Research output per year
Research output per year
Personal profile
Education/Academic qualification
Msc. Pharm.
Fields of Science
- 3121 General medicine, internal medicine and other clinical medicine
- Clinical Pharmacology
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Studies on the role of glucuronide metabolites as mechanism-based CYP enzyme inhibitors
Kahma, H., 2025, Helsinki: Helsingin yliopisto. 121 p.Research output: Thesis › Doctoral Thesis › Collection of Articles
Open Access -
In vitro assessment of inhibitory effects of kinase inhibitors on CYP2C9, 3A and 1A2: Prediction of drug-drug interaction risk with warfarin and direct oral anticoagulants
Jin, S., Paludetto, M.-N., Kurkela, M., Kahma, H., Neuvonen, M., Xiang, X., Cai, W. & Backman, J. T., 1 Dec 2024, In: European Journal of Pharmaceutical Sciences. 203, 17 p., 106884.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Screening of 16 major drug glucuronides for time-dependent inhibition of nine drug-metabolizing CYP enzymes – detailed studies on CYP3A inhibitors
Kahma, H., Paludetto, M.-N., Neuvonen, M., Kurkela, M., Filppula, A. M., Niemi, M. & Backman, J. T., 1 Jul 2024, In: European Journal of Pharmaceutical Sciences. 198, 12 p., 106735.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Carvedilol is a time-dependent inhibitor of CYP3A
Kahma, H., Paludetto, M.-N. I. A., Neuvonen, M., Kurkela, M., Filppula, A., Niemi, M. & Backman, J., 14 Jun 2023.Research output: Conference materials › Poster
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Elucidating the drug–drug interaction potential of hydroxychloroquine metabolites due to direct and time-dependent inhibition of CYP3A In: ABSTRACTS FROM SECOND NORDIC CONFERENCE ON PERSONALIZED MEDICINE 2023 IN TURKU, FINLAND
Kahma, H., Paludetto, M.-N. I. A., Neuvonen, M., Kurkela, M., Filppula, A., Niemi, M. & Backman, J., 1 Jun 2023, In: Basic & Clinical Pharmacology & Toxicology.Research output: Contribution to journal › Meeting Abstract
Projects
- 2 Finished
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JUSELIUS 22-25 BACKMAN JANNE
Backman, J. (Project manager), Kahma, H. (Participant), Kurkela, M. (Participant) & Paludetto, M.-N. I. A. (Participant)
Sigrid Juséliuksen Säätiö @003701165704@
01/05/2022 → 31/12/2025
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
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Academy of Finland Project Funding: Mechanism-Based Inactivation of Cytochrome P450 (Palautumaton sytokromi P450-entsyymien esto ja kliinisesti merkittävät lääkeaineyhteisvaikutukset: Yhteisvaikutuksia in vitro tiedosta ennustavien menetelmien kehittäminen)
Backman, J. (Project manager), Niemi, M. (Principal Investigator), Tornio, A. (Participant), Filppula, A. M. (Participant), Neuvonen, P. (Principal Investigator), Neuvonen, M. (Participant), Launiainen, T. (Participant), Kahma, H. (Participant), Kaartinen, T. (Participant) & Itkonen, M. (Participant)
01/09/2014 → 31/08/2018
Project: Research project
Prizes
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Best three minute thesis presentation, FPDP-C section
Kahma, H. (Recipient), 20 Aug 2015
Prize: Prizes and awards
Activities
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The 50th Gordon Research Conference on Drug Metabolism
Kahma, H. (Poster Presentation)
10 Jul 2022 → 15 Jul 2022Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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12th International ISSX meeting
Kahma, H. (Poster Presentation)
28 Jul 2019 → 31 Jul 2019Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Joint 25th Anniversary Symposium of Teratology Information Service and Finnish Society of Clinical Pharmacology
Kahma, H. (Poster Presentation)
4 Dec 2019Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Pharmacogenetics at the University of Helsinki
Kahma, H. (Speaker: Presenter)
28 May 2019 → 29 May 2019Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Improving Rational Pharmacotherapy - 50 years of Clinical Pharmacology in Finland
Kahma, H. (Member of organizing committee)
8 Nov 2018 → 9 Nov 2018Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars