Research Output per year
Research Output per year
Personal profile
Description of research and teaching
Development of new radiotracers for brain research and for studying nanoparticle mediated drug delivery with positron emission tomography (PET) and single photon emission tomography (SPECT).
Teaching at courses: Radiopharmaceutical chemistry, Radionuclide production and tracer techniques, and Organic chemistry I.
Curriculum vitae
Current position:
Group leader in Radiopharmaceutical chemistry (since 2008)
Education:
Doctor of Philosophy (Ph.D.), University of Kuopio, Finland, Major subject: Biochemistry, Research field: Chemistry in Biosciences (2003). Topic of the doctoral dissertation: New tropane analogues as potential brain imaging agents: Synthesis, conformational study and in vitro/in vivo evaluation.
Docent in Radiochemistry, University of Helsinki, Finland (2011).
Post-doctoral research positions:
Vrije Universiteit, Radionuclidencentrum/Vrije Universiteit Medisch Centrum, Nucleaire Geneeskunde en PET Research, Amsterdam, The Netherlands (2002 - 2004).
Karolinska Institutet, Department of Clinical neuroscience, Section of Psychiatry, Stockholm, Sweden (2005- 2006).
University of Helsinki, Department of Chemistry, Laboratory of Radiochemistry (Academy of Finland, Postdoctoral researcher´s project: 2007 - 2009, Academy research fellow 2010 - 2016).
Fields of Science
- 116 Chemical sciences
- radiopharmaceutical chemistry
- positron emission tomography
- single photon emission computed tomography
- PET
- SPECT
- nanotechnology
International and National Collaboration
Publications and projects within past five years.
Publications
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Addressing the Biochemical Foundations of a Glucose-Based "Trojan Horse"-Strategy to Boron Neutron Capture Therapy: From Chemical Synthesis to In Vitro Assessment
Matovic, J., Järvinen, J., Bland, H. C., Sokka, I. K., Imlimthan, S., Ferrando, R. M., Huttunen, K. M., Timonen, J., Peräniemi, S., Aitio, O., Airaksinen, A. J., Sarparanta, M., Johansson, M. P., Rautio, J. & Ekholm, F. S., 5 Oct 2020, In : Molecular Pharmaceutics. 17, 10, p. 3885-3899 15 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Comparison of clinically relevant oncolytic virus platforms for enhancing T-cell therapy of solid tumors
Cervera-Carrascon, V., Quixabeira, D. C. A., Havunen, R., Santos, J. M., Kutvonen, E., Clubb, J. H. A., Siurala, M., Heiniö, C., Zafar, S., Koivula, T., Lumen, D., Vaha, M., Garcia-Horsman, A., Airaksinen, A. J., Sorsa, S., Anttila, M., Hukkanen, V., Kanerva, A. & Hemminki, A., 26 Jun 2020, In : Molecular Therapy - Oncolytics. 17, p. 47-60 14 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Engineered antibody-functionalized porous silicon nanoparticles for therapeutic targeting of pro-survival pathway in endogenous neuroblasts after stroke
Balasubramanian, V., Domanskyi, A., Renko, J-M., Sarparanta, M., Wang, C-F., Rebelo Correia, A. M., Mäkilä, E., Alanen, O., Salonen, J., Airaksinen, A., Tuominen, R. K., Hirvonen, J., Airavaara, M. & Santos, H. A., Jan 2020, In : Biomaterials. 227, 11 p., 119556.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Evaluation of Organo [F-18]Fluorosilicon Tetrazine as a Prosthetic Group for the Synthesis of PET Radiotracers
Otaru, S., Imlimthan, S., Sarparanta, M., Helariutta, K., Wähälä, K. & Airaksinen, A., 1 Mar 2020, In : Molecules. 25, 5, 17 p., 1208.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Metabolism of a Bioorthogonal PET Tracer Candidate [F-19/F-18]SiFA-Tetrazine in Mouse Liver Microsomes: Biotransformation Pathways and Defluorination Investigated by UHPLC-HRMS
Otaru, S., Niemikoski, H., Sarparanta, M. & Airaksinen, A. J., 3 Aug 2020, In : Molecular Pharmaceutics. 17, 8, p. 3106-3115 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
Projects
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PET and SPECT in drug delivery research
Ranjan, S. & Airaksinen, A.
01/03/2014 → …
Project: Research project
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New Radiopharmaceuticals for molecular imaging and targeted drug delivery into injured myocardium
Ranjan, S. & Airaksinen, A.
01/03/2014 → …
Project: Research project
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Medical Physics in Clinical and Preclinical research
Savolainen, S., Kortesniemi, M., Sipilä, O., Kuronen, A., Airaksinen, A., Bergström, K., Heikkinen, S., Kosunen, A., Timonen, M., Salli, E., Uusi-Simola, J., Reijonen, V., Hippeläinen, E. T., Kuusela, L., Vitikainen, A., Ihalainen, T., Kaasalainen, T. T., Pitkonen, M., Turunen, S., Mäkelä, T. O. & Sairanen, V.
01/01/2013 → …
Project: Research project
File -
New radiotracers for imaging in drug delivery
Airaksinen, A., Helariutta, K., Sarparanta, M. & Kallinen, A.
01/01/2008 → …
Project: Research project
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New radiopharmaceuticals for brain imaging
Airaksinen, A., Bergström, K., Helariutta, K., Kämäräinen, E. & Koivula, T.
01/01/2000 → …
Project: Research project
Prizes
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The best publication in nuclear medicine in 2014 in Finland
Airaksinen, Anu (Recipient), 2014
Prize: Prizes and awards
Activities
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Supervision of PhD-studies
Anu Airaksinen (Supervisor)
2016 → …Activity: Examination types › Supervisor or co-supervisor of doctoral thesis
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9th International Conference on Nuclear and Radiochemistry NRC9
Anu Airaksinen (Attendee)
29 Aug 2016 → 2 Sep 2016Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Finnish Chemical Society (External organisation)
Anu Airaksinen (Board member)
2015 → …Activity: Membership types › Membership or other role in national/international committee, council, board
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Journal of Labelled Compounds & Radiopharmaceuticals (Journal)
Anu Airaksinen (Reviewer)
2015 → …Activity: Publication peer-review and editorial work types › Peer review of manuscripts
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Pre-examiner of a doctoral thesis
Anu Airaksinen (Pre-examiner)
2015Activity: Examination types › Pre-examiner of doctoral thesis