Research output per year
Research output per year
Organisation profile
Organisation Profile
Our research group has for decades studied the pathogenicity, clinical picture, and immunological responses against DNA viruses. We have specialized in the study of the human eukaryotic virome, with the aim of understanding the role of persistent viruses in the human body.
Our approach is multifaceted, as we investigate the impact of the human virome from the virus, the immune system, and the host perspectives.
We have strong know-how in method development,antibody (EIA, FRET) and nucleic acid-based (qPCR, NGS)
Fields of Science
- 3111 Biomedicine
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Leo Hannolainen
- Virus infections and immunity - Doctoral Researcher
- Department of Virology - Doctoral Researcher
- Doctoral Programme in Biomedicine
Person: U1 Research and teaching staff, Doctoral Researcher
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Klaus Hedman
- Medicum - Prof. emer.
- Department of Virology
- Doctoral Programme in Integrative Life Science - Supervisor for doctoral programme
- Doctoral Programme in Biomedicine - Supervisor for doctoral programme
- Virus infections and immunity
- HUS Chemistry and Microbiology
Person: UH , U4 Research and teaching staff
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Visa Nurmi
- Medicum - Grant-funded researcher
- Doctoral Programme in Biomedicine
- Virus infections and immunity
Person: Visiting scholar, U1 Research and teaching staff, Doctoral Researcher
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Maria Perdomo
- Faculty Common Matters (Faculty of Medicine) - Title of Docent
- Department of Virology - Clinical Instructor
- Doctoral Programme in Biomedicine - Supervisor for doctoral programme
- Doctoral Programme in Oral Sciences - Supervisor for doctoral programme
- Virus infections and immunity
Person: U3 Research and teaching staff
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B cell dysregulation during acute COVID-19 is transient
Jokiranta, S. T., Ngoc, A. N., Huang, X., Nowlan, K., Hannolainen, L., Pyöriä, L., Pekkarinen, P. T., Dürnsteiner, P., Lääveri, T., Heikkilä, N., Heinonen, S., Laakso, S. M., Kantele, A., Vapalahti, O., Strandin, T., Hepojoki, J., Perdomo, M. F. & Kekäläinen, E., Feb 2026, In: Immunology Letters. 277, 11 p., 107086.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
A customizable multiplex protein microarray for antibody testing and its application for tick-borne and other infectious diseases
Krishnamurthy, H. K., Jayaraman, V., Krishna, K., Wang, T., Bei, K., Changalath, C., Matilda, S., Rai, A. J., Welc-Falęciak, R., Pawełczyk, A., Blanton, L. S., Chrdle, A., Fořtová, A., Růžek, D., Nasrallah, G. K., Abu-Raddadi, L. J., Al-Sadeq, D. W., Abdallah, M. A. A., Lilleri, D. & Fornara, C. & 10 others, , 20 Jan 2025, In: Scientific Reports. 15, 1, 12 p., 2527.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Altered immune landscape of cervical lymph nodes reveals Epstein-Barr virus signature in multiple sclerosis
Sarkkinen, J., Yohannes, D. A., Kreivi, N., Dürnsteiner, P., Elsakova, A., Huuhtanen, J., Nowlan, K., Kurdo, G., Linden, R., Saarela, M., Tienari, P. J., Kekäläinen, E., Perdomo, M. & Laakso, S. M., 21 Feb 2025, In: Science immunology. 10, 104, 15 p., eadl3604.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
An evaluation of computational methods for reconstruction of human viral DNA genomes
Sousa, M. J. P., Toppinen, M., Pyöriä, L., Hedman, K., Sajantila, A., Perdomo, M. F. & Pratas, D. R. M., 26 Dec 2025, In: GigaScience. 23 p., giaf159.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Human Parvoviruses, Including Parvovirus B19, Human Bocaviruses, and Adeno-Associated Viruses (AAVs)
Hedman, K., Toppinen, M. & Söderlund-Venermo, M., 2025, Mandell, Douglas, and Bennett's principles and practice of infectious diseases. Blaser, M. J., Cohen, J. I. & Holland, S. M. (eds.). 10th ed. ed. ElsevierResearch output: Chapter in Book/Report/Conference proceeding › Chapter › Professional
Activities
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The next generation of clinical virology
Perdomo , M. (Speaker)
2 Sept 2023Activity: Talk or presentation types › Oral presentation
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Reviewer of doctoral thesis
Hedman, K. (Pre-examiner)
2023Activity: Examination types › Supervisor or co-supervisor of doctoral thesis
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Virology Days
Hannolainen, L. (Attendee)
30 Mar 2023 → 31 Mar 2023Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Unmasking the eukaryotic DNA virome in humans
Perdomo , M. (Speaker)
26 Jun 2023 → 28 Jun 2023Activity: Talk or presentation types › Oral presentation
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Reactivation of chromosomally integrated HHV-6 in a solid transplant recipient
Perdomo , M. (Speaker)
23 Jan 2023 → 24 Jan 2023Activity: Talk or presentation types › Oral presentation
Prizes
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Best PhD thesis in Faculty of Medicine, University of Helsinki in 2021
Toppinen, M. (Recipient), 3 Mar 2022
Prize: Prizes and awards
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Press/Media
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Suomalainen tutkija löysi kuolleen miehen aivoista viruksen, mikä saattaa mullistaa käsityksemme ihmiskehosta
08/04/2023
1 item of Media coverage
Press/Media: Press / Media
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Smallpox, A Not So Ancient Disease, May Have Emerged In More Recent Times
09/12/2016
1 item of Media coverage
Press/Media: Press / Media