STEMM - Stem Cells and Metabolism Research Program

Minna Ampuja
- minna.ampujahelsinkifi
- STEMM - Stem Cells and Metabolism Research Program - University Researcher
Person: U3 Research and teaching staff
20112025
Cesar Araujo
- cesar.l.araujohelsinkifi
- Hannes Tapani Lohi / Principal Investigator
Person
20072024
Meharji Arumilli
- Hannes Tapani Lohi / Principal Investigator
Person: UH
20122024
Diego Balboa
- diego.balboahelsinkifi
- Faculty Common Matters (Faculty of Medicine) - Title of Docent
- STEMM - Stem Cells and Metabolism Research Program - University Researcher
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
- Centre of Excellence in Stem Cell Metabolism
Person: U3 Research and teaching staff, UH
20132026
Rishi Banerjee
- rishi.banerjeehelsinkifi
- STEMM - Stem Cells and Metabolism Research Program - Postdoctoral Researcher
Person: U2 Teaching and research staff
20202024

Hannes Tapani Lohi / Principal Investigator
STEMM - Stem Cells and Metabolism Research Program
Organisational unit: Research group
Kidney development
STEMM - Stem Cells and Metabolism Research Program
Organisational unit: Research group
Kivelä Lab
STEMM - Stem Cells and Metabolism Research Program
Organisational unit: Research group
Raivio Group
STEMM - Stem Cells and Metabolism Research Program
Organisational unit: Research group

Helsinki Metabolomics Center (LS-RIA/ Metabo-HiLIFE)
Nieminen, A. I. (Manager) & Sipari, N. (Operator)
Faculty of Medicine
Facility/equipment: Core Facility

1 Not started
46 Active
50 Finished

Generation of kisspeptin neurons from hu
Raivio, T. (Project manager) & Gómez Sánchez, C. (Participant)
Novo Nordisk Fonden
01/01/2026 → 31/12/2028
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
Generation of kisspeptin neurons from human pluripotent stem cells
Raivio, T. (Project manager), Gómez Sánchez, C. (Participant) & Pulli, A. K. (Participant)
Academy of Finland
01/09/2025 → 31/08/2029
Project: Research Council of Finland: Academy Project
Lysosomal mechanisms modulating neural resilience in healthy aging
McWilliams, T. (Project manager)
Suomen Akatemia Talous/Paula Pesola
01/09/2025 → 31/08/2029
Project: Research Council of Finland: Academy Project
DWS 2025 Sami Jalil
Jalil, S. (Project manager)
Diabetes Wellness Suomi säätiö
01/09/2025 → 31/08/2026
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
Mary och Georg Ehrnrooths_Wartiovaara Ki
Wartiovaara, K. (Project manager)
Mary och Georg C. Ehrnrooths stiftelse sr
01/09/2025 → 31/08/2026
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)

Genetic Correction of the Most Common Mutation Causing Primary Hyperoxaluria Restores Enzyme Localization and Oxalate Metabolism
Keskinen, T., Jalil, S., Gümüşoğlu, I., Juutila, J., Kestilä, N., Kuuluvainen, E., Hietakangas, V., Balboa, D., Wartiovaara, K. & Hyvönen, M. E., Jan 2026, In: Journal of Inherited Metabolic Disease. 49, 1, 15 p., e70122.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
Integrated transcriptomic analysis reveals metabolic remodeling and gene expression networks related to human 8-cell-stage embryo-like cells
Paloviita, P., Nykänen, S., Harjuhaahto, S., Grym, H., Santaniemi, R., Tyynismaa, H., Torregrosa-Munumer, R. & Vuoristo, S., 27 Jan 2026, In: Cell Reports. 45, 1, 27 p., 116748.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
Killing of Human β-Cells by CD8+ T Cells Triggers Inflammatory Paracrine Signaling and Neighboring β-Cell Dysfunction
Oshima, M., Halliez, C., Kobaisi, F., Mode, N., Fouque, A., Brandao, B., Mayer, O., Balboa, D., Mallone, R. & Scharfmann, R., Jan 2026, In: Diabetes. 75, 1, p. 124-132 9 p.
Research output: Contribution to journal › Article › Scientific › peer-review
Lgi2-deficient mice manifest epileptiform activity in the developing hippocampal network and ADHD-like behavioural comorbidity in adulthood
Savonlehto, T., Nevalainen, E., Kukko-Lukjanov, T.-K., Hytönen, M. K., Seppälä, E., Segerstråle, M., Partanen, J., Lauri, S. E., Lohi, H. & Taira, T., Feb 2026, In: Experimental Neurology. 396, 11 p., 115541.
Research output: Contribution to journal › Article › Scientific › peer-review
2-hydroxyglutarate mediates whitening of brown adipocytes coupled to nuclear softening upon mitochondrial dysfunction
Kaul, H., Isermann, L., Senft, K., Popovic, M., Georgomanolis, T., Baumann, L., Sivanesan, P., Pouikli, A., Nolte, H., Lucic, B., Hildebrandt, X., Seidel, K., Gnad, T., Gaedke, F., Goebel, U., Peters, F., Cherevatenko, M., Park, J. H., Schauss, A. & Peltzer, N. & 8 others, Bruening, J. C., Kornfeld, J.-W., Pfeifer, A., Langer, T., Lusic, M., Wickström, S. A., Frezza, C. & Trifunovic, A., 1 Aug 2025, In: Nature metabolism. 7, 8, p. 1593-1613 38 p.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File

The Metabolomics in Life Science conference
Sipari, N. (Attendee)
30 Jan 2024 → 31 Jan 2024
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Dysregulation of neurofilament and Ca2+ signaling in Charcot-Marie-Tooth neuropathy
Ylikallio, E. (Speaker)
13 Dec 2024
Activity: Talk or presentation types › Invited talk
4th Scientific International Congress on SMA
Ylikallio, E. (Attendee)
14 Mar 2024 → 16 Mar 2024
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Perinnölliset metaboliset neuropatiat
Ylikallio, E. (Speaker)
19 Apr 2024
Activity: Talk or presentation types › Invited talk
Eksomisekvensointi tutkimusmenetelmänä Charcot-Marie-Tooth-sairauden diagnostiikassa
Ylikallio, E. (Supervisor)
2024
Activity: Examination types › Supervision of other thesis (Master's, Licentiate)

A.I.Virtanen Prize
Wickström, S. (Recipient), 15 Dec 2023
Prize: Prizes and awards
Anders Jahre Prize for Young Scientist
Suomalainen Wartiovaara, A. (Recipient), 2003
Prize: Prizes and awards
Animal Protection Award
Lohi, H. (Recipient), 2019
Prize: Prizes and awards
ASCB Innovation In Research Award
Wickström, S. (Recipient), 1 Dec 2023
Prize: Prizes and awards
Award of The Outstanding Young Person of Finland: Category of Medicine
Suomalainen Wartiovaara, A. (Recipient), 1995
Prize: Prizes and awards

Feline biobank
Lohi, H. (Creator), University of Helsinki, 2017
Dataset
Canine biobank
Lohi, H. (Creator), University of Helsinki, 2017
Dataset

What are the seven personality traits of cats and how do they vary by breed?
Lohi, H.
07/09/2021 → 01/10/2021
2 items of Media coverage
Press/Media: Press / Media
Cats have seven different personality and behavioral traits: Study
Lohi, H.
15/09/2021
1 item of Media coverage
Press/Media: Press / Media
Cats have 7 distinct personality and behavioral traits, researchers find
Lohi, H.
12/09/2021 → 13/09/2021
49 items of Media coverage
Press/Media: Press / Media
Finnish scientists identify seven character-defining traits in cats
Lohi, H.
13/09/2021
1 item of Media coverage
Press/Media: Press / Media
Some traits that define the character of cats
Lohi, H.
13/09/2021
1 item of Media coverage
Press/Media: Press / Media

STEMM - Stem Cells and Metabolism Research Program

Collaborations and top research areas from the last five years

Dive into details

Minna Ampuja

Cesar Araujo

Meharji Arumilli

Diego Balboa

Rishi Banerjee

Hannes Tapani Lohi / Principal Investigator

Kidney development

Kivelä Lab

Raivio Group

Helsinki Metabolomics Center (LS-RIA/ Metabo-HiLIFE)

Generation of kisspeptin neurons from hu

Generation of kisspeptin neurons from human pluripotent stem cells

Lysosomal mechanisms modulating neural resilience in healthy aging

DWS 2025 Sami Jalil

Mary och Georg Ehrnrooths_Wartiovaara Ki

Genetic Correction of the Most Common Mutation Causing Primary Hyperoxaluria Restores Enzyme Localization and Oxalate Metabolism

Integrated transcriptomic analysis reveals metabolic remodeling and gene expression networks related to human 8-cell-stage embryo-like cells

Killing of Human β-Cells by CD8+ T Cells Triggers Inflammatory Paracrine Signaling and Neighboring β-Cell Dysfunction

Lgi2-deficient mice manifest epileptiform activity in the developing hippocampal network and ADHD-like behavioural comorbidity in adulthood

2-hydroxyglutarate mediates whitening of brown adipocytes coupled to nuclear softening upon mitochondrial dysfunction

The Metabolomics in Life Science conference

Dysregulation of neurofilament and Ca2+ signaling in Charcot-Marie-Tooth neuropathy

4th Scientific International Congress on SMA

Perinnölliset metaboliset neuropatiat

Eksomisekvensointi tutkimusmenetelmänä Charcot-Marie-Tooth-sairauden diagnostiikassa

A.I.Virtanen Prize

Anders Jahre Prize for Young Scientist

Animal Protection Award

ASCB Innovation In Research Award

Award of The Outstanding Young Person of Finland: Category of Medicine

Feline biobank

Canine biobank

What are the seven personality traits of cats and how do they vary by breed?

Cats have seven different personality and behavioral traits: Study

Cats have 7 distinct personality and behavioral traits, researchers find

Finnish scientists identify seven character-defining traits in cats

Some traits that define the character of cats

STEMM - Stem Cells and Metabolism Research Program

Collaborations and top research areas from the last five years

Profiles

Research units

Equipment

Projects

Research output

Activities

Prizes

Datasets

Press/Media