Tracers in Molecular Imaging (TRIM)

  • PL 55 (A. I. Virtasen aukio 1)

    00014 HELSINGIN YLIOPISTO

    Finland

Publications 2007 2020

2019

Comparison of water phase diffusion experiments in laboratory and in situ conditions

Voutilainen, M., Kekäläinen, P., Poteri, A., Siitari-Kauppi, M., Helariutta, K., Andersson, P., Nilsson, K., Byegård, J., Skålberg, M., Yli-Kaila, M. & Koskinen, L., Aug 2019, In : Journal of Hydrology. 575, p. 716-729 14 p.

Research output: Contribution to journalArticleScientificpeer-review

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Electronic autoradiography of Ba-133 particle emissions; diffusion profiles in granitic rocks

Muuri, E., Sorokina, T., Donnard, J., Billon, S., Helariutta, K., Koskinen, L., Martin, A. & Siitari-Kauppi, M., Jul 2019, In : Applied Radiation and Isotopes. 149, p. 108-113 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Multimodality labeling strategies for the investigation of nanocrystalline cellulose biodistribution in a mouse model of breast cancer

Sarparanta, M., Pourat, J., Carnazza, K. E., Tang, J., Paknejad, N., Reiner, T., Kostiainen, M. A. & Lewis, J. S., 9 Nov 2019, (Accepted/In press) In : Nuclear Medicine and Biology.

Research output: Contribution to journalArticleScientificpeer-review

Porous Silicon as a Platform for Radiation Theranostics Together with a Novel RIB-Based Radiolanthanoid

Jakobsson, U., Mäkilä, E., Airaksinen, A. J., Alanen, O., Etile, A., Köster, U., Ranjan, S., Salonen, J., Santos, H. A. & Helariutta, K., 12 Mar 2019, In : Contrast Media & Molecular Imaging. 2019, 9 p., 3728563.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Production of a C-15 radioactive ion beam based on O-18(n, alpha)

Malkiewicz, T., Lhersonneau, G., Fadil, M., Jacobsson, U., Jones, P., Helariutta, K., Karvonen, P., Khlebnikov, S. & Trzaska, W. H., 7 Jun 2019, In : European Physical Journal. A, Hadrons and Nuclei. 55, 6, 8 p., 88.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Radiolabeled Molecular Imaging Probes for the in Vivo Evaluation of Cellulose Nanocrystals for Biomedical Applications

Imlimthan, S., Otaru, S., Keinänen, O., Correia, A., Lintinen, K., Almeida Santos, H., Airaksinen, A., Kostiainen, M. & Sarparanta, M., Feb 2019, In : Biomacromolecules. 20, 2, p. 674–683 10 p.

Research output: Contribution to journalArticleScientificpeer-review

The Radiopharmaceutical Chemistry of Fluorine-18: Next-Generation Fluorinations

Airaksinen, A., 2019, Radiopharmaceutical Chemistry. Lewis, J. S., Windhorst, A. D. & Zeglis, B. M. (eds.). Cham: Springer International Publishing AG, p. 297-310 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapterScientific

2018

Abscopal Effect in Non-injected Tumors Achieved with Cytokine-Armed Oncolytic Adenovirus

Havunen, R., Santos, J. M., Sorsa, S., Rantapero, T., Lumen, D., Siurala, M., Airaksinen, A. J., Cervera-Carrascon, V., Tähtinen, S., Kanerva, A. & Hemminki, A., 21 Dec 2018, In : Molecular Therapy - Oncolytics. 11, p. 109-121 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Carbon monoxide releasing molecule improves structural and functional cardiac recovery after myocardial injury

Segersvärd, H., Lakkisto, P., Hänninen, M., Forsten, H., Siren, J., Immonen, K., Kosonen, R., Sarparanta, M., Laine, M. & Tikkanen, I., 5 Jan 2018, In : European Journal of Pharmacology. 818, p. 57-66 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Delivery of Agents Into Articular Cartilage With Electric Spark-Induced Sound Waves

Pérez, A. G., Nieminen, H. J., Finnilä, M., Salmi, A., Pritzker, K. P. H., Lampsijärvi, E., Paulin, T., Airaksinen, A. J., Saarakkala, S. & Haeggström, E., 16 Oct 2018, In : Frontiers in Physics. 6, 7 p., 116.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Efficient cartridge purification for producing high molar activity [18F]fluoro-glycoconjugates via oxime formation

Keinänen, O., Partelová, D., Alanen, O., Antopolsky, M., Sarparanta, M. & Airaksinen, A. J., 2018, In : Nuclear Medicine and Biology. 67, p. 27-35 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Multimodality Imaging of Silica and Silicon Materials In Vivo

Şen, K. D., P., S. M., M., R. J. & J., A. A., 13 Jun 2018, In : Advanced Materials. 30, 24, 26 p., 1703651.

Research output: Contribution to journalReview ArticleScientificpeer-review

The First Matrix Diffusion Experiment in the Water Phase of the REPRO Project: WPDE 1

Poteri, A., Andersson, P., Nilsson, K., Johan, B., Skålberg, M., Siitari-Kauppi, M. K., Helariutta, A. M. K., Voutilainen, M. A., Kekäläinen, P. J., Ikonen, J. O., Sammaljärvi, J. K. W., Antero, L., Timonen, J., Kuva, J. & Koskinen, L., 2018, Olkiluoto, Eurajoki: Posiva. 288 p. (Posiva Working Report; no. 2017-23)

Research output: Book/ReportCommissioned report

Open Access

The Second Matrix Diffusion Experiment in the Water Phase of the Repro Project: WPDE 2

Poteri, A., Andersson, P., Nilsson, K., Byegård, J., Skålberg, M., Siitari-Kauppi, M. K., Helariutta, A. M. K., Voutilainen, M. A. & Kekäläinen, P. J., 2018, Olkiluoto, Eurajoki: Posiva. 143 p. (Posiva Working Report; no. 2017-24)

Research output: Book/ReportCommissioned report

Open Access
2017

Comparison of 68Ga-DOTA-Siglec-9 and 18F-Fluorodeoxyribose-Siglec-9: Inflammation Imaging and Radiation Dosimetry

Virtanen, H., Silvola, J. M. U., Autio, A., Li, X-G., Liljenback, H., Hellberg, S., Siitonen, R., Ståhle, M., Käkelä, M., Airaksinen, A. J., Helariutta, K., Tolvanen, T., Veres, T. Z., Saraste, A., Knuuti, J., Jalkanen, S. & Roivainen, A., 2017, In : Contrast Media & Molecular Imaging. p. 1-10 10 p., 7645070.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Drug-loaded Multifunctional Nanoparticles Targeted to the Endocardial Layer of the Injured Heart Modulate Hypertrophic Signaling

Ferreira, M. P. A., Ranjan, S., Kinnunen, S., Correia, A., Talman, V., Mäkilä, E., Barrios-Lopez, B., Kemell, M., Balasubramanian, V., Salonen, J., Hirvonen, J., Ruskoaho, H., Airaksinen, A. J. & Santos, H. A., 6 Sep 2017, In : Small. 13, 33, 14 p., 1701276.

Research output: Contribution to journalArticleScientificpeer-review

Novel Positron-Emitting Radiopharmaceuticals

Sarparanta, M. P., Demoin, D. W., Cook, B. E., Lewis, J. S. & Zeglis, B. M., 2017, Nuclear Oncology: From Pathophysiology to Clinical Applications. 2 ed. Chamonix, Sveitsi: Springer International Publishing AG, Vol. 2017. p. 129-171

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Open Access

Pretargeted PET Imaging of trans-Cyclooctene-Modified Porous Silicon Nanoparticles

Keinänen, O., Mäkilä, E. M., Lindgren, R., Virtanen, H., Liljenbäck, H., Oikonen, V., Sarparanta, M., Molthoff, C., Windhorst, A. D., Roivainen, A., Salonen, J. J. & Airaksinen, A. J., 31 Jan 2017, In : ACS Omega. 2, 1, p. 62-69 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Pretargeting of internalizing trastuzumab and cetuximab with a 18F-tetrazine tracer in xenograft models

