Research output per year
Research output per year
Personal profile
Education information
PhD Food Sciences (Food Chemistry)
University of Helsinki (2016)
Description of research and teaching
Natural Fortification of Vitamin B12 in Plant-based Foods by Microbial in situ Synthesis
Potential of microbes to synthesize in situ vitamins can be exploited to naturally fortify foods and to synthesize vitamins to new matrices. In our research group, we study vitamin B12 synthesis focusing on bacteria which are allowed to be used in food production. The focus is on Propionibacterium freudenreichii, especially its vitamin B12 synthesis mechanisms and factors affecting efficiency of the synthesis. Integrating tools of molecular microbiology with those of food chemistry and technology will give excellent ground for scientific breakthroughs. On the other hand, understanding the molecular mechanisms governing in situ vitamin B12 production will enable new innovations in production of science-based functional foods and ingredients.
Education/Academic qualification
PhD Food Sciences
Fields of Science
- 416 Food Science
- Food chemistry
- Vitamins
- Vitamin B12
- cereals
- Fermentation
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Fermentation of faba bean flour as a pre-treatment in high-moisture extrusion for simultaneous fortification of vitamin B12 and reduction of raffinose oligosaccharides in meat analogues
Kantanen, K. A., Chamlagain, B., Succi, V., Seppänen, S. T. M., Edelmann, M., Siitonen, A., Kemppinen, L. K., Kemppinen, A., Kangas, M. H., Varmanen, P., Piironen, V. & Jouppila, K., 5 Dec 2024, In: Future Foods. 10, 100518.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Vitamin B12 production in solubilized protein extract of bioprocessed wheat bran with Propionibacterium freudenreichii
Chamlagain, B., Edelmann, M., Katina, K., Varmanen, P. & Piironen, V., 15 Jan 2024, In: LWT-Food Science and Technology. 192, 7 p., 115731.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Bioaccessibility of vitamin B12 synthesized by Propionibacterium freudenreichii and from products made with fermented wheat bran extract
Chamlagain, B., Peltonen, L., Edelmann, M., Ramos-Diaz, J. M., Kemppinen, A., Jouppila, K., Varmanen, P. & Piironen, V., 2021, In: Current research in food science. 4, p. 499-502 4 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Ultra-high performance liquid chromatographic and mass spectrometric analysis of active vitamin B12 in cells of Propionibacterium and fermented cereal matrices
Chamlagain, B., Edelmann, M., Kariluoto, S., Ollilainen, V. & Piironen, V., 2015, In: Food Chemistry. 166, p. 630-638 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Effect of the lower ligand precursors on vitamin B12 production by food-grade Propionibacteria
Chamlagain, B., Deptula, P., Edelmann, M., Kariluoto, S., Grattepanche, F., Lacroix, C., Varmanen, P. & Piironen, V., 2016, In: LWT-Food Science and Technology. 72, p. 117-124 8 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
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B12WEGAIN: Natural vitamin B12 fortification of future foods by bioprocessing and controlled cell-lysis of Propionibacterium freudenreichii
Varmanen, P. (Project manager), Piironen, V. (Principal Investigator), Sillanpää, L. A. (Participant), Loivamaa, I. (Participant), Savijoki, K. (Participant), Chamlagain, B. (Participant) & Edelmann, M. (Participant)
01/01/2021 → 31/12/2023
Project: Research project
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Molecular basis for natural vitamin B12 fortification of emerging new foods by utilization of Propionibacterium freudenreichii
Piironen, V. (Principal Investigator), Loivamaa, I. (Participant), Edelmann, M. (Participant), Chamlagain, B. (Participant), Savijoki, K. (Participant), Varmanen, P. (Project manager), Sillanpää, L. A. (Participant) & Zhang, R. (Participant)
01/09/2019 → 31/08/2023
Project: Research project
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Leg4Life: Legumes for sustainable food system and healthy life
Pajari, A.-M. (Principal Investigator), Piironen, V. (Co-Principal Investigator), Vanhatalo, A. (Participant), Simojoki, A. (Participant), Jouppila, K. (Participant), Kariluoto, S. (Participant), Päivärinta, E. (Participant), Konttinen, H. (Participant), Hyytiäinen, K. (Participant), Lombardini (former Lombardini-Riipinen), C. (Participant), Lamminen, M. (Participant), Alakukku, L. (Participant), Chamlagain, B. (Participant), Coda, R. (Participant), Ertbjerg, P. (Participant), Edelmann, M. (Participant), Halmemies-Beauchet-Filleau, A. (Participant), Itkonen, S. (Participant), Katina, K. (Participant), Knaapila, A. (Participant), Kokkonen, T. (Participant), Kuoppala, K. (Participant), Lampi, A.-M. (Participant), Mäkelä, P. (Participant), Nurmi, V. (Participant), Ramos-Diaz, J. M. (Participant), Salonen, A. (Participant), Sandell, M. (Participant), Sihvonen, M. (Participant), Sontag-Strohm, T. (Participant), Stoddard, F. (Participant), Tenkanen, M. (Participant) & Varmanen, P. (Project manager)
01/06/2019 → 31/08/2025
Project: Research project
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BIOB12: Vitamin B12-bioenriched wheat bran ingredients for food applications (BIOB12)
Piironen, V. (Project manager), Chamlagain, B. (Participant), Edelmann, M. (Participant), Varmanen, P. (Participant) & Katina, K. (Participant)
01/07/2018 → 30/06/2019
Project: Research project
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BIOFORCE: Bio-enriched bran ingredients - in situ synthesis of vitamin B12 and folate with propionibacteria and lactic acid bacteria
Piironen, V. (Project manager), Varmanen, P. (Principal Investigator), Chamlagain, B. (Participant), Edelmann, M. (Participant) & Katina, K. (Principal Investigator)
01/03/2017 → 31/03/2018
Project: Research project
Prizes
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"Best Doctoral Thesis Award" by Doctoral Programme in Food Chain and Health
Chamlagain, B. (Recipient), 15 Nov 2017
Prize: Prizes and awards
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"Best Doctoral Dissertation Award" by The Finnish Society of Food Science and Technology (ETS)
Chamlagain, B. (Recipient), 21 Mar 2017
Prize: Prizes and awards
Activities
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Co-examiner of Palni Kundra's Doctoral dissertation at ETH Zurich
Chamlagain, B. (Opponent)
21 Jun 2023Activity: Examination types › Opponent of doctoral dissertation
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Supervision of Master thesis (Siri Seppänen)
Chamlagain, B. (Supervisor)
Mar 2021 → Sept 2021Activity: Examination types › Supervision of other thesis (Master's, Licentiate)
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Supervision of Master thesis (Valentina Succi)
Chamlagain, B. (Supervisor)
24 Feb 2020 → 24 Aug 2020Activity: Examination types › Supervision of other thesis (Master's, Licentiate)
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Institute of Food, Nutrition and Health (IFNH) seminars, ETH Zurich
Chamlagain, B. (Speaker)
29 Oct 2019Activity: Talk or presentation types › Invited talk
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Supervision of Master thesis (Liisa Peltonen)
Chamlagain, B. (Supervisor)
Nov 2018 → …Activity: Examination types › Supervision of other thesis (Master's, Licentiate)
Press/Media
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Fermentoinnilla kasviperäisiin elintarvikkeisiin B12-vitamiinia luonnollisesti
Piironen, V., Varmanen, P. K., Chamlagain, B. S., Edelmann, J. M. & Deptula, P.
02/01/2017
1 Media contribution
Press/Media: Press / Media