Hossam Montaser

Publications

Research output per year 2020 2022 2023 2024 2024

• 10 Article
• 1 Chapter
• 1 Comment/debate

Research output per year

Research output per year

Search results

• 2024

  Non-invasive quantification of stem cell-derived islet graft size and composition

  Lithovius, V., Lahdenpohja, S., Ibrahim, H., Saarimäki-Vire, J., Uusitalo, L., Montaser, H., Mikkola, K., Yim, C. B., Keller, T., Rajander, J., Balboa, D., Barsby, T., Solin, O., Nuutila, P., Grönroos, T. J. & Otonkoski, T., 2024, In: Diabetologia. 18 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell function

  Ibrahim, H., Balboa, D., Saarimäki-Vire, J., Montaser, H., Dyachok, O., Lund, P. E., Omar-Hmeadi, M., Kvist, J., Dwivedi, O. P., Lithovius, V., Barsby, T., Chandra, V., Eurola, S., Ustinov, J., Tuomi, T., Miettinen, P. J., Barg, S., Tengholm, A. & Otonkoski, T., 2024, In: Diabetologia. 67, p. 1642–1662 21 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Thymidylate synthase disruption to limit cell proliferation in cell therapies

  Maldonado Sartori, R., Montaser, H., Soppa, I. S. E., Eurola, S., Juutila, J. H., Balaz, M., Puttonen, H., Otonkoski, T., Saarimäki-Vire, J. & Wartiovaara, K., 7 Aug 2024, In: Molecular therapy. 32, 8, p. 2535-2548 14 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2023

  Aberrant metabolite trafficking and fuel sensitivity in human pluripotent stem cell-derived islets

  Barsby, T., Vähäkangas, E., Ustinov, J., Montaser, H., Ibrahim, H., Lithovius, V., Kuuluvainen, E., Chandra, V., Saarimäki-Vire, J., Katajisto, P., Hietakangas, V. & Otonkoski, T., 29 Aug 2023, In: Cell Reports. 42, 8, 17 p., 112970.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Primate-specific ZNF808 is essential for pancreatic development in humans

  Pancreatic Agenesis Gene Discovery, De Franco, E., Owens, N. D. L., Montaser, H., Wakeling, M. N., Saarimäki-Vire, J., Triantou, A., Ibrahim, H., Balboa, D., Caswell, R. C., Jennings, R. E., Kvist, J. A., Johnson, M. B., Muralidharan, S., Ellard, S., Wright, C. F., Maddirevula, S., Alkuraya, F. S., Hanley, N. A., Flanagan, S. E., & 3 othersOtonkoski, T., Hattersley, A. T. & Imbeault, M., 2023, In: Nature Genetics. 55, p. 2075–2081 30 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2022

  Differentiating functional human islet-like aggregates from pluripotent stem cells

  Barsby, T., Ibrahim, H., Lithovius, V., Montaser, H., Balboa, D., Vähäkangas, E., Chandra, V., Saarimäki-Vire, J. & Otonkoski, T., 16 Dec 2022, In: STAR protocols. 3, 4, 101711.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells

  Balboa, D., Barsby, T., Lithovius, V., Saarimäki-Vire, J., Omar-Hmeadi, M., Dyachok, O., Montaser, H., Lund, P-E., Yang, M., Ibrahim, H., Näätänen, A., Chandra, V., Vihinen, H., Jokitalo, E., Kvist, J., Ustinov, J., Nieminen, A., Kuuluvainen, E., Hietakangas, V., Katajisto, P., & 5 othersLau, J., Carlsson, P-O., Barg, S., Tengholm, A. & Otonkoski, T., Jul 2022, In: Nature Biotechnology. 40, p. 1042–1055 21 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• The type 1 diabetes gene TYK2 regulates beta-cell development and its responses to interferon-alpha

  Chandra, V., Ibrahim, H., Halliez, C., Prasad, R. B., Vecchio, F., Dwivedi, O. P., Kvist, J., Balboa, D., Saarimäki-Vire, J., Montaser, H., Barsby, T., Lithovius, V., Artner, I., Gopalakrishnan, S., Groop, L., Mallone, R., Eizirik, D. L. & Otonkoski, T., 26 Oct 2022, In: Nature Communications. 13, 1, 16 p., 6363.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2021

  Loss of MANF Causes Childhood-Onset Syndromic Diabetes Due to Increased Endoplasmic Reticulum Stress

  Montaser, H., Patel, K. A., Balboa, D., Ibrahim, H., Lithovius, V., Näätänen, A., Chandra, V., Demir, K., Acar, S., Ben-Omran, T., Colclough, K., Locke, J. M., Wakeling, M., Lindahl, M., Hattersley, A. T., Saarimaki-Vire, J. & Otonkoski, T., Apr 2021, In: Diabetes. 70, 4, p. 1006-1018 13 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2020

  YIPF5 mutations cause neonatal diabetes and microcephaly through endoplasmic reticulum stress

  De Franco, E., Lytrivi, M., Ibrahim, H., Montaser, H., Wakeling, M. N., Fantuzzi, F., Patel, K., Demarez, C., Cai, Y., Igoillo-Esteve, M., Cosentino, C., Lithovius, V., Vihinen, H., Jokitalo, E., Laver, T. W., Johnson, M. B., Sawatani, T., Shakeri, H., Pachera, N., Haliloglu, B., & 19 othersOzbek, M. N., Unal, E., Yildirim, R., Godbole, T., Yildiz, M., Aydin, B., Bilheu, A., Suzuki, I., Flanagan, S. E., Vanderhaeghen, P., Senee, V., Julier, C., Marchetti, P., Eizirik, D. L., Ellard, S., Saarimäki-Vire, J., Otonkoski, T., Cnop, M. & Hattersley, A. T., 1 Dec 2020, In: Journal of Clinical Investigation. 130, 12, p. 6338-6353 16 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File