Gretchen Repasky

  • PL 20 (Tukholmankatu 8)

    00014

    Finland

19942018
If you made any changes in Pure these will be visible here soon.

Personal profile

Curriculum vitae

POSITIONS AND ROLES OF SIGNIFICANCE

Senior Researcher, Research Training Coordinator, Institute for Molecular Medicine, Finland, University of Helsinki, Finland (2010–present)

Doctoral Program Coordinator, Doctoral Programs in Biomedicine and Oral Sciences, Doctoral School in Health Sciences, University of Helsinki, Finland (2014–2015)

Interim RNAi Unit Coordinator, FIMM Technology Centre, Institute for Molecular Medicine, Finland, University of Helsinki, Finland (2010–2011)

Assistant Professor, Biology and Chemistry/Physics Departments, Birmingham-Southern College, Birmingham, AL USA (2006–2009)

Assistant Professor of Biochemistry, Chemistry Department, The Colorado College, Colorado Springs, CO USA (2004–2006)

Post-doctoral Research Fellow, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC USA (2000–2004)

Adjunct Professor, Department of Biology, Meredith College, Raleigh, NC USA (2003–2004) 

Course Instructor, Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC USA (2001-2003) 

Course Instructor, Carolina College for Lifelong Learning, General Alumni Association, University of North Carolina at Chapel Hill, Chapel Hill, NC USA (2002)

Teaching Assistant, Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC USA (2001-2003)

Summer Research Intern, Drug Disposition and Metabolism Unit, Analytical Chemistry, Zeneca Pharmaceuticals, Wilmington, DE USA (1992, 1993)  

 

PROGRAMS MANAGED

FIMM Doctoral Training Committee, Institute for Molecular Medicine, Finland, University of Helsinki, Finland (2015-present)

FIMMPOD, FIMM Postdoctoral and Senior Researcher Professional Development Program, Institute for Molecular Medicine, Finland, University of Helsinki, Finland (2014-present)

Doctoral Programs in Biomedicine and Oral Sciences, Doctoral School in Health Sciences, University of Helsinki, Finland (2014–2015)

FIMM-EMBL International PhD Program, Institute for Molecular Medicine, Finland, University of Helsinki, Finland (2010-present)

 

PROJECTS 

WikiDruget, Institute for Molecular Medicine, Finland, University of Helsinki, Finland(2015-present) 

Pfizer IIR Project, Studies of axitinib and axitinib drug combinations as BCR-ABL1 T315I-selective therapies for use in drug-resistant CML and Ph+ ALL, Institute for Molecular Medicine, Finland, University of Helsinki, Finland (2014-2016)

EU-OPENSCREEN, ESFRI Project, Institute for Molecular Medicine, Finland, University of Helsinki, Finland (2011–2013)

LIBRA/Leading innovative measures to reach gender balance in research activities, Horizon 2020 (2015-2018)

Research Corporation CC6677, Cottrell College Science Award:  Biochemical Role of the PEDF Tumor Suppressor in Ras-Mediated Pancreatic Oncogenesis (2007-2009)

The Colorado College, Natural Science Faculty Research & Development Funds and Faculty-Student Collaborative Research Awards:  The Biochemical Role of the Cyclooxygenase-2 Enzyme:  Implications in the Development of Colorectal Cancer (2005-2006) and Biochemical Role of the PEDF Tumor Suppressor in Ras-Mediated Pancreatic Oncogenesis (2005)

Life Sciences Research Foundation, Merck Fellow:  The Mechanism of Activation and Role of Cyclooxygenase-2 in Ras-Mediated Transformation (2001-2004)

National Institutes of Health, Post-Doctoral NIH Training Grant, Lineberger Post-Doctoral Fellowship Award (2000-2001)

National Institutes of Health, Pre-Doctoral NIH Training Grant, Cell and Molecular Biology Training Program (1994-1995)

 

PUBLICATIONS

Note:  Surname change from Murphy to Repasky in 2004

Education information

Doctor of Philosophy, Cell and Molecular Biology, New York University, Graduate School of Arts and Sciences, New York, NY USA (1999)

Bachelor of Science, Biochemistry, Lehigh University, College of Engineering and Applied Sciences, Bethlehem, PA USA (1994)

Education/Academic qualification

Biochemistry, Molecular and Cellular Biology, Doctor of Philosophy, New York University Langone Medical Center, University of New York, New York, USA

19951999

Biochemistry, Bachelor of Science (USA), Lehigh University, College of Engineering and Applied Sciences, Bethlehem, PA USA

19901994

Cancer cell biology, Postdoctoral fellowship

20002004

Fields of Science

  • 1182 Biochemistry, cell and molecular biology
  • cancer cell biology
  • 3111 Biomedicine
  • 3122 Cancers

International and National Collaboration Publications and projects within past five years.

Publications 1994 2018

Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions

Tang, J., Tanoli, Z-R., Ravikumar, B., Alam, Z., Rebane, A., Vähä-Koskela, M., Peddinti, G., van Adrichem, A. J., Wakkinen, J., Jaiswal, A., Karjalainen, E., Gautam, P., He, L., Parri, E., Khan, S., Gupta, A., Ali, M., Yetukuri, L., Gustavsson, A-L., Seashore-Ludlow, B. & 6 othersHersey, A., Leach, A. R., Overington, J. P., Repasky, G., Wennerberg, K. & Aittokallio, T., 15 Feb 2018, In : Cell chemical biology. 25, 2, p. 224-+ 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Molecular Changes During Acute Myeloid Leukemia (AML) Evolution and Identification of Novel Treatment Strategies Through Molecular Stratification

Karjalainen, E. & Repasky, G. A., 2016, MOLECULAR AND CELLULAR CHANGES IN THE CANCER CELL. Pruitt, K. (ed.). ACADEMIC PRESS INC ELSEVIER SCIENCE, p. 383-436 54 p. (Progress in Molecular Biology and Translational Science; vol. 144).

Research output: Chapter in Book/Report/Conference proceedingChapterScientific

Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation

Pemovska, T., Johnson, E., Kontro, M., Repasky, G. A., Chen, J., Wells, P., Cronin, C. N., McTigue, M., Kallioniemi, O., Porkka, K., Murray, B. W. & Wennerberg, K., 5 Mar 2015, In : Nature. 519, 7541, p. 102-U225 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Discovery of MINC1, a GTPase-Activating Protein Small Molecule Inhibitor, Targeting MgcRacGAP

van Adrichem, A. J., Fagerholm, A., Turunen, L., Lehto, A., Saarela, J., Koskinen, A., Repasky, G. A. & Wennerberg, K., 2015, In : Combinatorial Chemistry & High Throughput Screening. 18, 1, p. 3-17 15 p.

Research output: Contribution to journalArticleScientificpeer-review

The higher frequency of IgA deficiency among Swedish twins is not explained by HLA haplotypes

Frankowiack, M., Kovanen, R-M., Repasky, G. A., Lim, C. K., Song, C., Pedersen, N. L. & Hammarstom, L., 2015, In : Genes and Immunity. 16, 3, p. 199-205 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Projects 2010 2014

Activities 1994 2015

Evaluation committee (External organisation)

Gretchen Repasky (Chair)
26 Nov 2015

Activity: Membership typesMembership or other role in review committee

Project Management Course with Sergey Nesterov

Gretchen Repasky (Attendee)
May 2015

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

Co-supervisor for PhD thesis project

Gretchen Repasky (Co-supervisor)
2015 → …

Activity: Examination typesSupervisor or co-supervisor of doctoral thesis

Faculty of Medicine, Spring 2015 Research Faculty Meeting

Gretchen Repasky (Speaker: Presenter)
May 2015

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

DSHealth Guidelines for Doctoral Candidates

Gretchen Repasky (Participant)
2015

Activity: Other activity typesTypes for other activities - Other