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Kaarle Franssila

  • Finland

1990 …2019
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Publications 1990 2019

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2019

Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans

Kaasinen, E., Kuismin, O., Rajamäki, K., Ristolainen, H., Aavikko, M., Kondelin, J., Saarinen, S., Berta, D. G., Katainen, R., Hirvonen, E. A. M., Karhu, A., Taira, A., Tanskanen, T., Alkodsi, A., Taipale, M., Morgunova, E., Franssila, K., Lehtonen, R., Mäkinen, M., Aittomäki, K. & 15 othersPalotie, A., Kurki, M., Pietiläinen, O., Hilpert, M., Saarentaus, E., Niinimäki, J., Junttila, J., Kaikkonen, K., Vahteristo, P., Skoda, R. C., Seppänen, M. R. J., Eklund, K. K., Taipale, J., Kilpivaara, O. & Aaltonen, L. A., 19 Mar 2019, In : Nature Communications. 10, 17 p., 1252.

Research output: Contribution to journalArticleScientificpeer-review

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2013

High Familial Risk in Nodular Lymphocyte-Predominant Hodgkin Lymphoma

Saarinen, S., Pukkala, E., Vahteristo, P., Makinen, M. J., Franssila, K. & Aaltonen, L. A., 1 Mar 2013, In : Journal of Clinical Oncology. 31, 7, p. 938-943 6 p.

Research output: Contribution to journalArticleScientificpeer-review

2011

Analysis of KLHDC8B in familial nodular lymphocyte predominant Hodgkin lymphoma

Saarinen, S., Vahteristo, P., Launonen, V., Franssila, K., Kivirikko, S., Lehtonen, R., Bain, B. J., Bauduer, F., Unal, A., Aaltonen, L. A. & Aittomaki, K., 2011, In : British Journal of Haematology. 154, 3, p. 413-415 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Exome sequencing reveals germline NPAT mutation as a candidate risk factor for Hodgkin lymphoma

Saarinen, S., Aavikko, M., Aittomaki, K., Launonen, V., Lehtonen, R., Franssila, K., Lehtonen, H. J., Kaasinen, E., Broderick, P., Tarkkanen, J., Bain, B. J., Bauduer, F., Unal, A., Swerdlow, A. J., Cooke, R., Makinen, M. J., Houlston, R., Vahteristo, P. & Aaltonen, L. A., 2011, In : Blood. 118, 3, p. 493-498 6 p.

Research output: Contribution to journalArticleScientificpeer-review

2007

RAF-1 over-expression does condition survival of patients affected by aggressive mantle cell lymphoma: [letters to the editor]

Nagy, B., Galimbert, S., Benedetti, E., Caracciolo, F., Pacani, S., Vilpo, J., Ferrer, A., Elonen, E., Franssila, K., Knuutila, S. & Petrini, M., 2007, In : Leukemia Research. 31, 11, p. 1595-1597 3 p.

Research output: Contribution to journalArticleScientificpeer-review

2006

Platelet-derived growth factor receptor family mutations in gastrointestinal stromal tumours

Sihto, H., Franssila, K., Tanner, M., Vasama-Nolvi, C., Sarlomo-Rikala, M., Nupponen, N., Joensuu, H. & Isola, J., 2006, In : Scandinavian Journal of Gastroenterology. 41, 7, p. 805-811 7 p.

Research output: Contribution to journalArticleScientificpeer-review

2005

The role of microRNA genes in papillary thyroid carcinoma

He, HL., Jazdzewski, K., Li, W., Liyanarachchi, S., Nagy, R., Volinia, S., Calin, GA., Liu, CG., Franssila, K., Suster, S., Kloos, RT., Croce, CM. & de la Chapelle, A., 27 Dec 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 52, p. 19075-19080 6 p.

Research output: Contribution to journalArticleScientificpeer-review

2004

Autologous stem cell transplantation in adult patients with peripheral T-cell lymphoma: a nation-wide survey

Jantunen, E., Wiklund, T., Juvonen, E., Putkonen, M., Lehtinen, T., Kuittinen, O., Franssila, K., Soderstrom, K. O., Leppa, S., Elonen, E., Remes, K. & Nousiainen, T., 2004, In : Bone Marrow Transplantation. 33, p. 405-410 6 p.

Research output: Contribution to journalArticleScientificpeer-review

2003

Abnormal expression of apoptosis-related genes in haematological malignancies: overexpression of MYC is poor prognostic sign in mantle cell lymphoma

Nagy, B., Lundan, T., Larramendy, ML., Aalto, Y., Zhu, Y., Niini, T., Edgren, H., Ferrer, A., Vilpo, J., Elonen, E., Vettenranta, K., Franssila, K. & Knuutila, S., Feb 2003, In : British Journal of Haematology. 120, 3, p. 434-441 8 p.

Research output: Contribution to journalArticleScientificpeer-review

AMES, MACIS, and TNM prognostic classifications in papillary thyroid carcinoma

Voutilainen, P., Siironen, P., Franssila, K. O., Sivula, A., Haapiainen, R. K. & Haglund, C. H., 2003, In : Anticancer Research. 23, p. 4283-4288 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Lymphotoxin beta expression is high in chronic lymphocytic leukemia but low in small lymphocytic lymphoma: a quantitative real-time reverse transcriptase polymerase chain reaction analysis

Nagy, B., Ferrer, A., Larramendy, ML., Galimberti, S., Aalto, Y., Casas, S., Vilpo, J., Ruutu, T., Vettenranta, K., Franssila, K. & Knuutila, S., Jun 2003, In : Haematologica. 88, 6, p. 654-658 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Predictive factors for blastoid transformation in the common variant of mantle cell lymphoma

Raty, R., Franssila, K., Jansson, S-E., Joensuu, H., Wartiovaara-Kautto, U. & Elonen, E., 2003, In : European Journal of Cancer. 39, 3, p. 321-329 9 p.

Research output: Contribution to journalArticleScientificpeer-review

2002

Alterations in the suppressor gene PPP2R1B in parathyroid hyperplasias and adenomas

Hemmer, S., Wasenius, V-M., Haglund, C. H., Zhu, Y., Knuutila, Y. S., Franssila, K. O. & Joensuu, H. T., 2002, In : Cancer Genetics and Cytogenetics. 134, p. 13-17 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Investigatory and analytical approaches to differential gene expression profiling in mantle cell lymphoma

Zhu, Y., Hollmen, J., Raty, R., Aalto, Y., Nagy, B., Elonen, E., Kere, J., Mannila, H., Franssila, K. & Knuutila, S., 2002, In : British Journal of Haematology. 2002, 119, p. 905-915 11 p.

Research output: Contribution to journalArticleScientificpeer-review

2001

Chromosomally clonal T cells in the skin, blood, or lymph nodes of two Sezary syndrome patients express CD45RA, CD45RO, CDw150, and interleukin-4, but no interleukin-2 or interferon-gamma

Karenko, L., Nevala, H., Raatikainen, M., Franssila, K. & Ranki, A., Jan 2001, In : Journal of Investigative Dermatology. 116, 1, p. 188-193 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Deletion of 11q23 and cyclin D1 overexpression are frequent aberrations in parathyroid adenomas

Hemmer, S., Wasenius, V-M., Haglund, C. H., Zhu, Y., Knuutila, Y. S., Franssila, K. O. & Joensuu, H. T., 2001, In : The American Journal of Pathology. 158, 4, p. 1355-62 8 p.

Research output: Contribution to journalArticleScientificpeer-review

PPP2R1B gene in chronic lymphocytic leukemias and mantle cell lymphomas

Zhu, Y., Loukola, A., Monni, O., Kuokkanen, K., Franssila, K., Elonen, E., Vilpo, J., Joensuu, H., Kere, J., Aaltonen, L. & Knuutila, S., 2001, In : Leukemia. 2001, 41, p. 177-183 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Prognosis after lymph node recurrence in papillary thyroid carcinoma depends on age

Voutilainen, P. E., Multanen, M. M., Leppäniemi, A. K., Haglund, C. H., Haapiainen, R. K. & Franssila, K. O., 2001, In : Thyroid. 11, 10, p. 953-957 5 p.

Research output: Contribution to journalArticleScientificpeer-review

1999

MIB-1 immunoreactivity correlates with blood vessel density and survival in disseminated malignant melanoma

Vlaykova, T., Talve, L., Hahka-Kemppinen, M., Hernberg, M., Muhonen, T., Franssila, K., Collan, Y. & Pyrhonen, S., 1999, In : Oncology. 57, 3, p. 242-252 11 p.

Research output: Contribution to journalArticleScientificpeer-review

1998

Gain of 3q and deletion of 11q22 are frequent aberrations in mantle cell lymphoma

Monni, O., Räty, R., Elonen, E., Franssila, K., Teerenhovi, L., Joensuu, H. & Knuutila, S., Apr 1998, In : Genes, Chromosomes & Cancer. 21, 4, p. 298-307 10 p.

