Viral Zoonosis Research Unit

Publications 2006 2019

2019

Arbovirusuhkat muuttuvassa ympäristössä

Kakkola, L., Huhtamo, E. & Vapalahti, O., 2019, In : Moodi.. 43, 1, p. 10-13 4 p.

Research output: Contribution to journalArticleProfessional

Bombali Virus in Mops condylurus Bat, Kenya

Forbes, K. M., Webala, P. W., Jääskeläinen, A. J., Abdurahman, S., Ogola, J., Masika, M. M., Kivistö, I., Alburkat, H., Plyusnin, I., Levanov, L., Korhonen, E. M., Huhtamo, E., Mwaengo, D., Smura, T., Mirazimi, A., Anzala, O., Vapalahti, O. & Sironen, T., May 2019, In : Emerging Infectious Diseases. 25, 5, p. 955-957 3 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Co-circulation of highly diverse Aleutian mink disease virus strains in Finland

Virtanen, J., Smura, T., Aaltonen, K., Moisander-Jylhä, A-M., Knuuttila, A., Vapalahti, O. & Sironen, T., Feb 2019, In : Journal of General Virology. 100, 2, p. 227-236 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Development, validation and clinical evaluation of a broad-range pan-filovirus RT-qPCR

Jääskeläinen, A. J., Sironen, T., Diagne, C. T., Diagne, M. M., Faye, M., Faye, O., Faye, O., Hewson, R., Mölsä, M., Weidmanng, M. W., Watson, R., Sall, A. A. & Vapalahti, O., May 2019, In : Journal of Clinical Virology. 114, p. 26-31 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Distribution and clinical associations of ljungan virus (Parechovirus B)

Fevola, C., 2019, Helsinki : Helsingin yliopisto. 82 p.

Research output: ThesisDoctoral ThesisCollection of Articles

Identification of a Novel Deltavirus in Boa Constrictors

Hetzel, U., Szirovicza, L., Smura, T., Prahauser, B., Vapalahti, O., Kipar, A. & Hepojoki, J., 2019, In : mBio. 10, 2, 8 p., ARTN e00014-19.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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No Association Between Ljungan Virus Seropositivity and the Beta-cell Damaging Process in the Finnish Type 1 Diabetes Prediction and Prevention Study Cohort

Jääskeläinen, A. J., Nurminen, N., Kolehmainen, P., Smura, T., Tauriainen, S., Toppari, J., Ilonen, J., Veijola, R., Knip, M., Hyöty, H., Vapalahti, O. & Kallio-Kokko, H., Mar 2019, In : Pediatric Infectious Disease Journal. 38, 3, p. 314-316 3 p.

Research output: Contribution to journalArticleScientificpeer-review

Plasma bradykinin concentrations during septic shock determined by a novel LC-MS/MS assay

Lindström, M., Valkonen, M., Tohmola, N., Renkonen, R., Strandin, T., Vaheri, A. & Itkonen, O., Jun 2019, In : Clinica Chimica Acta. 493, p. 20-24 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Predictive mapping of mosquito distribution based on environmental and anthropogenic factors in Taita Hills, Kenya

Uusitalo, R. J., Siljander, M., Culverwell, C. L., Mutai, N., Forbes, K. M., Vapalahti, O. & Pellikka, P. K. E., Apr 2019, In : International Journal of Applied Earth Observation and Geoinformation. 76, p. 84-92 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Recent establishment of tick-borne encephalitis foci with distinct viral lineages in the Helsinki area, Finland

Smura, T., Tonteri, E., Jääskeläinen, A., von Troil, G., Kuivanen, S., Huitu, O., Kareinen, L., Uusitalo, J., Uusitalo, R., Hannila-Handelberg, T., Voutilainen, L., Nikkari, S., Sironen, T., Sane, J., Castrén, J. & Vapalahti, O., 14 May 2019, In : Emerging microbes & infections. 8, 1, p. 675-683 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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Open Access
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2018

A report on the mosquitoes of mainland Åland, southwestern Finland and revised list of Finnish mosquitoes

Culverwell, C. L., Jun 2018, In : Medical & Veterinary Entomology. 32, 2, p. 145-154 10 p.

