• P.O. Box 56 (Viikinkaari 9), Biocenter 1

    00014 University of Helsinki

    Finland

Organization profile

Organisation Profile

We aim towards deep understanding of RNA virus replication at the molecular level. Through the discovery of basic mechanistic principles, we develop new and general antiviral strategies.

International and National Collaboration Publications and projects within past five years.

Projects 2014 2017

Viral replication complexes: Virus replication machineries – Structure and function

Pietilä, M. & Pham, M. T.

01/01/2017 → …

Project: University of Helsinki Three-Year Research Project

Publications 2002 2019

Midbiotics: conjugative plasmids for genetic engineering of natural gut flora

Ruotsalainen, P., Penttinen, R., Mattila, S. & Jalasvuori, M., 5 Apr 2019, In : Gut Microbes. p. 1-11 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Purification of Highly Active Alphavirus Replication Complexes Demonstrates Altered Fractionation of Multiple Cellular Membranes

Pietila, M. K., van Hemert, M. J. & Ahola, T., Apr 2018, In : Journal of Virology. 92, 8, 19 p., ARTN e01852-17.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

The RNA Capping Enzyme Domain in Protein A is Essential for Flock House Virus Replication

Quirin, T., Chen, Y., Pietilä, M. K., Guo, D. & Ahola, T., 9 Sep 2018, In : Viruses. 10, 9, 18 p., 483.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Alphavirus polymerase and RNA replication

Pietilä, M., Hellström, K. & Ahola, T., 15 Apr 2017, In : Virus Research. 234, p. 44-57 14 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
File

Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy.

Li, X., Wu, Z., An, X., Mei, Q., Bai, M., Hanski, L., Li, X., Ahola, T. & Han, W., 2017, In : eLife. 6, 34 p., e27301.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Activities 2010 2019

Avian influenza virus infection in human innate immune cells - doctoral thesis of Veera Westenius, Aalto University

Tero Ahola (Opponent)
22 Mar 2019

Activity: Examination typesOpponent of doctoral dissertation

Antimicrobial Agents and Chemotherapy (Journal)

Tero Ahola (Member of editorial board)
20192021

Activity: Publication peer-review and editorial work typesEditor of research journal

American Society for Virology 2017 Meeting

Maija Pietilä (Attendee)
24 Jun 201728 Jun 2017

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

Viruses (Journal)

Tero Ahola (Editor)
20172018

Activity: Publication peer-review and editorial work typesEditor of special theme number

PhD thesis - Sari Mattila

Maija Pietilä (Pre-examiner)
2016

Activity: Examination typesPre-examiner of doctoral thesis