Research output: Contribution to journalArticleScientificpeer-review

1997

BCL2 overexpression associated with chromosomal amplification in diffuse large B-cell lymphoma

Monni, O., Joensuu, H., Franssila, K., Klefström, J., Alitalo, K. & Knuutila, S., 1997, In : Blood. 90, p. 1168-1174 7 p.

Research output: Contribution to journalArticleScientificpeer-review

1996

DNA copy number changes in diffuse large B-cell lymphoma - Comparative genomic hybridization study

Monni, O., Joensuu, H., Franssila, K. & Knuutila, S., 15 Jun 1996, In : Blood. 87, 12, p. 5269-5278 10 p.

Research output: Contribution to journalArticleScientificpeer-review

1994

EFFECT OF VITAMIN-E AND BETA-CAROTENE ON THE INCIDENCE OF LUNG-CANCER AND OTHER CANCERS IN MALE SMOKERS

HEINONEN, O. P., HUTTUNEN, J. K., ALBANES, D., HAAPAKOSKI, J., PALMGREN, J., PIETINEN, P., PIKKARAINEN, J., RAUTALAHTI, M., VIRTAMO, J., EDWARDS, B. K., GREENWALD, P., HARTMAN, A. M., TAYLOR, P. R., HAUKKA, J., JARVINEN, P., MALILA, N., RAPOLA, S., JOKINEN, P., KARJALAINEN, J., LAURONEN, J. & 103 othersMUTIKAINEN, J., SARJAKOSKI, M., SUORSA, A., TIAINEN, M., VERKASALO, M., BARRETT, M., ALFTHAN, G., EHNHOLM, C., GREF, C. G., SUNDVALL, J., HAAPA, E., OVASKAINEN, M. L., PALVAALHOLA, M., ROOS, E., PUKKALA, E., TEPPO, L., FRICK, H., PASTERNACK, A., BROWN, B. W., DEMETS, D. L., KOKKOLA, K., TALA, E., AALTO, E., MAENPAA, V., TIENHAARA, L., JARVINEN, M., KUULIALA, I., LINKO, L., MIKKOLA, E., NYRHINEN, J., RONKANEN, A., VUORELA, A., KOSKINEN, S., LOHELA, P., VILJANEN, T., GODENHJELM, K., KALLIO, T., KASKINEN, M., HAVU, M., KIRVES, P., TAUBERT, K., ALKIO, H., KOSKINEN, R., LAINE, K., MAKITALO, K., RASTAS, S., TANI, P., NIEMISTO, M., SELLERGREN, T. L., AIKAS, C., PEKKANEN, P. S., TARVALA, R., ALANKO, K., MAKIPAJA, K., VAARA, S., SIUKO, H., TUOMINEN, V., ALAKETOLA, L., HAAPANEN, A., HAVERI, M., KESKINISULA, L., KOKKO, E., KOSKENKARI, M., LINDEN, P., NURMENNIEMI, A., RANINEN, R., RAUDASKOSKI, T., TOIVAKKA, S. K., VIEROLA, H., KYRONPALOKAUPPINEN, S., SCHOULTZ, E., JAAKKOLA, M., LEHTINEN, E., RAUTASEPPA, K., SAARIKOSKI, M., LIIPPO, K., REUNANEN, K., SALOMAA, E. R., ETTINGER, D., HIETANEN, P., MAENPAA, H., TEERENHOVI, L., PROUT, G., TASKINEN, E., ASKIN, F., EROZAN, Y., NORDLING, S., VIROLAINEN, M., KOSS, L., SIPPONEN, P., LEWIN, K., FRANSSILA, K., KARKKAINEN, P., HEINONEN, M., HYVONEN, L., KOIVISTOINEN, P., OLLILAINEN, V., PIIRONEN, V., VARO, P., BILHUBER, W., SALKELD, R., SCHALCH, W. & SPEISER, R., 1994, In : New England Journal of Medicine. 330, 15, p. 1029-1035 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Major and minor breakpoint sites of chromosomal translocation t(14;18) in subtypes of non-Hodgkin lymphomas

Klefström, J., FRANSSILA, K., Peltomäki, P., KAARTINEN, M., SOLIN, M. L. & Knuutila, S., 1994, In : Leukemia Research. 18, p. 245-250 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Two novel human B-cell lymphoma lines of lymphatic follicle origin: cytogenetic, molecular genetic and histopathological characterisation

Knuutila, S., Klefström, J., SZYMANSKA, J., LAKKALA, T., Peltomäki, P., ERAY, M., TEERENHOVI, L., ELONEN, E., FRANSSILA, K. O. & KAARTINEN, M., 1994, In : European Journal of Haematology. 52, p. 65-72 8 p.

Research output: Contribution to journalArticleScientificpeer-review