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  • PL 20 (Tukholmankatu 8)

    00014

    Finland

19982019
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Personal profile

Keywords

  • 1182 Biochemistry, cell and molecular biology

International and National Collaboration Publications and projects within past five years.

Publications 1998 2019

Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer

Tang, J., Gautam, P., Gupta, A., He, L., Timonen, S., Akimov, Y., Wang, W., Szwajda, A., Jaiswal, A., Turei, D., Yadav, B., Kankainen, M., Saarela, J., Saez-Rodriguez, J., Wennerberg, K. & Aittokallio, T., 2019, In : npj Systems Biology and Applications. 5, 1

Research output: Contribution to journalArticleScientificpeer-review

Methods for High-throughput Drug Combination Screening and Synergy Scoring

He, L., Kulesskiy, E., Saarela, J. S., Turunen, L. L., Wennerberg, J. K., Aittokallio, T. A. & Tang, J., 2018, Cancer Systems Biology. von Stechow, L. (ed.). New York: Humana Press, p. 351-398 48 p. (Methods in molecular biology; no. 1711).

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins

Bulanova, D., Ianevski, A., Bugai, A., Akimov, Y., Kuivanen, S., Paavilainen, H., Kakkola, L., Nandania, J., Turunen, L., Ohman, T., Ala-Hongisto, H., Pesonen, H. M., Kuisma, M. S., Honkimaa, A., Walton, E. L., Oksenych, V., Lorey, M. B., Guschin, D., Shim, J., Kim, J. & 23 othersThan, T. T., Chang, S. Y., Hukkanen, V., Kulesskiy, E., Marjomaki, V. S., Julkunen, I., Nyman, T. A., Matikainen, S., Saarela, J. S., Sane, F., Hober, D., Gabriel, G., De Brabander, J. K., Martikainen, M., Windisch, M. P., Min, J-Y., Bruzzone, R., Aittokallio, T., Vaha-Koskela, M., Vapalahti, O., Pulk, A., Velagapudi, V. & Kainov, D. E., Oct 2017, In : Viruses. 9, 10, 15 p., 271.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Dasatinib Reversibly Disrupts Endothelial Vascular Integrity by Increasing Non-Muscle Myosin II Contractility in a ROCK-Dependent Manner

Kreutzman, A., Colom-Fernandez, B., Marcos Jimenez, A., Ilander, M., Cuesta-Mateos, C., Perez-Garcia, Y., Delgado Arevalo, C., Bruck, O., Hakanen, H., Saarela, J., Ortega-Carrion, A., de Rosendo, A., Juanes-Garcia, A., Luis Steegmann, J., Mustjoki, S., Vicente-Manzanares, M. & Munoz-Calleja, C., 1 Nov 2017, In : Clinical Cancer Research. 23, 21, p. 6697-6707 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

HOX gene expression predicts response to BCL-2 inhibition in acute myeloid leukemia

Kontro, M., Kumar, A., Majumder, M. M., Eldfors, S., Parsons, A., Pemovska, T., Saarela, J. S., Yadav, B., Malani, D. R., Fløisand, Y., Höglund, M., Remes, K., Gjertsen, B-T., Kallioniemi, O-P., Wennerberg, J. K., Heckman, C. A. & Porkka, K. V. K., 2017, In : Leukemia. 31, 2, p. 301-309 9 p.

Research output: Contribution to journalArticleScientificpeer-review

File

Projects

Prizes

The 2017 SLAS Technology Ten

Evgeny Kulesskiy (Recipient), Jani Saarela (Recipient), Laura Turunen (Recipient) & Krister Wennerberg (Recipient), 1 Feb 2017

Prize: Prizes and awards

Activities 2010 2016

Workshop: Early Stage Drug Discovery in Finland and in Oulu

Jani Saarela (Speaker: Presenter)
13 Sep 2016

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

Screening at the High Throughput Biomedicine Unit

Jani Saarela (Speaker)
13 Sep 201614 Sep 2016

Activity: Talk or presentation typesOral presentation

RNAi Screening and Cell Based Assay Program at FIMM: The Impact of Acoustic Dispensing to Improve Process Flows

Jani Saarela (Speaker)
28 Sep 201629 Sep 2016

Activity: Talk or presentation typesOral presentation

Nordic Chemical Biology Meeting

Jani Saarela (Attendee)
5 May 20156 May 2015

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

Nordic Collaboration in Clinical Research -meeting

Jani Saarela (Attendee)
22 Apr 201523 Apr 2015

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars