Eeva-Liisa Eskelinen

Publications

Research output per year 1985 2020

• 98 Article
• 16 Review Article
• 7 Chapter
• 2 Conference article
• 2 More
  • 1 Anthology or special issue
  • 1 Comment/debate

Research output per year

Research output per year

Search results

• 2020

  Alteration of the late endocytic pathway in Charcot-Marie-Tooth type 2B disease

  Romano, R., Rivellini, C., De Luca, M., Tonlorenzi, R., Beli, R., Manganelli, F., Nolano, M., Santoro, L., Eskelinen, E-L., Previtali, S. C. & Bucci, C., 13 Apr 2020, In : Cellular and Molecular Life Sciences. 22 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

• Altered Basal Autophagy Affects Extracellular Vesicle Release in Cells of Lagotto Romagnolo Dogs With a Variant ATG4D

  Syrjä, P., Palviainen, M., Jokinen, T., Kyöstilä, K., Lohi, H., Roosje, P., Anderegg, L., Leeb, T., Sukura, A. & Eskelinen, E-L., 1 Nov 2020, In : Veterinary Pathology. 57, 6, p. 926-935 10 p., 0300985820959243.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2019

  Autophagy: supporting cellular and organismal homeostasis by self-eating

  Eskelinen, E-L., Jun 2019, In : International Journal of Biochemistry & Cell Biology. 111, p. 1-10 10 p.

  Research output: Contribution to journal › Review Article › peer-review

  Open Access

  File

• Correlative light and electron microscopy of autophagosomes

  Gudmundsson, S. R., Kahlhofer, J., Baylac, N., Kallio, K. A. & Eskelinen, E-L., Jan 2019, Methods in Molecular Biology: Autophagy: Methods and Protocols. Ktistakis, N. & Florey, O. (eds.). Humana press, Vol. 1880. p. 199-209

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Scientific

• Driving next-generation autophagy researchers towards translation (DRIVE), an international PhD training program on autophagy

  Kraft, C., Boya, P., Codogno, P., Elazar, Z., Eskelinen, E-L., Farres, J., Kirkin, V., Jungbluth, H., Martinez, A., Pless, O., Primard, C., Proikas-Cezanne, T., Simonsen, A. & Reggiori, F., 1 Feb 2019, In : Autophagy. 15, 2, p. 347-351 5 p.

  Research output: Contribution to journal › Comment/debate › Scientific

  Open Access

  File

• ER-Targeted Beclin 1 Supports Autophagosome Biogenesis in the Absence of ULK1 and ULK2 Kinases

  Anwar, T., Liu, X., Suntio, T., Marjamäki, A., Biazik, J., Chan, E. Y. W., Varjosalo, M. & Eskelinen, E-L., 17 May 2019, In : Cells. 8, 5, 24 p., 475.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Mammalian Atg8 proteins regulate lysosome and autolysosome biogenesis through SNAREs

  Gu, Y., Abudu, Y. P., Kumar, S., Bissa, B., Choi, S. W., Jia, J., Lazarou, M., Eskelinen, E-L., Johansen, T. & Deretic, V., 15 Nov 2019, In : EMBO Journal. 38, 22, 22 p., 101994.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

• Selective autophagy of mitochondria on a ubiquitin-endoplasmic reticulum platform

  Zachari, M., Gudmundsson, S. R., Li, Z., Manifava, M., Shah, R., Smith, M., Stronge, J., Karanasios, E., Piunti, C., Kishi-Itakura, C., Vihinen, H., Jokitalo, E., Guan, J-L., Buss, F., Smith, A. M., Walker, S. A., Eskelinen, E-L. & Ktistakis, N. T., 9 Sep 2019, In : Developmental Cell. 50, 5, p. 627-+ 22 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2018

  Alterations of autophagy in the peripheral neuropathy Charcot-Marie-Tooth type 2B

  Colecchia, D., Stasi, M., Leonardi, M., Manganelli, F., Nolano, M., Veneziani, BM., Santoro, L., Eskelinen, E-L., Chiariello, M. & Bucci, C., 2018, In : Autophagy. 14, 6, p. 930-941 12 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Deficit in PINK1-PARKIN mediated mitochondrial autophagy at late stages of dystrophic cardiomyopathy

  Kang, C., Badr, M. A., Kyrychenko, V., Eskelinen, E-L. & Shirokova, N., 1 Jan 2018, In : Cardiovascular Research. 114, 1, p. 90-102 13 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• GIMAP6 is required for T cell maintenance and efficient autophagy in mice

  Pascall, JC., Webb, LMC., Eskelinen, E-L., Innocentin, S., Attaf-Bouabdallah, N. & Butcher, GW., 2 May 2018, In : PLoS One. 13, 5, p. e0196504 30 p., 0196504.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis

  Carroll, B., Otten, EG., Manni, D., Stefanatos, R., Menzies, FM., Smith, GR., Jurk, D., Kenneth, N., Wilkinson, S., Passos, JF., Attems, J., Veal, EA., Teyssou, E., Seilhean, D., Millecamps, S., Eskelinen, E-L., Bronowska, AK., Rubinsztein, DC., Sanz, A. & Korolchuk, VI., 17 Jan 2018, In : Nature Communications. 9, 1, p. 256 11 p., 256.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Roles for RAB24 in autophagy and disease

  Ylä-Anttila, P. & Eskelinen, E-L., 4 Mar 2018, In : Small GTPases. 9, 1-2, p. 1-9

  Research output: Contribution to journal › Review Article › peer-review

  Open Access

  File

• Vacuole membrane protein 1 marks endoplasmic reticulum subdomains enriched in phospholipid synthesizing enzymes and is required for phosphoinositide distribution

  Tabara, LC., Vicente, JJ., Richmond, J., Eskelinen, E-L., Vincent, O. & Escalante, R., Aug 2018, In : Traffic. 19, 8, p. 624-638 15 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2017

  2BC Non-Structural Protein of Enterovirus A71 Interacts with SNARE Proteins to Trigger Autolysosome Formation

  Lai, J. K. F., Sam, I-C., Verlhac, P., Baguet, J., Eskelinen, E-L., Faure, M. & Chan, Y. F., Jul 2017, In : Viruses-Basel. 9, 7, 15 p., 169.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Basal Autophagy is altered in Lagotto Romagnolo Dogs with an ATG4D mutation

  Syrjä, P., Anwar, T., Pääkkönen, T., Kyöstilä, K., Hultin Jäderlund, K., Cozzi, F., Rohdin, C., Hahn, K., Wohlsein, P., Baumgärtner, W., Henke, D., Oevermann, A., Sukura, A., Leeb, T., Lohi, H. & Eskelinen, E-L., Nov 2017, In : Veterinary Pathology. 54, 6, p. 953-963 11 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Calpain mobilizes Atg9/Bif-1 vesicles from Golgi stacks upon autophagy induction by thapsigargin

  Marcassa, E., Raimondi, M., Anwar, T., Eskelinen, E-L., Myers, M. P., Triolo, G., Schneider, C. & Demarchi, F., 15 May 2017, In : Biology open. 6, p. 551-562

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Depletion of TM6SF2 disturbs membrane lipid composition and dynamics in HuH7 hepatoma cells.