Research output: Contribution to journalEditorialScientificpeer-review

Characterization of Haartman Institute snake virus-1 (HISV-1) and HISV-like viruses-The representatives of genus Hartmanivirus, family Arenaviridae

Hepojoki, J., Hepojoki, S., Smura, T., Szirovicza, L., Dervas, E., Prahauser, B., Nufer, L., Schraner, E. M., Vapalahti, O., Kipar, A. & Hetzel, U., Nov 2018, In : PLoS Pathogens. 14, 11, 29 p., 1007415.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Differential Regulation of PAI-1 in Hantavirus Cardiopulmonary Syndrome and Hemorrhagic Fever With Renal Syndrome

Bellomo, C., Korva, M., Papa, A., Mäkelä, S., Mustonen, J., Avsic-Zupanc, T., Vaheri, A., Martinez, V. P. & Strandin, T., Feb 2018, In : Open Forum Infectious Diseases. 5, 2, 4 p., 021.

Research output: Contribution to journalArticleScientificpeer-review

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Dobrava hantavirus variants found in Apodemus flavicollis mice in Krklareli Province, Turkey

Polat, C., Sironen, T., Plyusnina, A., Karatas, A., Sozen, M., Matur, F., Vapalahti, O., Oktem, I. M. A. & Plyusnin, A., May 2018, In : Journal of Medical Virology. 90, 5, p. 810-818 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Ecology and evolution of shrew-borne orthohantaviruses in Finland

Ling, J., 2018, Helsinki : [J. Ling]. 102 p.

Research output: ThesisDoctoral ThesisCollection of Articles

Evolution and postglacial colonization of Seewis hantavirus with Sorex araneus in Finland

Ling, J., Smura, T., Tamarit, D., Huitu, O., Voutilainen, L., Henttonen, H., Vaheri, A., Vapalahti, O. & Sironen, T., Jan 2018, In : Infection, genetics and evolution. 57, p. 88-97 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Experimental transmission of Zika virus by Aedes japonicus japonicus from southwestern Germany

Jansen, S., Heitmann, A., Lühken, R., Jöst, H., Helms, M., Vapalahti, O., Schmidt-Chanasit, J. & Tannich, E., 28 Nov 2018, In : Emerging microbes & infections. 7, 6 p., 192.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Open Access
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Galectin-3-binding protein: A multitask glycoprotein with innate immunity functions in viral and bacterial infections

Loimaranta, V., Hepojoki, J., Laaksoaho, O. & Pulliainen, A. T., Oct 2018, In : Journal of Leukocyte Biology. 104, 4, p. 777-786 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Genome Sequences of RIGVIR Oncolytic Virotherapy Virus and Five Other Echovirus 7 Isolates

Hietanen, E., Smura, T., Hakanen, M., Chansaenroj, J., Merilahti, P., Nevalainen, J., Pandey, S., Koskinen, S., Tripathi, L., Poovorawan, Y., Pursiheimo, J-P. & Susi, P., Apr 2018, In : Genome Announcements. 6, 17, 2 p., e00317-18.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Genomic insights about the Lactobacillus genus

Kant, R., 2018, Helsinki: University of Helsinki. 70 p.

Research output: ThesisDoctoral ThesisCollection of Articles

Global Distribution of Human Protoparvoviruses

Vaisanen, E., Mohanraj, U., Kinnunen, P. M., Jokelainen, P., Al-Hello, H., Barakat, A. M., Sadeghi, M., Jalilian, F. A., Majlesi, A., Masika, M., Mwaengo, D., Anzala, O., Delwart, E., Vapalahti, O., Hedman, K. & Soderlund-Venermo, M., Jul 2018, In : Emerging Infectious Diseases. 24, 7, p. 1292-1299 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Hantavirus maintenance and transmission in reservoir host populations

Forbes, K. M., Sironen, T. & Plyusnin, A., Feb 2018, In : Current opinion in virology. 28, p. 1-6 6 p.

Research output: Contribution to journalArticleScientificpeer-review

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High Endemicity and Distinct Phylogenetic Characteristics of Sindbis Virus in Israel

Avizov, N., Zuckerman, N., Orshan, L., Shalom, U., Yeger, T., Vapalahti, O., Israely, T., Paran, N., Melamed, S., Mendelson, E. & Lustig, Y., 1 Nov 2018, In : Journal of Infectious Diseases. 218, 9, p. 1500-1506 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Hjärnskador hos fostret till följd av myggbett - en kort historisk över zikaviruset

Korhonen, E. & Vapalahti, O., 2018, In : Finska Läkaresällskapets Handlingar. 178, 2, p. 73-78 6 p.

Research output: Contribution to journalArticleProfessional

Open Access
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Katsaus dengue- ja zikavirusten diagnostiikkaan ja globaaliin epidemiologiaan

Korhonen, E., 2018, In : Moodi.. 42, 1, p. 12-14 3 p.

Research output: Contribution to journalArticleProfessional

Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood

Stanelle-Bertram, S., Walendy-Gnirss, K., Speiseder, T., Thiele, S., Asante, I. A., Dreier, C., Kouassi, N. M., Preuss, A., Pilnitz-Stolze, G., Mueller, U., Thanisch, S., Richter, M., Scharrenberg, R., Kraus, V., Doerk, R., Schau, L., Herder, V., Gerhauser, I., Pfankuche, V. M., Kaeufer, C. & 28 othersWaltl, I., Moraes, T., Sellau, J., Hoenow, S., Schmidt-Chanasit, J., Jansen, S., Schattling, B., Ittrich, H., Bartsch, U., Renne, T., Bartenschlager, R., Arck, P., Cadar, D., Friese, M. A., Vapalahti, O., Lotter, H., Benites, S., Rolling, L., Gabriel, M., Baumgaertner, W., Morellini, F., Hoelter, S. M., Amarie, O., Fuchs, H., de Angelis, M. H., Loescher, W., de Anda, F. C. & Gabriel, G., Oct 2018, In : Nature Microbiology. 3, 10, p. 1161-+ 17 p.

Research output: Contribution to journalArticleScientificpeer-review

Mikrobilääkeresistenssi One Health - näkökulmasta

Heikinheimo, A., Myllyniemi, A-L. & Vapalahti, O. P., 2018, (In preparation) Mikrobiologia, immunologia ja infektiosairaudet. Duodecim

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Neutrophil Activation in Acute Hemorrhagic Fever With Renal Syndrome Is Mediated by Hantavirus-Infected Microvascular Endothelial Cells

Strandin, T., Mäkelä, S., Mustonen, J. & Vaheri, A., 18 Sep 2018, In : Frontiers in Immunology. 9, 14 p., 2098.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Novel activities of safe-in-human broad-spectrum antiviral agents

Ianevski, A., Zusinaite, E., Kuivanen, S., Strand, M., Lysvand, H., Teppor, M., Kakkola, L., Paavilainen, H., Laajala, M., Kallio-Kokko, H., Valkonen, M., Kantele, A., Telling, K., Lutsar, I., Letjuka, P., Metelitsa, N., Oksenych, V., Bjørås, M., Nordbø, S. A., Dumpis, U. & 14 othersVitkauskiene, A., Öhrmalm, C., Bondeson, K., Bergqvist, A., Aittokallio, T., Cox, R. J., Evander, M., Hukkanen, V., Marjomaki, V., Julkunen, I., Vapalahti, O., Tenson, T., Merits, A. & Kainov, D., Jun 2018, In : Antiviral Research. 154, p. 174-182 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Population-based seroprevalence of Puumala hantavirus in Finland: smoking as a risk factor

Latronico, F., Mäki, S., Rissanen, H., Ollgren, J., Lyytikäinen, O., Vapalahti, O. & Sane, J., Feb 2018, In : Epidemiology and Infection. 146, 3, p. 367-371 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Prostaglandin D2 Receptor DP1 Antibodies Predict Vaccine-induced and Spontaneous Narcolepsy Type 1: Large-scale Study of Antibody Profiling

Sadam, H., Pihlak, A., Kivil, A., Pihelgas, S., Jaago, M., Adler, P., Vilo, J., Vapalahti, O., Neuman, T., Lindholm, D., Partinen, M., Vaheri, A. & Palm, K., Mar 2018, In : EBioMedicine. 29, p. 47-59 13 p.

Research output: Contribution to journalArticleScientificpeer-review

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Reviewing the effects of food provisioning on wildlife immunity

Strandin, T., Babayan, S. A. & Forbes, K. M., 5 May 2018, In : Philosophical Transactions of the Royal Society. Biological Sciences. 373, 1745, 11 p., 20170088.

Research output: Contribution to journalReview ArticleScientificpeer-review

Rift Valley Fever in the Middle East North Africa (MENA) Region

Zakham, F., Alaoui, A. & Vapalahti, O., 1 Dec 2018, In : Current tropical medicine reports. 5, 4, p. 257-263 7 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Semen inhibits Zika virus infection of cells and tissues from the anogenital region

Mueller, J. A., Harms, M., Krueger, F., Gross, R., Joas, S., Hayn, M., Dietz, A. N., Lippold, S., von Einem, J., Schubert, A., Michel, M., Mayer, B., Cortese, M., Jang, K. S., Sandi-Monroy, N., Deniz, M., Ebner, F., Vapalahti, O., Otto, M., Bartenschlager, R. & 4 othersHerbeuval, J-P., Schmidt-Chanasit, J., Roan, N. R. & Muench, J., 7 Jun 2018, In : Nature Communications. 9, 14 p., 2207.

Research output: Contribution to journalArticleScientificpeer-review

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Seroprevalence of lymphocytic choriomeningitis virus and Ljungan virus in Finnish patients with suspected neurological infections

Fevola, C., Kuivanen, S., Smura, T., Vaheri, A., Kallio-Kokko, H., Hauffe, H. C., Vapalahti, O. & Jääskeläinen, A. J., Mar 2018, In : Journal of Medical Virology. 90, 3, p. 429-435 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Sympatric Ixodes-tick species: pattern of distribution and pathogen transmission within wild rodent populations

Cayol, C., Jääskeläinen, A., Koskela, E., Kyröläinen, S., Mappes, T., Siukkola, A. & Kallio, E. R., 9 Nov 2018, In : Scientific Reports. 8, 10 p., 16660.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Taxonomy of the family Arenaviridae and the order Bunyavirales: update 2018

Maes, P., Alkhovsky, S. V., Bao, Y., Beer, M., Birkhead, M., Briese, T., Buchmeier, M. J., Calisher, C. H., Charrel, R. N., Choi, I. R., Clegg, C. S., de la Torre, J. C., Delwart, E., DeRisi, J. L., Di Bello, P. L., Di Serio, F., Digiaro, M., Dolja, V. V., Drosten, C., Druciarek, T. Z. & 79 othersDu, J., Ebihara, H., Elbeaino, T., Gergerich, R. C., Gillis, A. N., Gonzalez, J-P. J., Haenni, A-L., Hepojoki, J., Hetzel, U., Thien Ho, Ni Hong, Jain, R. K., van Vuren, P. J., Jin, Q., Jonson, M. G., Junglen, S., Keller, K. E., Kemp, A., Kipar, A., Kondov, N. O., Koonin, E. V., Kormelink, R., Korzyukov, Y., Krupovic, M., Lambert, A. J., Laney, A. G., LeBreton, M., Lukashevich, I. S., Marklewitz, M., Markotter, W., Martelli, G. P., Martin, R. R., Mielke-Ehret, N., Muehlbach, H-P., Navarro, B., Ng, T. F. F., Teixeira Nunes, M. R., Palacios, G., Paweska, J. T., Peters, C. J., Plyusnin, A., Radoshitzky, S. R., Romanowski, V., Salmenperä, P., Salvato, M. S., Sanfacon, H., Sasaya, T., Schmaljohn, C., Schneider, B. S., Shirako, Y., Siddell, S., Sironen, T. A., Stenglein, M. D., Storm, N., Sudini, H., Tesh, R. B., Tzanetakis, I. E., Uppala, M., Vapalahti, O., Vasilakis, N., Walker, P. J., Wang, G., Wang, L., Wang, Y., Wei, T., Wiley, M. R., Wolf, Y. I., Wolfe, N. D., Wu, Z., Xu, W., Yang, L., Yang, Z., Yeh, S-D., Zhang, Y-Z., Zheng, Y., Zhou, X., Zhu, C., Zirkel, F. & Kuhn, J. H., Aug 2018, In : Archives of Virology. 163, 8, p. 2295-2310 16 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

