution to journal › Review Article › peer-review
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Macrodomain binding compound MRS 2578 inhibits alphavirus replication
Mattila, S., Merilahti, P., Wazir, S., Quirin, T., Maksimainen, M., Zhang, Y., Xhaard, H., Lehtiö, L. & Ahola, T., 2021, In: Antimicrobial Agents and Chemotherapy. 65, 12, e01398-21.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
RNA Viruses in Aquatic Unicellular Eukaryotes
Sadeghi, M., Tomaru, Y. & Ahola, T., 2021, In: Viruses (Basel). 13, 3, 21 p., 362.Research output: Contribution to journal › Review Article › peer-review
Open AccessFile
Activities
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Chikungunya virus nonstructural protein 1 as an antiviral target - doctoral thesis of Kristina Kovacikova, Leiden University
Tero Ahola (Opponent)
20 Apr 2021Activity: Examination types › Opponent of doctoral dissertation
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Avian influenza virus infection in human innate immune cells - doctoral thesis of Veera Westenius, Aalto University
Tero Ahola (Opponent)
22 Mar 2019Activity: Examination types › Opponent of doctoral dissertation
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Antimicrobial Agents and Chemotherapy (Journal)
Tero Ahola (Member of editorial board)
2019 → 2021Activity: Publication peer-review and editorial work types › Editor of research journal
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American Society for Virology 2017 Meeting
Maija Pietilä (Attendee)
24 Jun 2017 → 28 Jun 2017Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Viruses (Basel) (Journal)
Tero Ahola (Editor)
2017 → 2018Activity: Publication peer-review and editorial work types › Editor of special theme number