No photo of Kaija-Leena Kolho
  • PL 63 (Haartmaninkatu 8)

    00014

    Finland

1983 …2020

Research output per year

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Publications

2020

Antibiotics in early life associate with specific gut microbiota signatures in a prospective longitudinal infant cohort

Korpela, K., Salonen, A., Saxen, H., Nikkonen, A., Peltola, V., Jaakkola, T., de Vos, W. & Kolho, K-L., Sep 2020, In : Pediatric Research. 88, 3, p. 438–443 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Concentration of fecal calprotectin in 11,255 children aged 0-18 years

Kolho, K-L. & Alfthan, H., 14 Jul 2020, In : Scandinavian Journal of Gastroenterology. 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Decreased airway epithelial ion transport was associated with the severity of the respiratory syncytial virus infection and complications in infants

Kaskinen, A., Alexandersson, A., Andersson, S., Saxén, H., Peltola, V., Kolho, K-L. & Helve, O., 11 May 2020, In : Acta Paediatrica. 3 p.

Research output: Contribution to journalEditorialScientificpeer-review

Open Access
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Infliximab and its biosimilar produced similar first-year therapy outcomes in patients with inflammatory bowel disease

Nikkonen, A. & Kolho, K-L., Apr 2020, In : Acta Paediatrica. 109, 4, p. 836-841 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Infliximab in young paediatric IBD patients: it is all about the dosing

ESPGHAN, Jongsma, M. M. E., Winter, D. A., Huynh, H. Q., Kolho, K-L. & de Ridder, L., 19 Aug 2020, In : European journal of pediatrics. 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Letter: suicide risk among adult inflammatory bowel disease patients. Authors' reply

Malham, M., Jakobsen, C., Paerregaard, A., Hald, M., Virta, L., Kolho, K-L. & Wewer, V., Jun 2020, In : Alimentary Pharmacology & Therapeutics. 51, 11, p. 1214-1215 2 p.

Research output: Contribution to journalLetterScientific

Upper endoscopy for non-acute non-specific symptoms is seldom beneficial for children under the age of seven

Helin, N., Kolho, K-L., Rintala, R. & Merras-Salmio, L., Apr 2020, In : Acta Paediatrica. 109, 4, p. 827-835 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2019

A 30-year follow-up study of patients with Melkersson-Rosenthal syndrome shows an association to inflammatory bowel disease

Haaramo, A., Kolho, K-L., Pitkäranta, A. & Kanerva, M., Feb 2019, In : Annals of Medicine. 51, 2, p. 149-155 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Cohort profile: Finnish Health and Early Life Microbiota (HELMi) longitudinal birth cohort

Korpela, K., Dikareva, E., Hanski, E., Kolho, K-L., De Vos, W. M. & Salonen, A., 2019, In : BMJ Open. 9, 6, 7 p., e028500.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Editorial: suicide and IBD-a call to action. Authors' reply

Malham, M., Jakobsen, C., Hald, M., Paerregaard, A., Virta, L. J., Kolho, K-L. & Wewer, V., Jul 2019, In : Alimentary Pharmacology & Therapeutics. 50, 1, p. 106-107 2 p.

Research output: Contribution to journalEditorialScientific

Open Access
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IBD-hoitajasta hyötyä tulehduksellisten suolistosairauksien hoidossa

Molander, P. & Kolho, K-L., 2019, In : Suomen lääkärilehti. 74, 6, p. 304-305 2 p.

Research output: Contribution to journalArticleProfessional

Open Access
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Inflammatoriska tarmsjukdomar hos barn - ett växande problem

Kolho, K-L., 2019, In : Finska Läkaresällskapets Handlingar. 179, 1, p. 58-63 6 p.

