Research output per year
Research output per year
Personal profile
Fields of Science
- 3111 Biomedicine
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Drivers of clinical resistance to venetoclax and hypomethylating agents in acute myeloid leukemia and strategies for improving efficacy
Vänttinen, I., Saad, J., Ruokoranta, T., Kytölä, S., Qin, G., Tercan, B., Ettala, P., Partanen, A., Pyörälä, M., Rimpiläinen, J., Siitonen, T., Manninen, M., Valk, P. J. M., Huls, G., Thorsson, V., Heckman, C. A., Kontro, M. & Kuusanmäki, H., 11 Jan 2026, In: Hemasphere. 10, 1, 16 p., e70282.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
NAMPT haploinsufficiency is a therapeutic vulnerability to NAMPT inhibition in -7/-7q MDS
Ikonen, N., Ruokoranta, T., Hyyppä, S., Sinervuori, E., Miettinen, J. J., Saad, J., Vähä-Koskela, M. & Heckman, C. A., 17 Jun 2026, In: Biomarker Research. 14, 1, 5 p., 62.Research output: Contribution to journal › Letter › Scientific
Open Access -
DEK::NUP214 acts as an XPO1-dependent transcriptional activator of essential leukemia genes
Kaya, F., Bewicke-Copley, F., Miettinen, J. J., Casado, P., Leddy, E., Deniz, Ö., Lavallée, V. P., Philippe, C., Zheng, J., Grebien, F., Khan, N., Krizsán, S., Saad, J., Nolin-Lapalme, A., Hébert, J., Lemieux, S., Audemard, E., Matthews, J., Grantham, M. & Di Bella, D. & 17 others, , 9 Apr 2025, In: Leukemia. 39, p. 1526-1531 6 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Ex vivo venetoclax sensitivity predicts clinical response in acute myeloid leukemia in the prospective VenEx trial
Kytölä, S., Vänttinen, I. M., Ruokoranta, T., Partanen, A., Holopainen, A., Saad, J., Kuusisto, M. E. L., Koskela, S., Räty, R., Itälä-Remes, M., Västrik, I., Suvela, M., Parsons, A. O., Porkka, K., Wennerberg, K., Heckman, C. A., Jalkanen, T., Huttunen, T., Ettala, P. & Rimpiläinen, J. & 4 others, , 23 Jan 2025, In: Blood. 145, 4, p. 409-421 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Predictors of response and rational combinations for the novel MCL-1 inhibitor MIK665 in acute myeloid leukemia
Saad, J., Newman, R., Khabusheva, E., Aakko, S., Durand, E., Tambe, M., Kuusanmäki, H., Parsons, A., Miettinen, J. J., Javarappa, K. K., Olgac, E. J., Ikonen, N., Kontro, M., Porkka, K., Maacke, H., Woo, J., Halilovic, E. & Heckman, C. A., 21 Sept 2025, In: Molecular oncology. 20 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
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AMLDT: A Prototype System for AML Digital Twins
Heckman, C. (Project manager), Gholizadeh, E. (Participant), Ianevski, F. (Participant), Kumari, R. (Participant), Newman, R. G. D. (Participant), Saad, J. (Participant), Srivastava, A. (Participant) & Tanoli, Z. (Participant)
Suomen Akatemia Projektilaskutus
01/01/2023 → 31/12/2027
Project: Research Council of Finland: Bilateral partnerships, joint calls
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iCAN - Digital precision cancer medicine for discoveries and improved treatments
Mäkelä, T. (Project manager), Adhikari, S. (Participant), Aldahdooh, J. M. F. (Participant), Ariotta, V. (Participant), Arjama, M. A. (Participant), Atarsaikhan, G. (Participant), Bao, J. (Participant), Barreiro, K. (Participant), Bhalke, M. S. (Participant), Bollepalli, S. (Participant), Brandt, J. A. J. (Participant), Chernenko, A. (Participant), Dashi, G. (Participant), Eloranta, K. (Participant), Eriksson, M. R. (Participant), Feodoroff, M. J. (Participant), Fey, E. (Participant), Gerber, L. J. (Participant), Grönholm, M. (Participant), Hannula, S. A. (Participant), Heistman, V. (Participant), Henriksson, M. E. J. (Participant), Hiitola, E. T. J. (Participant), Huttunen, A. T. (Participant), Hyyppä, S. P. P. (Participant), Högel-Starck, C. S. P. (Participant), Ianevski, A. (Participant), Ikonen, N. (Participant), Jansouz, S. (Participant), Jha, S. (Participant), Junquera Mencía, A. (Participant), Kalashnikov, I. (Participant), Kampanellou, E. (Participant), Karabayev, D. (Participant), Karhemo, P.-R. (Participant), Karling, T. S. (Participant), Kekkonen, J. (Participant), Kolikova, Y. (Participant), Krami Senhaji, O. (Participant), Kuijjer, M. (Participant), Kuisma-van der Linden, M. S. (Participant), Kumari, R. (Participant), Kuosmanen, A. (Participant), Kurki, V. (Participant), Kuusela, S. (Participant), Kücükel, H. (Participant), Langohr, L. (Participant), Lavikka, K. A. (Participant), Le Joncour, V. (Participant), Lehto, T.-P. (Participant), Leivonen, S.-K. (Participant), Liljeström, M. (Participant), Lindfors, I. S. (Participant), Lindgren, H. (Participant), Luck, T. J. (Participant), Lähdeniemi, I. A. K. (Participant), Maarala, A. I. (Participant), Maljanen, K. J. (Participant), Marchi, G. (Participant), Martikainen, E. M. (Participant), Meriranta, L. (Participant), Metsäranta, N. A. C. (Participant), Miihkinen, M. S. (Participant), Moradi, N. (Participant), Nader, K. M. (Participant), Nagaraj, A. (Participant), Nguyen, M. (Participant), Niemeyer, F. (Participant), Niemiec, I. (Participant), Nylén, M. M. (Participant), Palin, K. (Participant), Palva, A. (Participant), Parsons, A. O. (Participant), Peltonen, J. H. H. (Participant), Perez Villatoro, F. R. (Participant), Pietiäinen, V. (Participant), Pirinen, I. E. (Participant), Pirttikoski, A. A. (Participant), Pitko, I. M. (Participant), Polianskyte-Prause, Z. (Participant), Puhka, M. (Participant), Quintero, I. B. (Participant), Rachidi, S. E. (Participant), Rajalaakso, M. T. (Participant), Rodosthenous, R. (Participant), Saad, J. (Participant), Sanjaya, P. (Participant), Seppälä, T. T. (Participant), Seref Vujaklija, C. (Participant), Shah, S. (Participant), Sorri, S. P. (Participant), Suni, V. (Participant), Suutala, A. (Participant), Suvela, M. (Participant), Sysivirta, L. K. M. (Participant), Udayani, J. E. (Participant), Verkasalo, H. M. (Participant), Viiri, L. E. (Participant), Vilkkavaara Cancocak, Y. (Participant), Vähärautio, A. (Participant), Vänttinen, I. M. (Participant), Västrik, I. (Participant), Väänänen, J. (Participant), Wang, W. (Participant) & Zhang, X. (Participant)
Suomen Akatemia Projektilaskutus, Academy of Finland
01/09/2022 → 31/12/2026
Project: Research Council of Finland: Finnish Flagship Programme
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Heckman Jusélius 1/3 2023-24
Heckman, C. (Project manager), Ikonen, N. (Participant), Mendoza Ortiz, E. D. (Participant), Olgac, E. J. (Participant), Saad, J. (Participant), Tambe, M. (Participant) & Tsallos, D. (Participant)
Sigrid Juséliuksen Säätiö @003701165704@
01/05/2023 → 30/04/2026
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
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Caroline Heckman NIH subaward ISB
