20042018
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Publications 2004 2018

  • 18 Article
  • 1 Meeting Abstract
  • 1 Doctoral Thesis
  • 1 Master's thesis
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Article
2018

Extracellular Lipids Accumulate in Human Carotid Arteries as Distinct Three-Dimensional Structures and Have Proinflammatory Properties

Lehti, S., Nguyen, S. D., Belevich, I., Vihinen, H., Heikkilä, H. M., Soliymani, R., Käkelä, R., Saksi, J., Jauhiainen, M., Grabowski, G. A., Kummu, O., Hörkkö, S., Baumann, M., Lindsberg, P. J., Jokitalo, E., Kovanen, P. T. & Öörni, K., Feb 2018, In : The American Journal of Pathology. 188, 2, p. 525-538 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Morphology and histology of silent and symptom-causing atherosclerotic carotid plaques - Rationale and design of the Helsinki Carotid Endarterectomy Study 2 (the HeCES2)

Nuotio, K., Ijäs, P., Heikkilä, H. M., Koskinen, S. M., Saksi, J., Vikatmaa, P., Sorto, P., Mäkitie, L., Eriksson, H., Kasari, S., Silvennoinen, H., Valanne, L., Mäyränpää, M. I., Kovanen, P. T., Soinne, L. & Lindsberg, P. J., 2018, In : Annals of Medicine. 50, 6, p. 501-510 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2017

Haptoglobin Hp2 Variant Promotes Premature Cardiovascular Death in Stroke Survivors

Ijas, P., Melkas, S., Saksi, J., Jula, A., Jauhiainen, M., Oksala, N., Pohjasvaara, T., Kaste, M., Karhunen, P. J., Lindsberg, P. & Erkinjuntti, T., Jun 2017, In : Stroke. 48, 6, p. 1463-+ 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
2015

Life-threatening coronary disease is prevalent in patients with stenosing carotid artery disease

Nuotio, K., Soinne, L., Hänninen, H., Saksi, J., Tuimala, J., Jula, A., Kovanen, P. T., Kaste, M., Ijas, P. & Lindsberg, P. J., Dec 2015, In : International Journal of Stroke. 10, 8, p. 1217-1223 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Workflow for automated quantification of cerebromicrovascular gelatinase activity

Mattila, O. S., Rantanen, V., Saksi, J., Strbian, D., Pikkarainen, T., Hautaniemi, S. & Lindsberg, P. J., Jan 2015, In : Microvascular Research. 97, p. 19-24 6 p.

Research output: Contribution to journalArticleScientificpeer-review

2014

Evolution of intracerebral hemorrhage after intravenous tPA: reversal of harmful effects with mast cell stabilization

Marinkovic, I., Mattila, O. S., Strbian, D., Meretoja, A., Shekhar, S., Saksi, J., Abo Ramadan, U., Rantanen, V., Lindsberg, P. J. & Tatlisumak, T., Jan 2014, In : Journal of Cerebral Blood Flow and Metabolism. 34, 1, p. 176-181 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Low-Expression Variant of Fatty Acid-Binding Protein 4 Favors Reduced Manifestations of Atherosclerotic Disease and Increased Plaque Stability

Saksi, J., Ijas, P., Mayranpaa, M. I., Nuotio, K., Isoviita, P. M., Tuimala, J., Lehtonen-Smeds, E., Kaste, M., Jula, A., Nieminen, M. S., Lokki, M-L., Perola, M., Havulinna, A. S., Salomaa, V., Kettunen, J., Jauhiainen, M., Kovanen, P. T. & Lindsberg, P. J., Oct 2014, In : Circulation. Cardiovascular genetics. 7, 5, p. 588-598 11 p.

Research output: Contribution to journalArticleScientificpeer-review

2013

Haptoglobin 2 allele associates with unstable carotid plaque and major cardiovascular events

Ijäs, P., Saksi, J., Soinne, L., Tuimala, J., Jauhiainen, M., Jula, A., Kahonen, M., Kesaniemi, Y. A., Kovanen, P. T., Kaste, M. & Lindsberg, P. J., Oct 2013, In : Atherosclerosis. 230, 2, p. 228-234 7 p.