  Ruhanen, H., Haridas, P. A. N., Eskelinen, E-L., Eriksson, O., Olkkonen, V. M. & Käkelä, R., May 2017, In : Biochimica and Biophysica Acta. Molecular and Cell Biology of Lipids. 1862, 7, p. 676-685 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Disruption of the vacuolar-type H+-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes

  Kissing, S., Rudnik, S., Damme, M., Luellmann-Rauch, R., Ichihara, A., Kornak, U., Eskelinen, E-L., Jabs, S., Heeren, J., De Brabander, J. K., Haas, A. & Saftig, P., 2017, In : Autophagy. 13, 4, p. 670-685 16 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Molecular definitions of autophagy and related processes

  Galluzzi, L., Baehrecke, E. H., Ballabio, A., Boya, P., Pedro, J. M. B-S., Cecconi, F., Choi, A. M., Chu, C. T., Codogno, P., Isabel Colombo, M., Maria Cuervo, A., Debnath, J., Deretic, V., Dikic, I., Eskelinen, E-L., Fimia, G. M., Fulda, S., Gewirtz, D. A., Green, D. R., Hansen, M. & 34 others, Harper, J. W., Jaattela, M., Johansen, T., Juhasz, G., Kimmelman, A. C., Kraft, C., Ktistakis, N. T., Kumar, S., Levine, B., Lopez-Otin, C., Madeo, F., Martens, S., Martinez, J., Melendez, A., Mizushima, N., Munz, C., Murphy, L. O., Penninger, J. M., Piacentini, M., Reggiori, F., Rubinsztein, D. C., Ryan, K. M., Santambrogio, L., Scorrano, L., Simon, A. K., Simon, H-U., Simonsen, A., Tavernarakis, N., Tooze, S. A., Yoshimori, T., Yuan, J., Yue, Z., Zhong, Q. & Kroemer, G., 3 Jul 2017, In : EMBO Journal. 36, 13, p. 1811-1836 26 p.

  Research output: Contribution to journal › Review Article › peer-review

  Open Access

• Parkinsonin tauti - solujen kierrätyskeskus epäkunnossa?

  Eskelinen, E-L. & Holmberg-Still, C. I., Aug 2017, In : Parkinson-postia. 3, p. 24-25

  Research output: Contribution to journal › Article › General public

• Ultrastructural characterization of phagophores using electron tomography on cryoimmobilized and freeze substituted samples: Ultrastructure of autophagosomes

  Biazik, J., Vihinen, H., Jokitalo, E. S. & Eskelinen, E-L., 2017, In : Methods in Enzymology. 587, p. 331-349 19 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2016

  Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

  Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Eskelinen, E-L., Hulmi, J. J., Korhonen, L., Lindholm, D., Screen, M., Stratoulias, V. & Zughaier, S. M., 21 Jan 2016, In : Autophagy. 12, 1, p. 1-222

  Research output: Contribution to journal › Article › Scientific › peer-review

• Lääketieteen Nobelin palkinto autofagian tutkijalle

  Kaarniranta, K., Meri, S. & Eskelinen, E-L., Nov 2016, In : Duodecim. 132, 22, p. 2141-2144 4 p.

  Research output: Contribution to journal › Article › Professional

• TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation

  Mandell, M. A., Jain, A., Kumar, S., Castleman, M. J., Anwar, T., Eskelinen, E-L., Johansen, T., Prerekis, R. & Deretic, V., 1 Oct 2016, In : Journal of Cell Science. 129, p. 3562-3573

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2015

  Autophagy in neuronal cells: general principles and physiological and pathological functions

  Damme, M., Suntio, T., Saftig, P. & Eskelinen, E-L., Feb 2015, In : Acta Neuropathologica. 129, 3, p. 337-362 26 p.

  Research output: Contribution to journal › Review Article › peer-review

• Foreword to Volume 7 of the book series Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection and Aging. Hayat MA (ed)

  Eskelinen, E-L., 2015, Foreword to Volume 4 of the series Autophagy. Cancer, other pathologies, inflammation, immunity, infection, and aging. Hayat MA (ed): Mitophagy. Elsevier Academic Press, Vol. Volume 7.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Scientific

• RAB24 facilitates clearance of autophagic compartments during basal conditions

  Ylä-Anttila, P. H., Mikkonen, E., Happonen, K. E., Holland, P., Ueno, T., Simonsen, A. & Eskelinen, E-L., Oct 2015, In : Autophagy. 11, 10, p. 1833-1848 16 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Role of endoplasmic reticulum in the formation of phagophores/autophagosomes: Three-dimensional morphology

  Biazik, J., Vihinen, H., Jokitalo, E. & Eskelinen, E-L., 2015, Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection and Aging: Volume 7: Role of Autophagy in Therapeutic Applications. Hayat, MA. (ed.). USA: Elsevier Academic Press, Vol. Volume 7. p. 57–68 12 p. Chapter 2

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Scientific

• The versatile electron microscope: an ultrastructural overview of autophagy

  Biazik, J., Vihinen, H., Anwar, T., Jokitalo, E. & Eskelinen, E-L., 2015, In : Methods. 75, p. 44-53 10 p.

  Research output: Contribution to journal › Review Article › peer-review

  Open Access

  File

• Ultrastructural relationship of the phagophore with surrounding organelles

  Biazik, J., Yla-Anttila, P., Vihinen, H., Jokitalo, E. & Eskelinen, E-L., Mar 2015, In : Autophagy. 11, 3, p. 439-451 13 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access
• 2014

  A non-conserved miRNA regulates lysosomal function and impacts on a human lysosomal storage disorder

  Frankel, L. B., Di Malta, C., Wen, J., Eskelinen, E-L., Ballabio, A. & Lund, A. H., Dec 2014, In : Nature Communications. 5, 11 p., 5840.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Autophagosomes, phagosomes, autolysosomes, phagolysosomes, autophagolysosome. Wait, I’m confused

  Klionsky, D. J., Eskelinen, E-L. & Deretic, V., 17 Mar 2014, In : Autophagy. 10, 4, p. 549-551 3 p.

  Research output: Contribution to journal › Article › Scientific

• BECN1 is involved in the initiation of mitophagy: It facilitates PARK2 translocation to mitochondria

  Choubey, V., Cagalinec, M., Liiv, J., Safiulina, D., Hickey, M. A., Kuum, M., Liiv, M., Anwar, T., Eskelinen, E-L. & Kaasik, A., 17 Apr 2014, In : Autophagy. 10, 6, p. 1105-1119 15 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Do mitochondria donate membrane to form autophagosomes or undergo remodeling to form mitochondrial spheroids?

  Xing-Ding, W. & Eskelinen, E-L., 2014, In : Cell & bioscience. 4, 2 p., 65.

  Research output: Contribution to journal › Article › Scientific

• Quantitative Proteomics of Extracellular Vesicles Released from Human Monocyte-Derived Macrophages upon beta-Glucan Stimulation

  Cypryk, W., Öhman, T., Eskelinen, E-L., Matikainen, S. & Nyman, T. A., May 2014, In : Journal of Proteome Research. 13, 5, p. 2468-2477 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Syväsuuntautunut suhtautuminen oppimiseen: Mitä opettaja voi tehdä sen edistämiseksi?

  Eskelinen, E-L., Peltoniemi, M. & Roine, E., 21 Oct 2014, In : Teaching in Life Sciences: Current practices and development. 1, Fall, p. 1-16 16 p.

  Research output: Contribution to journal › Article › Professional

• The vacuole versus the lysosome When size matters

  Klionsky, D. J. & Eskelinen, E-L., 1 Feb 2014, In : Autophagy. 10, 2, p. 185-187 3 p.

  Research output: Contribution to journal › Article › Scientific
• 2013

  Autophagy researchers: Eeva-Liisa Eskelinen

  Eskelinen, E-L., 2013, In : Autophagy. 9, 10, p. 1 1 p.

  Research output: Contribution to journal › Article › Scientific

• Beclin 2 Functions in Autophagy, Degradation of G Protein-Coupled Receptors, and Metabolism

  He, C., Wei, Y., Sun, K., Li, B., Dong, X., Zou, Z., Liu, Y., Kinch, L. N., Khan, S., Sinha, S., Xavier, R. J., Grishin, N. V., Xiao, G., Eskelinen, E-L., Scherer, P. E., Whistler, J. L. & Levine, B., 29 Aug 2013, In : Cell. 154, 5, p. 1085-1099 15 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain

  Schneppenheim, J., Dressel, R., Hüttl, S., Lüllmann-Rauch, R., Engelke, M., Dittmann, K., Wienands, J., Eskelinen, E-L., Hermans-Borgmeyer, I., Fluhrer, R., Saftig, P. & Schröder, B., 14 Jan 2013, In : Journal of Experimental Medicine. 210, 1, p. 41-58 18 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2012

  Electron microscopic analysis of a spherical mitochondrial structure

  Ding, W-X., Li, M., Biazik, J., Morgan, D. G., Guo, F., Ni, H-M., Goheen, M., Eskelinen, E-L. & Yin, X-M., 2012, In : Journal of Biological Chemistry. 287, 50, p. 42373-42378 6 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Guidelines for the use and interpretation of assays for monitoring autophagy

  Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Eskelinen, E-L. & other authors, Apr 2012, In : Autophagy. 8, 4, p. 445-544 100 p.

  Research output: Contribution to journal › Review Article › peer-review

• Parkin and mitofusins reciprocally regulate mitophagy and mitochondrial spheroid formation

  Ding, W-X., Guo, F., Ni, H-M., Bockus, A., Manley, S., Stolz, D. B., Eskelinen, E-L., Jaeschke, H. & Yin, X-M., 2012, In : Journal of Biological Chemistry. 287, 50, p. 42379-42388 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2011

  A comprehensive glossary of autophagy-related molecules and processes (2nd edition)

  Klionsky, D. J., Baehrecke, E. H., Brumell, J. H., Chu, C. T., Codogno, P., Cuervo, A. M., Debnath, J., Deretic, V., Elazar, Z., Eskelinen, E-L., Finkbeiner, S., Fueyo-Margareto, J., Gewirtz, D., Jäättelä, M., Kroemer, G., Levine, B., Melia, T. J., Mizushima, N., Rubinsztein, D. C., Simonsen, A. & 3 others, Thorburn, A., Thumm, M. & Tooze, S. A., 2011, In : Autophagy. 7, 11, p. 1273-1294 22 p.

  Research output: Contribution to journal › Review Article › peer-review

• Cheating on ubiquitin with Atg8

  Krick, R., Bremer, S., Welter, E., Eskelinen, E-L. & Thumm, M., 2011, In : Autophagy. 7, p. 250-251 2 p.

  Research output: Contribution to journal › Article › Scientific

• Double membranes vs. lipid bilayers, and their significance for correct identification of macroautophagic structures.

  Eskelinen, E-L. & Kovacs, A. L., Sep 2011, In : Autophagy. 7, 9, p. 931-932 2 p.

  Research output: Contribution to journal › Article › Scientific

• Role for LAMP-2 in endosomal cholesterol transport

  Schneede, A., Schmidt, CK., Hölttä-Vuori, M., Heeren, J., Willenborg, M., Blanz, J., Domanskyy, M., Breiden, B., Brodesser, S., Landgrebe, J., Sandhoff, K., Ikonen, E., Saftig, P. & Eskelinen, E-L., 2011, In : Journal of Cellular and Molecular Medicine. 15, 2, p. 280-295 16 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Seeing is believing: The impact of electron microscopy on autophagy research

  Eskelinen, E-L., Reggiori, F., Baba, M., Kovács, A. L. & Seglen, P. O., Sep 2011, In : Autophagy. 7, 9, p. 935-956 22 p.

  Research output: Contribution to journal › Review Article › peer-review

• The dual role of autophagy in cancer

  Eskelinen, E-L., Aug 2011, In : Current Opinion in Pharmacology. 11, 4, p. 294-300 7 p.

  Research output: Contribution to journal › Article › Scientific