Photo of Dongfei Liu
  • PL 56 (Viikinkaari 5)

    00014

    Finland

Accepting PhD Students

20092020
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Publications 2009 2019

2019

Acetalated Dextran Nanoparticles Loaded into an Injectable Alginate Cryogel for Combined Chemotherapy and Cancer Vaccination

Bauleth-Ramos, T., Ting-Yu Shih, T-Y. S., Shahbazi, M-A., Najibi, A. J., Mao, A. S., Liu, D., Granja, P., Santos, H. A., Sarmento, B. & Mooney, D. J., 27 Jun 2019, (Accepted/In press) In : Advanced Functional Materials. p. 1903686 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Close-loop dynamic nanohybrids on collagen-ark with in situ gelling transformation capability for biomimetic stage-specific diabetic wound healing

Liu, Z., Li, Y., Li, W., Lian, W., Kemell, M., Hietala, S., Figueiredo, P., Li, L., Mäkilä, E., Ma, M., Salonen, J., Hirvonen, J. T., Liu, D., Zhang, H., Deng, X. & Santos, H. A., 1 Feb 2019, In : Materials Horizons. 6, 2, p. 385-393 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Electrospun Fibrous Architectures for Drug Delivery, Tissue Engineering and Cancer Therapy

Ding, Y., Li, W., Zhang, F., Liu, Z., Ezazi, N. Z., Liu, D. & Santos, H. A., Jan 2019, In : Advanced Functional Materials. 29, 2, 35 p., 1802852.

Research output: Contribution to journalReview ArticleScientificpeer-review

Microfluidic mixing and devices for preparing nanoparticulate drug delivery systems

Zhang, Y., Liu, D., Zhang, H. & Almeida Santos, H., 2019, Microfluidics for Pharmaceutical Applications: From Nano/Micro Systems Fabrication to Controlled Drug Delivery. Santos, H. A., Liu, D. & Zhang, H. (eds.). 1st ed. San Diego: Elsevier, p. 155-177 23 p. (Micro and Nano Technologies).

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Microfluidics for Pharmaceutical Applications: From Nano/Micro Systems Fabrication to Controlled Drug Delivery

Almeida Santos, H. (ed.), Liu, D. (ed.) & Zhang, H. (ed.), 2019, 1st ed. Amsterdam: Elsevier Scientific Publ. Co. 495 p. ( Micro & nano technologies)

Research output: Book/ReportBookScientificpeer-review

2018

Biodegradable Spheres Protect Traumatically Injured Spinal Cord by Alleviating the Glutamate-Induced Excitotoxicity

Liu, D., Chen, J., Jiang, T., Li, W., Huang, Y., Lu, X., Liu, Z., Zhang, W., Zhou, Z., Ding, Q., Almeida Santos, H., Yin, G. & Fan, J., 14 Feb 2018, In : Advanced Materials. 30, 14, 11 p., 1706032.

Research output: Contribution to journalArticleScientificpeer-review

Current developments and applications of microfluidic technology toward clinical translation of nanomedicines

Liu, D., Zhang, H., Fontana, F., Hirvonen, J. T. & Almeida Santos, H., 15 Mar 2018, In : Advanced Drug Delivery Reviews. 128, p. 54-83 30 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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Development of Biohybrid Multistage Nanovaccines for Melanoma

Fontana, F., Capasso, C., Shahbazi, M-A., Liu, D., Fusciello, M., Feola, S., Zhang, H., Mäkilä, E., Salonen, J., Hirvonen, J. T., Cerullo, V. & Almeida Santos, H., 2018, (Accepted/In press).

Research output: Conference materialsAbstractResearchpeer-review

Dual‐drug delivery using dextran‐functionalized nanoparticles targeting cardiac fibroblasts for cellular reprogramming

Ferreira, M. P. A., Talman, V., Torrieri, G., Liu, D., Marques, G., Moslova, K., Liu, Z., Pinto, J. F., Hirvonen, J., Ruskoaho, H. & Santos, H. A., 11 Apr 2018, In : Advanced Functional Materials. 28, 15, 12 p., 1705134.

