University of Helsinki

  • Helsinki

    Finland

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2020

Bitopic and Peripheral Membrane Proteins as Drug Targets: Broader Biophysical Insight from Biomembrane Simulations that Transcends the "Lock and Key'' Paradigm

Bunker, A., 7 Feb 2020, In : Biophysical Journal. 118, 3, p. 160A-160A 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Interaction of Benzothiazole Dye Thioflavin T with Acidic Protein Prothymosin Alpha

Antifeeva, I. A., Fonin, A. V., Sulatskaya, A. I., Karasev, M. M., Kuznetsova, I. M. & Turoverov, K. K., 7 Feb 2020, In : Biophysical Journal. 118, 3, p. 372A-373A 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

MicroRNA-193a family as potential clinical biomarker and therapeutic agent in advanced Melanoma

Carpi, S., Polini, B., Ylösmäki, L., Ylösmäki, E., Cerullo, V., Romanini, A. & Nieri, P., 11 Feb 2020, In : Journal of Translational Medicine. 18, Supplement 1, 1 p., 25.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Postereita ja teknopuhetta Aleksanteri-konferenssissa 2019

Absetz, M. C., Reynolds, B., Gorbacheva, E., Heikkinen, J. K., Pylsy, M. & Ratilainen, S., 14 Apr 2020, In : Idäntutkimus. 27, 1, p. 88-91 4 p.

Research output: Contribution to journalMeeting AbstractResearch

Regioselective Prenylation of Peptide Termini during the Biosynthesis of the Natural Product Muscoride

Mattila, A., Andsten, R-M., Jumppanen, M., Assante, M., Jokela, J., Wahlsten, M., Mikula, K. M., Gugger, M., Koskela, H., Sivonen, K., Yli-Kauhaluoma, J., Iwai, H. & Fewer, D. P., Jan 2020, In : Marine Drugs. 18, 1, 1 p., 40.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2019

Activation of pro-survival signaling inhibits alpha-synuclein aggregation in dopaminergic neurons

Konovalova, J., Chmielarz, P., Er, S. & Domanskyi, A., Jul 2019, In : FEBS open bio. 9, p. 228-228 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Activation of RET tyrosine kinase prevents accumulation of misfolded alpha-synuclein induced by exogenous preformed fibrils

Chmielarz, P., Er, S., Banders, L., Alberts, K., Airavaara, M., Konovalova, J. & Domanskyi, A., Jul 2019, In : FEBS open bio. 9, p. 41-41 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

A phylogenetic comparison of Afrotropical Geometridae and their host-plants.

Staude, H. S., Sihvonen, P. & Hausmann, A., 2019, In : Spixiana. 42, 2, p. 303 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

A potent partial agonist of PKC orients in membranes like the biological activator diacylglycerol

Lautala, S., Koivuniemi, A., Kulig, W., Rog, T., Talman, V., Tuominen, R. & Bunker, A., Jul 2019, In : European Biophysics Journal. 48, p. S122-S122 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access
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Association between the arrested decline in cardiovascular disease and health and social-care costs: a modelling study

Collins, B., Bandosz, P., Guzman-Castillo, M., Pearson-Stuttard, J., Stoye, G., McCauley, J., Ahmadi-Abhari, S., Shipley, M. J., Araghi, M., Capewell, S., French, E., Brunner, E. J. & O'Flaherty, M., Nov 2019, In : Lancet. 394, Supplement 2, p. 33-33 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Associations between Microrna Expression, Disease Progression and Ex Vivo Drug Response in Multiple Myeloma

Kumari, R., Kumar, A., Parsons, A., Suvela, M., Lievonen, J., Silvennoinen, R., Anttila, P. & Heckman, C., 2019, In : Blood. 134, Supplement_1, 3069.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

Asthma is still a risk factor for mortality in Sweden and Norway ̣— the Nordic EpiLung Study

Backman, H., Bhatta, L., Hedman, L., Brumpton, B., Vähätalo, I., Lassman-Klee, P. G., Nwaru, B. I., Mai, X-M., Vikjord, S. A., Lindberg, A., Lundbäck, B., Rönmark, E. & Langhammer, A., 2019, In : European Respiratory Journal. 54, PA2778.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Azulene-based compounds targeting orexin receptors

Leino, T., Turku, A., Yli-Kauhaluoma, J., Kukkonen, J., Xhaard, H. & Wallen, E., 31 Mar 2019, In : Abstracts of papers of the American Chemical Society . 257, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Brain metabolome during anesthesia - similarities and differences between post-ictal state

Kohtala, S., Kärkkäinen, O. & Rantamäki, T., 2019, In : European Neuropsychopharmacology. 29, p. S645-S646 2 p.

