Photo of Juha Klefström
  • PL 63 (Haartmaninkatu 8)

    00014

    Finland

1990 …2019
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Personal profile

Keywords

  • 3111 Biomedicine

International and National Collaboration Publications and projects within past five years.

Publications 1990 2019

Discovery of Selective Matriptase and Hepsin Serine Protease Inhibitors: Useful Chemical Tools for Cancer Cell Biology

Damalanka, V. C., Han, Z., Karmakar, P., O'Donoghue, A. J., La Greca, F., Kim, T., Pant, S. M., Helander, J., Klefström, J., Craik, C. S. & Janetka, J. W., 24 Jan 2019, In : Journal of Medicinal Chemistry. 62, 2, p. 480-490 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy

Haikala, H. M., Anttila, J. M., Marques, E., Raatikainen, T., Ilander, M., Hakanen, H., Ala-Hongisto, H., Savelius, M., Balboa, D., Von Eyss, B., Eskelinen, V., Munne, P., Nieminen, A. I., Otonkoski, T., Schüler, J., Laajala, T. D., Aittokallio, T., Sihto, H., Mattson, J., Heikkilä, P. & 7 othersLeidenius, M., Joensuu, H., Mustjoki, S., Kovanen, P., Eilers, M., Leverson, J. D. & Klefström, J., 6 Feb 2019, In : Nature Communications. 10, 17 p., 620.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Analyzing the Type II Transmembrane Serine Protease Hepsin-Dependent Basement Membrane Remodeling in 3D Cell Culture

Pant, S. M., Belitskin, D., Ala-Hongisto, H., Klefström, J. & Tervonen, T. A., 2018, PROTEASES AND CANCER: METHODS AND PROTOCOLS . Cal, S. & Obaya, A. J. (eds.). TOTOWA, NJ : Humana Press Inc., p. 169-178 10 p. (Methods in Molecular Biology ; vol. 1731).

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Design, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization Platform

Pant, S. M., Mukonoweshuro, A., Desai, B., Ramjee, M. K., Selway, C. N., Tarver, G. J., Wright, A. G., Birchall, K., Chapman, T. M., Tervonen, T. A. & Klefström, J., 24 May 2018, In : Journal of Medicinal Chemistry. 61, 10, p. 4335-4347 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Kuinka pitää syöpä hengissä?

Munne, P. M., Savelius, M., Juopperi, I., Räty, I. & Klefström, J., 2018, In : Duodecim. 134, 8, p. 784-792 9 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Projects 2011 2016

PREDECT

Verschuren, E., Kallioniemi, O., Klefström, J. T., Monni, O. M. & Kovanen, P. E.

01/02/201131/01/2016

Project: Research project

Prizes

EMBO long-term fellowship

Juha Tapio Klefström (Recipient), 1996

Prize: Prizes and awards

EMBO short-term fellowship

Juha Tapio Klefström (Recipient), 1996

Prize: Prizes and awards

UCSF postdoctoral grant

Juha Tapio Klefström (Recipient), 1999

Prize: Prizes and awards

Activities 2002 2011

Doctoral thesis supervision / Marques

Juha Klefström (Supervisor)
2011 → …

Activity: Examination typesSupervisor or co-supervisor of doctoral thesis

Karolinska Institutet (External organisation)

Juha Klefström (Assessment)
2011

Activity: Membership typesMembership or other role in review committee

Doctoral thesis supervision / Eskelinen

Juha Klefström (Supervisor)
2011 → …

Activity: Examination typesSupervisor or co-supervisor of doctoral thesis

Pre-examination of doctoral thesis / Laurila

Juha Klefström (Supervisor)
2010

Activity: Examination typesPre-examiner of doctoral thesis

LentiGEMM (lentiviral technology for in vivo gene transfer) Emerging Technology Platform (External organisation)

Juha Klefström (Expert)
2010 → …

Activity: Membership typesOther tasks of an expert in private sector

Press / Media

Participation in TV program on the Goodwill Gala Concert

Juha Tapio Klefström

14/11/2009

1 media contribution

Press/Media: Press / Media

Participation in interview for APU magazine

Juha Tapio Klefström

01/01/2009

1 media contribution

Press/Media: Press / Media

Participarion in interview for NordForsk Magasin

Juha Tapio Klefström

01/01/2008

1 media contribution

Press/Media: Press / Media

Participation in a journal interview

Juha Tapio Klefström

01/01/2007

1 media contribution

Press/Media: Press / Media

Participation in TV program / Yle Teema

Juha Tapio Klefström

25/07/2006

1 media contribution

Press/Media: Press / Media