Research output: Contribution to journalArticleScientificpeer-review

Electrospun Polyhydroxybutyrate/Poly(epsilon-caprolactone)/Sol-Gel-Derived Silica Hybrid Scaffolds with Drug Releasing Function for Bone Tissue Engineering Applications

Ding, Y., Li, W., Correia, A., Yang, Y., Zheng, K., Liu, D., Schubert, D. W., Boccaccini, A. R., Santos, H. A. & Roether, J. A., 2 May 2018, In : ACS Applied Materials & Interfaces. 10, 17, p. 14540-14548 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Engineered Multifunctional Albumin-Decorated Porous Silicon Nanoparticles for FcRn Translocation of Insulin

Martins, J. P., D’Auria, R., Liu, D., Fontana, F., Ferreira, M. P. A., Correia, A., Kemell, M., Moslova, K., Mäkilä, E., Salonen, J., Casettari, L., Hirvonen, J., Sarmento, B. & Santos, H. A., 5 Jul 2018, In : Small. 14, 27, 11 p., 1800462.

Research output: Contribution to journalArticleScientificpeer-review

Hierarchical structured and programmed vehicles deliver drugs locally to inflamed sites of intestine

Li, W., Li, Y., Liu, Z., Kerdsakundee, N., Zhang, M., Zhang, F., Liu, X., Bauleth-Ramos, T., Mäkilä, E., Kemell, M., Ding, Y., Sarmento, B., Wiwattanapatapee, R., Salonen, J., Zhang, H., Hirvonen, J. T., Liu, D., Deng, X. & Santos, H. A., Dec 2018, In : Biomaterials. 185, p. 322-332 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Impact of Pore Size and Surface Chemistry of Porous Silicon Particles and Structure of Phospholipids on Their Interactions

Liu, D., Lipponen, K., Quan, P., Wan, X., Zhan, H., Makilä, E., Salonen, J., Kostiainen, R., Hirvonen, J., Kotiaho, T. & Santos, H. A., Jul 2018, In : Acs Biomaterials Science & Engineering. 4, 7, p. 2308-2313 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Inside Front Cover - Neuroprotection: Biodegradable Spheres Protect Traumatically Injured Spinal Cord by Alleviating the Glutamate‐Induced Excitotoxicity (Adv. Mater. 14/2018)

Liu, D., Chen, J., Jiang, T., Li, W., Liu, Z., Huang, Y., Lu, X., Zhang, W., Zhou, Z., Ding, Q., Almeida Santos, H., Yin, G. & Fan, J., 14 Feb 2018

Research output: Non-textual formDesignArt in non-art workpeer-review

Manipulating Superparamagnetic Microparticles with an Electromagnetic Needle

Cenev, Z., Zhang, H., Sariola, V., Rahikkala, A. T. A., Almeida Santos, H., Liu, D. & Zhou, Q., 15 Jan 2018, In : Advanced Materials Technologies. 3, 1, 9 p., 1700177.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Multifunctional Nanohybrid Based on Porous Silicon Nanoparticles, Gold Nanoparticles and Acetalated Dextran for Liver Regeneration and Acute Liver Failure Theranostics

Liu, Z., Li, Y., Li, W., Xiao, C., Liu, D., Dong, C., Zhang, M., Mäkilä, E., Kemell, M., Salonen, J., Hirvonen, J. T., Zhang, H., Zhou, D., Deng, X. & Santos, H. A., 13 Jun 2018, In : Advanced Materials. 30, 24, 10 p., 1703393 .

Research output: Contribution to journalArticleScientificpeer-review

pH And Reactive Oxygen Species-Sequential Responsive Nano-in-Micro Composite For Targeted Therapy of Inflammatory Bowel Disease

Bertoni, S., Liu, Z., Rebelo Correia, A. M., Oliveira Martins, J. P., Rahikkala, A. T. A., Fontana, F., Kemell, M. L., Liu, D., Albertini, B., Passerini, N., Li, W. & Almeida Santos, H., 12 Dec 2018, In : Advanced Functional Materials. 28, 50, p. 1806175 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Production of Pure Drug Nanocrystals and Nano Co-crystals by Confinement Methods

Fontana, F., Figueiredo, P. I., Zhang, P., Hirvonen, J. T., Liu, D. & Almeida Santos, H., Jun 2018, In : Advanced Drug Delivery Reviews. 131, p. 3-21 19 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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Sequential Antifouling Surface for Efficient Modulation of the Nanoparticle-Cell Interactions in Protein-Rich Environment

Zhang, F., Kong, L., Liu, D., Li, W., Mäkilä, E., Correia, A., Lindgren, R., Salonen, J., Hirvonen, J. T., Zhang, H., Kros, A. & Almeida Santos, H., May 2018, In : Advanced Therapeutics. 1, 1, p. 1800013 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Tailoring porous silicon for biomedical applications: from drug delivery to cancer immunotherapy

Li, W., Liu, Z., Fontana, F., Ding, Y., Liu, D., Hirvonen, J. T. & Almeida Santos, H., 13 Jun 2018, In : Advanced Materials. 30, 24, 38 p., 1703740.