Research output: Contribution to journalMeeting AbstractResearch

Brain region-dependent variation in myelin-related gene expression and myelin thickness in chronic psychosocial stress

Laine, M. A., Trontti, K., Misiewicz, Z., Sokolowska, E., Kulesskaya, N., Heikkinen, A., Saarnio, S., Balcells, I., Ameslon, P., Greco, D., Mattila, P., Ellonen, P., Paulin, L., Auvinen, P., Jokitalo, E. & Hovatta, I., Jul 2019, In : Glia. 67, p. E450-E451 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Characterization and tissue localization of ocular carboxylesterases in multiple species

Hammid, A., Vellonen, K-S., Ruponen, M., Urtti, A. & Honkakoski, P., Dec 2019, In : Acta Ophthalmologica. 97, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Characterization Of Focal And Generalized Epilepsy Polygenic Burden In 630,603 Individuals

Epi-Twenty-Five Consortium, Nov 2019, In : Epilepsia. 60, p. 27-28 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Children's food intake in relation to preschool-level facilitators and barriers of healthy nutrition

Lehto, R., Ray, C., Vepsalainen, H., Korkalo, L., Nissinen, K., Koivusilta, L., Roos, E. & Erkkola, M., Nov 2019, In : European Journal of Public Health. 29, Supplement: 4, p. 145-145 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Clinical implementation of precision systems oncology in the treatment of ovarian cancer based on ex-vivo drug testing and molecular profiling

Murumagi, A., Ungureanu, D., Khan, S., Hirasawa, A., Arjama, M., Valimaki, K., Mikkonen, P., Niininen, W., Kumar, A., Eldfors, S., Pellinen, T., Pietiainen, V., Magi, A., Koivisto-Korander, R., Tapper, J., Loukovaara, M., Aittokallio, T., Butzow, R. & Kallioniemi, O., Jul 2019, In : Cancer Research. 79, 13, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Combination effects of essential oils with antimicrobials

Stalnacke, M., Mgbeahuruike, E. & Holm, Y., Dec 2019, In : Planta Medica. 85, 18, p. 1523-1523 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Conductive 3D printed structures based on nanocellulose for electro-responsiveness and controlled drug release

Ajdary, R., Ezazi, N. Z., Huan, S., Santos, H. & Rojas, O., 31 Mar 2019, In : Abstracts of papers of the American Chemical Society . 257, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Developmental and cognitive profile of children with intestinal failure

Gunnar, R., Kanerva, K., Salmi, S., Hayrinen, T., Haataja, L., Pakarinen, M. & Merras-Salmio, L., Jul 2019, In : Transplantation. 103, p. S29-S30 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Differences of FENO in adult general populations of Nordic regions

Lassmann-Klee, P., Brumpton, B., Henriksen, A. H., Larsson, M., Sundblad, B-M., Põlluste, J., Lindqvist, A., Hedman, L., Backman, H., Rönmark, E., Langhammer, A., Piirilä, P. & Sovijärvi, A. R. A., 28 Sep 2019, In : European Respiratory Journal. 54, Suppl. 63, p. PA5064

Research output: Contribution to journalMeeting AbstractResearch

Doxorubicin-Induced Cardiotoxicity and Novel GATA4-Targeted Compounds

Karhu, T., Kinnunen, S., Talman, V. & Ruskoaho, H., 2 Aug 2019, In : Circulation Research. 125, A781, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Drug screening and molecular profiling identifies INKA1 as a predictive biomarker for sensitivity to MAPK inhibition-antimitotic combination treatment in pancreatic ductal adenocarcinoma

Gautam, P., Vaha-Koskela, M., Tomlinson, M., Cox, A. D., Der, C. J., Aittokallio, T. & Wennerberg, K., Dec 2019, In : Molecular Cancer Therapeutics. 18, 12 suppl., 2 p., A137.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Effect of Donor Simvastatin Treatment on Gene Expression Profiles in Human Cardiac Allografts during Ischemia-Reperfusion Injury

Krebs, R., Kankainen, M., Holmström, E., Dhaygude, K., Lukac, J., Ojala, T., Mattila, P., Nykänen, A. & Lemström, K., Apr 2019, In : Journal of Heart and Lung Transplantation. 38, 4, Supplement, p. S75-S76 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access
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Elevated circulating activin A levels in malignant pleural mesothelioma patients are related to cancer cachexia and poor response to platinum-based chemotherapy

Paajanen, J., Ilonen, I., Lauri, H., Jarvinen, T., Sutinen, E., Ollila, H., Rouvinen, E., Lemstrom, K., Rasanen, J., Ritvos, O., Koli, K. & Myllarniemi, M., 28 Sep 2019, In : European Respiratory Journal. 54, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

EVALUATION OF SAFE MEDICATION USE AMONG HOME CARE AND NURSING FACILITIES OLDER PATIENTS IN ESTONIA AND FINLAND

Bobrova, V., Baburina, U., Heinamaki, J., Honkanen, O., Desselle, S., Airaksinen, M. & Volmer, D., Dec 2019, In : Research in Social and Administrative Pharmacy. 15, 12, p. E47-E47 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Exploring and Reconstructing Ancestral Anatomies using Ontology-Informed Approaches

Tarasov, S., Miko, I., Yoder, M. & Uyeda, J., 2019, In : Biodiversity Information Science and Standards. 3, 1 p., e37038.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access
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GENETICS OF HUMAN PLASMA LIPIDOME AND ITS LINK TO DISEASES SUSCEPTIBILITY

SK Serv, T FinnGen Project, Tabassum, R., Rämö, J. T., Ripatti, P., Koskela, J. T., Kurki, M., Karjalainen, J., Palta, P., Hassan, S., Nunez-Fontarnau, J., Kiiskinen, T. T. J., Soderlund, S., Matikainen, N., Laivuori, H., Havulinna, A. S., Salomaa, V., Pirinen, M., Jauhiainen, M., Daly, M. J. & 3 others, Palotie, A., Taskinen, M. R. & Ripatti, S., Aug 2019, In : Atherosclerosis. 287, p. E14-E15 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

GENETICS OF VACCINATION RELATED NARCOLEPSY

Ollila, H., Wennerstrom, A., Partinen, M., Mignot, E., Saarela, J., Saavalainen, P., Vaarala, O., Tienari, P. & Perola, M., 2019, In : European Neuropsychopharmacology. 29, p. S994-S994 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

GENOME-WIDE ASSOCIATION STUDY OF SCHOOL GRADES INFORMS COGNITIVE GENETIC ARCHITECTURE OF SIX MAJOR PSYCHIATRIC DISORDERS

iPSYCH-Broad Consortium, 2019, In : European Neuropsychopharmacology. 29, p. 1103-1104 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Identification of C. elegans lipid lowering constituents form chaga by correlation of H-1 NMR spectra with phenotypic screening

Kirchweger, B., Kapp, K., Grienke, U., Lehner, T., Zwirchmayr, J., Tahir, A. & Rollinger, J. M., Dec 2019, In : Planta Medica. 85, 18, p. 1395-1395 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Induced and primed defence responses of Fragaria vesca against grey mold

Badmi, R., Zhang, Y., Tengs, T., Brurberg, M. B., Krokene, P., Fossdal, C. G., Hytonen, T. & Thorstensen, T., Oct 2019, In : Molecular Plant - Microbe Interactions. 32, 10, p. S1.9 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Injury Severity and Extracranial Injuries Are Associated with Delayed Return to Work in Mild Traumatic Brain Injury Patients

Huovinen, A., Isokuortti, H., Marinkovic, I., Vanni, S. & Melkas, S., 2 May 2019, In : Brain Injury. 33, p. 128-129 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

In situ detection of DNA double strand breaks by immunofluorescent gamma-H2AX staining in mice exposed to multiwalled carbon nanotubes

Aimonen, K., Huumonen, K., Savukoski, S., Lindberg, H., Schoonenberg, A., Valimaki, K., Libertini, S., Wolff, H., Catalan, J. & Norppa, H., 15 Oct 2019, In : Toxicology Letters. 314, p. S122-S122 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Intracranial Traumatic Lesions Delay Return to Work in Mild Traumatic Injury Patients

Huovinen, A., Marinkovic, I., Isokuortti, H., Korvenoja, A., Vanni, S. & Melkas, S., 2 May 2019, In : Brain Injury. 33, p. 130-131 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Label-Free Proteomics Approach Characterizes Plasma Protein Signature of Donor Brain Death

Lukac, J., Saraswat, M., Holmström, E., Dhaygude, K., Joenväärä, S., Krebs, R., Nykänen, A., Renkonen, R. & Lemström, K., Apr 2019, In : Journal of Heart and Lung Transplantation. 38, 4, Supplement, p. S159 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access
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L-LEUCINE COATED INHALABLE TEICOPLANIN POWDERS PRODUCED BY AEROSOL FLOW REACTOR METHOD

Ugur, N., Bimbo, L. M., Saris, P., Vartiainen, V., Hirvonen, J., Kauppinen, E. I. & Raula, J., 1 Jun 2019, In : Journal of Aerosol Medicine and Pulmonary Drug Delivery. 32, 3, p. A18-A19 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

LP(A)-DEPENDENT INFLAMMASOME ACTIVATION AS A DRIVER OF ITS ATHEROGENICITY

Oorni, K., Lorey, M. B., Borelli, M., Tigistu-Sahle, F., Ruuth, M., Aikas, L., Kakela, R., Boffa, M. B. & Koschinsky, M. L., Aug 2019, In : Atherosclerosis. 287, p. E282-E282 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Maternal iron supplementation in pregnancy and asthma in the offspring: follow-up of a randomised trial

Shaheen, S., Gissler, M., Devereux, G., Erkkola, M., Mcardle, H., Sheikh, A. & Nwaruz, B., 28 Sep 2019, In : European Respiratory Journal. 54, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Mice with selective loss of noradrenergic neurons as a potential novel model to study presymptomatic phase of Parkinson's disease

Barut, J., Jurga, A., Rafa-Zablocka, K., Baginska, M., Parlato, R., Domanskyi, A., Nalepa, I. & Krainer, G., Jul 2019, In : FEBS open bio. 9, p. 231-231 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Molecular phylogeny of New World geometrid moths (Lepidoptera, Geometridae)

Brehm, G., Murillo-Ramos, L., Sihvonen, P., Bodner, F., Bolt, D., Schmidt, C., Moser, A., Hausmann, A., Õunap, E., Viidalepp, J., Lindt, A., Parra, L. E., Tammaru, T. & Wahlberg, N., 2019, In : Spixiana. 42, 2, p. 303 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Multivariate GWAS of inflammatory markers reveals novel disease associations

Ruotsalainen, S. E., Partanen, J., Surakka, I., Pirinen, M., Salomaa, V., Salmi, M., Jalkanen, S., Daly, M. J., Ripatti, S. & Koskela, J., 10 Oct 2019, In : European Journal of Human Genetics. 27, 11, p. 1156-1157 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

NEEDS FOR, AND EXPECTATIONS OF, A POSTGRADUATE PHARMACY PROGRAM

Niittynen, I., Linden-Lahti, C. & Laaksonen, R., Dec 2019, In : Research in Social and Administrative Pharmacy. 15, 12, p. E51-E51 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Notebook: Customizable web forms for recording observations

Raitio, O. A., Juslén, A., Sirkiä, P., Lehikoinen, A., Tähtinen, M., Piirainen, E. & Riihikoski, V-M., 20 Aug 2019, In : Biodiversity Information Science and Standards. 3, 3 p., e39150.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access
File

Ocular melanin binding of drugs: in vitro binding studies

Bahrpeyma, S., Rimpelä, A-K., Hagström, M. & Urtti, A., Dec 2019, In : Acta Ophthalmologica. 97, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Pluripotent stem cells differentiation towards definitive endoderm

Bogacheva, M., Kanninen, L. & Lou, Y-R., 15 Oct 2019, In : Toxicology Letters. 314, p. S186-S187 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

POLYGENIC HYPERLIPIDEMIA INCREASES CORONARY ARTERY DISEASE RISK IN THE UK BIOBANK

Ripatti, P., Ramo, J. T., Soderlund, S., Surakka, I., Havulinna, A. S., Widen, E., Palta, P., Freimer, N. B., Salomaa, V., Pirinen, M., Palotie, A., Taskinen, M. R. & Ripatti, S., Aug 2019, In : Atherosclerosis. 287, p. E92-E92 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Pre-hospital thrombolysis of high-risk pulmonary embolism-patient characteristics, management and outcome

Harjola, J., Holmström, P., Kuisma, M. & Harjola, V-P., May 2019, In : European Journal of Heart Failure. 21, p. 131-132 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review