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  • 2022

    Common variants in breast cancer risk loci predispose to distinct tumor subtypes

    NBCS Collaborators, ABCTB Investigators , kConFab-AOCS Investigators, Ahearn, T. U., Zhang, H., Michailidou, K., Blomqvist, C. & Nevanlinna, H., 4 Jan 2022, In: Breast Cancer Research. 24, 1, 13 p., 2.

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  • 2021

    A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

    GEMO Study Collaborators, EMBRACE Collaborators, kConFab Investigators, HEBON Investigators, ABCTB Investigators , Coignard, J., Lush, M., Beesley, J., Blomqvist, C., Kiiski, J. I. & Nevanlinna, H., 17 Feb 2021, In: Nature Communications. 12, 1, 22 p., 1078.

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  • Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment

    NBCS Collaborators, ABCTB Investigators , kConFab Investigators, Morra, A., Escala-Garcia, M., Beesley, J., Muranen, T. A. & Nevanlinna, H., 18 Aug 2021, In: Breast Cancer Research. 23, 1, 18 p., 86.

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  • Common susceptibility loci for male breast cancer

    Maguire, S., Perraki, E., Tomczyk, K., KConFab Consortium, Trainer, A., James, P., Bojesen, S., Flyger, H., Nevanlinna, H., Mattson, J., Friedman, E., Laitman, Y., Palli, D., Masala, G., Zanna, I., Ottini, L., Silvestri, V., Hollestelle, A., Hooning, M. J., Novakovic, S. & 18 others, Krajc, M., Gago-Dominguez, M., Castelao, J. E., Olsson, H., Hedenfalk, I., Saloustros, E., Georgoulias, V., Easton, D. F., Pharoah, P., Dunning, A. M., Bishop, D. T., Neuhausen, S. L., Steele, L., Ashworth, A., Garcia Closas, M., Houlston, R., Swerdlow, A. & Orr, N., Apr 2021, In: Journal of the National Cancer Institute. Monographs. 113, 4, p. 453-461 9 p., 101.

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  • Cross-Cancer Genome-Wide Association Study of Endometrial Cancer and Epithelial Ovarian Cancer Identifies Genetic Risk Regions Associated with Risk of Both Cancers

    OPAL Study Grp, AOCS Grp, Glubb, D. M., Thompson, D. J., Aben, K. K. H., Butzow, R. & Nevanlinna, H., Jan 2021, In: Cancer Epidemiology, Biomarkers & Prevention. 30, 1, p. 217-228 12 p.

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  • CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers

    NBCS Collaborators, AOCS Grp, ABCTB Investigators , kConFab Investigators, Johnson, N., Maguire, S., Morra, A., Blomqvist, C. & Nevanlinna, H., 16 Feb 2021, In: British Journal of Cancer. 124, 4, p. 842-854 13 p.

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  • Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer: Can Gene-Environment Interactions Be Detected Only among Candidate SNPs from Genome-Wide Association Studies?

    kConFab Investigators, NBCS Collaborators, Park, J., Choi, J-Y., Choi, J., Blomqvist, C. & Nevanlinna, H., May 2021, In: Cancers. 13, 10, 21 p., 2370.

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  • Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis

    kConFab-AOCS Investigators, Escala-Garcia, M., Canisius, S., Keeman, R., Muranen, T. A. & Nevanlinna, H., 5 Oct 2021, In: Scientific Reports. 11, 1, 11 p., 19787.

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  • High mir-30 expression associates with improved breast cancer patient survival and treatment outcome

    Jamshidi, M., Fagerholm, R., Muranen, T. A., Kaur, S., Potdar, S., Khan, S., Netti, E., Mpindi, J-P., Yadav, B., Kiiski, J. I., Aittomäki, K., Heikkilä, P., Saarela, J., Bützow, R., Blomqvist, C. & Nevanlinna, H., Jun 2021, In: Cancers. 13, 12, 15 p., 2907.

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  • Mendelian randomisation study of smoking exposure in relation to breast cancer risk

    NBCS Collaborators, ABCTB Investigators , kConFab Investigators, Park, H. A., Neumeyer, S., Michailidou, K., Muranen, T. A. & Nevanlinna, H., 2 Aug 2021, (E-pub ahead of print) In: British Journal of Cancer. 11 p.

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  • The predictive ability of the 313 variant-based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant

    GEMO Study Collaborators, EMBRACE Collaborators, OCGN Investigators, HEBON Investigators, kConFab Investigators, Lakeman, I. M. M., van den Broek, A. J., Vos, J. A. M. & Nevanlinna, H., Sep 2021, In: Genetics In medicine. 23, 9, p. 1726-1737 12 p.

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  • 2020

    A Mendelian randomization analysis of circulating lipid traits and breast cancer risk

    Breast Canc Assoc Consortium, Beeghly-Fadiel, A., Khankari, N. K., Delahanty, R. J., Zheng, W., Blomqvist, C. & Nevanlinna, H., Aug 2020, In: International Journal of Epidemiology. 49, 4, p. 1117-1131 15 p.

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  • A network analysis to identify mediators of germline-driven differences in breast cancer prognosis

    Escala-Garcia, M., Abraham, J., Andrulis, I. L., Anton-Culver, H., Arndt, V., Ashworth, A., Auer, P. L., Auvinen, P., Beckmann, M. W., Beesley, J., Behrens, S., Benitez, J., Bermisheva, M., Blomqvist, C., Blot, W., Bogdanova, N. V., Bojesen, S. E., Bolla, M. K., Børresen-Dale, A-L., Brauch, H. & 125 others, Brenner, H., Brucker, S. Y., Burwinkel, B., Caldas, C., Canzian, F., Chang-Claude, J., Chanock, S. J., Chin, S-F., Clarke, C. L., Couch, F. J., Cox, A., Cross, S. S., Czene, K., Daly, M. B., Dennis, J., Devilee, P., Dunn, J. A., Dunning, A. M., Dwek, M., Earl, H. M., Eccles, D. M., Eliassen, A. H., Ellberg, C., Evans, D. G., Fasching, P. A., Figueroa, J., Flyger, H., Gago-Dominguez, M., Gapstur, S. M., García-Closas, M., García-Sáenz, J. A., Gaudet, M. M., George, A., Giles, G. G., Goldgar, D. E., González-Neira, A., Grip, M., Guénel, P., Guo, Q., Haiman, C. A., Håkansson, N., Hamann, U., Harrington, P. A., Hiller, L., Hooning, M. J., Hopper, J. L., Howell, A., Huang, C-S., Huang, G., Hunter, D. J., Jakubowska, A., John, E. M., Kaaks, R., Kapoor, P. M., Keeman, R., Kitahara, C. M., Koppert, L. B., Kraft, P., Kristensen, V. N., Lambrechts, D., Le Marchand, L., Lejbkowicz, F., Lindblom, A., Lubiński, J., Mannermaa, A., Manoochehri, M., Manoukian, S., Margolin, S., Martinez, M. E., Maurer, T., Mavroudis, D., Meindl, A., Milne, R. L., Mulligan, A. M., Neuhausen, S. L., Nevanlinna, H., Newman, W. G., Olshan, A. F., Olson, J. E., Olsson, H., Orr, N., Peterlongo, P., Petridis, C., Prentice, R. L., Presneau, N., Punie, K., Ramachandran, D., Rennert, G., Romero, A., Sachchithananthan, M., Saloustros, E., Sawyer, E. J., Schmutzler, R. K., Schwentner, L., Scott, C., Simard, J., Sohn, C., Southey, M. C., Swerdlow, A. J., Tamimi, R. M., Tapper, W. J., Teixeira, M. R., Terry, M. B., Thorne, H., Tollenaar, R. A. E. M., Tomlinson, I., Troester, M. A., Truong, T., Turnbull, C., Vachon, C. M., van der Kolk, L. E., Wang, Q., Winqvist, R., Wolk, A., Yang, X. R., Ziogas, A., Pharoah, P. D. P., Hall, P., Wessels, L. F. A., Chenevix-Trench, G., Bader, G. D., Dörk, T., Easton, D. F., Canisius, S. & Schmidt, M. K., 16 Jan 2020, In: Nature Communications. 11, 1, 14 p., 312.

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  • Association of genomic domains in BRCA1 and BRCA2 with prostate cancer risk and aggressiveness

    Patel, V. L., Busch, E. L., Friebel, T. M., Cronin, A., Leslie, G., McGuffog, L., Adlard, J., Agata, S., Agnarsson, B. A., Ahmed, M., Aittomäki, K., Alducci, E., Andrulis, I. L., Arason, A., Arnold, N., Artioli, G., Arver, B., Auber, B., Azzollini, J., Balmaña, J. & 239 others, Barkardottir, R. B., Barnes, D. R., Barroso, A., Barrowdale, D., Belotti, M., Benitez, J., Bertelsen, B., Blok, M. J., Bodrogi, I., Bonadona, V., Bonanni, B., Bondavalli, D., Boonen, S. E., Borde, J., Borg, A., Bradbury, A. R., Brady, A., Brewer, C., Brunet, J., Buecher, B., Buys, S. S., Cabezas-Camarero, S., Caldes, T., Caliebe, A., Caligo, M. A., Calvello, M., Campbell, I. G., Carnevali, I., Carrasco, E., Chan, T. L., Chu, A. T. W., Chung, W. K., Claes, K. B. M., Cook, J., Cortesi, L., Couch, F. J., Daly, M. B., Damante, G., Darder, E., Davidson, R., De La Hoya, M., Della Puppa, L., Dennis, J., Díez, O., Ding, Y. C., Ditsch, N., Domchek, S. M., Donaldson, A., Dworniczak, B., Easton, D. F., Eccles, D. M., Eeles, R. A., Ehrencrona, H., Ejlertsen, B., Engel, C., Evans, D. G., Faivre, L., Faust, U., Feliubadalo, L., Foretova, L., Fostira, F., Fountzilas, G., Frost, D., García-Barberan, V., Garre, P., Gauthier-Villars, M., Geczi, L., Gehrig, A., Gerdes, A-M., Gesta, P., Giannini, G., Glendon, G., Godwin, A. K., Goldgar, D. E., Greene, M. H., Gutierrez-Barrera, A. M., Hahnen, E., Hamann, U., Hauke, J., Herold, N., Hogervorst, F. B. L., Honisch, E., Hopper, J. L., Hulick, P. J., Izatt, L., Jager, A., James, P., Janavicius, R., Jensen, U. B., Jensen, T. D., Johannsson, O. T., John, E. M., Joseph, V., Kang, E., Kast, K., Kiiski, J. I., Kim, S-W., Kim, Z., Ko, K-P., Konstantopoulou, I., Kramer, G., Krogh, L., Kruse, T. A., Kwong, A., Larsen, M., Lasset, C., Lautrup, C., Lazaro, C., Lee, J., Lee, J. W., Lee, M. H., Lemke, J., Lesueur, F., Liljegren, A., Lindblom, A., Llovet, P., Lopez-Fernandez, A., Lopez-Perolio, I., Lorca, V., Loud, J. T., Ma, E. S. K., Mai, P. L., Manoukian, S., Mari, V., Martin, L., Matricardi, L., Mebirouk, N., Medici, V., Meijers-Heijboer, H. E. J., Meindl, A., Mensenkamp, A. R., Miller, C., Gomes, D. M., Montagna, M., Mooij, T. M., Moserle, L., Mouret-Fourme, E., Mulligan, A. M., Nathanson, K. L., Navratilova, M., Nevanlinna, H., Niederacher, D., Cilius Nielsen, F. C., Nikitina-Zake, L., Offit, K., Olah, E., Olopade, O. I., Ong, K-R., Osorio, A., Ott, C-E., Palli, D., Park, S. K., Parsons, M. T., Pedersen, I. S., Peissel, B., Peixoto, A., Perez-Segura, P., Peterlongo, P., Petersen, A. H., Porteous, M. E., Pujana, M. A., Radice, P., Ramser, J., Rantala, J., Rashid, M. U., Rhiem, K., Rizzolo, P., Robson, M. E., Rookus, M. A., Rossing, C. M., Ruddy, K. J., Santos, C., Saule, C., Scarpitta, R., Schmutzler, R. K., Schuster, H., Senter, L., Seynaeve, C. M., Shah, P. D., Sharma, P., Shin, V. Y., Silvestri, V., Simard, J., Singer, C. F., Skytte, A-B., Snape, K., Solano, A. R., Soucy, P., Southey, M. C., Spurdle, A. B., Steele, L., Steinemann, D., Stoppa-Lyonnet, D., Stradella, A., Sunde, L., Sutter, C., Tan, Y. Y., Teixeira, M. R., Teo, S. H., Thomassen, M., Tibiletti, M. G., Tischkowitz, M., Tognazzo, S., Toland, A. E., Tommasi, S., Torres, D., Toss, A., Trainer, A. H., Tung, N., Van Asperen, C. J., Van Der Baan, F. H., Van Der Kolk, L. E., Van Der Luijt, R. B., Van Hest, L. P., Varesco, L., Varon-Mateeva, R., Viel, A., Vierstrate, J., Villa, R., Von Wachenfeldt, A., Wagner, P., Wang-Gohrke, S., Wappenschmidt, B., Weitzel, J. N., Wieme, G., Yadav, S., Yannoukakos, D., Yoon, S-Y., Zanzottera, C., Zorn, K. K., D’Amico, A. V., Freedman, M. L., Pomerantz, M. M., Chenevix-Trench, G., Antoniou, A. C., Neuhausen, S. L., Ottini, L., Nielsen, H. R. & Rebbeck, T. R., 1 Feb 2020, In: Cancer Research. 80, 3, p. 624-638 15 p.

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  • Association of germline variation with the survival of women with BRCA1/2 pathogenic variants and breast cancer

    kConFab Investigators, HEBON Investigators, SWE BRCA Investigators, Muranen, T. A., Khan, S., Fagerholm, R., Aittomäki, K., Cunningham, J. M., Blomqvist, C. & Nevanlinna, H., 10 Sep 2020, In: Npj breast cancer. 6, 1, 13 p., 44.

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  • Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk

    NBCS Collaborators, ABCTB Investigators , kConFab Investigators, Kramer, I., Hooning, M. J., Mavaddat, N., Muranen, T. A. & Nevanlinna, H., 5 Nov 2020, In: American Journal of Human Genetics. 107, 5, p. 837-848 12 p.

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  • Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families

    Yang, X., Leslie, G., Doroszuk, A., Aittomäki, K., Blomqvist, C., Heikkinen, T., Nevanlinna, H. & Tischkowitz, M., 1 Mar 2020, In: Journal of Clinical Oncology. 38, 7, p. 674-+ 14 p.

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  • Characterization of the Cancer Spectrum in Men With Germline BRCA1 and BRCA2 Pathogenic Variants Results From the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

    CIMBA Grp, Silvestri, V., Leslie, G., Barnes, D. R., Aittomäki, K. & Nevanlinna, H., Aug 2020, In: JAMA Oncology. 6, 8, p. 1218-1230 13 p.

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  • Constitutional mosaicism for aBRCA2mutation as a cause of early-onset breast cancer

    Alhopuro, P., Vainionpää, R., Anttonen, A-K., Aittomäki, K., Nevanlinna, H. & Pöyhönen, M., Oct 2020, In: Familial Cancer. 19, 4, p. 307-310 4 p.