Research output: Contribution to journalReview ArticleScientificpeer-review

2017

A Nano-in-Nano Vector: Merging the Best of Polymeric Nanoparticles and Drug Nanocrystals

Liu, D., Rodríguez Bernuz, C., Fan, J., Li, W., Correia, A., Hirvonen, J. T. & Almeida Santos, H., 3 Mar 2017, In : Advanced Functional Materials. 27, 9, 13 p., 1604508.

Research output: Contribution to journalArticleScientificpeer-review

Back Cover Drug Delivery: A Nano-in-Nano Vector: Merging the Best of Polymeric Nanoparticles and Drug Nanocrystals

Liu, D., Rodríguez Bernuz, C., Fan, J., Li, W., Rebelo Correia, A. M., Hirvonen, J. T. & Almeida Santos, H., 3 Mar 2017

Research output: Non-textual formDigital or Visual ProductsSolo art productionpeer-review

Open Access

Core/Shell Nanocomposites Produced by Superfast Sequential Microfluidic Nanoprecipitation

Liu, D., Zhang, H., Cito, S., Fan, J., Mäkilä, E., Salonen, J., Hirvonen, J., Sikanen, T. M., Weitz, D. A. & Santos, H. A., Feb 2017, In : Nano Letters. 17, 2, p. 606-614 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Delivery of therapeutics with nanoparticles: what's new in cancer immunotherapy?

Fontana, F., Liu, D., Hirvonen, J. & Santos, H. A., 2017, In : Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 9, 1, 26 p., 1421.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access

Development of Multistaged Nanoparticles as Cancer Vaccines

Fontana, F., Shahbazi, M-A., Liu, D., Zhang, H., Mäkilä, E., Salonen, J., Hirvonen, J. T. & Almeida Santos, H., 2017.

Research output: Conference materialsAbstractResearchpeer-review

Front Cover Picture - Cancer Therapy:Nutlin-3a and Cytokine co-loaded Spermine-modified Acetalated Dextran Nanoparticles for Cancer Chemo-immunotherapy

Bauleth-Ramos, T., Shahbazi, M-A., Liu, D., Fontana, F., Correia, A., Figueiredo, P. I., Zhang, H., Oliveira Martins, J. P., Hirvonen, J. T., Granja, P., Sarmento, B. & Almeida Santos, H., 10 Nov 2017

Research output: Non-textual formDigital or Visual ProductsSolo art productionpeer-review

Inside Cover Image: Delivery of Therapeutics With Nanoparticles: What’s New in Cancer Immunotherapy?

Fontana, F., Liu, D., Hirvonen, J. T. & Almeida Santos, H., Jan 2017

Research output: Non-textual formDigital or Visual ProductsSolo art productionpeer-review

Open Access

Microfluidic assembly of a nano-in-micro dual drug delivery platform composed of halloysite nanotubes and a pH-responsive polymer for colon cancer therapy

Li, W., Liu, D., Zhang, H., Correia, A., Mäkilä, E., Salonen, J., Hirvonen, J. & Santos, H. A., 15 Jan 2017, In : Acta Biomaterialia. 48, p. 238-246 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Microfluidic-Assisted Fabrication of Carriers for Controlled Drug Delivery

Liu, D., Zhang, H., Fontana, F., Hirvonen, J. T. & Almeida Santos, H., 7 Jun 2017, In : Lab on a Chip. 17, 11, p. 1856-1883 28 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Microfluidic Encapsulation of Prickly Zinc-Doped Copper Oxide Nanoparticles with VD1142 Modified Spermine Acetalated Dextran for Efficient Cancer Therapy

Zhang, H., Liu, D., Wang, L., Liu, Z., Wu, R., Janoniene, A., Ma, M., Pan, G., Baranauskiene, L., Zhang, L., Cui, W., Petrikaite, V., Matulis, D., Zhao, H., Pan, J. & Santos, H. A., 7 Jun 2017, In : Advanced Healthcare Materials. 6, 11, 13 p., 1601406.

