Kimmo Palin

Phone+358504486341, +358294125681
Emailkimmo.palinhelsinkifi

PL 63 (Haartmaninkatu 8)
00014
Finland
Finland

Research activity per year

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Fields of Science

113 Computer and information sciences
Computational biology
Computational systems biology
3111 Biomedicine
1182 Biochemistry, cell and molecular biology
1184 Genetics, developmental biology, physiology

44 Article
1 Doctoral Thesis

Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries
Fernandez-Rozadilla, C., Timofeeva, M., Chen, Z., Law, P., Thomas, M., Bien, S., Diez-Obrero, V., Li, L., Fernandez-Tajes, J., Palles, C., Sherwood, K., Harris, S., Svinti, V., McDonnell, K., Farrington, S., Studd, J., Vaughan-Shaw, P., Shu, X., Long, J., Cai, Q., & 190 othersGuo, X., Lu, Y., Scacheri, P., Studd, J., Huyghe, J., Harrison, T., Shibata, D., Haiman, C., Devall, M., Schumacher, F., Melas, M., Rennert, G., Obon-Santacana, M., Martin-Sanchez, V., Moratalla-Navarro, F., Oh, J. H., Kim, J., Jee, S. H., Jung, K. J., Kweon, S-S., Shin, M-H., Shin, A., Ahn, Y-O., Kim, D-H., Oze, I., Wen, W., Matsuo, K., Matsuda, K., Tanikawa, C., Ren, Z., Gao, Y-T., Jia, W-H., Potter, J., Jenkins, M., Win, A. K., Pai, R., Figueiredo, J., Haile, R., Gallinger, S., Woods, M., Newcomb, P., Shibata, D., Cheadle, J., Kaplan, R., Maughan, T., Kerr, R., Kerr, D., Kirac, I., Boehm, J., Mecklin, L-P., Jousilahti, P., Knekt, P., Aaltonen, L., Rissanen, H., Pukkala, E., Eriksson, J., Cajuso, T., Hanninen, U., Kondelin, J., Palin, K., Tanskanen, T., Renkonen-Sinisalo, L., Zanke, B., Männistö, S., Albanes, D., Weinstein, S., Ruiz-Narvaez, E., Palmer, J., Buchanan, D., Platz, E., Visvanathan, K., Ulrich, C., Siegel, E., Brezina, S., Gsur, A., Campbell, P., Chang-Claude, J., Hoffmeister, M., Brenner, H., Slattery, M., Potter, J., Tsilidis, K., Schulze, M., Gunter, M., Murphy, N., Castells, A., Castellvi-Bel, S., Moreira, L., Arndt, V., Shcherbina, A., Stern, M., Pardamean, B., Bishop, T., Giles, G., Southey, M., Idos, G., McDonnell, K., Abu-Ful, Z., Greenson, J., Shulman, K., Lejbkowicz, F., Offit, K., Su, Y-R., Steinfelder, R., Keku, T., van Guelpen, B., Hudson, T., Hampel, H., Pearlman, R., Berndt, S., Hayes, R., Martinez, M. E., Thomas, S., Corley, D., Pharoah, P., Larsson, S., Yen, Y., Lenz, H-J., White, E., Li, L., Doheny, K., Pugh, E., Shelford, T., Chan, A., Cruz-Correa, M., Lindblom, A., Shibata, D., Joshi, A., Schafmayer, C., Scacheri, P., Kundaje, A., Nickerson, D., Schoen, R., Hampe, J., Stadler, Z., Vodicka, P., Vodickova, L., Vymetalkova, V., Papadopoulos, N., Edlund, C., Gauderman, W., Thomas, D., Shibata, D., Toland, A., Markowitz, S., Kim, A., Gruber, S., van Duijnhoven, F., Feskens, E., Sakoda, L., Gago-Dominguez, M., Wolk, A., Naccarati, A., Pardini, B., FitzGerald, L., Lee, S. C., Ogino, S., Bien, S., Kooperberg, C., Li, C., Lin, Y., Prentice, R., Qu, C., Bezieau, S., Tangen, C., Mardis, E., Yamaji, T., Sawada, N., Iwasaki, M., Haiman, C., Le Marchand, L., Wu, A., Qu, C., McNeil, C., Coetzee, G., Hayward, C., Deary, I., Harris, S., Theodoratou, E., Reid, S., Walker, M., Ooi, L. Y., Moreno, V., Casey, G., Gruber, S., Tomlinson, I., Zheng, W., Dunlop, M., Houlston, R. & Peters, U., Jan 2023, In: Nature Genetics. 55, 1, p. 89-+ 18 p.
Research output: Contribution to journal › Article › Scientific › peer-review
Inherited mutations affecting the SRCAP complex are central in moderate-penetrance predisposition to uterine leiomyomas
Välimäki, N., Jokinen, V., Cajuso, T., Kuisma, H., Taira, A., Dagnaud, O., Ilves, S., Kaukomaa, J., Pasanen, A., Palin, K., Heikinheimo, O., Bützow, R., Aaltonen, L. A. & Karhu, A., 2 Mar 2023, In: American Journal of Human Genetics. 110, 3, p. 460-474 16 p.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
Molecular subclass of uterine fibroids predicts tumor shrinkage in response to ulipristal acetate
Kolterud, A., Välimäki, N., Kuisma, H., Patomo, J., Ilves, S. T., Mäkinen, N., Kaukomaa, J., Palin, K., Kaasinen, E., Karhu, A., Pasanen, A., Bützow, R., Heikinheimo, O., Kallner, H. K. & Aaltonen, L. A., Apr 2023, In: Human Molecular Genetics. 32, 7, p. 1063–1071 9 p.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
Vitamin C boosts DNA demethylation in TET2 mutation carriers
Taira, A., Palin, K., Kuosmanen, A., Välimäki, N., Kuittinen, O., Kuismin, O., Kaasinen, E., Rajamäki, K. & Aaltonen, L. A., 14 Jan 2023, In: Clinical epigenetics. 15, 1, 13 p., 7.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
MTG16 regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors
Brown, R. E., Jacobse, J., Anant, S. A., Blunt, K. M., Chen, B., Vega, P. N., Jones, C. T., Pilat, J. M., Revetta, F., Gorby, A. H., Stengel, K. R., Choksi, Y. A., Palin, K., Piazuelo, M. B., Washington, M. K., Lau, K. S., Goettel, J. A., Hiebert, S. W., Short, S. P. & Williams, C. S., 23 May 2022, In: JCI INSIGHT. 7, 10, 22 p., 153045.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File