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  • Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

    Fachal, L., Aschard, H., Beesley, J., Barnes, D. R., Allen, J., Kar, S., Pooley, K. A., Dennis, J., Michailidou, K., Turman, C., Soucy, P., Lemaçon, A., Lush, M., Tyrer, J. P., Ghoussaini, M., Marjaneh, M. M., Jiang, X., Agata, S., Aittomäki, K., Alonso, M. R. & 556 others, Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., Arason, A., Arndt, V., Aronson, K. J., Arun, B. K., Auber, B., Auer, P. L., Azzollini, J., Balmaña, J., Barkardottir, R. B., Barrowdale, D., Beeghly-Fadiel, A., Benitez, J., Bermisheva, M., Białkowska, K., Blanco, A. M., Blomqvist, C., Blot, W., Bogdanova, N. V., Bojesen, S. E., Bolla, M. K., Bonanni, B., Borg, A., Bosse, K., Brauch, H., Brenner, H., Briceno, I., Brock, I. W., Brooks-Wilson, A., Brüning, T., Burwinkel, B., Buys, S. S., Cai, Q., Caldés, T., Caligo, M. A., Camp, N. J., Campbell, I., Canzian, F., Carroll, J. S., Carter, B. D., Castelao, J. E., Chiquette, J., Christiansen, H., Chung, W. K., Claes, K. B. M., Clarke, C. L., Mari, V., Berthet, P., Castera, L., Vaur, D., Lallaoui, H., Bignon, Y-J., Uhrhammer, N., Bonadona, V., Lasset, C., Révillion, F., Vennin, P., Muller, D., Gomes, D. M., Ingster, O., Coupier, I., Pujol, P., Collonge-Rame, M-A., Mortemousque, I., Bera, O., Rose, M., Baurand, A., Bertolone, G., Faivre, L., Dreyfus, H., Leroux, D., Venat-Bouvet, L., Bézieau, S., Delnatte, C., Chiesa, J., Gilbert-Dussardier, B., Gesta, P., Prieur, F. P., Bronner, M., Sokolowska, J., Coulet, F., Boutry-Kryza, N., Calender, A., Giraud, S., Leone, M., Fert-Ferrer, S., Stoppa-Lyonnet, D., Jiao, Y., Lesueur, F. L., Mebirouk, N., Barouk-Simonet, E., Bubien, V., Longy, M., Sevenet, N., Gladieff, L., Toulas, C., Reimineras, A., Sobol, H., Paillerets, BB-D., Cabaret, O., Caron, O., Guillaud-Bataille, M., Rouleau, E., Belotti, M., Buecher, B., Caputo, S., Colas, C., Pauw, A. D., Fourme, E., Gauthier-Villars, M., Golmard, L., Moncoutier, V., Saule, C., Donaldson, A., Murray, A., Brady, A., Brewer, C., Pottinger, C., Miller, C., Gallagher, D., Gregory, H., Cook, J., Eason, J., Adlard, J., Barwell, J., Ong, K-R., Snape, K., Walker, L., Izatt, L., Side, L., Tischkowitz, M., Rogers, M. T., Porteous, M. E., Ahmed, M., Morrison, P. J., Brennan, P., Eeles, R., Davidson, R., Collée, M., Cornelissen, S., Couch, F. J., Cox, A., Cross, S. S., Cybulski, C., Czene, K., Daly, M. B., de la Hoya, M., Devilee, P., Diez, O., Ding, Y. C., Dite, G. S., Domchek, S. M., Dörk, T., dos-Santos-Silva, I., Droit, A., Dubois, S., Dumont, M., Duran, M., Durcan, L., Dwek, M., Eccles, D. M., Engel, C., Eriksson, M., Evans, D. G., Fasching, P. A., Fletcher, O., Floris, G., Flyger, H., Foretova, L., Foulkes, W. D., Friedman, E., Fritschi, L., Frost, D., Gabrielson, M., Gago-Dominguez, M., Gambino, G., Ganz, P. A., Gapstur, S. M., Garber, J., García-Sáenz, J. A., Gaudet, M. M., Georgoulias, V., Giles, G., Glendon, G., Godwin, A. K., Goldberg, M. S., Goldgar, D. E., González-Neira, A., Tibiletti, M. G., Greene, M. H., Grip, M., Gronwald, J., Grundy, A., Guénel, P., Hahnen, E., Haiman, C. A., Håkansson, N., Hall, P., Hamann, U., Harrington, P. A., Hartikainen, J. M., Hartman, M., He, W., Healey, C. S., Heemskerk-Gerritsen, B. A. M., Heyworth, J., Hillemanns, P., Hogervorst, F. B. L., Hollestelle, A., Hooning, M., Hopper, J., Howell, A., Huang, G., Hulick, P. J., Imyanitov, E. N., Sexton, A., Christian, A., Trainer, A., Spigelman, A., Fellows, A., Shelling, A., Fazio, A. D., Blackburn, A., Crook, A., Meiser, B., Patterson, B., Clarke, C., Saunders, C., Hunt, C., Scott, C., Amor, D., Marsh, D., Edkins, E., Salisbury, E., Haan, E., Neidermayr, E., Macrea, F., Farshid, G., Lindeman, G., Chenevix-Trench, G., Mann, G., Giles, G., Gill, G., Thorne, H., Campbell, I., Hickie, I., Winship, I., Flanagan, J., Kollias, J., Visvader, J., Stone, J., Taylor, J., Burke, J., Saunus, J., Forbes, J., Hopper, J., Beesley, J., Kirk, J., French, J., Tucker, K., Wu, K., Phillips, K., Lipton, L., Andrews, L., Lobb, L., Walker, L., Kentwell, M., Spurdle, M., Cummings, M., Gleeson, M., Harris, M., Jenkins, M., Young, M. A., Delatycki, M., Wallis, M., Burgess, M., Price, M., Brown, M., Southey, M., Bogwitz, M., Field, M., Friedlander, M., Gattas, M., Saleh, M., Hayward, N., Pachter, N., Cohen, P., Duijf, P., James, P., Simpson, P., Fong, P., Butow, P., Williams, R., Kefford, R., Scott, R., Milne, R. L., Balleine, R., Dawson, S. J., Lok, S., O’Connell, S., Greening, S., Nightingale, S., Edwards, S., Fox, S., McLachlan, S-A., Lakhani, S., Antill, Y., Aalfs, C., Meijers-Heijboer, H., van Engelen, K., Gille, H., Boere, I., Collée, M., van Deurzen, C., Hooning, M., Obdeijn, I-M., van den Ouweland, A., Seynaeve, C., Siesling, S., Verloop, J., van Asperen, C. J., Devilee, P., van Cronenburg, T., Blok, R., de Boer, M., Garcia, E. G., Adank, M., Hogervorst, F., Jenner, D., van Leeuwen, F., Rookus, M., Russell, N., Schmidt, M., van den Belt-Dusebout, S., Kets, C., Mensenkamp, A., de Bock, T., van der Hout, A., Mourits, M., Oosterwijk, J., Ausems, M., Koudijs, M., Clarke, C., Marsh, D., Scott, R., Baxter, R., Yip, D., Carpenter, J., Davis, A., Pathmanathan, N., Simpson, P., Graham, D., Sachchithananthan, M., Isaacs, C., Iwasaki, M., Jager, A., Jakimovska, M., Jakubowska, A., James, P. A., Janavicius, R., Jankowitz, R. C., John, E. M., Johnson, N., Jones, M. E., Jukkola-Vuorinen, A., Jung, A., Kaaks, R., Kang, D., Kapoor, P. M., Karlan, B. Y., Keeman, R., Kerin, M. J., Khusnutdinova, E., Kiiski, J. I., Kirk, J., Kitahara, C. M., Ko, Y-D., Konstantopoulou, I., Kosma, V-M., Koutros, S., Kubelka-Sabit, K., Kwong, A., Kyriacou, K., Laitman, Y., Lambrechts, D., Lee, E., Leslie, G., Lester, J., Lesueur, F., Lindblom, A., Lo, W-Y., Long, J., Lophatananon, A., Loud, J. T., Lubiński, J., MacInnis, R. J., Maishman, T., Makalic, E., Mannermaa, A., Manoochehri, M., Manoukian, S., Margolin, S., Martinez, M. E., Matsuo, K., Maurer, T., Mavroudis, D., Mayes, R., McGuffog, L., McLean, C., Mebirouk, N., Meindl, A., Miller, A., Miller, N., Montagna, M., Moreno, F., Muir, K., Mulligan, A. M., Muñoz-Garzon, V. M., Muranen, T. A., Narod, S. A., Nassir, R., Nathanson, K. L., Neuhausen, S. L., Nevanlinna, H., Neven, P., Nielsen, F. C., Nikitina-Zake, L., Norman, A., Offit, K., Olah, E., Olopade, O. I., Olsson, H., Orr, N., Osorio, A., Pankratz, V. S., Papp, J., Park, S. K., Park-Simon, T-W., Parsons, M. T., Paul, J., Pedersen, I. S., Peissel, B., Peshkin, B., Peterlongo, P., Peto, J., Plaseska-Karanfilska, D., Prajzendanc, K., Prentice, R., Presneau, N., Prokofyeva, D., Pujana, M. A., Pylkäs, K., Radice, P., Ramus, S. J., Rantala, J., Rau-Murthy, R., Rennert, G., Risch, H. A., Robson, M., Romero, A., Rossing, M., Saloustros, E., Sánchez-Herrero, E., Sandler, D. P., Santamariña, M., Saunders, C., Sawyer, E. J., Scheuner, M. T., Schmidt, D. F., Schmutzler, R. K., Schneeweiss, A., Schoemaker, M. J., Schöttker, B., Schürmann, P., Scott, C., Scott, R. J., Senter, L., Seynaeve, C. M., Shah, M., Sharma, P., Shen, C-Y., Shu, X-O., Singer, C. F., Slavin, T. P., Smichkoska, S., Southey, M. C., Spinelli, J. J., Spurdle, A. B., Stone, J., Stoppa-Lyonnet, D., Sutter, C., Swerdlow, A. J., Tamimi, R. M., Tan, Y. Y., Tapper, W. J., Taylor, J. A., Teixeira, M. R., Tengström, M., Teo, S. H., Terry, M. B., Teulé, A., Thomassen, M., Thull, D. L., Tischkowitz, M., Toland, A. E., Tollenaar, R. A. E. M., Tomlinson, I., Torres, D., Torres-Mejía, G., Troester, M. A., Truong, T., Tung, N., Tzardi, M., Ulmer, H-U., Vachon, C. M., van Asperen, C. J., van der Kolk, L. E., van Rensburg, E. J., Vega, A., Viel, A., Vijai, J., Vogel, M. J., Wang, Q., Wappenschmidt, B., Weinberg, C. R., Weitzel, J. N., Wendt, C., Wildiers, H., Winqvist, R., Wolk, A., Wu, A. H., Yannoukakos, D., Zhang, Y., Zheng, W., Hunter, D., Pharoah, P. D. P., Chang-Claude, J., García-Closas, M., Schmidt, M. K., Milne, R. L., Kristensen, V. N., French, J. D., Edwards, S. L., Antoniou, A. C., Chenevix-Trench, G., Simard, J., Easton, D. F., Kraft, P., Dunning, A. M., Collaborators, GEMO. S., Collaborators, EMBRACE., Investigators, KC., Investigators, HEBON. & Investigators, ABCTB., Jan 2020, In: Nature Genetics. 52, 1, p. 56-73 25 p.

    Research output: Contribution to journalArticlepeer-review

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  • Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

    kConFab Investigators, ABCTB Investigators , EMBRACE Study, GEMO Study Collaborators, Zhan, H., Ahearn, T. U., Lecarpentier, J., Aittomäki, K., Blomqvist, C., Khan, S., Muranen, T. A. & Nevanlinna, H., Jun 2020, In: Nature Genetics. 52, 6, p. 572-+ 19 p.

    Research output: Contribution to journalArticlepeer-review

  • Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk

    NBCS Collaborators, ABCTB Investigators , Liu, J., van der Smissen, W. J. C. P., Collee, J. M., Aittomäki, K. & Nevanlinna, H., 16 Jun 2020, In: Scientific Reports. 10, 1, 14 p., 9688.

    Research output: Contribution to journalArticlepeer-review

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  • Ovarian and Breast Cancer Risks Associated With Pathogenic Variants in RAD51C and RAD51D

    kConFab Investigators, Yang, X., Nevanlinna, H., Aittomäki, K. & Pelttari, L. M., Dec 2020, In: Journal of the National Cancer Institute. 112, 12, p. 1242-1250 9 p., 030.

    Research output: Contribution to journalArticlepeer-review

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  • Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants

    GEMO Study Collaborators, EMBRACE Collaborators, kConFab Investigators, HEBON Investigators, GENEPSO Investigators, Consortium Investigators Modifiers, Barnes, D. R., Rookus, M. A., McGuffog, L. & Aittomäki, K., Oct 2020, In: Genetics In medicine. 22, 10, p. 1653-1666 14 p.

    Research output: Contribution to journalArticlepeer-review

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  • Prediction of contralateral breast cancer: external validation of risk calculators in 20 international cohorts

    Giardiello, D., Hauptmann, M., Steyerberg, E. W., Adank, M. A., Akdeniz, D., Blom, J. C., Blomqvist, C., Bojesen, S. E., Bolla, M. K., Brinkhuis, M., Chang-Claude, J., Czene, K., Devilee, P., Dunning, A. M., Easton, D. F., Eccles, D. M., Fasching, P. A., Figueroa, J., Flyger, H., Garcia-Closas, M. & 37 others, Haeberle, L., Haiman, C. A., Hall, P., Hamann, U., Hopper, J. L., Jager, A., Jakubowska, A., Jung, A., Keeman, R., Koppert, L. B., Kramer, I., Lambrechts, D., Le Marchand, L., Lindblom, A., Lubinski, J., Manoochehri, M., Mariani, L., Nevanlinna, H., Oldenburg, H. S. A., Pelders, S., Pharoah, P. D. P., Shah, M., Siesling, S., Smit, V. T. H. B. M., Southey, M. C., Tapper, W. J., Tollenaar, R. A. E. M., van den Broek, A. J., van Deurzen, C. H. M., van Leeuwen, F. E., van Ongeval, C., Van't Veer, L. J., Wang, Q., Wendt, C., Westenend, P. J., Hooning, M. J. & Schmidt, M. K., Jun 2020, In: Breast Cancer Research and Treatment. 181, 2, p. 423-434 12 p.

    Research output: Contribution to journalArticlepeer-review

  • SNPs in lncRNA regions and breast cancer risk

    Suvanto, M., Beesley, J., Blomqvist, C., Chenevix-Trench, G., Khan, S. & Nevanlinna, H., 2020, In: Frontiers in Genetics. 11, 16 p., 550.

    Research output: Contribution to journalArticlepeer-review

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  • The Spectrum of FANCM Protein Truncating Variants in European Breast Cancer Cases

    ENIGMA Consortium, ENIGMA Consortium, GENESIS Study Collaborators, SWE-BRCA Grp, Figlioli, G., Kvist, A., Tham, E., Muranen, T. A., Kiiski, J. & Nevanlinna, H., Feb 2020, In: Cancers. 12, 2, 10 p., 292.

    Research output: Contribution to journalArticlepeer-review

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  • Transcriptome-wide association study of breast cancer risk by estrogen-receptor status

    GEMO Study Collaborators, EMBRACE Collaborators, GC-HBOC Study Collaborators, ABCTB Investigators , HEBON Investigators, BCFR Investigators, OCGN Investigators, Feng, H., Gusev, A., Pasaniuc, B., Aittomäki, K., Blomqvist, C., Dunning, A. M., Kiiski, J. I., Muranen, T. A., Nevanlinna, H. & Zheng, W., Jul 2020, In: Genetic Epidemiology. 44, 5, p. 442-468 27 p.

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  • 2019

    Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis

    Breast Canc Assoc Consortium, NBCS Collaborators, Shu, X., Wu, L., Khankari, N. K., Blomqvist, C. & Nevanlinna, H., Jun 2019, In: International Journal of Epidemiology. 48, 3, p. 795-806 12 p.

    Research output: Contribution to journalArticleScientificpeer-review

  • BRCA1 mislocalization leads to aberrant DNA damage response in heterozygous ABRAXAS1 mutation carrier cells

    Bose, M., Sachsenweger, J., Laurila, N., Parplys, A. C., Willmann, J., Jungwirth, J., Groth, M., Rapakko, K., Nieminen, P., Friedl, T. W. P., Heiserich, L., Meyer, F., Tuppurainen, H., Peltoketo, H., Nevanlinna, H., Pylkäs, K., Borgmann, K., Wiesmüller, L., Winqvist, R. & Pospiech, H., 15 Dec 2019, In: Human Molecular Genetics. 28, 24, p. 4148-4161 14 p.

    Research output: Contribution to journalArticleScientificpeer-review

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  • Functional Analysis and Fine Mapping of the 9p22.2 Ovarian Cancer Susceptibility Locus

    Ovarian Canc Asso Consortium, AOCS Management Grp, Buckley, M. A., Butzow, R., Nevanlinna, H., Pelttari, L. M. & Freedman, M. L., 1 Feb 2019, In: Cancer Research. 79, 3, p. 467-481 15 p.

    Research output: Contribution to journalArticlepeer-review

  • Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk

    Yang, Y., Wu, L., Shu, X., Lu, Y., Shu, X-O., Cai, Q., Beeghly-Fadiel, A., Li, B., Ye, F., Berchuck, A., Anton-Culver, H., Banerjee, S., Benitez, J., Bjorge, L., Brenton, J. D., Butzow, R., Campbell, I. G., Chang-Claude, J., Chen, K., Cook, L. S. & 80 others, Cramer, D. W., defazio, A., Dennis, J., Doherty, J. A., Doerk, T., Eccles, D. M., Edwards, D. V., Fasching, P. A., Fortner, R. T., Gayther, S. A., Giles, G. G., Glasspool, R. M., Goode, E. L., Goodman, M. T., Gronwald, J., Harris, H. R., Heitz, F., Hildebrandt, M. A., Hogdall, E., Hogdall, C. K., Huntsman, D. G., Kar, S. P., Karlan, B. Y., Kelemen, L. E., Kiemeney, L. A., Kjaer, S. K., Koushik, A., Lambrechts, D., Le, N. D., Levine, D. A., Massuger, L. F., Matsuo, K., May, T., McNeish, I. A., Menon, U., Modugno, F., Monteiro, A. N., Moorman, P. G., Moysich, K. B., Ness, R. B., Nevanlinna, H., Olsson, H., Onland-Moret, N. C., Park, S. K., Paul, J., Pearce, C. L., Pejovic, T., Phelan, C. M., Pike, M. C., Ramus, S. J., Riboli, E., Rodriguez-Antona, C., Romieu, I., Sandler, D. P., Schildkraut, J. M., Setiawan, V. W., Shan, K., Siddiqui, N., Sieh, W., Stampfer, M. J., Sutphen, R., Swerdlow, A. J., Szafron, L. M., Teo, S. H., Tworoger, S. S., Tyrer, J. P., Webb, P. M., Wentzensen, N., White, E., Willett, W. C., Wolk, A., Woo, Y. L., Wu, A. H., Yan, L., Yannoukakos, D., Chenevix-Trench, G., Sellers, T. A., Pharoah, P. D. P., Zheng, W. & Long, J., 1 Feb 2019, In: Cancer Research. 79, 3, p. 505-517 13 p.

    Research output: Contribution to journalArticlepeer-review

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  • Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer

    GC-HBOC Study Collaborators, GEMO Study Collaborators, EMBRACE Collaborators, HEBON Investigators, BCFR Investigators, ABCTB Investigators , Ferreira, M. A., Gamazon, E. R., Aittomäki, K., Blomqvist, C., Kiiski, J. I. & Nevanlinna, H., 15 Apr 2019, In: Nature Communications. 10, 18 p., 1741.

    Research output: Contribution to journalArticlepeer-review

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  • Genome-wide association study of germline variants and breast cancer-specific mortality

    NBCS Collaborators, Escala-Garcia, M., Guo, Q., Doerk, T., Blomqvist, C., Khan, S., Kiiski, J. I. & Nevanlinna, H., 19 Mar 2019, In: British Journal of Cancer. 120, 6, p. 647-657 11 p.

    Research output: Contribution to journalArticleScientificpeer-review

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  • Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study

    GEMO Study Collaborators, HEBON, EMBRACE, Qian, F., Wang, S. & Aittomäki, K., Apr 2019, In: Journal of the National Cancer Institute. 111, 4, p. 350-364 15 p., 132.

    Research output: Contribution to journalArticlepeer-review

  • Large scale multifactorial likelihood quantitative analysis of BRCA1 and BRCA2 variants: An ENIGMA resource to support clinical variant classification

    Parsons, M. T., Tudini, E., Li, H., Hahnen, E., Wappenschmidt, B., Feliubadaló, L., Aalfs, C. M., Agata, S., Aittomäki, K., Alducci, E., Alonso-Cerezo, M. C., Arnold, N., Auber, B., Austin, R., Azzollini, J., Balmaña, J., Barbieri, E., Bartram, C. R., Blanco, A., Blümcke, B. & 197 others, Bonache, S., Bonanni, B., Borg, Å., Bortesi, B., Brunet, J., Bruzzone, C., Bucksch, K., Cagnoli, G., Caldés, T., Caliebe, A., Caligo, M. A., Calvello, M., Capone, G. L., Caputo, S. M., Carnevali, I., Carrasco, E., Caux-Moncoutier, V., Cavalli, P., Cini, G., Clarke, E. M., Concolino, P., Cops, E. J., Cortesi, L., Couch, F. J., Darder, E., de la Hoya, M., Dean, M., Debatin, I., del Valle, J., Delnatte, C., Derive, N., Diez, O., Ditsch, N., Domchek, S. M., Dutrannoy, V., Eccles, D. M., Ehrencrona, H., Enders, U., Evans, D. G., Faust, U., Felbor, U., Feroce, I., Fine, M., Galvao, H. C. R., Gambino, G., Gehrig, A., Gensini, F., Gerdes, A-M., Germani, A., Giesecke, J., Gismondi, V., Gómez, C., Gómez Garcia, E. B., González, S., Grau, E., Grill, S., Gross, E., Guerrieri-Gonzaga, A., Guillaud-Bataille, M., Gutiérrez-Enríquez, S., Haaf, T., Hackmann, K., Hansen, T. V. O., Harris, M., Hauke, J., Heinrich, T., Hellebrand, H., Herold, K. N., Honisch, E., Horvath, J., Houdayer, C., Hübbel, V., Iglesias, S., Izquierdo, A., James, P. A., Janssen, L. A. M., Jeschke, U., Kaulfuß, S., Keupp, K., Kiechle, M., Kölbl, A., Krieger, S., Kruse, T. A., Kvist, A., Lalloo, F., Larsen, M., Lattimore, V. L., Lautrup, C., Ledig, S., Leinert, E., Lewis, A. L., Lim, J., Loeffler, M., López-Fernández, A., Lucci-Cordisco, E., Maass, N., Manoukian, S., Marabelli, M., Matricardi, L., Meindl, A., Michelli, R. D., Moghadasi, S., Moles-Fernández, A., Montagna, M., Montalban, G., Monteiro, A. N., Montes, E., Mori, L., Moserle, L., Müller, C. R., Mundhenke, C., Naldi, N., Nathanson, K. L., Navarro, M., Nevanlinna, H., Nichols, C. B., Niederacher, D., Nielsen, H. R., Ong, K., Pachter, N., Palmero, E. I., Papi, L., Pedersen, I. S., Peissel, B., Pérez-Segura, P., Pfeifer, K., Pineda, M., Pohl-Rescigno, E., Poplawski, N. K., Porfirio, B., Quante, A. S., Ramser, J., Reis, R. M., Revillion, F., Rhiem, K., Riboli, B., Ritter, J., Rivera, D., Rofes, P., Rump, A., Salinas, M., Sánchez de Abajo, A. M., Schmidt, G., Schoenwiese, U., Seggewiß, J., Solanes, A., Steinemann, D., Stiller, M., Stoppa-Lyonnet, D., Sullivan, K. J., Susman, R., Sutter, C., Tavtigian, S. V., Teo, S. H., Teulé, A., Thomassen, M., Tibiletti, M. G., Tognazzo, S., Toland, A. E., Tornero, E., Törngren, T., Torres-Esquius, S., Toss, A., Trainer, A. H., van Asperen, C. J., van Mackelenbergh, M. T., Varesco, L., Vargas-Parra, G., Varon, R., Vega, A., Velasco, Á., Vesper, A-S., Viel, A., Vreeswijk, M. P. G., Wagner, S. A., Waha, A., Walker, L. C., Walters, R. J., Wang-Gohrke, S., Weber, B. H. F., Weichert, W., Wieland, K., Wiesmüller, L., Witzel, I., Wöckel, A., Woodward, E. R., Zachariae, S., Zampiga, V., Zeder-Göß, C., Investigators, KC., Lázaro, C., De Nicolo, A., Radice, P., Engel, C., Schmutzler, R. K., Goldgar, D. E. & Spurdle, A. B., Sep 2019, In: Human Mutation. 40, 9, p. 1557-1578 22 p.