Keinänen, O., Fung, K. E., Pourat, J., Jallinoja, V., Vivier, D., Pillarsetty, N. K., Airaksinen, A., Lewis, J. S., Zeglis, B. M. & Sarparanta, M., 2 Dec 2017, In : EJNMMI Research. 2017, 7, 12 p., 95.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Theranostic Imaging with Porous Silicon

Airaksinen, A., 2017, Handbook of Porous Silicon. Canham, L. (ed.). Continuously updated edition ed. Cham: Springer International Publishing , 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

2016

Adenoviral Delivery of Tumor Necrosis Factor-alpha and Interleukin-2 Enables Successful Adoptive Cell Therapy of Immunosuppressive Melanoma

Siurala, M., Havunen, R., Saha, D., Lumen, D., Airaksinen, A. J., Tähtinen, S., Cervera-Carrascon, V., Bramante, S., Parviainen, S., Vaha-Koskela, M., Kanerva, A. & Hemminki, A., Aug 2016, In : Molecular therapy. 24, 8, p. 1435-1443 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

A New Highly Reactive and Low Lipophilicity Fluorine-18 Labeled Tetrazine Derivative for Pretargeted PET Imaging

Keinänen, O., Li, X-G., Chenna, N. K., Lumen, D., Ott, J., Molthoff, C. F. M., Sarparanta, M., Helariutta, K., Vuorinen, T., Windhorst, A. D. & Airaksinen, A. J., Jan 2016, In : ACS Medicinal Chemistry Letters. 7, 1, p. 62-66 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Collective 2(1)(+) excitations in Po-206 and Rn-208,Rn-210

Grahn, T., Pakarinen, J., Jokiniemi, L., Albers, M., Auranen, K., Bauer, C., Bernards, C., Blazhev, A., Butler, P. A., Bönig, S., Damyanova, A., De Coster, T., De Witte, H., Elseviers, J., Gaffney, L. P., Huyse, M., Herzán, A., Jakobsson, U., Julin, R., Kesteloot, N. & 31 others, Konki, J., Kröll, T., Lewandowski, L., Moschner, K., Peura, P., Pfeiffer, M., Radeck, D., Rahkila, P., Rapisarda, E., Reiter, P., Reynders, K., Rudiger, M., Salsac, M. -D., Sambi, S., Scheck, M., Seidlitz, M., Siebeck, B., Steinbach, T., Stolze, S., Suhonen, J., Thoele, P., Thürauf, M., Warr, N., Van Duppen, P., Venhart, M., Vermeulen, M. J., Werner, V., Veselsky, M., Vogt, A., Wrzosek-Lipska, K. & Zieliska, M., Nov 2016, In : European Physical Journal. A, Hadrons and Nuclei. 52, 11, 8 p., 340.

Research output: Contribution to journalArticleScientificpeer-review

Comparison of somatostatin receptor 2-targeting PET tracers in the detection of mouse atherosclerotic plaques.

Petteri, R., Hellberg, S., Kiugel, M., Virta, J., Li, X-G., Käkelä, M., Helariutta, K., Luoto, P., Liljenbäck, H., Hakovirta, H., Gardberg, M., Airaksinen, A. J., Knuuti, J., Saraste, A. & Roivainen, A., Feb 2016, In : Molecular Imaging and Biology. 18, 1, p. 99-108 10 p.

Research output: Contribution to journalArticleScientificpeer-review

In Vitro and In Vivo Assessment of Heart-Homing Porous Silicon Nanoparticles

Almeida Ferreira, M. P., Ranjan, S., Correia, A., Mäkilä, E., Kinnunen, S. M., Zhang, H., Shahbazi, M-A., Vingadas Almeida, P., Salonen, J., Ruskoaho, H. J., Airaksinen, A., Hirvonen, J. T. & Almeida Santos, H., Jul 2016, In : Biomaterials. 94, p. 93–104 12 p.

