Research output per year
Research output per year
Personal profile
Fields of Science
- 317 Pharmacy
International and National Collaboration
Publications and projects within past five years.
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5-Aminothiazoles Reveal a New Ligand-Binding Site on Prolyl Oligopeptidase Which is Important for Modulation of Its Protein-Protein Interaction-Derived Functions
Pätsi, H. T., Kilpeläinen, T. P., Jumppanen, M., Uhari-Väänänen, J., Wielendaele, P. V., De Lorenzo, F., Cui, H., Auno, S., Saharinen, J., Seppälä, E., Sipari, N., Savinainen, J., De Meester, I., Lambeir, A. M., Lahtela-Kakkonen, M., Myöhänen, T. T. & Wallén, E. A. A., 2024, In: Journal of Medicinal Chemistry.Research output: Contribution to journal › Article › Scientific › peer-review
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A prolyl oligopeptidase inhibitor reduces tau pathology in cellular models and in mice with tauopathy
Eteläinen, T. S., Silva, M. C., Uhari-Väänänen, J. K., De Lorenzo, F., Jäntti, M. H., Cui, H., Chavero-Pieres, M., Kilpeläinen, T., Mechtler, C., Svarcbahs, R., Seppälä, E., Savinainen, J. R., Puris, E., Fricker, G., Gynther, M., Julku, U. H., Huttunen, H. J., Haggarty, S. J. & Myöhänen, T., 12 Apr 2023, In: Science translational medicine. 15, 691, eabq2915.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
CDNF rescues motor neurons in models of amyotrophic lateral sclerosis by targeting endoplasmic reticulum stress
De Lorenzo, F., Lüningschrör, P., Nam, J., Beckett, L., Pilotto, F., Galli, E., Lindholm, P., von Collenberg, C. R., Mungwa, S. T., Jablonka, S., Kauder, J., Thau-Habermann, N., Petri, S., Lindholm, D., Saxena, S., Sendtner, M., Saarma, M. & Voutilainen, M. H., 1 Sept 2023, In: Brain : a journal of neurology. 146, 9, p. 3783–3799 17 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Prolyylioligopeptidaasin estäjistä apua muistisairauksien pysäyttämiseen?
Eteläinen, T. S., Silva, M. C., Uhari-Väänänen, J. K., De Lorenzo, F., Jäntti, M. H., Cui, H., Chavero-Pieres, M., Kilpeläinen, T., Mechtler, C., Svarcbahs, R., Seppälä, E., Savinainen, J. R., Puris, E., Fricker, G., Gynther, M., Julku, U. H., Huttunen, H. J., Haggarty, S. J. & Myöhänen, T., 2023, In: Duodecim. 139, 11, p. 941 1 p.Research output: Contribution to journal › Comment/debate › Professional
Open AccessFile -
Removal of proteinase K resistant alpha Syn species does not correlate with cell survival in a virus vector-based Parkinson's disease mouse model
Eteläinen, T. S., Kilpeläinen, T. P., Ignatius, A., Auno, S., De Lorenzo, F., Uhari-Väänänen, J. K., Julku, U. H. & Myöhänen, T. T., 1 Nov 2022, In: Neuropharmacology. 218, 15 p., 109213.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
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Mechanisms of constitutive vs. adaptive immune resistance of treatment persistent residual tumor cells
Mustjoki, S. (Project manager), De Lorenzo, F. (Participant), Decombis, S. (Participant), Fred, S. M. (Participant) & Wartiovaara, L. T. (Participant)
Suomen Akatemia Projektilaskutus
01/01/2023 → 31/12/2027
Project: Research Council of Finland: Bilateral partnerships, joint calls
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JAES 2023-2026 MUSTJOKI SATU Discovery o
Mustjoki, S. (Project manager), Awad, S. (Participant), Bouhlal, J. O. V. (Participant), De Lorenzo, F. (Participant), Dufva, O. (Participant), Fred, S. M. (Participant), Gandolfi, S. (Participant), Huuhtanen, J. (Participant), Häkkinen, A.-E. A. (Participant), Jokinen, E. A. (Participant), Kasanen, T. S. (Participant), Laajala, E. J. (Participant), Lundgren, S. (Participant), Nygren, P. J. (Participant), Peltonen, K. (Participant), Sirc, N. (Participant) & Wartiovaara, L. T. (Participant)
01/12/2022 → 31/12/2026
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
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CDNF- A novel drug therapy for treatment of ALS
Voutilainen, M. (Project manager), De Lorenzo, F. (Participant) & Beckett, L. (Participant)
01/01/2017 → 31/12/2019
Project: University of Helsinki Three-Year Research Project
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CDNF ja MANF amyotrofisen lateraaliskleroosin geneettisissä malleissa
Voutilainen, M. (Project manager), De Lorenzo, F. (Participant) & Stepanova, P. (Participant)
01/09/2014 → 31/08/2017
Project: Research project
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M.Voutilainen Jane ja Aatos Erkon säätiö
Voutilainen, M. (Project manager), De Lorenzo, F. (Participant) & Stepanova, P. (Participant)
01/10/2013 → 30/09/2016
Project: Research project
Activities
- 1 Other
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Patient-researcher meetup, hematological cancers
Liljeström, M. (Participant), Mustjoki, S. (Participant), Kontro, M. (Participant), Heckman, C. (Participant), Porkka, K. (Participant), Klievink, J. (Participant), Decombis, S. (Participant), Miettinen, J. (Participant), De Lorenzo, F. (Participant) & Suvela, M. (Participant)
9 Sept 2024Activity: Other activity types › Other