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  • Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers

    kConFab Investigators, HEBON Investigators, GEMO Study Collaborators, EMBRACE Collaborators, CIMBA, Qian, F., Rookus, M. A., Leslie, G., Aittomaki, K. & Nevanlinna, H., 16 Jul 2019, In: British Journal of Cancer. 121, 2, p. 180-192 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Metaplastic carcinoma of the breast: Prognosis and response to systemic treatment in metastatic disease

    Takala, S., Heikkilä, P., Nevanlinna, H., Blomqvist, C. & Mattson, J., 2019, In: Breast Journal. 25, 3, p. 418-424 7 p.

    Research output: Contribution to journalArticlepeer-review

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  • Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

    Mavaddat, N., Michailidou, K., Dennis, J., Lush, M., Fachal, L., Lee, A., Tyrer, J. P., Chen, T-H., Wang, Q., Bolla, M. K., Yang, X., Adank, M. A., Ahearn, T., Aittomäki, K., Allen, J., Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., Arndt, V., Aronson, K. J. & 249 others, Auer, P. L., Auvinen, P., Barrdahl, M., Beane Freeman, L. E., Beckmann, M. W., Behrens, S., Benitez, J., Bermisheva, M., Bernstein, L., Blomqvist, C., Bogdanova, N. V., Bojesen, S. E., Bonanni, B., Børresen-Dale, A-L., Brauch, H., Bremer, M., Brenner, H., Brentnall, A., Brock, I. W., Brooks-Wilson, A., Brucker, S. Y., Brüning, T., Burwinkel, B., Campa, D., Carter, B. D., Castelao, J. E., Chanock, S. J., Chlebowski, R., Christiansen, H., Clarke, C. L., Collée, J. M., Cordina-Duverger, E., Cornelissen, S., Couch, F. J., Cox, A., Cross, S. S., Czene, K., Daly, M. B., Devilee, P., Dörk, T., dos-Santos-Silva, I., Dumont, M., Durcan, L., Dwek, M., Eccles, D. M., Ekici, A. B., Eliassen, A. H., Ellberg, C., Engel, C., Eriksson, M., Evans, D. G., Fasching, P. A., Figueroa, J., Fletcher, O., Flyger, H., Försti, A., Fritschi, L., Gabrielson, M., Gago-Dominguez, M., Gapstur, S. M., García-Sáenz, J. A., Gaudet, M. M., Georgoulias, V., Giles, G. G., Gilyazova, I. R., Glendon, G., Goldberg, M. S., Goldgar, D. E., González-Neira, A., Grenaker Alnæs, G. I., Grip, M., Gronwald, J., Grundy, A., Guénel, P., Haeberle, L., Hahnen, E., Haiman, C. A., Håkansson, N., Hamann, U., Hankinson, S. E., Harkness, E. F., Hart, S. N., He, W., Hein, A., Heyworth, J., Hillemanns, P., Hollestelle, A., Hooning, M. J., Hoover, R. N., Hopper, J. L., Howell, A., Huang, G., Humphreys, K., Hunter, D. J., Jakimovska, M., Jakubowska, A., Janni, W., John, E. M., Johnson, N., Jones, M. E., Jukkola-Vuorinen, A., Jung, A., Kaaks, R., Kaczmarek, K., Kataja, V., Keeman, R., Kerin, M. J., Khusnutdinova, E., Kiiski, J. I., Knight, J. A., Ko, Y-D., Kosma, V-M., Koutros, S., Kristensen, V. N., Krüger, U., Kühl, T., Lambrechts, D., Le Marchand, L., Lee, E., Lejbkowicz, F., Lilyquist, J., Lindblom, A., Lindström, S., Lissowska, J., Lo, W-Y., Loibl, S., Long, J., Lubiński, J., Lux, M. P., MacInnis, R. J., Maishman, T., Makalic, E., Maleva Kostovska, I., Mannermaa, A., Manoukian, S., Margolin, S., Martens, J. W. M., Martinez, M. E., Mavroudis, D., McLean, C., Meindl, A., Menon, U., Middha, P., Miller, N., Moreno, F., Mulligan, A. M., Mulot, C., Muñoz-Garzon, V. M., Neuhausen, S. L., Nevanlinna, H., Neven, P., Newman, W. G., Nielsen, S. F., Nordestgaard, B. G., Norman, A., Offit, K., Olson, J. E., Olsson, H., Orr, N., Pankratz, V. S., Park-Simon, T-W., Perez, J. I. A., Pérez-Barrios, C., Peterlongo, P., Peto, J., Pinchev, M., Plaseska-Karanfilska, D., Polley, E. C., Prentice, R., Presneau, N., Prokofyeva, D., Purrington, K., Pylkäs, K., Rack, B., Radice, P., Rau-Murthy, R., Rennert, G., Rennert, H. S., Rhenius, V., Robson, M., Romero, A., Ruddy, K. J., Ruebner, M., Saloustros, E., Sandler, D. P., Sawyer, E. J., Schmidt, D. F., Schmutzler, R. K., Schneeweiss, A., Schoemaker, M. J., Schumacher, F., Schürmann, P., Schwentner, L., Scott, C., Scott, R. J., Seynaeve, C., Shah, M., Sherman, M. E., Shrubsole, M. J., Shu, X-O., Slager, S., Smeets, A., Sohn, C., Soucy, P., Southey, M. C., Spinelli, J. J., Stegmaier, C., Stone, J., Swerdlow, A. J., Tamimi, R. M., Tapper, W. J., Taylor, J. A., Terry, M. B., Thöne, K., Tollenaar, R. A. E. M., Tomlinson, I., Truong, T., Tzardi, M., Ulmer, H-U., Untch, M., Vachon, C. M., van Veen, E. M., Vijai, J., Weinberg, C. R., Wendt, C., Whittemore, A. S., Wildiers, H., Willett, W., Winqvist, R., Wolk, A., Yang, X. R., Yannoukakos, D., Zhang, Y., Zheng, W., Ziogas, A., Dunning, A. M., Thompson, D. J., Chenevix-Trench, G., Chang-Claude, J., Schmidt, M. K., Hall, P., Milne, R. L., Pharoah, P. D. P., Antoniou, A. C., Chatterjee, N., Kraft, P., García-Closas, M., Simard, J. & Easton, D. F., 3 Jan 2019, In: American Journal of Human Genetics. 104, 1, p. 21-34 14 p.