The molecular tweezer CLR01 inhibits Ebola and Zika virus infection

Roecker, A. E., Mueller, J. A., Dietzel, E., Harms, M., Krueger, F., Heid, C., Sowislok, A., Riber, C. F., Kupke, A., Lippold, S., von Einem, J., Beer, J., Knoell, B., Becker, S., Schmidt-Chanasit, J., Otto, M., Vapalahti, O., Zelikin, A. N., Bitan, G., Schrader, T. & 1 othersMuench, J., Apr 2018, In : Antiviral Research. 152, p. 26-35 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Tuliaisia ulkomaanmatkalta? Zoonoosiviruksia ja niiden diagnostiikkaa

Jääskeläinen, A. J., 2018, In : Moodi.. 42, 1, p. 15-17 3 p.

Research output: Contribution to journalArticleProfessional

2017
Open Access
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Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins

Bulanova, D., Ianevski, A., Bugai, A., Akimov, Y., Kuivanen, S., Paavilainen, H., Kakkola, L., Nandania, J., Turunen, L., Ohman, T., Ala-Hongisto, H., Pesonen, H. M., Kuisma, M. S., Honkimaa, A., Walton, E. L., Oksenych, V., Lorey, M. B., Guschin, D., Shim, J., Kim, J. & 23 othersThan, T. T., Chang, S. Y., Hukkanen, V., Kulesskiy, E., Marjomaki, V. S., Julkunen, I., Nyman, T. A., Matikainen, S., Saarela, J. S., Sane, F., Hober, D., Gabriel, G., De Brabander, J. K., Martikainen, M., Windisch, M. P., Min, J-Y., Bruzzone, R., Aittokallio, T., Vaha-Koskela, M., Vapalahti, O., Pulk, A., Velagapudi, V. & Kainov, D. E., Oct 2017, In : Viruses. 9, 10, 15 p., 271.

Research output: Contribution to journalArticleScientificpeer-review

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Co-infecting Reptarenaviruses Can Be Vertically Transmitted in Boa Constrictor

Keller, S., Hetzel, U., Sironen, T., Korzyukov, Y., Vapalahti, O., Kipar, A. & Hepojoki, J., Jan 2017, In : PLoS Pathogens. 13, 1, 21 p., 1006179.

Research output: Contribution to journalArticleScientificpeer-review

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Compensating for cross-reactions using avidity and computation in a suspension multiplex immunoassay for serotyping of Zika versus other flavivirus infections

Ronnberg, B., Gustafsson, A., Vapalahti, O., Emmerich, P., Lundkvist, A., Schmidt-Chanasit, J. & Blomberg, J., Oct 2017, In : Medical Microbiology and Immunology. 206, 5, p. 383-401 19 p.

Research output: Contribution to journalArticleScientificpeer-review

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Development of a high-throughput colorimetric Zika virus infection assay

Mueller, J. A., Harms, M., Schubert, A., Mayer, B., Jansen, S., Herbeuval, J-P., Michel, D., Mertens, T., Vapalahti, O., Schmidt-Chanasit, J. & Muench, J., Apr 2017, In : Medical Microbiology and Immunology. 206, 2, p. 175-185 11 p.

Research output: Contribution to journalArticleScientificpeer-review

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Differences in the growth properties of Zika virus foetal brain isolate and related epidemic strains in vitro

Kuivanen, S., Korhonen, E. M., Helisten, A-A., Huhtamo, E., Smura, T. & Vapalahti, O., Jul 2017, In : Journal of General Virology. 98, 7, p. 1744-1748 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

DISTRIBUTION AND SEASONAL VARIATION OF LJUNGAN VIRUS IN BANK VOLES (MYODES GLAREOLUS) IN FENNOSCANDIA

Fevola, C., Rossi, C., Rosa, R., Nordstrom, A., Ecke, F., Magnusson, M., Miller, A. L., Niemimaa, J., Olsson, G. E., Jaaskelainen, A. J., Hornfeldt, B., Henttonen, H. & Hauffe, H. C., Jul 2017, In : Journal of Wildlife Diseases. 53, 3, p. 552-560 9 p.

Research output: Contribution to journalArticleScientificpeer-review