Research output: Contribution to journalArticleScientificpeer-review

MICROLOCALIZED TRANSPORT OF AGENTS INTO ARTICULAR CARTILAGE USING HIGH INTENSITY ULTRASOUND

Nieminen, H. J., Lampsijarvi, E., Salmi, A., Airaksinen, A., Saarakkala, S., Pritzker, K. P. & Haeggstrom, E., Apr 2016, p. S522-S523. 2 p.

Research output: Conference materialsAbstract

2015

Adenovirus Improves the Efficacy of Adoptive T-cell Therapy by Recruiting Immune Cells to and Promoting Their Activity at the Tumor

Tähtinen, S., Gronberg-Vähä-Koskela, S., Lumen, D., Merisalo-Soikkeli, M., Siurala, M., Airaksinen, A. J., Vähä-Koskela, M. & Hemminki, A., Aug 2015, In : Cancer immunology research. 3, 8, p. 915-925 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Cooperation in education and training in nuclear- and radiochemistry in Europe

John, J., Lehto, J., Koivula, T. & Omtvedt, J. P., Apr 2015, In : Journal of Radioanalytical and Nuclear Chemistry. 304, 1, p. 459-466 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Formation of Heavy Neutron-Deficient Nuclides in 3He-Induced Reactions

Aaltonen, J., Gromova, E. A., Jakovlev, V. A., Helariutta, K., Maltsev, N. A., Penttilä, H., Rubchenya, V. A., Trzaska, W. H. & Salminen-Paatero, S., Jul 2015, In : Russian Academy of Sciences. Bulletin. Physics. 79, 7, p. 848-851 4 p.

Research output: Contribution to journalArticleScientificpeer-review

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Measurement of H-3, Cl-36, Na-22, Sr-85 and Ba-133 activities from synthetic groundwater

Qian, L., Helariutta, K., Ikonen, J., Siitari-Kauppi, M., Voutilainen, M. & Koskinen, L., Oct 2015, In : Journal of Radioanalytical and Nuclear Chemistry. 306, 1, p. 131-137 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Multifunctional porous silicon nanoparticles for cancer theranostics

Wang, C-F., Sarparanta, M. P., Mäkilä, E. M., Hyvönen, M. L. K., Laakkonen, P. M., Salonen, J. J., Hirvonen, J. T., Airaksinen, A. J. & Santos, H. A., Apr 2015, In : Biomaterials. 48, p. 108-118 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Oxidative Stress Protection by Exogenous Delivery of rhHsp70 Chaperone to the Retinal Pigment Epithelium (RPE), a Possible Therapeutic Strategy Against RPE Degeneration

Subrizi, A., Toropainen, E., Ramsay, E., Airaksinen, A. J., Kaarniranta, K. & Urtti, A., Jan 2015, In : Pharmaceutical Research. 32, 1, p. 211-221 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Synthesis, in vitro and in vivo evaluation of 1,3,5-triazines as cannabinoid CB2 receptor agonists

Yrjölä, S., Sarparanta, M., Airaksinen, A. J., Hytti, M., Kauppinen, A., Pasonen-Seppanen, S., Adinolfi, B., Nieri, P., Manera, C., Keinanen, O., Poso, A., Nevalainen, T. J. & Parkkari, T., 25 Jan 2015, In : European Journal of Pharmaceutical Sciences. 67, p. 85-96 12 p.

Research output: Contribution to journalArticleScientificpeer-review

2014

Copper-free azide-alkyne cycloaddition of targeting peptides to porous silicon nanoparticles for intracellular drug uptake

Wang, C-F., Mäkilä, E. M., Kaasalainen, M. H., Liu, D., Sarparanta, M. P., Airaksinen, A. J., Salonen, J. J., Hirvonen, J. T. & Santos, H. A., Jan 2014, In : Biomaterials. 35, 4, p. 1257-1266 10 p.