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  • Prediction and clinical utility of a contralateral breast cancer risk model

    Giardiello, D., Steyerberg, E. W., Hauptmann, M., Adank, M. A., Akdeniz, D., Blomqvist, C., Bojesen, S. E., Bolla, M. K., Brinkhuis, M., Chang-Claude, J., Czene, K., Devilee, P., Dunning, A. M., Easton, D. F., Eccles, D. M., Fasching, P. A., Figueroa, J., Flyger, H., Garciá-Closas, M., Haeberle, L. & 35 others, Haiman, C. A., Hall, P., Hamann, U., Hopper, J. L., Jager, A., Jakubowska, A., Jung, A., Keeman, R., Kramer, I., Lambrechts, D., Le Marchand, L., Lindblom, A., Lubiński, J., Manoochehri, M., Mariani, L., Nevanlinna, H., Oldenburg, H. S. A., Pelders, S., Pharoah, P. D. P., Shah, M., Siesling, S., Smit, V. T. H. B. M., Southey, M. C., Tapper, W. J., Tollenaar, R. A. E. M., Van Den Broek, A. J., Van Deurzen, C. H. M., Van Leeuwen, F. E., Van Ongeval, C., Van't Veer, L. J., Wang, Q., Wendt, C., Westenend, P. J., Hooning, M. J. & Schmidt, M. K., 17 Dec 2019, In: Breast Cancer Research. 21, 1, 13 p., 144.

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  • Recurrent moderate-risk mutations in Finnish breast and ovarian cancer patients

    Nurmi, A., Muranen, T. A., Pelttari, L. M., Kiiski, J. I., Heikkinen, T., Lehto, S., Kallioniemi, A., Schleutker, J., Bützow, R., Blomqvist, C., Aittomäki, K. & Nevanlinna, H., 15 Nov 2019, In: International Journal of Cancer. 145, 10, p. 2692-2700 9 p.

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  • Shared heritability and functional enrichment across six solid cancers

    Jiang, X., Finucane, H. K., Schumacher, F. R., Schmit, S. L., Tyrer, J. P., Han, Y., Michailidou, K., Lesseur, C., Kuchenbaecker, K. B., Dennis, J., Conti, D. V., Casey, G., Gaudet, M. M., Huyghe, J. R., Albanes, D., Aldrich, M. C., Andrew, A. S., Andrulis, I. L., Anton-Culver, H., Antoniou, A. C. & 313 others, Antonenkova, N. N., Arnold, S. M., Aronson, K. J., Arun, B. K., Bandera, E. V., Barkardottir, R. B., Barnes, D. R., Batra, J., Beckmann, M. W., Benitez, J., Benlloch, S., Berchuck, A., Berndt, S. I., Bickeboeller, H., Bien, S. A., Blomqvist, C., Boccia, S., Bogdanova, N. V., Bojesen, S. E., Bolla, M. K., Brauch, H., Brenner, H., Brenton, J. D., Brook, M. N., Brunet, J., Brunnstrom, H., Buchanan, D. D., Burwinkel, B., Butzow, R., Cadoni, G., Caldes, T., Caligo, M. A., Campbell, I., Campbell, P. T., Cancel-Tassin, G., Cannon-Albright, L., Campa, D., Caporaso, N., Carvalho, A. L., Chan, A. T., Chang-Claude, J., Chanock, S. J., Chen, C., Christiani, D. C., Claes, K. B. M., Claessens, F., Clements, J., Collee, J. M., Correa, M. C., Couch, F. J., Cox, A., Cunningham, J. M., Cybulski, C., Czene, K., Daly, M. B., defazio, A., Devilee, P., Diez, O., Gago-Dominguez, M., Donovan, J. L., Doerk, T., Duell, E. J., Dunning, A. M., Dwek, M., Eccles, D. M., Edlund, C. K., Edwards, D. R. V., Ellberg, C., Evans, D. G., Fasching, P. A., Ferris, R. L., Liloglou, T., Figueiredo, J. C., Fletcher, O., Fortner, R. T., Fostira, F., Franceschi, S., Friedman, E., Gallinger, S. J., Ganz, P. A., Garber, J., Garcia-Saenz, J. A., Gayther, S. A., Giles, G. G., Godwin, A. K., Goldberg, M. S., Goldgar, D. E., Goode, E. L., Goodman, M. T., Goodman, G., Grankvist, K., Greene, M. H., Gronberg, H., Gronwald, J., Guenel, P., Hakansson, N., Hall, P., Hamann, U., Hamdy, F. C., Hamilton, R. J., Hampe, J., Haugen, A., Heitz, F., Herrero, R., Hillemanns, P., Hoffmeister, M., Hogdall, E., Hong, Y-C., Hopper, J. L., Houlston, R., Hulick, P. J., Hunter, D. J., Huntsman, D. G., Idos, G., Imyanitov, E. N., Ingles, S. A., Isaacs, C., Jakubowska, A., James, P., Jenkins, M. A., Johansson, M., Johansson, M., John, E. M., Joshi, A. D., Kaneva, R., Karlan, B. Y., Kelemen, L. E., Kuhl, T., Khaw, K-T., Khusnutdinova, E., Kibel, A. S., Kiemeney, L. A., Kim, J., Kjaer, S. K., Knight, J. A., Kogevinas, M., Kote-Jarai, Z., Koutros, S., Kristensen, V. N., Kupryjanczyk, J., Lacko, M., Lam, S., Lambrechts, D., Landi, M. T., Lazarus, P., Le, N. D., Lee, E., Lejbkowicz, F., Lenz, H-J., Leslie, G., Lessel, D., Lester, J., Levine, D. A., Li, L., Li, C. I., Lindblom, A., Lindor, N. M., Liu, G., Loupakis, F., Lubinski, J., Maehle, L., Maier, C., Mannermaa, A., Le Marchand, L., Margolin, S., May, T., McGuffog, L., Meindl, A., Middha, P., Miller, A., Milne, R. L., MacInnis, R. J., Modugno, F., Montagna, M., Moreno, V., Moysich, K. B., Mucci, L., Muir, K., Mulligan, A. M., Nathanson, K. L., Neal, D. E., Ness, A. R., Neuhausen, S. L., Nevanlinna, H., Newcomb, P. A., Newcomb, L. F., Nielsen, F. C., Nikitina-Zake, L., Nordestgaard, B. G., Nussbaum, R. L., Offit, K., Olah, E., Al Olama, A. A., Olopade, O. I., Olshan, A. F., Olsson, H., Osorio, A., Pandha, H., Park, J. Y., Pashayan, N., Parsons, M. T., Pejovic, T., Penney, K. L., Peters, W. H. M., Phelan, C. M., Phipps, A. I., Plaseska-Karanfilska, D., Pring, M., Prokofyeva, D., Radice, P., Stefansson, K., Ramus, S. J., Raskin, L., Rennert, G., Rennert, H. S., van Rensburg, E. J., Riggan, M. J., Risch, H. A., Risch, A., Roobol, M. J., Rosenstein, B. S., Rossing, M. A., De Ruyck, K., Saloustros, E., Sandler, D. P., Sawyer, E. J., Schabath, M. B., Schleutker, J., Schmidt, M. K., Setiawan, V. W., Shen, H., Siegel, E. M., Sieh, W., Singer, C. F., Slattery, M. L., Sorensen, K. D., Southey, M. C., Spurdle, A. B., Stanford, J. L., Stevens, V. L., Stintzing, S., Stone, J., Sundfeldt, K., Sutphen, R., Swerdlow, A. J., Tajara, E. H., Tangen, C. M., Tardon, A., Taylor, J. A., Teare, M. D., Teixeira, M. R., Terry, M. B., Terry, K. L., Thibodeau, S. N., Thomassen, M., Bjorge, L., Tischkowitz, M., Toland, A. E., Torres, D., Townsend, P. A., Travis, R. C., Tung, N., Tworoger, S. S., Ulrich, C. M., Usmani, N., Vachon, C. M., Van Nieuwenhuysen, E., Vega, A., Aguado-Barrera, M. E., Wang, Q., Webb, P. M., Weinberg, C. R., Weinstein, S., Weissler, M. C., Weitzel, J. N., West, C. M. L., White, E., Whittemore, A. S., Wichmann, H-E., Wiklund, F., Winqvist, R., Wolk, A., Woll, P., Woods, M., Wu, A. H., Wu, X., Yannoukakos, D., Zheng, W., Zienolddiny, S., Ziogas, A., Zorn, K. K., Lane, J. M., Saxena, R., Thomas, D., Hung, R. J., Diergaarde, B., Mckay, J., Peters, U., Hsu, L., Garcia-Closas, M., Eeles, R. A., Chenevix-Trench, G., Brennan, P. J., Haiman, C. A., Simard, J., Easton, D. F., Gruber, S. B., Pharoah, P. D. P., Price, A. L., Pasaniuc, B., Amos, C. I., Kraft, P. & Lindstrom, S., 25 Jan 2019, In: Nature Communications. 10, 23 p., 431.

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  • The FANCM: p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

    ABCTB Investigators , GEMO Study Collaborators, KConFab, Figlioli, G., Bogliolo, M., Kiiski, J., Muranen, T. A., Aittomäki, K., Blomqvist, C. & Nevanlinna, H., 1 Nov 2019, In: Breast Cancer. 5, 14 p., 38.

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  • Two truncating variants in FANCC and breast cancer risk

    ABCTB Investigators , NBCS Collaborators, Dörk, T., Peterlongo, P. & Mannermaa, A., 29 Aug 2019, In: Scientific Reports. 9, 14 p., 12524.

    Research output: Contribution to journalArticleScientificpeer-review

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  • 2018

    Adult height is associated with increased risk of ovarian cancer: a Mendelian randomisation study

    Australian Ovarian Canc Study Grp , Ovarian Canc Assoc Consortium, Dixon-Suen, S. C., Nagle, C. M., Butzow, R., Nevanlinna, H., Pelttari, L. M., Leminen, A. & Webb, P. M., Apr 2018, In: British Journal of Cancer. 118, 8, p. 1123-1129 7 p.

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    Open Access
  • A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk

    Lu, Y., Beeghly-Fadiel, A., Wu, L., Guo, X., Li, B., Schildkraut, J. M., Im, H. K., Chen, Y. A., Permuth, J. B., Reid, B. M., Teer, J. K., Moysich, K. B., Andrulis, I. L., Anton-Culver, H., Arun, B. K., Bandera, E. V., Barkardottir, R. B., Barnes, D. R., Benitez, J., Bjorge, L. & 124 others, Brenton, J., Butzow, R., Caldes, T., Caligo, M. A., Campbell, I., Chang-Claude, J., Claes, K. B. M., Couch, F. J., Cramer, D., Daly, M. B., deFazio, A., Dennis, J., Diez, O., Domchek, S. M., Doerk, T., Easton, D. F., Eccles, D. M., Fasching, P. A., Fortner, R. T., Fountzilas, G., Friedman, E., Ganz, P. A., Garber, J., Giles, G. G., Godwin, A. K., Goldgar, D. E., Goodman, M. T., Greene, M. H., Gronwald, J., Hamann, U., Heitz, F., Hildebrandt, M. A. T., Hogdall, C. K., Hollestelle, A., Hulick, P. J., Huntsman, D. G., Imyanitov, E. N., Isaacs, C., Jakubowska, A., James, P., Karlan, B. Y., Kelemen, L. E., Kiemeney, L. A., Kjaer, S. K., Kwong, A., Le, N. D., Leslie, G., Lesueur, F., Levine, D. A., Mattiello, A., May, T., McGuffog, L., McNeish, I. A., Merritt, M. A., Modugno, F., Montagna, M., Neuhausen, S. L., Nevanlinna, H., Nielsen, F. C., Nikitina-Zake, L., Nussbaum, R. L., Offit, K., Olah, E., Olopade, O. I., Olson, S. H., Olsson, H., Osorio, A., Park, S. K., Parsons, M. T., Peeters, P. H. M., Pejovic, T., Peterlongo, P., Phelan, C. M., Pujana, M. A., Ramus, S. J., Rennert, G., Risch, H., Rodriguez, G. C., Rodriguez-Antona, C., Romieu, I., Rookus, M. A., Rossing, M. A., Rzepecka, I. K., Sandler, D. P., Schmutzler, R. K., Setiawan, V. W., Sharma, P., Sieh, W., Simard, J., Singer, C. F., Song, H., Southey, M. C., Spurdle, A. B., Sutphen, R., Swerdlow, A. J., Teixeira, M. R., Teo, S. H., Thomassen, M., Tischkowitz, M., Toland, A. E., Trichopoulou, A., Tung, N., Tworoger, S. S., van Rensburg, E. J., Vanderstichele, A., Vega, A., Edwards, D. V., Webb, P. M., Weitzel, J. N., Wentzensen, N., White, E., Wolk, A., Wu, A. H., Yannoukakos, D., Zorn, K. K., Gayther, S. A., Antoniou, A. C., Berchuck, A., Goode, E. L., Chenevix-Trench, G., Sellers, T. A., Pharoah, P. D. P., Zheng, W. & Long, J., 15 Sep 2018, In: Cancer Research. 78, 18, p. 5419-5430 12 p.

    Research output: Contribution to journalArticlepeer-review

  • A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer

    NBCS Collaborators & kConFab-AOCS Investigators, Jul 2018, In: Nature Genetics. 50, 7, p. 968-+ 13 p.

    Research output: Contribution to journalArticlepeer-review

  • E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium

    Horne, H. N., Oh, H., Sherman, M. E., Palakal, M., Hewitt, S. M., Schmidt, M. K., Milne, R. L., Hardisson, D., Benitez, J., Blomqvist, C., Bolla, M. K., Brenner, H., Chang-Claude, J., Cora, R., Couch, F. J., Cuk, K., Devilee, P., Easton, D. F., Eccles, D. M., Eilber, U. & 30 others, Hartikainen, J. M., Heikkilä, P., Holleczek, B., Hooning, M. J., Jones, M., Keeman, R., Mannermaa, A., Martens, J. W. M., Muranen, T. A., Nevanlinna, H., Olson, J. E., Orr, N., Perez, J. I. A., Pharoah, P. D. P., Ruddy, K. J., Saum, K-U., Schoemaker, M. J., Seynaeve, C., Sironen, R., Smit, V. T. H. B. M., Swerdlow, A. J., Tengstrom, M., Thomas, A. S., Timmermans, A. M., Tollenaar, R. A. E. M., Troester, M. A., van Asperen, C. J., van Deurzen, C. H. M., Van Leeuwen, F. F. & Van'tVeer, L. J., 26 Apr 2018, In: Scientific Reports. 8, 11 p., 6574.

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