Research output per year
Research output per year
Personal profile
Curriculum vitae
The Biological Physics group led by Ilpo Vattulainen utilizes computational biophysics and scientific computing to promote health and understand biological processes, focusing on high-impact projects that are integrated with experimental research. The group develops new techniques for multi-scale simulations and data analysis (AI/ML). The research topics mainly deal with membrane receptors, lipids, protein function, viruses and signaling, with the aim of elucidating the mechanisms of diseases such as viral diseases, cancers and dry eye syndrome.
Fields of Science
- 114 Physical sciences
- 1182 Biochemistry, cell and molecular biology
- 116 Chemical sciences
- 221 Nano-technology
International and National Collaboration
Publications and projects within past five years.
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Assessing vitamin E acetate as a proxy for E-cigarette additives in a realistic pulmonary surfactant model
Korolainen, H., Olżyńska, A., Pajerski, W., Chytrosz-Wrobel, P., Vattulainen, I., Kulig, W. & Cwiklik, L., Dec 2024, In: Scientific Reports. 14, 1, 11 p., 23805.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Disulfide bridge-dependent dimerization triggers FGF2 membrane translocation into the extracellular space
Lolicato, F., Steringer, J. P., Saleppico, R., Beyer, D., Fernandez-Sobaberas, J., Unger, S., Klein, S., Riegerová, P., Wegehingel, S., Müller, H.-M., Schmitt, X. J., Kaptan, S., Freund, C., Hof, M., Šachl, R., Chlanda, P., Vattulainen, I. & Nickel, W., 22 Jan 2024, In: eLife. 12, 42 p., RP88579.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Exposure to Aldehyde Cherry e-Liquid Flavoring and Its Vaping Byproduct Disrupt Pulmonary Surfactant Biophysical Function
Martin, A., Tempra, C., Yu, Y., Liekkinen, J., Thakker, R., Lee, H., Moreno, B. D. S., Vattulainen, I., Rossios, C., Javanainen, M. & de la Serna, J. B., 8 Jan 2024, In: Environmental Science & Technology. 58, 3, p. 1495-1508 14 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Martini 3 OliGo̅mers: A Scalable Approach for Multimers and Fibrils in GROMACS
Korshunova, K., Kiuru, J., Liekkinen, J., Enkavi, G., Vattulainen, I. & Bruininks, B. M. H., 27 Aug 2024, In: Journal of Chemical Theory and Computation. 20, 17, p. 7635–7645 11 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Membrane remodeling by FAM92A1 during brain development regulates neuronal morphology, synaptic function, and cognition
Wang, L., Yang, Z., Fudo, S., Anthony Raj, X. P., Yan, Z., Vihinen, H., Chen, Y., Zhao, Y., He, X., Bu, Q., Li, H., Zhao, Y., Jiang, L., Qin, F., Dai, Y., Zhang, N., Qin, M., Kuang, W., Zhao, Y. & Jokitalo, E. & 4 others, , 2024, In: Nature Communications. 15, 1, 30 p., 6209.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
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Jusélius/Vattulainen 2024-27
Vattulainen, I. T. (Project manager), Haapanen, O. (Participant), Hosseinidolama, M. (Participant), Kiuru, J. O. T. (Participant), Nieminen, V. M. E. (Participant), Roschier, M. (Participant) & Torniainen, M. P. (Participant)
Sigrid Juséliuksen Säätiö @003701165704@
01/05/2024 → 30/04/2026
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
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BarrierFor: Biological Barrier Mechanics and Disease: From molecular-scale to tissue-level understanding of signal integration and forces (BarrierForce)
Vattulainen, I. T. (Project manager), Hägg, V. M. L. (Participant), Korshunova, K. (Participant), Martikainen, A. O. J. (Participant), Paajanen, S. E. (Participant), Soennichsen, C. H. (Participant), Torniainen, M. P. (Participant) & Vihuri, S. T. K. (Participant)
01/01/2024 → 31/12/2026
Project: Research Council of Finland: Centre of Exellence
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Lundbeck-Castrén
Castrén, E. (Project manager), Lauri, S. (Project manager), Vattulainen, I. T. (Project manager), Brunello, C. (Participant), Didio, G. (Participant), Kaptan, S. S. (Participant), Kaurinkoski, K. V. S. (Participant), Keskinen, R. (Participant), Kunnari, A.-J. A. (Participant), Le Joncour, V. (Participant), Ojanen, S. (Participant), Shteinikov, V. (Participant) & Srinivasan, R. (Participant)
Tuntematon rahoittaja, Lundbeckfonden Lundbeck Foundation
01/04/2023 → 31/03/2028
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
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MOLiNTEL: Molecular Basis of Intelligence
Kaptan, S. S. (Principal Investigator), Eurasto, F. (Participant), Paajanen, S. E. (Participant), Pirnes, S. J. (Participant) & Vattulainen, I. T. (Project manager)
01/01/2021 → 31/12/2023
Project: University of Helsinki Three-Year Research Project
Activities
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Membrane dynamics with nanoparticles: Roles of electrostatics, glycans, and crowding
Vattulainen, I. T. (Speaker)
12 Jun 2017 → 16 Jun 2017Activity: Talk or presentation types › Oral presentation
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Lipids controlling membrane receptor conformation and activation: Perspective through molecular simulations
Vattulainen, I. T. (Speaker)
20 Sept 2017 → 22 Sept 2017Activity: Talk or presentation types › Oral presentation
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Lipids and glycans govern membrane receptor conformation and accessibility – How do they do it?
Vattulainen, I. T. (Speaker)
29 May 2017 → 30 May 2017Activity: Talk or presentation types › Oral presentation
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How membrane proteins sense cholesterol
Vattulainen, I. T. (Speaker)
23 Jan 2017 → 27 Jan 2017Activity: Talk or presentation types › Oral presentation
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Introduction to MD methods
Vattulainen, I. T. (Speaker)
2 Jul 2017 → 9 Jul 2017Activity: Talk or presentation types › Oral presentation