Research output per year
Research output per year
Personal profile
Fields of Science
- 3111 Biomedicine
International and National Collaboration
Publications and projects within past five years.
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Patient-derived tumor explant models of tumor immune microenvironment reveal distinct and reproducible immunotherapy responses
Turpin, R., Peltonen, K., Rannikko, J. H., Liu, R., Lee, M. H., Mutka, M., Kovanen, P., Meretoja, T., Mattson, J., Järvinen, P., Mirtti, T., Boström, P., Koskivuo, I., Thotakura, A. K., Pouwels, J., Hollmén, M., Mustjoki, S. & Klefström, J. T., 2025, In: OncoImmunology. 14, 1, 12 p., 2466305.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Liprin-α1 contributes to oncogenic MAPK signaling by counteracting ERK activity
Pehkonen, H., Filippou, A., Väänänen, J., Lindfors, I., Vänttinen, M., Ianevski, P., Mäkelä, A., Munne, P., Klefström, J., Toppila-Salmi, S., Grenman, R., Hagström, J., Mäkitie, A. A., Karhemo, P.-R. & Monni, O., Mar 2024, In: Molecular oncology. 18, 3, p. 662-676 15 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Respiratory complex I regulates dendritic cell maturation in explant model of human tumor immune microenvironment
Turpin, R., Liu, R., Munne, P. M., Peura, A., Rannikko, J. H., Philips, G., Boeckx, B., Salmelin, N., Hurskainen, E., Suleymanova, I., Aung, J., Vuorinen, E. M., Lehtinen, L., Mutka, M., Kovanen, P. E., Niinikoski, L., Meretoja, T. J., Mattson, J., Mustjoki, S. & Saavalainen, P. & 5 others, , 2024, In: Journal for ImmunoTherapy of Cancer. 12, 4, 18 p., e008053.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Fibrin Stiffness Regulates Phenotypic Plasticity of Metastatic Breast Cancer Cells
Heilala, M., Lehtonen, A., Arasalo, O., Peura, A., Pokki, J., Ikkala, O., Nonappa, Klefström, J. & Munne, P. M., Dec 2023, In: Advanced Healthcare Materials. 12, 31, 17 p., 2301137.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Hepsin promotes breast tumor growth signaling via the TGFβ-EGFR axis
Belitskin, D., Munne, P., Pant, S. M., Anttila, J. M., Suleymanova, I., Belitskina, K., Kirchhofer, D., Janetka, J., Käsper, T., Jalil, S., Pouwels, J., Tervonen, T. A. & Klefström, J., 13 Nov 2023, In: Molecular oncology. 15 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
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SJS 4/27 KLEFSTRÖM
Klefström, J. (Project manager) & Devarajan, G. R. (Participant)
Sigrid Juséliuksen Säätiö @003701165704@
01/05/2024 → 30/04/2025
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
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Syöpäsäätiö 24-26 Klefström Juha
Klefström, J. (Project manager), Anttila, J. (Participant), Peltonen, M. J. (Participant), Peura, A. A. (Participant) & Räty, I. (Participant)
Syöpäsäätiö sr Cancerstiftelsen sr
01/01/2024 → 31/12/2026
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
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BF-ReCurE / KLEFSTRÖM JUHA
Klefström, J. (Project manager), Brummer, M. (Participant), Devarajan, G. R. (Participant), Munne, P. (Participant) & Välimäki, M. (Participant)
01/01/2023 → 31/08/2025
Project: Business Finland
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MYC GEENIMUUTOKSEEN PERUSTUVIEN YHDISTELMÄHOITOJEN KEHITTÄMINEN LEVINNEEN RINTASYÖVÄN HOITOON
Klefström, J. (Project manager), Hollmann, B. (Participant), Savelius, M. (Participant), Tervonen, T. (Participant) & Turpin, R. J. K. (Participant)
01/09/2022 → 31/08/2026
Project: Research Council of Finland: Academy Project
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RED CROSS 12/2024 KLEFSTRÖM JUHA
Klefström, J. (Project manager), Devarajan, G. R. (Participant), Lehto, P. I. (Participant) & Liu, R. (Participant)
Suomen Punainen Risti Länsi-Helsingin osasto
01/01/2023 → 31/12/2024
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
Prizes
Activities
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Karolinska Institutet (External organisation)
Klefström, J. (Assessment)
2011Activity: Membership types › Membership or other role in review committee
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Doctoral thesis supervision / Eskelinen
Klefström, J. (Supervisor)
2011 → …Activity: Examination types › Supervisor or co-supervisor of doctoral thesis
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Doctoral thesis supervision / Marques
Klefström, J. (Supervisor)
2011 → …Activity: Examination types › Supervisor or co-supervisor of doctoral thesis
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Thesis opponent / Groth-Pedersen
Klefström, J. (Opponent)
2010Activity: Examination types › Opponent of doctoral dissertation
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LentiGEMM (lentiviral technology for in vivo gene transfer) Emerging Technology Platform (External organisation)
Klefström, J. (Expert)
2010 → …Activity: Membership types › Other tasks of an expert in private sector
Press/Media
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Participation in TV program on the Goodwill Gala Concert
14/11/2009
1 Media contribution
Press/Media: Press / Media
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Participarion in interview for NordForsk Magasin
01/01/2008
1 Media contribution
Press/Media: Press / Media
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Equipment
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HelVi: Biomedicum Virus Core (LS-RIA/ GoEditStem)
Klefström, J. (Manager)
Faculty of MedicineFacility/equipment: Core Facility