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  • PL 56 (Viikinkaari 9)

    00014

    Finland

  • Viikinkaari 5, Biocenter 2

    00790 Helsinki

    Finland

1990 …2020

Research output per year

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Personal profile

Description of research and teaching

Our group is interested in how neuronal diversity is generated during embryonic development. In particular, we study the mechanisms of intercellular communication and gene regulation, which control neuronal differentiation in a distinct region of the vertebrate brain -  the midbrain.

The midbrain contains neurons, such as dopaminergic and GABAergic neurons, which control several aspects of behavior, are involved in psychiatric disease and are targets of medical treatments as well as drugs of abuse.  However, their molecular diversity and regulation of their development from neuroepithelial stem cells are poorly understood. We are addressing these questions using a combination of genetic and molecular approaches.

 

Fields of Science

  • 1184 Genetics, developmental biology, physiology
  • 3112 Neurosciences

International and National Collaboration Publications and projects within past five years.

Publications

Kainate receptors regulate development of glutamatergic synaptic circuitry in the rodent amygdala

Ryazantseva, M., Englund, J., Shintyapina, A., Huupponen, J., Shteinikov, V., Pitkänen, A., Partanen, J. M. & Lauri, S. E., 23 Mar 2020, In : eLife. 9, 25 p., e52798.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Crosstalk of Intercellular Signaling Pathways in the Generation of Midbrain Dopaminergic Neurons In Vivo and from Stem Cells

Brodski, C., Blaess, S., Partanen, J. & Prakash, N., 15 Jan 2019, In : Journal of Developmental Biology. 7, 1, 34 p., 3.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
File

A complex genomic locus drives mtDNA replicase POLG expression to its disease-related nervous system regions

Nikkanen, J., Landoni, J. C., Balboa, D., Haugas, M., Partanen, J., Paetau, A., Isohanni, P., Brilhante, V. & Suomalainen, A., Jan 2018, In : EMBO molecular medicine. 10, 1, p. 13-21 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetes

Balboa, D., Saarimäki-Vire, J., Borshagovski, D., Survila, M., Lindholm, P., Galli, E., Eurola, S., Ustinov, J., Grym, H., Huopio, H., Partanen, J., Wartiovaara, K. & Otonkoski, T., 9 Nov 2018, In : eLife. 7, 35 p., 38519.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Dusp16 Deficiency Causes Congenital Obstructive Hydrocephalus and Brain Overgrowth by Expansion of the Neural Progenitor Pool

Zega, K., Jovanovic, V. M., Vitic, Z., Niedzielska, M., Knaapi, L., Jukic, M. M., Partanen, J., Friedel, R. F., Lang, R. & Brodski, C., 9 Nov 2017, In : Frontiers in Molecular Neuroscience. 10, 15 p., 372.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Prizes

Medix price 2008

Juha Partanen (Recipient), 2008

Prize: Prizes and awards

Medix prize 2004

Juha Partanen (Recipient), 2004

Prize: Prizes and awards

Activities

Examination of doctoral dissertation Jokinen

Juha Partanen (Pre-examiner)
2015

Activity: Examination typesPre-examiner of doctoral thesis

Examination of doctoral dissertation Zarkada

Juha Partanen (Pre-examiner)
2014

Activity: Examination typesPre-examiner of doctoral thesis

Examination of doctoral dissertation Hakanen

Juha Partanen (Pre-examiner)
2014

Activity: Examination typesPre-examiner of doctoral thesis

Examination of doctoral dissertation Zheng

Juha Partanen (Pre-examiner)
2013

Activity: Examination typesPre-examiner of doctoral thesis

Suomen kehitysbiologian seura (External organisation)

Juha Partanen (Chair)
20132015

Activity: Membership typesMembership or other role of body in private company/organisation