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Personal profile

Education/Academic qualification

Syöpäbiologia, Dosentti, University of Helsinki

9 Sep 2015 → …

Keywords

  • 3111 Biomedicine
  • 3122 Cancers

International and National Collaboration Publications and projects within past five years.

Publications 2004 2019

  • 55 Article
  • 1 Conference article
  • 1 Doctoral Thesis

Anagrelide for Gastrointestinal Stromal Tumor

Pulkka, O-P., Gebreyohannes, Y. K., Wozniak, A., Mpindi, J-P., Tynninen, O., Icay, K., Cervera, A., Keskitalo, S., Murumägi, A., Kulesskiy, E., Laaksonen, M., Wennerberg, K., Varjosalo, M., Laakkonen, P., Lehtonen, R., Hautaniemi, S., Kallioniemi, O., Schöffski, P., Sihto, H. & Joensuu, H., 1 Mar 2019, In : Clinical Cancer Research. 25, 5, p. 1676-1687 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy

Haikala, H. M., Anttila, J. M., Marques, E., Raatikainen, T., Ilander, M., Hakanen, H., Ala-Hongisto, H., Savelius, M., Balboa, D., Von Eyss, B., Eskelinen, V., Munne, P., Nieminen, A. I., Otonkoski, T., Schüler, J., Laajala, T. D., Aittokallio, T., Sihto, H., Mattson, J., Heikkilä, P. & 7 othersLeidenius, M., Joensuu, H., Mustjoki, S., Kovanen, P., Eilers, M., Leverson, J. D. & Klefström, J., 6 Feb 2019, In : Nature Communications. 10, 17 p., 620.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

SORLA regulates endosomal trafficking and oncogenic fitness of HER2

Pietilä, M., Sahgal, P., Peuhu, E., Jäntti, N. Z., Paatero, I., Närvä, E., Al-Akhrass, H., Lilja, J., Georgiadou, M., Andersen, O. M., Padzik, A., Sihto, H., Joensuu, H., Blomqvist, M., Saarinen, I., Boström, P. J., Taimen, P. & Ivaska, J., 28 May 2019, In : Nature Communications. 10, 16 p., 2340.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Vulnerability of invasive glioblastoma cells to lysosomal membrane destabilization

Le Joncour, V., Filppu, P., Hyvönen, M., Holopainen, M., Turunen, S. P., Sihto, H., Burghardt, I., Joensuu, H., Tynninen, O., Jääskeläinen, J., Weller, M., Lehti, K., Käkelä, R. & Laakkonen, P., Jun 2019, In : EMBO molecular medicine. 11, 6, 21 p., 9034.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Clinical relevance of integrin alpha 4 in gastrointestinal stromal tumours

Pulkka, O-P., Mpindi, J-P., Tynninen, O., Nilsson, B., Kallioniemi, O., Sihto, H. & Joensuu, H., Apr 2018, In : Journal of Cellular and Molecular Medicine. 22, 4, p. 2220-2230 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Projects 2017 2019

Uudet ennustetekijät ja lääkekohteet pahanlaatuisissa liposarkoomissa

Sihto, H., Jaatinen, J. K. & O'Dell, P.

01/01/201731/12/2019

Project: University of Helsinki Three-Year Research Project