1990 …2018
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Personal profile

Description of research and teaching

Our group is interested in how neuronal diversity is generated during embryonic development. In particular, we study the mechanisms of intercellular communication and gene regulation, which control neuronal differentiation in a distinct region of the vertebrate brain -  the midbrain.

The midbrain contains neurons, such as dopaminergic and GABAergic neurons, which control several aspects of behavior, are involved in psychiatric disease and are targets of medical treatments as well as drugs of abuse.  However, their molecular diversity and regulation of their development from neuroepithelial stem cells are poorly understood. We are addressing these questions using a combination of genetic and molecular approaches.

 

Keywords

  • 1184 Genetics, developmental biology, physiology
  • 3112 Neurosciences

International and National Collaboration Publications and projects within past five years.

Publications 1990 2018

A complex genomic locus drives mtDNA replicase POLG expression to its disease-related nervous system regions

Nikkanen, J., Landoni, J. C., Balboa, D., Haugas, M., Partanen, J., Paetau, A., Isohanni, P., Brilhante, V. & Suomalainen, A., Jan 2018, In : EMBO molecular medicine. 10, 1, p. 13-21 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetes

Balboa, D., Saarimäki-Vire, J., Borshagovski, D., Survila, M., Lindholm, P., Galli, E., Eurola, S., Ustinov, J., Grym, H., Huopio, H., Partanen, J., Wartiovaara, K. & Otonkoski, T., 9 Nov 2018, In : eLife. 7, 35 p., 38519.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Dusp16 Deficiency Causes Congenital Obstructive Hydrocephalus and Brain Overgrowth by Expansion of the Neural Progenitor Pool

Zega, K., Jovanovic, V. M., Vitic, Z., Niedzielska, M., Knaapi, L., Jukic, M. M., Partanen, J., Friedel, R. F., Lang, R. & Brodski, C., 9 Nov 2017, In : Frontiers in Molecular Neuroscience. 10, 15 p., 372.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Inactivation of GATA cofactors Fog1 and Fog2 impairs the development of midbrain GABAergic neurons

Tikker, L., Lahti, L. S., Estartús, N. & Partanen, J. M., Jul 2017, p. S94. 1 p.

Research output: Conference materialsAbstractResearch

Open Access

Melanoblast development coincides with the late emerging cells from the dorsal neural tube in turtle Trachemys scripta

Rice, R., Cebra-Thomas, J., Haugas, M., Partanen, J., Rice, D. P. C. & Gilbert, S. F., 21 Sep 2017, In : Scientific Reports. 7, 11 p., 12063.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Prizes

Medix price 2008

Juha Partanen (Recipient), 2008

Prize: Prizes and awards

Medix prize 2004

Juha Partanen (Recipient), 2004

Prize: Prizes and awards

Activities 1999 2015

Examination of doctoral dissertation Jokinen

Juha Partanen (Pre-examiner)
2015

Activity: Examination typesPre-examiner of doctoral thesis

Examination of doctoral dissertation Hakanen

Juha Partanen (Pre-examiner)
2014

Activity: Examination typesPre-examiner of doctoral thesis

Examination of doctoral dissertation Zarkada

Juha Partanen (Pre-examiner)
2014

Activity: Examination typesPre-examiner of doctoral thesis

Examination of doctoral dissertation Fang

Juha Partanen (Pre-examiner)
2013

Activity: Examination typesPre-examiner of doctoral thesis

Suomen kehitysbiologian seura (External organisation)

Juha Partanen (Chair)
20132015

Activity: Membership typesMembership or other role of body in private company/organisation