Research output: Contribution to journalArticleProfessional

Open Access
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Intestinal glucocorticoid synthesis enzymes in pediatric inflammatory bowel disease patients

Ahmed, A., Schwaderer, J., Hantusch, A., Kolho, K-L. & Brunner, T., Sep 2019, In : Genes and Immunity. 20, 7, p. 566-576 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Is home monitoring of inflammatory bowel disease feasible? A randomized controlled study

Puolanne, A-M., Kolho, K-L., Alfthan, H. & Färkkilä, M., 3 Jul 2019, In : Scandinavian Journal of Gastroenterology. 54, 7, p. 849-854 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Keliakia: KÄYPÄ HOITO -SUOSITUS (Päivitystiivistelmä)

Kaukinen, K., Kurppa, K., Schwab, U., Hervonen, K., Kolho, K-L., Anthoni, S., Kukkonen-Harjula, K. & Komulainen, J., 2019, In : Duodecim. 135, 2, p. 211-212 2 p.

Research output: Contribution to journalArticleProfessional

Open Access
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Nutritional risk screening-a cross-sectional study in a tertiary pediatric hospital

Tuokkola, J., Hilpi, J., Kolho, K-L., Orell, H. & Merras-Salmio, L., 25 Mar 2019, In : Journal of Health Population and Nutrition. 38, 4 p., 8.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Oral and Otorhinolaryngological Findings in Adults Who Were Diagnosed With Pediatric Onset Crohn's Disease A Controlled Study

Haaramo, A., Alapulli, H., Aine, L., Tuokkola, J., Saarnisto, U., Roine, R. P., Pitkäranta, A. & Kolho, K-L., Aug 2019, In : Journal of Clinical Gastroenterology. 53, 7, p. E269-E275 7 p.

Research output: Contribution to journalArticleScientificpeer-review

The incidence of cancer and mortality in paediatric onset inflammatory bowel disease in Denmark and Finland during a 23-year period: a population-based study

Malham, M., Jakobsen, C., Paerregaard, A., Virta, L. J., Kolho, K-L. & Wewer, V., Jul 2019, In : Alimentary Pharmacology & Therapeutics. 50, 1, p. 33-39 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Ursodeoxycholic Acid Therapy in Pediatric Primary Sclerosing Cholangitis: Predictors of Gamma Glutamyltransferase Normalization and Favorable Clinical Course

Deneau, M., Perito, E., Ricciuto, A., Gupta, N., Kamath, B. M., Palle, S., Vitola, B., Smolka, V., Ferrari, F., Amir, A. Z., Miloh, T., Papadopoulou, A., Mohan, P., Mack, C., Kolho, K-L., Iorio, R., El-Matary, W., Venkat, V., Chan, A., Saubermann, L. & 5 others, Valentino, P. L., Shah, U., Miethke, A., Lin, H. & Jensen, M. K., Jun 2019, In : The Journal of Pediatrics. 209, p. 92-+ 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2018

Cronin tauti yleistyy lapsilla - tunnistatko suumuutokset?

Saarnisto, U., Alapulli, H., Kolho, K-L. & Liisa, A., 2018, In : Suomen hammaslääkärilehti. 25, 3, p. 20-26 7 p.

Research output: Contribution to journalArticleScientificpeer-review

ECCO-ESCP Consensus on Surgery for Crohn's Disease

Bemelman, W. A., Warusavitarne, J., Sampietro, G. M., Serclova, Z., Zmora, O., Luglio, G., van Overstraeten, A. D. B., Burke, J. P., Buskens, C. J., Colombo, F., Dias, J. A., Eliakim, R., Elosua, T., Gecim, I. E., Kolacek, S., Kierkus, J., Kolho, K-L., Lefevre, J. H., Millan, M., Panis, Y. & 7 others, Pinkney, T., Russell, R. K., Shwaartz, C., Vaizey, C., Yassin, N., D'Hoore, A. & European Crohn's & Colitis Org, Jan 2018, In : Journal of Crohn's and Colitis. 12, 1, p. 1-16 16 p.