1 Active

iCAN - Digital precision cancer medicine for discoveries and improved treatments
Mäkelä, T., Adhikari, S., Aldahdooh, J. M. F., Ariotta, V., Atarsaikhan, G., Bao, J., Barreiro, K., Bhalke, M. S., Chernenko, A., Dashi, G., Eloranta, K., Eriksson, M. R., Gerber, L. J., Grönholm, M., Heistman, V., Henriksson, M. E. J., Ikonen, N., Jansouz, S., Junquera Mencía, A., Kampanellou, E., Karhemo, P., Kekkonen, J., Kolikova, Y., Krami Senhaji, O., Kuosmanen, A., Kuusela, S., Kücükel, H., Langohr, L., Le Joncour, V., Leivonen, S., Liljeström, M., Lindgren, H., Luck, T. J., Lähdeniemi, I. A. K., Maljanen, K. J., Marchi, G., Miihkinen, M. S., Nader, K. M., Nagaraj, A., Niemeyer, F., Niemiec, I., Palin, K., Parsons, A. O., Pietiäinen, V., Pirinen, I. E., Pirttikoski, A. A., Puhka, M., Quintero, I. B., Rachidi, S. E., Rajalaakso, M. T., Rodosthenous, R., Saad, J., Sanjaya, P., Seppälä, T. T., Seref Vujaklija, C., Shah, S., Sorri, S. P., Suni, V., Suutala, A., Suvela, M., Udayani, J. E., Verkasalo, H. M., Vähärautio, A., Vänttinen, I. M., Västrik, I. & Väänänen, J.
Suomen Akatemia Projektilaskutus
01/09/2022 → 31/12/2026
Project: Academy of Finland: Finnish Flagship Programme

Kimmo Palin

Personal profile

Fields of Science

International and National Collaboration

Dive into details

Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

Inherited mutations affecting the SRCAP complex are central in moderate-penetrance predisposition to uterine leiomyomas

Molecular subclass of uterine fibroids predicts tumor shrinkage in response to ulipristal acetate

Vitamin C boosts DNA demethylation in TET2 mutation carriers

MTG16 regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors

iCAN - Digital precision cancer medicine for discoveries and improved treatments

Kimmo Palin

Personal profile

Fields of Science

International and National Collaboration

Publications

Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

Inherited mutations affecting the SRCAP complex are central in moderate-penetrance predisposition to uterine leiomyomas

Molecular subclass of uterine fibroids predicts tumor shrinkage in response to ulipristal acetate

Vitamin C boosts DNA demethylation in TET2 mutation carriers

MTG16 regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors

Projects

iCAN - Digital precision cancer medicine for discoveries and improved treatments