Research output per year
Research output per year
Personal profile
Fields of Science
- 317 Pharmacy
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Novel PREP ligand, HUP-46, ameliorates behavioral deficits in an alpha-synuclein based Parkinson's disease model
Kilpeläinen, T., Yang, R., Toivio, J., Eteläinen, T., De Lorenzo, F., Fastré, B., Zuo, C., Uhari-Väänänen, J. K., Julku, U., Cui, H. & Myöhänen, T. T., Mar 2026, In: Experimental Neurology. 397, 13 p., 115593.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
A prolyl oligopeptidase ligand blocks memory deficit in a repeated mild traumatic brain injury model
Uhari-Väänänen, J., Eteläinen, T., Zuo, C., De Lorenzo, F., Kilpeläinen, T. & Myöhänen, T. T., Dec 2025, In: Experimental Neurology. 394, 14 p., 115454.Research output: Contribution to journal › Article › Scientific › peer-review
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GDNF reduces fibril-induced early-stage alpha-synuclein pathology after delivery of 20S proteasome inhibitor lactacystin
Er, S., Parkkinen, I., Trepczyk, K., Seelbach, A., Pasculli, M. S., De Lorenzo, F., Luk, K., Jankowska, E., Chmielarz, P., Domanskyi, A. & Airavaara, M., 1 May 2025, In: European Journal of Pharmaceutical Sciences. 208, 11 p., 107048.Research output: Contribution to journal › Article › Scientific › peer-review
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5-Aminothiazoles Reveal a New Ligand-Binding Site on Prolyl Oligopeptidase Which is Important for Modulation of Its Protein-Protein Interaction-Derived Functions
Pätsi, H. T., Kilpeläinen, T. P., Jumppanen, M., Uhari-Väänänen, J., Wielendaele, P. V., De Lorenzo, F., Cui, H., Auno, S., Saharinen, J., Seppälä, E., Sipari, N., Savinainen, J., De Meester, I., Lambeir, A. M., Lahtela-Kakkonen, M., Myöhänen, T. T. & Wallén, E. A. A., 2024, In: Journal of Medicinal Chemistry. 67, 7, p. 5421–5436Research output: Contribution to journal › Article › Scientific › peer-review
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A prolyl oligopeptidase inhibitor reduces tau pathology in cellular models and in mice with tauopathy
Eteläinen, T. S., Silva, M. C., Uhari-Väänänen, J. K., De Lorenzo, F., Jäntti, M. H., Cui, H., Chavero-Pieres, M., Kilpeläinen, T., Mechtler, C., Svarcbahs, R., Seppälä, E., Savinainen, J. R., Puris, E., Fricker, G., Gynther, M., Julku, U. H., Huttunen, H. J., Haggarty, S. J. & Myöhänen, T., 12 Apr 2023, In: Science translational medicine. 15, 691, eabq2915.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
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Mechanisms of constitutive vs. adaptive immune resistance of treatment persistent residual tumor cells
Mustjoki, S. (Project manager), Ciboddo, M. (Participant), De Lorenzo, F. (Participant), Decombis, S. (Participant), Fred, S. M. (Participant) & Wartiovaara, L. T. (Participant)
Suomen Akatemia Projektilaskutus
01/01/2023 → 31/12/2027
Project: Research Council of Finland: Bilateral partnerships, joint calls
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JAES 2023-2026 MUSTJOKI SATU Discovery o
Mustjoki, S. (Project manager), Awad, S. (Participant), Bouhlal, J. O. V. (Participant), De Lorenzo, F. (Participant), Dufva, O. (Participant), Duàn, H. (Participant), Fred, S. M. (Participant), Gandolfi, S. (Participant), Huuhtanen, J. (Participant), Häkkinen, A.-E. A. (Participant), Jokinen, E. A. (Participant), Kasanen, T. S. (Participant), Kärkkäinen, K. M. E. (Participant), Laajala, E. J. (Participant), Lundgren, S. (Participant), Nygren, P. J. (Participant), Peltonen, K. (Participant), Sirc, N. (Participant), Vo, D. N. (Participant) & Wartiovaara, L. T. (Participant)
01/12/2022 → 31/12/2026
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
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CDNF- A novel drug therapy for treatment of ALS
Voutilainen, M. (Project manager), De Lorenzo, F. (Participant) & Beckett, L. (Participant)
01/01/2017 → 31/12/2019
Project: University of Helsinki Three-Year Research Project
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CDNF ja MANF amyotrofisen lateraaliskleroosin geneettisissä malleissa
Voutilainen, M. (Project manager), De Lorenzo, F. (Participant) & Stepanova, P. (Participant)
01/09/2014 → 31/08/2017
Project: Research project
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M.Voutilainen Jane ja Aatos Erkon säätiö
Voutilainen, M. (Project manager), De Lorenzo, F. (Participant) & Stepanova, P. (Participant)
01/10/2013 → 30/09/2016
Project: Research project
Activities
- 1 Other
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Patient-researcher meetup, hematological cancers
Liljeström, M. (Participant), Mustjoki, S. (Participant), Kontro, M. (Participant), Heckman, C. (Participant), Porkka, K. (Participant), Klievink, J. (Participant), Decombis, S. (Participant), Miettinen, J. (Participant), De Lorenzo, F. (Participant) & Suvela, M. (Participant)
9 Sept 2024Activity: Other activity types › Other