Research output: Contribution to journalArticleScientificpeer-review

Multistaged Nanovaccines based on Porous Silicon@Acetalated Dextran@Cancer Cell Membrane for Cancer Immunotherapy

Fontana, F., Shahbazi, M-A., Liu, D., Zhang, H., Mäkilä, E., Salonen, J., Hirvonen, J. T. & Almeida Santos, H., 13 Feb 2017, In : Advanced Materials. 29, 7, 9 p., 1603239.

Research output: Contribution to journalArticleScientificpeer-review

NANOPARTICLE WITH SUPER HIGH-DRUG LOADING CAPACITY AND MANUFACTURING METHOD THEREOF

Liu, D., Fan, J., Yin, G. & Almeida Santos, H., 23 Nov 2017, IPC No. A61K 9/51 (2006.01), A61K 47/38 (2006.01), A61K 47/12 (2006.01), A61K 47/26 (2006.01), A61K 47/32 (2006.01), A61K 31/337 (2006.01), A61K 31/44 (2006.01), A61K 31/635 (2006.01), A61K 31/4745 (2006.01), A61K 31/355 (2006.01), A61K 38/28 (2006.01), A61K 31/573 (2006.01), Patent No. WO2017198078

Research output: PatentScientific

Nutlin-3a and Cytokine Co-loaded Spermine-Modified Acetalated Dextran Nanoparticles for Cancer Chemo-Immunotherapy

Bauleth-Ramos, T., Shahbazi, M-A., Liu, D., Fontana, F., Correia, A., Figueiredo, P., Zhang, H., Martins, J. P., Hirvonen, J. T., Granja, P., Sarmento, B. & Santos, H. A., 10 Nov 2017, In : Advanced Functional Materials. 27, 42, 14 p., 1703303.

Research output: Contribution to journalArticleScientificpeer-review

Photoluminescent Hybrids of Cellulose Nanocrystals and Carbon Quantum Dots as Cytocompatible Probes for in vitro Bio-imaging

Guo, J., Liu, D., Filpponen, I., Johansson, L-S., Malho, J-M., Quraishi, S., Liebner, F., Almeida Santos, H. & J. Rojas, O., Jul 2017, In : Biomacromolecules. 18, 7, p. 2045–2055 11 p.

Research output: Contribution to journalArticleScientificpeer-review

The Impact of Porous Silicon Nanoparticles on Human Cytochrome P450 Metabolism in Human Liver Microsomes In Vitro

Ollikainen, E., Liu, D., Kallio, A., Mäkilä, E., Zhang, H., Salonen, J., Almeida Santos, H. & Sikanen, T. M., 15 Jun 2017, In : European Journal of Pharmaceutical Sciences. 104, p. 124–132 9 p.

Research output: Contribution to journalArticleScientificpeer-review

2016

An In Situ Gelling Drug Delivery System for Improved Recovery after Spinal Cord Injury

Liu, D., Jiang, T., Cai, W., Chen, J., Zhang, H., Hietala, S., Santos, H. A., Yin, G. & Fan, J., 22 Jun 2016, In : Advanced Healthcare Materials. 5, 12, p. 1513-1521 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Biodegradable Photothermal and pH Responsive Calcium Carbonate@Phospholipid@Acetalated Dextran Hybrid Platform for Advancing Biomedical Applications

Kong, F., Zhang, H., Zhang, X., Liu, D., Chen, D., Zhang, W., Zhang, L., Santos, H. A. & Hai, M., 13 Sep 2016, In : Advanced Functional Materials. 26, 34, p. 6158-6169 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Development of Innovative Multistage Nanovectors for Cancer Immunotherapy

Fontana, F., Shahbazi, M-A., Liu, D., Zhang, H., Mäkilä, E., Salonen, J., Hirvonen, J. T. & Almeida Santos, H., 30 Sep 2016.

Research output: Conference materialsAbstractResearchpeer-review

Inside Front Cover - Drug Co-Delivery: Biodegradable Photothermal and pH Responsive Calcium Carbonate@Phospholipid@Acetalated Dextran Hybrid Platform for Advancing Biomedical Applications (Adv. Funct. Mater. 34/2016)

Kong, F., Zhang, H., Zhang, X., Liu, D., Chen, D., Zhang, W., Zhang, L., Santos, H. A. & Hai, M., 13 Sep 2016

Research output: Non-textual formDigital or Visual ProductsSolo art productionpeer-review

In vivo dual-delivery of glucagon like peptide -1 (GLP-1) and dipeptidyl peptidase-4 (DPP4) inhibitor through composites prepared by microfluidics for diabetes therapy

Araújo, F., Shrestha, N., João Gomes, M., Herranz Blanco, B., Liu, D., Hirvonen, J. T., L. Granja, P., Almeida Santos, H. & Sarmento, B., 19 Apr 2016, In : Nanoscale. 8, 20, p. 10706-10713 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Platelet lysate-modified porous silicon microparticles for enhanced cell proliferation in wound healing applications

Fontana, F., Mori, M., Riva, F., Mäkilä, E., Liu, D., Salonen, J., Nicoletti, G., Hirvonen, J., Caramella, C. & Santos, H. A., 13 Jan 2016, In : ACS Applied Materials & Interfaces. 8, 1, p. 988-996 9 p.

Research output: Contribution to journalArticleScientificpeer-review

2015

A Versatile and Robust Microfluidic Platform Toward High Throughput Synthesis of Homogeneous Nanoparticles with Tunable Properties

Liu, D., Cito, S., Zhang, Y., Wang, C-F., Sikanen, T. M. & Santos, H. A., 8 Apr 2015, In : Advanced Materials. 27, 14, p. 2298-2304 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Microfluidic Assembly of a Multifunctional Tailorable Composite System Designed for Site Specific Combined Oral Delivery of Peptide Drugs

Araújo, F., Shrestha, N., Shahbazi, M-A., Liu, D., Herranz-Blanco, B., Mäkilä, E. M., Salonen, J. J., Hirvonen, J. T., Granja, P. L., Sarmento, B. & Santos, H. A., Aug 2015, In : ACS Nano. 9, 8, p. 8291-8302 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Microfluidic assisted one-step fabrication of porous silicon@acetalated dextran nanocomposites for precisely controlled combination chemotherapy

Liu, D., Zhang, H., Mäkilä, E., Fan, J., Herranz-Blanco, B., Wang, C-F., Rosa, R., Ribeiro, A. J., Salonen, J., Hirvonen, J. & Santos, H. A., Jan 2015, In : Biomaterials. 39, p. 249-259 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Microfluidic Nanoprecipitation of a Stimuli Responsive Hybrid Nanocomposite for Antitumoral Applications

Herranz Blanco, B., Liu, D., Mäkilä, E. M., Shahbazi, M-A., E, G., Zhang, H., Aseyev, V., Balasubramanian, V., Salonen, J., Hirvonen, J. T. & Almeida Santos, H., 2015, 42nd Annual Meeting & Exposition of the Controlled Release Society. Edinburgh

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientific

On-Chip Self-Assembly of a Smart Hybrid Nanocomposite for Antitumoral Applications

Herranz-Blanco, B., Liu, D., Mäkilä, E., Shahbazi, M-A., Ginestar, E., Zhang, H., Aseyev, V., Balasubramanian, V., Salonen, J., Hirvonen, J. & Santos, H. A., 11 Mar 2015, In : Advanced Functional Materials. 25, 10, p. 1488-1497 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Simple microfluidic approach to fabricate monodisperse hollow microparticles for multidrug delivery

Vasiliauskas, R., Liu, D., Cito, S., Zhang, H., Shahbazi, M-A., Sikanen, T., Mazutis, L. & Santos, H. A., 15 Jul 2015, In : ACS Applied Materials & Interfaces. 7, 27, p. 14822-14832 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Smart porous silicon nanoparticles with polymeric coatings for sequential combination therapy

Xu, W., Thapa, R., Liu, D., Nissinen, T., Granroth, S., Närvänen, A., Suvanto, M., Santos, H. A. & Lehto, V-P., Nov 2015, In : Molecular Pharmaceutics. 12, 11, p. 4038-4047 10 p.

Research output: Contribution to journalArticleScientificpeer-review