Research output: Contribution to journalArticleScientificpeer-review

In Vivo Evaluation of Porous Silicon and Porous Silicon Solid Lipid Nanocomposites for Passive Targeting and Imaging

Kallinen, A. M., Sarparanta, M. P., Liu, D., Makila, E. M., Salonen, J. J., Hirvonen, J. T., Santos, H. A. & Airaksinen, A. J., Aug 2014, In : Molecular Pharmaceutics. 11, 8, p. 2876-2886 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Porous silicon nanoparticles for nanomedicine: preparation and biomedical applications

Santos, H. A., Mäkilä, E., Airaksinen, A., Bimbo, L. M. & Hirvonen, J., 2014, In : Nanomedicine. 9, 4, p. 535-554 20 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Radiolabeled porous silicon for bioimaging applications

Airaksinen, A., 2014, Porous silicon for biomedical applications. Santos, H. (ed.). Woodhead publishing, p. 253-269 17 p. (Woodhead Publishing Series in Biomaterials; no. 68).

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Study of Proton and He-3 Induced Reactions on U-235 at Low Energies

Gromova, E., Jakovlev, V., Aaltonen, J., Helariutta, K., Salminen-Paatero, S., Bergman, J., Heselius, S. -J., Penttilä, H., Rissanen, J. & Saastamoinen, A., May 2014, In : Nuclear Data Sheets. 119, p. 237-240 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Synthesis and biological evaluation of novel I-123-labeled 4-(4-iodophenyl)butanoyl-L-prolyl-(2S)-pyrrolidines for imaging prolyl oligopeptidase in vivo

Kallinen, A., Todorov, B., Kallionpää, R., Back, S., Sarparanta, M., Raki, M., Garcia-Horsman, J. A., Bergstrom, K. A., Wallen, E. A. A., Mannisto, P. T. & Airaksinen, A. J., 22 May 2014, In : European Journal of Medicinal Chemistry. 79, p. 436-445 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Using 5-deoxy-5-[F-18] fluororibose to glycosylate peptides for positron emission tomography

Li, X-G., Helariutta, K., Roivainen, A., Jalkanen, S., Knuuti, J. & Airaksinen, A. J., Jan 2014, In : Nature Protocols. 9, 1, p. 138-145 8 p.

Research output: Contribution to journalArticleScientificpeer-review

2013
Open Access

Evaluation of the Physicochemical and Biopharmaceutical properties of Fluoro-Indomethacin

Mori, M. M., Airaksinen, A. J., Hirvonen, J. T., A. Santos, H. & Caramella, C. M., 2013, In : Current Drug Metabolism. 14, 1, p. 80-89 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Migration kinetics of ion-implanted beryllium in ZnO and GaN

Koskelo, O., Köster, U., Tuomisto, F., Helariutta, K., Sopanen, M., Suihkonen, S., Svensk, O. & Räisänen, J., Sep 2013, In : Physica Scripta. 88, 3, p. 035603 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Radiosynthesis and evaluation of new alpha(1)-adrenoceptor antagonists as PET radioligands for brain imaging

Airaksinen, A. J., Finnema, S. J., Balle, T., Varnäs, K., Bang-Andersen, B., Gulyas, B., Farde, L. & Halldin, C., Aug 2013, In : Nuclear Medicine and Biology. 40, 6, p. 747-754 8 p.

Research output: Contribution to journalArticleScientificpeer-review

SPECT/CT imaging of radiolabeled cubosomes and hexosomes for potential theranostic applications

Nilsson, C., Barrios-Lopez, B., Kallinen, A., Laurinmäki, P., Butcher, S. J., Raki, M., Weisell, J., Bergström, K., Larsen, S. W., Ostergaard, J., Larsen, C., Urtti, A., Airaksinen, A. J. & Yaghmur, A., Nov 2013, In : Biomaterials. 34, 33, p. 8491-8503 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Stable and selective scintillating anion-exchange sensors for quantification of 99TcO4- in natural freshwaters

Seliman, A. F., Helariutta, K., Wiktorowicz, S. J., Tenhu, H. & Harjula, R., Dec 2013, In : Journal of Environmental Radioactivity. 126, p. 156-164 9 p.

Research output: Contribution to journalArticleScientificpeer-review