Research output: Contribution to journalArticleScientificpeer-review

Fecal Calprotectin Test Performed at Home: A Prospective Study of Pediatric Patients with Inflammatory Bowel Disease

Piekkala, M., Alfthan, H., Merras-Salmio, L., Puustinen Wikström, A., Heiskanen, K., Jaakkola, T., Klemetti, P., Färkkilä, M. & Kolho, K-L., Jun 2018, In : Journal of Pediatric Gastroenterology and Nutrition. 66, 6, p. 926-931 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Gamma Glutamyltransferase Reduction Is Associated With Favorable Outcomes in Pediatric Primary Sclerosing Cholangitis

Deneau, M. R., Mack, C., Abdou, R., Amin, M., Amir, A., Auth, M., Bazerbachi, F., Broderick, A. M., Chan, A., DiGuglielmo, M., El-Matary, W., El-Youssef, M., Ferrari, F., Furuya, K. N., Gottrand, F., Gupta, N., Homan, M., Jensen, M. K., Kamath, B. M., Kim, K. M. & 22 others, Kolho, K-L., Konidari, A., Koot, B., Iorio, R., Martinez, M., Mohan, P., Palle, S., Papadopoulou, A., Ricciuto, A., Saubermann, L., Sathya, P., Shteyer, E., Smolka, V., Tanaka, A., Valentino, P. L., Varier, R., Venkat, V., Vitola, B., Vos, M. B., Woynarowski, M., Yap, J. & Miloh, T., Nov 2018, In : Hepatology communications. 2, 11, p. 1369-1378 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Gastrointestinal Symptoms of Food Challenge-proven Non-IgE Cow's Milk Allergy Are Dissipated by Early School Age

Helin, N., Kolho, K-L., Qvist, E., Mäkelä, M. & Merras-Salmio, L., Apr 2018, In : Journal of Pediatric Gastroenterology and Nutrition. 66, 4, p. 598-602 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Malignancy and mortality in paediatric-onset inflammatory bowel disease: a 3-year prospective, multinational study from the paediatric IBD Porto group of ESPGHAN

Paediat IBD Porto Grp ESPGHAN, Sep 2018, In : Alimentary Pharmacology & Therapeutics. 48, 5, p. 523-537 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Outcomes of Surgical Management of Familial Intrahepatic Cholestasis 1 and Bile Salt Export Protein Deficiencies

Bull, L. N., Pawlikowska, L., Strautnieks, S., Jankowska, I., Czubkowski, P., Dodge, J. L., Emerick, K., Wanty, C., Wali, S., Blanchard, S., Lacaille, F., Byrne, J. A., van Eerde, A. M., Kolho, K-L., Houwen, R., Lobritto, S., Hupertz, V., McClean, P., Mieli-Vergani, G., Sokal, E. & 4 others, Rosenthal, P., Whitington, P. F., Pawlowska, J. & Thompson, R. J., May 2018, In : Hepatology communications. 2, 5, p. 515-528 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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The impacts of an inflammatory bowel disease nurse specialist on the quality of care and costs in Finland

Molander, P., Jussila, A., Toivonen, T., Makkeli, P., Alho, A. & Kolho, K-L., 2 Dec 2018, In : Scandinavian Journal of Gastroenterology. 53, 12, p. 1463-1468 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2017

Anti-TNFα Treatment After Surgical Resection for Crohn's Disease Is Effective Despite Previous Pharmacodynamic Failure

Assa, A., Bronsky, J., Kolho, K-L., Zarubova, K., de Meij, T., Ledder, O., Sladek, M., van Biervliet, S., Strisciuglio, C. & Shamir, R., May 2017, In : Inflammatory Bowel Diseases. 23, 5, p. 791-797 7 p.

Research output: Contribution to journalArticleScientificpeer-review

C4B gene influences intestinal microbiota through complement activation in patients with paediatric-onset inflammatory bowel disease

Nissilä, E., Korpela, K., Lokki, A. I., Paakkanen, R., Jokiranta, S., de Vos, W. M., Lokki, M. -L., Kolho, K. -L. & Meri, S., Dec 2017, In : Clinical and Experimental Immunology. 190, 3, p. 394-405 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Declining trend in the incidence of biopsy-verified coeliac disease in the adult population of Finland, 2005-2014

Virta, L. J., Saarinen, M. M. & Kolho, K. -L., Dec 2017, In : Alimentary Pharmacology & Therapeutics. 46, 11-12, p. 1085-1093 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Detailed Follow-up Study of Pediatric Orofacial Granulomatosis Patients

Haaramo, A., Alapulli, H., Aine, L., Saarnisto, U., Tuokkola, J., Ruuska, T., Sipponen, T., Pitkaranta, A. & Kolho, K-L., Oct 2017, In : Journal of Pediatric Gastroenterology and Nutrition. 65, 4, p. 388-393 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Faecal and serum metabolomics in paediatric inflammatory bowel disease

Kolho, K-L., Pessia, A., Jaakkola, T., de Vos, W. M. & Velagapudi, V., 1 Mar 2017, In : Journal of Crohn's and Colitis. 11, 3, p. 321-334 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Fecal calprotectin in juvenile idiopathic arthritis patients related to drug use

Aalto, K., Lahdenne, P. & Kolho, K-L., 31 Jan 2017, In : Pediatric Rheumatology Online Journal. 15, 7 p., 9.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Human leucocyte antigens B08, DRB103 and DRB113 are significantly associated with autoimmune liver and biliary diseases in Finnish children

Ylinen, E., Salmela, L., Perasaari, J., Jaatinen, T., Tenca, A., Vapalahti, O., Färkkilä, M., Jalanko, H. & Kolho, K-L., Feb 2017, In : Acta Paediatrica. 106, 2, p. 322-326 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Inflammatory Bowel Disease Incidence is on the Continuous Rise Among All Paediatric Patients Except for the Very Young: A Nationwide Registry-based Study on 28-Year Follow-up

Virta, L. J., Saarinen, M. M. & Kolho, K-L., Feb 2017, In : Journal of Crohn's and Colitis. 11, 2, p. 150-156 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Mesalamine Enemas for Induction of Remission in Oral Mesalamine-refractory Pediatric Ulcerative Colitis: A Prospective Cohort Study

Levine, A., Yerushalmi, B., Kori, M., Broide, E., Mozer-Glassberg, Y., Shaoul, R., Kolho, K-L., Shteyer, E., Shamaly, H., Ledder, O., Cohen, S., Peleg, S., Shabat, C. S., Focht, G., Shachmon, E., Boaz, M., On, A. & Turner, D., Aug 2017, In : Journal of Crohn's and Colitis. 11, 8, p. 970-974 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Once-Versus Twice-daily Mesalazine to Induce Remission in Paediatric Ulcerative Colitis: A Randomised Controlled Trial

Turner, D., Yerushalmi, B., Kori, M., Broide, E., Mozer-Glassberg, Y., Shaoul, R., Kolho, K-L., Shteyer, E., Shamaly, H., Ledder, O., Cohen, S., Peleg, S., On, A. & Levine, A., May 2017, In : Journal of Crohn's and Colitis. 11, 5, p. 527-533 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Peräaukon ongelmat lapsilla

Kolho, K-L. & Rintala, R., 2017, Lääkärin käsikirja. Jousimaa, J., Alenius, H., Atula, S., Berghem, N., Kattainen, A., Kunnamo, I., Pelttari, H. & Teikari, M. (eds.). 12. uud. p. ed. Helsinki: Duodecim, p. 1307-1308 2 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Quality Items Required for Running a Paediatric Inflammatory Bowel Disease Centre: An ECCO Paper

Turner, D., Carle, A., Steiner, S. J., Margolis, P. A., Colletti, R. B., Russell, R. K., Levine, A., Kolho, K-L., Ruemmele, F. M. & ImproveCareNow Network, Aug 2017, In : Journal of Crohn's and Colitis. 11, 8, p. 981-987 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Rapid Fecal Calprotectin Test and Symptom Index in Monitoring the Disease Activity in Colonic Inflammatory Bowel Disease

Puolanne, A-M., Kolho, K-L., Alfthan, H., Ristimäki, A., Mustonen, H. & Färkkilä, M., Nov 2017, In : Digestive Diseases and Sciences. 62, 11, p. 3123-3130 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Surgical Management of Crohn Disease in Children: Guidelines From the Paediatric IBD Porto Group of ESPGHAN

Amil-Dias, J., Kolacek, S., Turner, D., Paerregaard, A., Rintala, R., Afzal, N. A., Karolewska-Bochenek, K., Bronsky, J., Chong, S., Fell, J., Hojsak, I., Hugot, J-P., Koletzko, S., Kumar, D., Lazowska-Przeorek, I., Lillehei, C., Lionetti, P., Martin-de-Carpi, J., Pakarinen, M., Ruemmele, F. M. & 8 others, Shaoul, R., Spray, C., Staiano, A., Sugarman, I., Wilson, D. C., Winter, H., Kolho, K-L. & IBD Working Grp ESPGHAN IBD Porto, May 2017, In : Journal of Pediatric Gastroenterology and Nutrition. 64, 5, p. 818-835 18 p.

Research output: Contribution to journalArticleScientificpeer-review

The Natural History of Primary Sclerosing Cholangitis in 781 Children: AMulticenter, International Collaboration

Deneau, M. R., El-Matary, W., Valentino, P. L., Abdou, R., Alqoaer, K., Amin, M., Amir, A. Z., Auth, M., Bazerbachi, F., Broderick, A., Chan, A., Cotter, J., Doan, S., El-Youssef, M., Ferrari, F., Furuya, K. N., Gottrand, M., Gottrand, F., Gupta, N., Homan, M. & 26 others, Kamath, B. M., Kim, K. M., Kolho, K-L., Konidari, A., Koot, B., Iorio, R., Ledder, O., Mack, C., Martinez, M., Miloh, T., Mohan, P., O'Cathain, N., Papadopoulou, A., Ricciuto, A., Saubermann, L., Sathya, P., Shteyer, E., Smolka, V., Tanaka, A., Varier, R., Venkat, V., Vitola, B., Vos, M. B., Woynarowski, M., Yap, J. & Jensen, M. K., Aug 2017, In : Hepatology. 66, 2, p. 518-527 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Tulehdukselliset suolistosairaudet lapsilla

Kolho, K-L., 2017, Lääkärin käsikirja. Jousimaa, J., Alenius, H., Atula, S., Berghem, N., Kattainen, A., Kunnamo, I., Pelttari, H. & Teikari, M. (eds.). 12. uud. p. ed. Helsinki: Duodecim, p. 1150-1151 2 p.

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Tulehdukselliset suolistosairaudet - mikä vialla?

Kolho, K-L. & Färkkilä, M., 2017, In : Duodecim. 133, 18, p. 1701-1709 9 p.

Research output: Contribution to journalArticleProfessional

Open Access
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Vedolizumab in Paediatric Inflammatory Bowel Disease: A Retrospective Multi-Centre Experience From the Paediatric IBD Porto Group of ESPGHAN

Ledder, O., Assa, A., Levine, A., Escher, J. C., De Ridder, L., Ruemmele, F., Shah, N., Shaoul, R., Wolters, V. M., Rodrigues, A., Uhlig, H. H., Posovsky, C., Kolho, K-L., Jakobsen, C., Cohen, S., Shouval, D. S., de Meij, T., Martin-de-Carpi, J., Richmond, L., Bronsky, J. & 2 others, Friedman, M. & Turner, D., Oct 2017, In : Journal of Crohn's and Colitis. 11, 10, p. 1230-1237 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
2016

Assessment of disease activity in pediatric ulcerative colitis

Kolho, K-L., Oct 2016, In : Expert Review of Gastroenterology and Hepatology. 10, 10, p. 1127-1134 8 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Clinical course and prognosis of pediatric-onset primary sclerosing cholangitis

Tenca, A., Farkkila, M., Arola, J., Jaakkola, T., Penagini, R. & Kolho, K-L., Aug 2016, In : United european gastroenterology journal. 4, 4, p. 562-569 8 p.

Research output: Contribution to journalArticleScientificpeer-review