Projects per year
Organization profile
Organisation Profile
We aim towards deep understanding of RNA virus replication at the molecular level. Through the discovery of basic mechanistic principles, we develop new and general antiviral strategies.
International and National Collaboration
Publications and projects within past five years.
Profiles
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Tero Ahola
- Department of Microbiology - University Lecturer
- Helsinki One Health (HOH)
- RNA virus replication and antivirals
- Doctoral Programme in Drug Research - Supervisor for doctoral programme
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
- Doctoral Programme in Microbiology and Biotechnology - Supervisor for doctoral programme
Person: U3 Research and teaching staff, UH, Teaching and research personnel
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Sari Mattila
- Department of Microbiology - Postdoctoral Researcher
- RNA virus replication and antivirals
Person: U2 Teaching and research staff, UH
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Mohammadreza Sadeghi
- Department of Microbiology - Postdoctoral Researcher
- RNA virus replication and antivirals
Person: U2 Teaching and research staff
Projects
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Viral replication complexes: Virus replication machineries – Structure and function
Pietilä, M. & Pham, M. T.
01/01/2017 → …
Project: University of Helsinki Three-Year Research Project
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Center of Excellence in Virus Research (CoE_VIRRES)
Bamford, D., Bamford, J., Butcher, S., Oksanen, H. M., Poranen, M., Roine, E., Kainov, D., Tuma, R., Ravantti, J., Huiskonen, J., Jäälinoja, H., Ora, A., Hattula, K., Ziedaite, G., Romanovskaya, A., Lisal, J., Buivydas, A., Redder, P., Domanska, A., Vilen, S., Manole, V., Happonen, L., Seitsonen, J., Liljeroos, L., Suchanova, B., Falck, S., Daugelavicius, R., Golubtsov, A., Yuan, P., Anastasina, M., Karhu, N. J., Koivunen, M., Laurinavicius, S., Wallin, A., Aalto, A. P., Sarin, P., Atanasova, N., Sun, X., Pietilä, M., Krupovic, M., Cvirkaite-Krupovic, V., Kukkaro, P. & Pirttimaa, M.
25/02/2011 → …
Project: Research Evaluation 2011
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FUNREC: Functional reconstitution of membrane rearrangements induced by viral replication
Pietilä, M. & Lång, M.
01/09/2014 → 31/08/2017
Project: Research project
Publications
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Enzymatically synthesized 2'-fluoro-modified Dicer-substrate siRNA swarms against herpes simplex virus demonstrate enhanced antiviral efficacy and low cytotoxicity
Levanova, A., Kalke, K., Lund, L., Sipari, N., Sadeghi, M., Nyman, M., Paavilainen, H., Hukkanen, V. & Poranen, M., Oct 2020, In : Antiviral Research. 182, 8 p., 104916.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
A Highly Divergent Picornavirus Infecting the Gut Epithelia of Zebrafish (Danio rerio) in Research Institutions Worldwide
Altan, E., Kubiski, S. V., Boros, A., Reuter, G., Sadeghi, M., Deng, X., Creighton, E. K., Crim, M. J. & Delwart, E., Jun 2019, In : Zebrafish. 16, 3, p. 291-299 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Midbiotics: conjugative plasmids for genetic engineering of natural gut flora
Ruotsalainen, P., Penttinen, R., Mattila, S. & Jalasvuori, M., 2 Nov 2019, In : Gut Microbes. 10, 6, p. 643-653 11 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Newly detected DNA viruses in juvenile nasopharyngeal angiofibroma (JNA) and oral and oropharyngeal squamous cell carcinoma (OSCC/OPSCC)
Dickinson, A., Xu, M., Silen, S., Wang, Y., Fu, Y., Sadeghi, M., Toppinen, M., Carpen, T., Hedman, K., Mäkitie, A. & Söderlund-Venermo, M., Feb 2019, In : European Archives of Oto-Rhino-Laryngology. 276, 2, p. 613-617 5 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
New Phylogenetic Grouping of Positive-Sense RNA Viruses Is Concordant with Replication Complex Morphology
Ahola, T., 2019, In : mBio. 10, 4, 2 p., ARTN e01402-19.Research output: Contribution to journal › Letter › Scientific
Open AccessFile
Activities
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Avian influenza virus infection in human innate immune cells - doctoral thesis of Veera Westenius, Aalto University
Tero Ahola (Opponent)
22 Mar 2019Activity: Examination types › Opponent of doctoral dissertation
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Antimicrobial Agents and Chemotherapy (Journal)
Tero Ahola (Member of editorial board)
2019 → 2021Activity: Publication peer-review and editorial work types › Editor of research journal
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American Society for Virology 2017 Meeting
Maija Pietilä (Attendee)
24 Jun 2017 → 28 Jun 2017Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Viruses (Journal)
Tero Ahola (Editor)
2017 → 2018Activity: Publication peer-review and editorial work types › Editor of special theme number
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Docentship in Molecular Virology, Faculty of Biological and Environmental Sciences (External organisation)
Maija Pietilä (Assessment)
2016Activity: Membership types › Assessment of candidates for academic posts