Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability

Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC), Lagou, V., Mägi, R., Hottenga, J. J., Fadista, J., Sarin, A-P., Perola, M., Kinnunen, L., Tuomilehto, J., Männistö, S., Kaprio, J., Groop, L. & Tuomi, T., 5 Jan 2021, In : Nature Communications. 12, 1, 18 p., 24.

Research output: Contribution to journal › Article › Scientific › peer-review

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

Surendran, P., Feofanova, E., Lahrouchi, N., Ntalla, I., Karthikeyan, S., Cook, J., Chen, L., Mifsud, B., Yao, C., Kraja, A. T., Cartwright, J. H., Hellwege, J. N., Giri, A., Tragante, V., Thorleifsson, G., Liu, D. J., Prins, B. P., Stewart, I. D., Cabrera, C. P., Eales, J. M. & 261 others, Akbarov, A., Auer, P. L., Bielak, L. F., Bis, J. C., Braithwaite, V. S., Brody, J. A., Daw, E. W., Warren, H. R., Drenos, F., Nielsen, S. F., Faul, J. D., Fauman, E. B., Fava, C., Ferreira, T., Foley, C. N., Franceschini, N., Gao, H., Giannakopoulou, O., Giulianini, F., Gudbjartsson, D. F., Guo, X., Harris, S. E., Havulinna, A. S., Helgadottir, A., Huffman, J. E., Hwang, S-J., Kanoni, S., Kontto, J., Larson, M. G., Li-Gao, R., Lindström, J., Lotta, L. A., Lu, Y., Luan, J., Mahajan, A., Malerba, G., Masca, N. G. D., Mei, H., Menni, C., Mook-Kanamori, D. O., Mosen-Ansorena, D., Muller-Nurasyid, M., Pare, G., Paul, D. S., Perola, M., Poveda, A., Rauramaa, R., Richard, M., Richardson, T. G., Sepulveda, N., Sim, X., Smith, A., Smith, J. A., Staley, J. R., Stanakova, A., Sulem, P., Theriault, S., Thorsteinsdottir, U., Trompet, S., Varga, T. V., Edwards, D. R. V., Veronesi, G., Weiss, S., Willems, S. M., Yao, J., Young, R., Yu, B., Zhang, W., Zhao, J-H., Zhao, W., Zhao, W., Evangelou, E., Aeschbacher, S., Asllanaj, E., Blankenberg, S., Bonnycastle, L. L., Bork-Jensen, J., Brandslund, I., Braund, P. S., Burgess, S., Cho, K., Christensen, C., Connell, J., de Mutsert, R., Dominiczak, A. F., Dorr, M., Eiriksdottir, G., Farmaki, A-E., Gaziano, J. M., Grarup, N., Grove, M. L., Hallmans, G., Hansen, T., Have, C. T., Heiss, G., Jorgensen, M. E., Jousilahti, P., Kajantie, E., Kamat, M., Karajamaki, A., Karpe, F., Koistinen, H. A., Kovesdy, C. P., Kuulasmaa, K., Laatikainen, T., Lannfelt, L., Lee, I-T., Lee, W-J., Linneberg, A., Martin, L. W., Moitry, M., Nadkarni, G., Neville, M. J., Palmer, C. N. A., Papanicolaou, G. J., Pedersen, O., Peters, J., Poulter, N., Rasheed, A., Rasmussen, K. L., Rayner, N. W., Magi, R., Renstrom, F., Rettig, R., Rossouw, J., Schreiner, P. J., Sever, P. S., Sigurdsson, E. L., Skaaby, T., Sun, Y., Sundstrom, J., Thorgeirsson, G., Esko, T., Trabetti, E., Tsao, P. S., Tuomi, T., Turner, S. T., Tzoulaki, I., Vaartjes, I., Vergnaud, A-C., Willer, C. J., Wilson, P. W. F., Witte, D. R., Yonova-Doing, E., Zhang, H., Aliya, N., Almgren, P., Amouyel, P., Asselbergs, F. W., Barnes, M. R., Blakemore, A., Boehnke, M., Bots, M. L., Bottinger, E. P., Buring, J. E., Chambers, J. C., Chen, Y-D. I., Chowdhury, R., Conen, D., Correa, A., Smith, G. D., de Boer, R. A., Deary, I. J., Dedoussis, G., Deloukas, P., Di Angelantonio, E., Elliott, P., Felix, S. B., Ferrieres, J., Ford, I., Fornage, M., Franks, P. W., Franks, S., Frossard, P., Gambaro, G., Gaunt, T. R., Groop, L., Gudnason, V., Harris, T. B., Hayward, C., Hennig, B. J., Herzig, K-H., Ingelsson, E., Tuomilehto, J., Jarvelin, M-R., Jukema, J. W., Kardia, S. L. R., Kee, F., Kooner, J. S., Kooperberg, C., Launer, L. J., Lind, L., Loos, R. J. F., Majumder, A. A. S., Laakso, M., McCarthy, M., Melander, O., Mohlke, K. L., Murray, A. D., Nordestgaard, B. G., Orho-Melander, M., Packard, C. J., Padmanabhan, S., Palmas, W., Polasek, O., Porteous, D. J., Prentice, A. M., Province, M. A., Relton, C. L., Rice, K., Ridker, P. M., Rolandsson, O., Rosendaal, F. R., Rotter, J., Rudan, I., Salomaa, V., Samani, N. J., Sattar, N., Sheu, W. H-H., Smith, B. H., Soranzo, N., Spector, T. D., Starr, J. M., Sebert, S., Taylor, K. D., Lakka, T. A., Timpson, N. J., Tobin, M. D., van der Harst, P., van der Meer, P., Ramachandran, V. S., Verweij, N., Virtamo, J., Volker, U., Weir, D. R., Zeggini, E., Charchar, F. J., Wareham, N. J., Langenberg, C., Tomaszewski, M., Butterworth, A. S., Caulfield, M. J., Danesh, J., Edwards, T. L., Holm, H., Hung, A. M., Lindgren, C. M., Liu, C., Manning, A. K., Morris, A. P., Morrison, A. C., O'Donnell, C. J., Psaty, B. M., Saleheen, D., Stefansson, K., Boerwinkle, E., Chasman, D., Levy, D., Newton-Cheh, C., Munroe, P. B. & Howson, J. M. M., Dec 2020, In : Nature Genetics. 52, 12, 30 p.

Research output: Contribution to journal › Article › Scientific › peer-review

Pitkittynyt ripuli

Arkkila, P., Anttila, V-J., Koistinen, H. & Pikkarainen, S., 2020, In : Duodecim. 136, 5, p. 554-559 6 p.

Research output: Contribution to journal › Article › Professional

Simvastatin profoundly impairs energy metabolism in primary human muscle cells

Mäkinen, S., Datta, N., Nguyen, Y. H., Kyrylenko, P., Laakso, M. & Koistinen, H. A., Nov 2020, In : Endocrine Connections. 9, 11, p. 1103-1113 11 p.

Research output: Contribution to journal › Article › Scientific › peer-review

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

LifeLines Cohort Study, Sung, Y. J., Heikkinen, S. & Koistinen, H. A., 1 Aug 2019, In : Human Molecular Genetics. 28, 15, p. 2615-2633 19 p.

Research output: Contribution to journal › Article › Scientific › peer-review