Research Output per year
Personal profile
Keywords
- 1182 Biochemistry, cell and molecular biology
International and National Collaboration
Publications and projects within past five years.
Publications 1998 2019
Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer
Tang, J., Gautam, P., Gupta, A., He, L., Timonen, S., Akimov, Y., Wang, W., Szwajda, A., Jaiswal, A., Turei, D., Yadav, B., Kankainen, M., Saarela, J., Saez-Rodriguez, J., Wennerberg, K. & Aittokallio, T., 2019, In : npj Systems Biology and Applications. 5, 1Research output: Contribution to journal › Article › Scientific › peer-review
Methods for High-throughput Drug Combination Screening and Synergy Scoring
He, L., Kulesskiy, E., Saarela, J. S., Turunen, L. L., Wennerberg, J. K., Aittokallio, T. A. & Tang, J., 2018, Cancer Systems Biology. von Stechow, L. (ed.). New York: Humana Press, p. 351-398 48 p. (Methods in molecular biology; no. 1711).Research output: Chapter in Book/Report/Conference proceeding › Chapter › Scientific › peer-review
Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins
Bulanova, D., Ianevski, A., Bugai, A., Akimov, Y., Kuivanen, S., Paavilainen, H., Kakkola, L., Nandania, J., Turunen, L., Ohman, T., Ala-Hongisto, H., Pesonen, H. M., Kuisma, M. S., Honkimaa, A., Walton, E. L., Oksenych, V., Lorey, M. B., Guschin, D., Shim, J., Kim, J. & 23 others, Oct 2017, In : Viruses. 9, 10, 15 p., 271.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access
File
Dasatinib Reversibly Disrupts Endothelial Vascular Integrity by Increasing Non-Muscle Myosin II Contractility in a ROCK-Dependent Manner
Kreutzman, A., Colom-Fernandez, B., Marcos Jimenez, A., Ilander, M., Cuesta-Mateos, C., Perez-Garcia, Y., Delgado Arevalo, C., Bruck, O., Hakanen, H., Saarela, J., Ortega-Carrion, A., de Rosendo, A., Juanes-Garcia, A., Luis Steegmann, J., Mustjoki, S., Vicente-Manzanares, M. & Munoz-Calleja, C., 1 Nov 2017, In : Clinical Cancer Research. 23, 21, p. 6697-6707 11 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access
HOX gene expression predicts response to BCL-2 inhibition in acute myeloid leukemia
Kontro, M., Kumar, A., Majumder, M. M., Eldfors, S., Parsons, A., Pemovska, T., Saarela, J. S., Yadav, B., Malani, D. R., Fløisand, Y., Höglund, M., Remes, K., Gjertsen, B-T., Kallioniemi, O-P., Wennerberg, J. K., Heckman, C. A. & Porkka, K. V. K., 2017, In : Leukemia. 31, 2, p. 301-309 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
File
Projects
Regulation of polysialic acid expression
Pajunen, M., Anderson, H., Lehti, T., Skog, M., Schachner, M., Kallioniemi, O., Saarela, J. & Finne, J.
Project: Research project
Prizes
The 2017 SLAS Technology Ten
Evgeny Kulesskiy (Recipient), Jani Saarela (Recipient), Laura Turunen (Recipient) & Krister Wennerberg (Recipient), 1 Feb 2017
Prize: Prizes and awards
Activities 2010 2016
Workshop: Early Stage Drug Discovery in Finland and in Oulu
Jani Saarela (Speaker: Presenter)13 Sep 2016
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Screening at the High Throughput Biomedicine Unit
Jani Saarela (Speaker)13 Sep 2016 → 14 Sep 2016
Activity: Talk or presentation types › Oral presentation
RNAi Screening and Cell Based Assay Program at FIMM: The Impact of Acoustic Dispensing to Improve Process Flows
Jani Saarela (Speaker)28 Sep 2016 → 29 Sep 2016
Activity: Talk or presentation types › Oral presentation
Nordic Chemical Biology Meeting
Jani Saarela (Attendee)5 May 2015 → 6 May 2015
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Nordic Collaboration in Clinical Research -meeting
Jani Saarela (Attendee)22 Apr 2015 → 23 Apr 2015
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars