Research output per year
Research output per year
Personal profile
Fields of Science
- 317 Pharmacy
- Medicinal Chemistry
- Pharmaceutical Chemistry
- 116 Chemical sciences
- Medicinal Chemistry
- Organic Chemistry
International and National Collaboration
Publications and projects within past five years.
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5-Aminothiazoles Reveal a New Ligand-Binding Site on Prolyl Oligopeptidase Which is Important for Modulation of Its Protein-Protein Interaction-Derived Functions
Pätsi, H. T., Kilpeläinen, T. P., Jumppanen, M., Uhari-Väänänen, J., Wielendaele, P. V., De Lorenzo, F., Cui, H., Auno, S., Saharinen, J., Seppälä, E., Sipari, N., Savinainen, J., De Meester, I., Lambeir, A. M., Lahtela-Kakkonen, M., Myöhänen, T. T. & Wallén, E. A. A., 2024, In: Journal of Medicinal Chemistry. 67, 7, p. 5421–5436Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Azulene as a biphenyl mimetic in orexin/hypocretin receptor agonists
Leino, T. O., Turku, A., Urvas, L., Adhikari, K., Oksanen, J., Steynen, Y., Yli-Kauhaluoma, J., Xhaard, H., Kukkonen, J. P. & Wallén, E. A. A., 6 Jun 2023, In: Bioorganic & Medicinal Chemistry. 88-89, 9 p., 117325.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Nonpeptidic Oxazole-Based Prolyl Oligopeptidase Ligands with Disease-Modifying Effects on alpha-Synuclein Mouse Models of Parkinson's Disease
Kilpelainen, T. P., Patsi, H. T., Svarcbahs, R., Julku, U. H., Eteläinen, T. S., Cui, H., Auno, S., Sipari, N., Norrbacka, S., Leino, T. O., Jäntti, M., Myöhänen, T. T. & Wallen, E. A. A., 29 May 2023, In: Journal of Medicinal Chemistry. 66, 11, p. 7475-7496 22 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
The azulene scaffold from a medicinal chemist's perspective: Physicochemical and in vitro parameters relevant for drug discovery
Leino, T., Sieger, P., Yli-Kauhaluoma, J., Wallén, E. A. A. & Kley, J. T., 5 Jul 2022, In: European Journal of Medicinal Chemistry. 237, 12 p., 114374.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2-Imidazole as a Substitute for the Electrophilic Group Gives Highly Potent Prolyl Oligopeptidase Inhibitors
Pätsi, H. T., Kilpeläinen, T. P., Auno, S., Dillemuth, P. M. J., Arja, K., Lahtela-Kakkonen, M. K., Myöhänen, T. T. & Wallen, E. A. A., 14 Oct 2021, In: ACS Medicinal Chemistry Letters. 12, 10, p. 1578-1584 7 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
Prizes
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Teacher Award for “Distinguished and student-centered teaching”
Wallen, E. (Recipient), 11 Feb 2011
Prize: Prizes and awards
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Young Scientist Reward for Outstanding Doctoral Study
Wallen, E. (Recipient), 7 May 2004
Prize: Prizes and awards
Activities
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Novel prolyl oligopeptidase ligands on neurodegenerative diseases
Myöhänen, T. (Supervisor) & Wallén, E. A. A. (Supervisor)
2017Activity: Examination types › Supervisor or co-supervisor of doctoral thesis
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Pre-examination of doctoral thesis (Jayendra Patel)
Wallen, E. (Pre-examiner)
19 Sept 2015Activity: Examination types › Pre-examiner of doctoral thesis
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Pre-examination of doctoral thesis (Christopher Lood)
Wallen, E. (Pre-examiner)
3 Jul 2015Activity: Examination types › Pre-examiner of doctoral thesis
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Federation of Finnish Learned Societies (External organisation)
Wallen, E. (Assessment)
2014 → …Activity: Membership types › Membership or other role in national/international committee, council, board
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Pre-examination of doctoral thesis (Liwei Liu)
Wallen, E. (Pre-examiner)
24 Oct 2014Activity: Examination types › Pre-examiner of doctoral thesis