Research output: Contribution to journalArticleScientificpeer-review

2011

Cerebral Mast Cells Mediate Blood-Brain Barrier Disruption in Acute Experimental Ischemic Stroke Through Perivascular Gelatinase Activation

Mattila, O. S., Strbian, D., Saksi, J., Pikkarainen, T. O., Rantanen, V., Tatlisumak, T. & Lindsberg, P. J., 2011, In : Stroke. 42, 12, p. 3600-U410 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Gene expression differences between stroke-associated and asymptomatic carotid plaques

Saksi, J., Ijäs, P., Nuotio, K., Sonninen, R., Soinne, L., Salonen, O., Saimanen, E., Tuimala, J., Lehtonen-Smeds, E. M., Kaste, M., Kovanen, P. T. & Lindsberg, P. J., 2011, In : Journal of Molecular Medicine. 89, 10, p. 1015-1026 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Is coproporphyrin III a copper-acquisition compound in Paracoccus denitrificans?

Anttila, J., Heinonen, P., Nenonen, T., Pino, A., Iwai, H., Kauppi, E., Soliymani, R., Baumann, M., Saksi, J., Suni, N. & Haltia, T., 2011, In : Biochimica et Biophysica Acta. Bioenergetics. 1807, 3, p. 311-318 8 p.

Research output: Contribution to journalArticleScientificpeer-review

2010

An imbalance between CD36 and ABCA1 protein expression favors lipid accumulation in stroke-prone ulcerated carotid plaques

Isoviita, P., Nuotio, K., Saksi, J., Turunen, R., Ijäs, P., Pitkäniemi, J. M., Soinne, L. S., Kaste, M., Kovanen, P. T. & Lindsberg, P., 2010, In : Stroke. 41, 2, p. 389-393 5 p.

Research output: Contribution to journalArticleScientificpeer-review

2009

Neuronal caspase-3 and PARP-1 correlate differentially with apoptosis and necrosis in ischemic human stroke

Sairanen, T., Szepesi, R., Karjalainen-Lindsberg, M-L., Saksi, J., Paetau, A. & Lindsberg, P. J., 2009, In : Acta Neuropathologica. 118, 4, p. 541-552 12 p.

Research output: Contribution to journalArticleScientificpeer-review

2007

Adipophilin expression is increased in symptomatic carotid atherosclerosis: correlation with red blood cells and cholesterol crystals

Nuotio, K., Isoviita, P., Saksi, J., Ijäs, P., Pitkäniemi, J., Sonninen, R., Soinne, L., Saimanen, E., Salonen, O., Kovanen, P. T., Kaste, M. & Lindsberg, P. J., 2007, In : Stroke. 38, 6, p. 1791-1798 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Endothelial apoptosis does not determine symptom status in carotid artery disease

Nuotio, K., Mäyränpää, M., Saksi, J., Ijäs, P., Sairanen, T., Carpen, O., Soinne, L., Saimanen, E., Salonen, O., Lepäntalo, M., Kovanen, P. T., Kaste, M. & Lindsberg, P. J., 2007, In : Cerebrovascular Diseases. 23, 1, p. 27-34 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Microarray analysis reveals overexpression of CD163 and HO-1 in symptomatic carotid plaques

Ijäs, P., Nuotio, K., Saksi, J., Soinne, L., Saimanen, E., Karjalainen-Lindsberg, M-L., Salonen, O., Sarna, S., Tuimala, J., Kovanen, P. T., Kaste, M. & Lindsberg, P. J., 2007, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 27, 1, p. 154-160 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Mikroverenvuodot ja CD163-HO1-signalointi oireilevassa kaukavaltimon ateroskleroosissa: [Arterioscler Thromb Vasc Biol in press]

Ijäs, P., Nuotio, K., Saksi, J., Soinne, L., Saimanen, E., Karjalainen-Lindsberg, M-L., Salonen, O., Sarna, S., Tuimala, J., Kovanen, P. T., Kaste, M. & Lindsberg, P. J., 2007, In : Duodecim. 123, p. 141-142 2 p.

Research output: Contribution to journalArticleScientific

2004

Genes involved in iron/heme metabolism are upregulated in symptomatic carotid artery disease

Ijas, P., Nuotio, K., Saksi, J., Soinne, L., Saimanen, E., Salonen, O., Sarna, S., Carpen, O. M., Kovanen, P. T., Lassila, R., Kaste, M. & Lindsberg, P., 2004, In : Stroke. 35, p. 305-306 2 p.

Research output: Contribution to journalArticleScientificpeer-review