Heckman, C. (Project manager), Adhikari, S. (Participant), Kallio, S. J. (Participant), Kuusanmäki, H. (Participant), Miettinen, J. (Participant), Olgac, E. J. (Participant), Parsons, A. O. (Participant), Ruokoranta, T. (Participant), Saad, J. (Participant), Sergeev, P. (Participant) & Srivastava, A. (Participant)
National Institutes of Health (NIH) OFM
01/01/2023 → 31/12/2025
Project: Other funder
Activities
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iCAN retreat 2024
Kremneva, E. (Chair of organizing committee), Kolikova, Y. (Member of organizing committee), Laakkonen, P. (Member of organizing committee), Vanharanta, S. (Member of organizing committee), Varjosalo, M. (Member of organizing committee), Wahl, H. (Member of organizing committee), Sankkila-Forsström, S. S. (Member of organizing committee), Duàn, H. (Speaker: Presenter), Karhemo, P.-R. (Speaker: Presenter), Miihkinen, M. S. (Speaker: Presenter), Liljeström, M. (Member of organizing committee), Pietiäinen, V. (Speaker: Presenter), Ganesan, A. (Poster Presentation), Saad, J. (Poster Presentation), Holmström, S. (Poster Presentation), Brodkin, J. H. (Poster Presentation), Mendoza Ortiz, E. D. (Poster Presentation), Sundaresan, S. (Poster Presentation), Chiaro, J. (Poster Presentation), Giannoula, Y. (Poster Presentation), Portaankorva, A. M. (Speaker: Presenter), Mustjoki, S. (Speaker: Presenter), Mäkelä, T. (Speaker: Presenter), Atarsaikhan, G. (Poster Presentation), Filppu, P. (Poster Presentation), Russo, S. (Poster Presentation), Pikkusaari, S. K. (Poster Presentation), Ryzhenkov, A. (Poster Presentation), Newman, R. G. D. (Speaker: Presenter), Arffman, M. E. (Speaker: Presenter), Kumari, R. (Poster Presentation), Leppiniemi, S. A. (Poster Presentation), Sanjaya, P. (Poster Presentation), Feodoroff, M. J. (Poster Presentation), Karabayev, D. (Poster Presentation), Jäntti, J. M. (Poster Presentation), Wong Ramirez, J. R. C. (Poster Presentation), Kalander, K. O. (Poster Presentation), Bouhlal, J. O. V. (Speaker: Presenter), Kuusela, S. (Speaker: Presenter), Fey, E. (Speaker: Presenter), Krami Senhaji, O. (Poster Presentation), Moradi, N. (Poster Presentation), Polso, M. M. M. (Poster Presentation), Antignani, G. (Poster Presentation), Maljanen, K. J. (Poster Presentation), Langohr, L. (Poster Presentation), Anil, A. (Poster Presentation), Smolander, P. J. (Poster Presentation), Feodoroff, M. J. (Poster Presentation), Alsaed, B. (Poster Presentation), Mogollon Figueroa, I. (Poster Presentation), Ryzhenkov, A. (Poster Presentation) & Henriksson, M. E. J. (Poster Presentation)
3 Oct 2024Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Monosomy 7 or del(7q) as Sensitivity Biomarkers to NAMPT Inhibition in Acute Myeloid Leukemia
Saad, J. (Speaker)
6 Sept 2022Activity: Talk or presentation types › Oral presentation
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Monosomy 7 and del(7q) Cause Select Sensitivity to inhibitors of NAMPT in Acute Myeloid Leukemia
Saad, J. (Speaker)
11 Dec 2022Activity: Talk or presentation types › Oral presentation
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Queen’s University Belfast
Saad, J. (Visiting researcher)
14 Jun 2022 → 16 Jun 2022Activity: Visiting an external institution types › Academic visit to other institution
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60th American Society of Hematology (ASH) Annula Meeting and Exposition
Saad, J. (Attendee)
1 Dec 2018 → 4 Dec 2018Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars