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Personal profile

Description of research and teaching

Dr. Kaprio has worked in epidemiology, in particular genetic epidemiology. His central interests have been in the study of adult chronic disease and the development of their behavioral risk factors with a focus on addictions and metabolic conditions. In particular genetic and environmental factors affecting smoking, alcohol use, physical inactivity, sleep and obesity have been studied using twin, family and molecular genetic approaches. 

He has worked with the Finnish Cohort studies since 1976, and has been responsible for a steady expansion of the included cohorts and very extensive phenotyping through repeated questionnaire and interview surveys, biosample collections and record-linkage to national medical registries. He is an internationally recognized expert in epidemiology and twin studies with over 1100 original scientific publications. He has been cited some 60,000 times (WoS 6/2019) and has a H-index of 114 (6/2019). 

He has had continuous NIH funding for the past 25 years and was Director of the Academy of Finland Centre of Excellence in Complex Disease Genetics (2007-2011). He has received several international science awards and he has been President of the International Society for Twin Studies,  President of the Society for Research on Nicotine and Tobacco European chapter, and President of the Behavior Genetics Association. He has supervised  51 PhD students and received the Maud Kuistila award for excellence in doctoral training. He has received two honorary doctorates, one from the University of Southern Denmark, and the other from the University of Jyväskylä in 2019.  He held an Academy of Finland professorship for 2013-2017.

Education information

Jaakko Kaprio, M.D., Ph.D. is Professor of Genetic Epidemiology at the University of Helsinki, Finland and Research Professor in Behavioral Genetics at the National Institute for Health and Welfare, Helsinki. He graduated from medical school (University of Helsinki) in 1976, and defended his PhD in Epidemiology in 1984. He has trained abroad at the University of Southern California, Indiana University and University of Michigan in 1987-1989.

External positions

Johtoryhmän jäsen, Biokeskus Suomi - Biocenter Finland

1 Jan 2016 → …

Tieteelliseettisen ryhmän jäsen, Helsingin Biopankki

Keywords

  • 314 Health sciences
  • genetic epidemiology
  • epidemiology
  • 3142 Public health care science, environmental and occupational health
  • twin study
  • 3112 Neurosciences
  • addiction
  • tobacco dependence

International and National Collaboration Publications and projects within past five years.

Publications 1976 2019

A population-specific HTR2B stop codon predisposes to severe impulsivity

Bevilacqua, L., Doly, S., Kaprio, J., Yuan, Q., Tikkanen, R., Paunio, T., Zhou, Z., Wedenoja, J., Maroteaux, L., Diaz, S., Belmer, A., Hodgkinson, C. A., Dell'Osso, L., Suvisaari, J., Coccaro, E., Rose, R. J., Peltonen, L., Virkkunen, M. & Goldman, D., 2010, In : Nature. 468, 7327 , p. 1061-U460 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Genome-wide meta-analyses identify multiple loci associated with smoking behavior

Furberg, H., Kim, Y., Dackor, J., Boerwinkle, E., Franceschini, N., Ardissino, D., Bernardinelli, L., Mannucci, P. M., Mauri, F., Merlini, P. A., Absher, D., Assimes, T. L., Fortmann, S. P., Iribarren, C., Knowles, J. W., Quertermous, T., Ferrucci, L., Tanaka, T., Bis, J. C., Furberg, C. D. & 96 othersHaritunians, T., McKnight, B., Psaty, B. M., Taylor, K. D., Thacker, E. L., Almgren, P., Groop, L., Ladenvall, C., Boehnke, M., Jackson, A. U., Mohlke, K. L., Stringham, H. M., Tuomilehto, J., Benjamin, E. J., Hwang, S-J., Levy, D., Preis, S. R., Vasan, R. S., Duan, J., Gejman, P. V., Levinson, D. F., Sanders, A. R., Shi, J., Lips, E. H., Mckay, J. D., Agudo, A., Barzan, L., Bencko, V., Benhamou, S., Castellsague, X., Canova, C., Conway, D. I., Fabianova, E., Foretova, L., Janout, V., Healy, C. M., Holcatova, I., Kjaerheim, K., Lagiou, P., Lissowska, J., Lowry, R., Macfarlane, T. V., Mates, D., Richiardi, L., Rudnai, P., Szeszenia-Dabrowska, N., Zaridze, D., Znaor, A., Lathrop, M., Brennan, P., Bandinelli, S., Frayling, T. M., Guralnik, J. M., Milaneschi, Y., Perry, J. R. B., Altshuler, D., Elosua, R., Kathiresan, S., Lucas, G., Melander, O., O'Donnell, C. J., Salomaa, V., Schwartz, S. M., Voight, B. F., Penninx, B. W., Smit, J. H., Vogelzangs, N., Boomsma, D. I., de Geus, E. J. C., Vink, J. M., Willemsen, G., Chanock, S. J., Gu, F., Hankinson, S. E., Hunter, D. J., Hofman, A., Tiemeier, H., Uitterlinden, A. G., van Duijn, C. M., Walter, S., Chasman, D. I., Everett, B. M., Pare, G., Ridker, P. M., Li, M. D., Maes, H. H., Audrain-McGovern, J., Posthuma, D., Thornton, L. M., Lerman, C., Kaprio, J., Rose, J. E., Ioannidis, J. P. A., Kraft, P., Lin, D-Y. & Sullivan, P. F., 2010, In : Nature Genetics. 42, p. 441-447 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

Thorgeirsson, T. E., Gudbjartsson, D. F., Surakka, I. L., Vink, J. M., Amin, N., Geller, F., Sulem, P., Rafnar, T., Esko, T., Walter, S., Gieger, C., Rawal, R., Mangino, M., Prokopenko, I., Maegi, R., Keskitalo, K., Gudjonsdottir, I. H., Gretarsdottir, S., Stefansson, H., Thompson, J. R. & 31 othersAulchenko, Y. S., Nelis, M., Aben, K. K., den Heijer, M., Dirksen, A., Ashraf, H., Soranzo, N., Valdes, A. M., Steves, C., Uitterlinden, A. G., Hofman, A., Toenjes, A., Kovacs, P., Hottenga, J. J., Willemsen, G., Vogelzangs, N., Doering, A., Dahmen, N., Nitz, B., Pergadia, M. L., Saez, B., De Diego, V., Lezcano, V., Garcia-Prats, M. D., Ripatti, S. O., Perola, M., Kettunen, J., Shen, H-Y., Kaprio, J., Palotie, L. & ENGAGE Consortium, 2010, In : Nature Genetics. 42, p. 448-453 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Personality Traits and Cancer Risk and Survival Based on Finnish and Swedish Registry Data

Nakaya, N., Bidstrup, P. E., Saito-Nakaya, K., Frederiksen, K., Koskenvuo, M., Pukkala, E., Kaprio, J., Floderus, B., Uchitomi, Y. & Johansen, C., 2010, In : American Journal of Epidemiology. 172, 4, p. 377-385 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Heritability and Mortality Risk of Insomnia-Related Symptoms: A Genetic Epidemiologic Study in a Population-Based Twin Cohort

Hublin, C., Partinen, M., Koskenvuo, M. & Kaprio, J., 2011, In : Sleep. 34, 7, p. 957-964 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Projects 1974 2020

Activities 1990 2018

Oxford Research Encyclopedia of Psychology (Journal)

Jaakko Arthur Kaprio (Reviewer)
2018

Activity: Publication peer-review and editorial work typesPeer review of manuscripts

Serving as a grant reviewer for The Netherlands Organisation for Health Research and Development

Jaakko Arthur Kaprio (Participant)
2018

Activity: Other activity typesTypes for other activities - Other

Kirstie O'Hare

Tellervo Korhonen (Host), Jaakko Arthur Kaprio (Host)
16 Apr 201825 May 2018

Activity: Hosting a visitor typesAcademic visit at UH

University of Helsinki (Organisational unit)

Jaakko Arthur Kaprio (Expert member)
20182019

Activity: Membership typesMembership or other role in national/international committee, council, board

Kirsti O'Hare

Jaakko Arthur Kaprio (Host)
14 Apr 201825 May 2018

Activity: Hosting a visitor typesAcademic visit at UH

Press / Media

Interview fo YLE Akuutti: Kaksostutkimus ja syöpätyyppien perinnöllisyys

Jaakko Kaprio

11/03/2017

1 item of media coverage

Press/Media: Press / Media

Interview for Helsingin Sanomat: Kaksoset paljastavat erot

Jaakko Kaprio

19/08/2016

1 item of media coverage

Press/Media: Press / Media

Interview for Kodin Pellervo magazine: Syöpätyyppien perinnöllinen riski

Jaakko Kaprio

12/02/2016

1 item of media coverage

Press/Media: Press / Media

Interview for Karjalainen newspaper

Jaakko Kaprio

12/02/2016

1 item of media coverage

Press/Media: Press / Media

Interview for Liikunta & Tiede: Kaksostutkija kaksoisroolissa

Jaakko Kaprio

12/01/2016

1 item of media coverage

Press/Media: Press / Media