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Helena Tossavainen

  • Viikinkaari 5, Biocenter 2

    00790 Helsinki

    Finland

20012019
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Publications 2001 2019

2019

Arabidopsis RCD1 coordinates chloroplast and mitochondrial functions through interaction with ANAC transcription factors

Shapiguzov, A., Vainonen, J., Hunter, K. A., Tossavainen, H. P. M., Tiwari, A., Järvi, S., Hellman, M. H., Aarabi, F., Alseekh, S., Wybouw, B., Van Der Kelen, K., Nikkanen, L., Krasensky-Wrzaczek, J., Sipari, N. H., Keinänen, M., Tyystjaervi, E., Rintamäki, E., De Rybel, B., Salojärvi, J. T., Van Breusegem, F. & 6 othersFernie, A. R., Brosche, M. J., Permi, P. E. I., Aro, E-M., Wrzaczek, M. A. & Kangasjärvi, J. S., 15 Feb 2019, In : eLife. 8, 35 p., e43284.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2018

Structural and Functional Insights Into Lysostaphin–Substrate Interaction

Tossavainen, H., Raulinaitis, V., Kauppinen, L., Pentikäinen, U., Maaheimo, H. & Permi, P., 3 Jul 2018, In : Frontiers in Molecular Biosciences. 5, 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2017

H-1, C-13 and N-15 NMR chemical shift assignments of A-thaliana RCD1 RST

Tossavainen, H., Hellman, M., Vainonen, J. P., Kangasjarvi, J. & Permi, P., Oct 2017, In : Biomolecular NMR assignments. 11, 2, p. 207-210 4 p.

Research output: Contribution to journalArticleScientificpeer-review

H-1, C-13 and N-15 resonance assignments of the new lysostaphin family endopeptidase catalytic domain from Staphylococcus aureus

Raulinaitis, V., Tossavainen, H., Aitio, O., Seppala, R. & Permi, P., Apr 2017, In : Biomolecular NMR assignments. 11, 1, p. 69-73 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Identification and structural characterization of LytU, a unique peptidoglycan endopeptidase from the lysostaphin family

Raulinaitis, V., Tossavainen, H., Aitio, O., Juuti, J. T., Hiramatsu, K., Kontinen, V. & Permi, P., 20 Jul 2017, In : Scientific Reports. 7, 14 p., 6020.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2016

Redox-dependent disulfide bond formation in SAP30L corepressor protein: Implications for structure and function

Laitaoja, M., Tossavainen, H., Pihlajamaa, T., Valjakka, J., Viiri, K., Lohi, O., Permi, P. & Jänis, J., Mar 2016, In : Protein Science. 25, 3, p. 572-586 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Structural Basis of the High Affinity Interaction between the Alphavirus Nonstructural Protein-3 (nsP3) and the SH3 Domain of Amphiphysin-2

Tossavainen, H., Aitio, O., Hellman, M., Saksela, K. & Permi, P., 29 Jul 2016, In : Journal of Biological Chemistry. 291, 31, p. 16307-16317 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
2015

Flexible Structure of Peptide-Bound Filamin A Mechanosensor Domain Pair 20-21

Seppälä, J., Tossavainen, H., Rodic, N., Permi, P., Pentikäinen, U. & Ylänne, J., 31 Aug 2015, In : PLoS One. 10, 8, 19 p., 0136969.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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H-N, N, C-alpha, C-beta and C' assignments of the intrinsically disordered C-terminus of human adenosine A(2A) receptor

Tossavainen, H., Hellman, M., Piirainen, H., Jaakola, V-P. & Permi, P., Oct 2015, In : Biomolecular NMR assignments. 9, 2, p. 403-406 4 p.

Research output: Contribution to journalArticleScientificpeer-review

H-N, N-H, C-alpha, C-beta, and methyl group assignments of filamin multidomain fragments IgFLNc4-5 and IgFLNa3-5

Tossavainen, H., Seppälä, J., Sethi, R., Pihlajamaa, T. & Permi, P., Apr 2015, In : Biomolecular NMR assignments. 9, 1, p. 47-50 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Human Adenosine A2A Receptor Binds Calmodulin with High Affinity in a Calcium-Dependent Manner

Piirainen, H., Hellman, M., Tossavainen, H., Permi, P., Kursula, P. & Jaakola, V-P., 17 Feb 2015, In : Biophysical Journal. 108, 4, p. 903-917 15 p.

Research output: Contribution to journalArticleScientificpeer-review

2014

A Novel Structural Unit in the N-terminal Region of Filamins

Sethi, R., Seppala, J., Tossavainen, H., Ylilauri, M., Ruskamo, S., Pentikainen, O. T., Pentikainen, U., Permi, P. & Ylanne, J., 21 Mar 2014, In : Journal of Biological Chemistry. 289, 12, p. 8588-8598 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Chimeric Avidin - NMR Structure and Dynamics of a 56 kDa Homotetrameric Thermostable Protein

Tossavainen, H., Kukkurainen, S., Määttä, J. A. E., Kähkönen, N., Pihlajamaa, T., Hytönen, V. P., Kulomaa, M. S. & Permi, P., 24 Jun 2014, In : PLoS One. 9, 6, 12 p., 100564.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2013

Resonance assignments of the 56 kDa chimeric avidin in the biotin-bound and free forms

Tossavainen, H., Helppolainen, S. H., Määttä, J. A. E., Pihlajamaa, T., Hytönen, V. P., Kulomaa, M. S. & Permi, P., 2013, In : Biomolecular NMR assignments. 7, 1, p. 35-38 4 p.

Research output: Contribution to journalArticleScientificpeer-review

2012

Model of a Six Immunoglobulin-Like Domain Fragment of Filamin A (16-21) Built Using Residual Dipolar Couplings

Tossavainen, H., Koskela, O., Jiang, P., Ylänne, J., Campbell, I. D., Kilpeläinen, I. & Permi, P., 2012, In : Journal of the American Chemical Society. 134, 15, p. 6660-6672 13 p.

Research output: Contribution to journalArticleScientificpeer-review

2011

Characterization of Intrinsically Disordered Prostate Associated Gene (PAGE5) at Single Residue Resolution by NMR Spectroscopy

Hellman, M., Tossavainen, H., Rappu, P., Heino, J. & Permi, P., 2011, In : PLoS One. 6, 11, p. e26633 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2009

An intraresidual i(HCA)CO(CA)NH experiment for the assignment of main-chain resonances in ¹N, ¹³C labeled proteins

Mäntylahti, S., Tossavainen, H., Hellman, M. & Permi, P., 2009, In : Biomolecular NMR assignments. 45, 3, p. 301-310 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Solution structure of the parvulin-type PPlase domain of staphylococcus aureus PrsA-implications for the catalytic mechanism of parvulins

Heikkinen, O., Seppala, R., Tossavainen, H., Heikkinen, S., Koskela, H., Permi, P. & Kilpeläinen, I., 2009, In : BMC Structural Biology. 9, p. art. 17 13 p.

Research output: Contribution to journalArticleScientificpeer-review

2008

Structural basis of PxxDY motif recognition in SH3 binding

Aitio, O., Hellman, M., Kesti, T., Kleino, I., Samuilova, O., Pääkkönen, K., Tossavainen, H., Saksela, K. & Permi, P., 2008, In : Journal of Molecular Biology. 382, 1, p. 167-178 12 p.

Research output: Contribution to journalArticleScientificpeer-review

The solution structure of the amino-terminal domain of human DNA polymerase subunit B is homologous to C-domains of AAA+ proteins

Nuutinen, T., Tossavainen, H., Fredriksson, K., Pirilä, P., Permi, P., Pospiech, H. & Syväoja, J. E., 2008, In : Nucleic Acids Research. 36, 15, p. 5102-5110 9 p.

Research output: Contribution to journalArticleScientificpeer-review

2007

Crystal structure of the N-terminal NC4 domain of collagen IX, a zinc binding member of the laminin-neurexin-sex hormone binding globulin (LNS) domain family

Leppänen, V-M., Tossavainen, H., Permi, P., Lehtiö, L., Rönnholm, G., Goldman, A., Kilpeläinen, I. & Pihlajamaa, T., 2007, In : Journal of Biological Chemistry. 282, 32, p. 23219-23230 12 p.

Research output: Contribution to journalArticleScientificpeer-review

2006

NMR solution structure and characterization of substrate binding site of the PPIase domain of PrsA protein from Bacillus subtilis

Tossavainen, H., Permi, P., Purhonen, S. L., Sarvas, M., Kilpeläinen, I. & Seppälä, R., 2006, In : FEBS Letters. 580, p. 1822-1826 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Peptide binding and NMR analysis of the interaction between SAP97 PDZ2 and GluR-A: potential involvement of a disulfide bond

von Ossowski, L., Tossavainen, H., von Ossowski, I., Cai, C., Aitio, O., Fredriksson, K., Permi, P., Annila, A. & Keinänen, K., 2006, In : Biochemistry. 45, 17, p. 5567-5575 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Simultaneous determination of one- and two-bond scalar and residual dipolar couplings between ¹³C', ¹³C[sup ] and ¹N spins proteins

Puttonen, E., Tossavainen, H. & Permi, P., 2006, In : Magnetic Resonance in Chemistry. 44, p. S168-S176 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Solution structures of the first and fourth TSR domains of F-spondin

Pääkkönen, K., Tossavainen, H., Permi, P., Rakkolainen, H., Rauvala, H., Raulo, E., Kilpeläinen, I. & Guntert, P., 2006, In : Proteins : structure, function, and genetics. 64, 3, p. 665-672 8 p.

Research output: Contribution to journalArticleScientificpeer-review

The layered fold of the TSR domain of P. falciparum TRAP contains a heparin binding site

Tossavainen, H., Pihlajamaa, T., Huttunen, T. K., Raulo, E., Rauvala, H., Permi, P. & Kilpeläinen, I., 2006, In : Protein Science. 15, 7, p. 1760-1768 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Towards unambiguous assignment of methyl-containing residues by double and triple sensitivity-enhanced HCCmHm-TOCSY experiments

Wurtz, P., Hellman, M., Tossavainen, H. & Permi, P., 2006, In : Journal of Biomolecular NMR. 36, p. 13-26 14 p.

Research output: Contribution to journalArticleScientificpeer-review

2004

Efficient assignment of methyl resonances: enhanced sensitivity by gradient selection in a DE-MQ–(H)CCmHm–TOCSY experiment

Permi, P., Tossavainen, H. & Hellman, M., 2004, In : Journal of Biomolecular NMR. 30, p. 275-282 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Optimized Pathway Selection in Intraresidual Triple-Resonance Experiments

Permi, P. & Tossavainen, H., 2004, In : Journal of Magnetic Resonance. 170, p. 244-251

Research output: Contribution to journalArticleScientificpeer-review

2001

Characterization of apo and partially saturated states of calerythrin, an EF-hand protein from S-erythraea: A molten globule when deprived of Ca2+

Aitio, H., Laakso, T., Pihlajamaa, T., Torkkeli, M., Kilpelainen, I., Drakenberg, T., Serimaa, R. & Annila, A., 2001, In : Protein Science. 10, 1, p. 74-82 9 p.

Research output: Contribution to journalArticleScientificpeer-review