Projects per year
Organisation profile
Organisation Profile
We aim towards deep understanding of RNA virus replication at the molecular level. Through the discovery of basic mechanistic principles, we develop new and general antiviral strategies.
International and National Collaboration
Publications and projects within past five years.
Profiles
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Tero Ahola
- Department of Microbiology - Senior University Lecturer
- Helsinki One Health (HOH)
- RNA virus replication and antivirals
- Doctoral Programme in Drug Research - Supervisor for doctoral programme
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
- Doctoral Programme in Microbiology and Biotechnology - Supervisor for doctoral programme
Person: U3 Research and teaching staff, UH , Teaching and research personnel
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Sari Mattila
- Institute of Biotechnology - Laboratory Coordinator
- RNA virus replication and antivirals
Person: M5 Teaching and research support staff, UH
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Tania Quirin
- Institute of Biotechnology - Postdoctoral Researcher
- RNA virus replication and antivirals
Person: U2 Teaching and research staff, UH
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Mohammadreza Sadeghi
- Department of Microbiology - Docent Contract, Title of Docent
- RNA virus replication and antivirals
Person
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Viral replication complexes: Virus replication machineries – Structure and function
Pietilä, M. (Project manager) & Pham, M. T. (Participant)
01/01/2017 → …
Project: University of Helsinki Three-Year Research Project
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FUNREC: Functional reconstitution of membrane rearrangements induced by viral replication
Pietilä, M. (Project manager) & Lång, M. (Participant)
01/09/2014 → 31/08/2017
Project: Research project
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Center of Excellence in Virus Research (CoE_VIRRES)
Bamford, D. H. (Principal Investigator), Bamford, J. (Participant), Butcher, S. (Principal Investigator), Oksanen, H. M. (Principal Investigator), Poranen, M. (Principal Investigator), Roine, E. (Principal Investigator), Kainov, D. (Principal Investigator), Tuma, R. (Participant), Ravantti, J. (Participant), Huiskonen, J. (Participant), Jäälinoja, H. (Participant), Ora, A. (Participant), Hattula, K. (Participant), Ziedaite, G. (Participant), Romanovskaya, A. (Participant), Lisal, J. (Participant), Buivydas, A. (Participant), Redder, P. (Participant), Domanska, A. (Participant), Vilen, S. (Participant), Manole, V. (Participant), Happonen, L. (Participant), Seitsonen, J. (Participant), Liljeroos, L. (Participant), Suchanova, B. (Participant), Falck, S. (Participant), Daugelavicius, R. (Participant), Golubtsov, A. (Participant), Yuan, P. (Participant), Anastasina, M. (Participant), Karhu, N. J. (Participant), Koivunen, M. (Participant), Laurinavicius, S. (Participant), Wallin, A. (Participant), Aalto, A. P. (Participant), Sarin, P. (Participant), Atanasova, N. (Participant), Sun, X. (Participant), Pietilä, M. (Participant), Krupovic, M. (Participant), Cvirkaite-Krupovic, V. (Participant), Kukkaro, P. (Participant) & Pirttimaa, M. (Participant)
25/02/2011 → 31/12/2016
Project: Research Evaluation 2011
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Dynamin independent endocytosis is an alternative cell entry mechanism for multiple animal viruses
Ojha, R., Jiang, A., Mäntylä, E., Quirin, T., Modhira, N., Witte, R., Gaudin, A., De Zanetti, L., Gormal, R. S., Vihinen-Ranta, M., Mercer, J., Suomalainen, M., Greber, U. F., Yamauchi, Y., Lozach, P.-Y., Helenius, A., Vapalahti, O., Young, P., Watterson, D. & Meunier, F. A. & 2 others, , Nov 2024, In: PLoS Pathogens. 20, 11, 34 p., e1012690.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
The Replicase Protein of Potato Virus X Is Able to Recognize and Trans-Replicate Its RNA Component
Dutta, P., Lõhmus, A., Ahola, T. & Mäkinen, K., Oct 2024, In: Viruses. 16, 10, 15 p., 1611.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
Positive-strand RNA viruses-a Keystone Symposia report
Cable, J., Denison, M. R., Kielian, M., Jackson, W. T., Bartenschlager, R., Ahola, T., Mukhopadhyay, S., Fremont, D. H., Kuhn, R. J., Shannon, A., Frazier, M. N., Yuen, K.-Y., Coyne, C. B., Wolthers, K. C., Ming, G.-L., Guenther, C. S., Moshiri, J., Best, S. M., Schoggins, J. W. & Jurado, K. A. & 25 others, , Mar 2023, In: Annals of the New York Academy of Sciences. 1521, 1, p. 46-66 21 p.Research output: Contribution to journal › Article › Scientific › peer-review
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The infectivity of SARS-CoV-2 progeny virions requires the activity of host cell N-myristoyltransferases and it is severely compromised by their inhibition
Saber, H., Ojha, R. K., Quirin, T., Kant, R., Strandin, T., Kareinen, L., Yak, N., Sironen, T., Vapalahti, O., Balistreri, G. & Joensuu, M., 7 Mar 2023, In: bioRxiv.Research output: Contribution to journal › Article › Scientific
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Alphavirus RNA replication in vertebrate cells
Ahola, T., McInerney, G. M. & Merits, A., 2021, In: Advances in Virus Research. 111, p. 111-156Research output: Contribution to journal › Review Article › peer-review
Activities
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Chikungunya virus nonstructural protein 1 as an antiviral target - doctoral thesis of Kristina Kovacikova, Leiden University
Ahola, T. (Opponent)
20 Apr 2021Activity: Examination types › Opponent of doctoral dissertation
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Avian influenza virus infection in human innate immune cells - doctoral thesis of Veera Westenius, Aalto University
Ahola, T. (Opponent)
22 Mar 2019Activity: Examination types › Opponent of doctoral dissertation
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Antimicrobial Agents and Chemotherapy (Journal)
Ahola, T. (Member of editorial board)
2019 → 2021Activity: Publication peer-review and editorial work types › Editor of research journal
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Viruses (Basel) (Journal)
Ahola, T. (Editor)
2017 → 2018Activity: Publication peer-review and editorial work types › Editor of special theme number
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American Society for Virology 2017 Meeting
Pietilä, M. (Attendee)
24 Jun 2017 → 28 Jun 2017Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars