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Publications 1995 2019

2019

Dasatinib and navitoclax act synergistically to target NUP98-NSD1(+)/FLT3-ITD+ acute myeloid leukemia

Kivioja, J. L., Thanasopoulou, A., Kumar, A., Kontro, M., Yadav, B., Majumder, M. M., Javarappa, K. K., Eldfors, S., Schwaller, J., Porkka, K. & Heckman, C. A., Jun 2019, In : Leukemia. 33, 6, p. 1360-1372 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Elevated expression of S100A8 and S100A9 correlates with resistance to the BCL-2 inhibitor venetoclax in AML

Karjalainen, R., Liu, M., Kumar, A., Malani, D., Parsons, A. O., Kontro, M., Kallioniemi, O., Porkka, K. & Heckman, C., 2019, In : Leukemia.

Research output: Contribution to journalLetterScientificpeer-review

Hemap: An Interactive Online Resource for Characterizing Molecular Phenotypes across Hematologic Malignancies

Pölönen, P., Mehtonen, J., Lin, J., Liuksiala, T., Häyrynen, S., Teppo, S., Mäkinen, A., Kumar, A., Malani, D., Pohjolainen, V., Porkka, K., Heckman, C. A., May, P., Hautamäki, V., Granberg, K. J., Lohi, O., Nykter, M. & Heinäniemi, M., 15 May 2019, In : Cancer Research. 79, 10, p. 2466-2479 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Immune cell constitution in bone marrow microenvironment predicts outcome in adult ALL

Hohtari, H., Bruck, O., Blom, S., Turkki, R., Sinisalo, M., Kovanen, P. E., Kallioniemi, O., Pellinen, T., Porkka, K. & Mustjoki, S., Jul 2019, In : Leukemia. 33, 7, p. 1570-1582 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Multi-parametric single cell evaluation defines distinct drug responses in healthy hematological cells that are retained in corresponding malignant cell types

Majumder, M. M., Leppä, A-M., Hellesøy, M., Dowling, P., Malyutina, A., Kopperud, R., Bazou, D., Andersson, E., Parsons, A., Tang, J., Kallioniemi, O., Mustjoki, S., O'Gorman, P., Wennerberg, K., Porkka, K., Gjertsen, B. T. & Heckman, C. A., 22 Aug 2019, In : Haematologica. p. haematol.2019.217414

Research output: Contribution to journalArticleScientificpeer-review

Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia

Kuusanmäki, H., Leppä, A-M., Pölönen, P., Kontro, M., Dufva, O., Deb, D., Yadav, B., Bruck, O., Kumar, A., Everaus, H., Gjertsen, B. T., Heinäniemi, M., Porkka, K., Mustjoki, S. & Heckman, C., 11 Jul 2019, In : Haematologica.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
2018

Case studies investigating genetic heterogeneity between anatomically distinct bone marrow compartments in acute myeloid leukemia

Ojamies, P. N., Kontro, M., Edgren, H., Ellonen, P., Heckman, C., Porkka, K., Wolf, M. & Kallioniemi, O., 2 Dec 2018, In : Leukemia & lymphoma. 59, 12, p. 3002-3005 4 p.

Research output: Contribution to journalLetterScientificpeer-review

Chimeric NUP98-NSD1 transcripts from the cryptic t(5;11)(q35.2;p15.4) in adult de novo acute myeloid leukemia

Kivioja, J., Lopez Marti, J. M., Kumar, A., Kontro, M., Edgren, H., Parsons, A., Lundan, T., Wolf, M., Porkka, K. & Heckman, C., 2018, In : Leukemia & lymphoma. 59, 3, p. 725-732 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Combined Targeting of BET Family Proteins and BCL2 Is Synergistic in Acute Myeloid Leukemia Cells Overexpressing S100A8 and S100A9

Karjalainen, R., Liu, M., Kumar, A., Parsons, A., He, L., Malani, D. R., Kontro, M., Porkka, K. & Heckman, C. A., 2018, In : Blood. 132

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

Germline alterations in a consecutive series of acute myeloid leukemia

Wartiovaara-Kautto, U., Hirvonen, E. A. M., Pitkänen, E., Heckman, C., Saarela, J., Kettunen, K., Porkka, K. & Kilpivaara, O., Oct 2018, In : Leukemia. 32, 10, p. 2282-2285 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Immune cell contexture in the bone marrow tumor microenvironment impacts therapy response in CML

Bruck, O., Blom, S., Dufva, O., Turkki, R., Chheda, H., Ribeiro, A., Kovanen, P., Aittokallio, T., Koskenvesa, P., Kallioniemi, O., Porkka, K., Pellinen, T. & Mustjoki, S., Jul 2018, In : Leukemia. 32, 7, p. 1643-1656 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Multi-Parametric Single Cell Profiling Defines Distinct Drug Responses in Healthy Hematological Cell Lineages That Are Retained in Corresponding Malignant Cell Types

Majumder, MM., Leppä, A-M., Hellesøy, M., Dowling, P., Malyutina, A., Bazou, D., Andersson, E. I., Parsons, A., Tang, J., Kallioniemi, O-P., Mustjoki, S. M., O'Gorman, P., Wennerberg, J. K., Porkka, K. V. K., Gjertsen, B-T. & Heckman, C. A., 2018, In : Blood. 132

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

Syövän immunologinen täsmähoito geneettisesti muokatuilla T-soluilla

Korhonen, M., Keränen, M., Vettenranta, K., Leppä, S., Ylä-Herttuala, S. & Porkka, K., 2018, In : Duodecim. 134, 16, p. 1592-1599 8 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

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2017

Dasatinib Changes Immune Cell Profiles Concomitant with Reduced Tumor Growth in Several Murine Solid Tumor Models

Hekim, C., Ilander, M., Yan, J., Michaud, E., Smykla, R., Vaha-Koskela, M., Savola, P., Tahtinen, S., Saikko, L., Hemminki, A., Kovanen, P. E., Porkka, K., Lee, F. Y. F. & Mustjoki, S., Feb 2017, In : Cancer immunology research. 5, 2, p. 157-169 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Differentiation status of primary chronic myeloid leukemia cells affects sensitivity to BCR-ABL1 inhibitors

Pietarinen, P. O., Eide, C. A., Ayuda-Duran, P., Potdar, S., Kuusanmaki, H., Andersson, E. I., Mpindi, J. P., Pemovska, T., Kontro, M., Heckman, C. A., Kallioniemi, O., Wennerberg, K., Hjorth-Hansen, H., Druker, B. J., Enserink, J. M., Tyner, J. W., Mustjoki, S. & Porkka, K., 4 Apr 2017, In : Oncotarget. 8, 14, p. 22606-22615 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Early BCR-ABL1 Transcript Decline after 1 Month of Tyrosine Kinase Inhibitor Therapy as an Indicator for Treatment Response in Chronic Myeloid Leukemia

El Missiry, M., Hjorth-Hansen, H., Richter, J., Olson-Stromberg, U., Stenke, L., Porkka, K., Kreutzman, A. & Mustjoki, S., 30 Jan 2017, In : PLoS One. 12, 1, 17 p., 0171041.

Research output: Contribution to journalArticleScientificpeer-review

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Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML

Malani, D., Murumagi, A., Yadav, B., Kontro, M., Eldfors, S., Kumar, A., Karjalainen, R., Majumder, M. M., Ojamies, P., Pemovska, T., Wennerberg, K., Heckman, C., Porkka, K., Wolf, M., Aittokallio, T. & Kallioniemi, O., May 2017, In : Leukemia. 31, 5, p. 1187-1195 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Genomilääketieteen sovelluksia sairauksien hoidossa

Porkka, K., Niemi, M., Leppä, E., Västrik, I., Partanen, J., Ihalainen, J., Jokiranta, S. & Pöllänen, P., 2017, In : Duodecim. 133, 8, p. 782-790 9 p.

Research output: Contribution to journalArticleProfessional

Open Access
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High Amount of PD1+TIM3+ T Helper Cells May Predict Poor Outcome in Adult Acute Lymphoblastic Leukemia

Hohtari, H., Bruck, O., Blom, S., Turkki, R., Ribeiro, A., Sinisalo, M., Kovanen, P., Kallioniemi, O., Pellinen, T., Porkka, K. & Mustjoki, S., 2017, p. 3985. 1 p.

Research output: Conference materialsAbstractResearchpeer-review

HOX gene expression predicts response to BCL-2 inhibition in acute myeloid leukemia

Kontro, M., Kumar, A., Majumder, M. M., Eldfors, S., Parsons, A., Pemovska, T., Saarela, J. S., Yadav, B., Malani, D. R., Fløisand, Y., Höglund, M., Remes, K., Gjertsen, B-T., Kallioniemi, O-P., Wennerberg, J. K., Heckman, C. A. & Porkka, K. V. K., 2017, In : Leukemia. 31, 2, p. 301-309 9 p.

Research output: Contribution to journalArticleScientificpeer-review

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Idelalisib sensitivity and mechanisms of disease progression in relapsed TCF3-PBX1 acute lymphoblastic leukemia

Eldfors, S., Kuusanmäki, H., Kontro, M., Majumder, M. M., Parsons, A., Edgren, H., Pemovska, T., Kallioniemi, O., Wennerberg, K., Gökbuget, N., Burmeister, T., Porkka, K. & Heckman, C. A., 2017, In : Leukemia. 31, 1, p. 51-57 7 p.

Research output: Contribution to journalArticleScientificpeer-review

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Identification of precision treatment strategies for relapsed/refractory multiple myeloma by functional drug sensitivity testing

Majumder, M. M., Silvennoinen, R., Anttila, P., Tamborero, D., Eldfors, S., Yadav, B., Karjalainen, R., Kuusanmaki, H., Lievonen, J., Parsons, A., Suvela, M., Jantunen, E., Porkka, K. & Heckman, C. A., 22 Aug 2017, In : Oncotarget. 8, 34, p. 56338-56350 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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IMMUNOLOGICAL CHARACTERIZATION OF PH plus ALL BONE MARROW BY MULTIPLEX IMMUNOHISTOCHEMISTRY

Hohtari, H., Bruck, O., Blom, S., Turkki, R., Ribeiro, A., Sinisalo, M., Kovanen, P., Kallioniemi, O., Pellinen, T., Porkka, K. & Mustjoki, S., 26 Jun 2017, In : Haematologica. 102, p. 654-654 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Increased proportion of mature NK cells is associated with successful imatinib discontinuation in chronic myeloid leukemia

Ilander, M., Olsson-Stromberg, U., Schlums, H., Guilhot, J., Bruck, O., Lahteenmaki, H., Kasanen, T., Koskenvesa, P., Soderlund, S., Hoglund, M., Markevarn, B., Sjalander, A., Lotfi, K., Dreimane, A., Lubking, A., Holm, E., Bjoreman, M., Lehmann, S., Stenke, L., Ohm, L. & 11 othersGedde-Dahl, T., Majeed, W., Ehrencrona, H., Koskela, S., Saussele, S., Mahon, F-X., Porkka, K., Hjorth-Hansen, H., Bryceson, Y. T., Richter, J. & Mustjoki, S., May 2017, In : Leukemia. 31, 5, p. 1108-1116 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell-induced protection of AML

Karjalainen, R., Pemovska, T., Popa, M., Liu, M., Javarappa, K. K., Majumder, M. M., Yadav, B., Tamborero, D., Tang, J., Bychkov, D., Kontro, M., Parsons, A., Suvela, M., Safont, M. M., Porkka, K., Aittokallio, T., Kallioniemi, O., McCormack, E., Gjertsen, B. T., Wennerberg, K. & 2 othersKnowles, J. & Heckman, C. A., 10 Aug 2017, In : Blood. 130, 6, p. 789-802 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

LOW IL-2 CONCENTRATION FAVORS GENERATION OF EARLY MEMORY T CELLS OVER TERMINAL EEFECTORS DURING CAR T-CELL EXPANSION

Luostarinen, A., Kaartinen, T., Maliniernii, P., Keto, J., Arvas, M., Belt, H., Koponen, J., Loskog, A., Mustjoki, S., Porkka, K., Yla-Herttuala, S. & Korhonen, M., May 2017, In : Cytotherapy. 19, 5, p. S8-S8 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Low interleukin-2 concentration favors generation of early memory T cells over effector phenotypes during chimeric antigen receptor T-cell expansion

Kaartinen, T., Luostarinen, A., Maliniemi, P., Keto, J., Arvas, M., Belt, H., Koponen, J., Loskog, A., Mustjoki, S., Porkka, K., Yla-Herttuala, S. & Korhonen, M., Jun 2017, In : Cytotherapy. 19, 6, p. 689-702 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Monitoring therapy responses at the leukemic subclone level by ultra-deep amplicon resequencing in acute myeloid leukemia

Ojamies, P., Kontro, M., Edgren, H., Ellonen, P., Lagström, S., Almusa, H., Miettinen, T., Eldfors, S., Tamborero, D., Wennerberg, K., Heckman, C., Porkka, K., Wolf, M. & Kallioniemi, O., 2017, In : Leukemia. 31, 5, p. 1048-1058 11 p.

Research output: Contribution to journalArticleScientificpeer-review

NK cell dynamics and association with molecular response in early chronic phase chronic myelogenous leukemia (CML-CP) patients treated with nilotinib

Sopper, S., Mustjoki, S., Gjertsen, B. T., Giles, F., Hochhaus, A., Janssen, J. J. W. M., Porkka, K. & Wolf, D., Oct 2017, In : Leukemia. 31, 10, p. 2264-2267 5 p.

Research output: Contribution to journalArticleScientific

Reduced CD62L Expression on T Cells and Increased Soluble CD62L Levels Predict Molecular Response to Tyrosine Kinase Inhibitor Therapy in Early Chronic-Phase Chronic Myelogenous Leukemia

Sopper, S., Mustjoki, S., White, D., Hughes, T., Valent, P., Burchert, A., Gjertsen, B. T., Gastl, G., Baldauf, M., Trajanoski, Z., Giles, F., Hochhaus, A., Ernst, T., Schenk, T., Janssen, J. J. W. M., Ossenkoppele, G. J., Porkka, K. & Wolf, D., 10 Jan 2017, In : Journal of Clinical Oncology. 35, 2, p. 175-+ 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Single cell immune profiling by mass cytometry of newly diagnosed chronic phase chronic myeloid leukemia treated with nilotinib

Gullaksen, S-E., Skavland, J., Gavasso, S., Tosevski, V., Warzocha, K., Dumrese, C., Ferrant, A., Gedde-Dahl, T., Hellmann, A., Janssen, J., Labar, B., Lang, A., Majeed, W., Mihaylov, G., Stentoft, J., Stenke, L., Thaler, J., Thielen, N., Verhoef, G., Voglova, J. & 9 othersOssenkoppele, G., Hochhaus, A., Hjorth-Hansen, H., Mustjoki, S., Sopper, S., Giles, F., Porkka, K., Wolf, D. & Gjertsen, B. T., Aug 2017, In : Haematologica. 102, 8, p. 1361-1367 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Somatic mutations in clonally expanded cytotoxic T lymphocytes in patients with newly diagnosed rheumatoid arthritis

Savola, P., Kelkka, T., Rajala, H. L., Kuuliala, A., Kuuliala, K., Eldfors, S., Ellonen, P., Lagstrom, S., Lepisto, M., Hannunen, T., Andersson, E. I., Khajuria, R. K., Jaatinen, T., Koivuniemi, R., Repo, H., Saarela, J., Porkka, K., Leirisalo-Repo, M. & Mustjoki, S., 21 Jun 2017, In : Nature Communications. 8, 14 p., 15869.

Research output: Contribution to journalArticleScientificpeer-review

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2016

Assessment of bone marrow lymphocytic status during tyrosine kinase inhibitor therapy and its relation to therapy response in chronic myeloid leukaemia

El Missiry, M., Awad, S. A., Koskela, H. L. M., Al-Samadi, A., Ekblom, M., Markevan, B., Astrand-Grundstrom, I., Wold, M., Svedahl, E. R., Juhl, B. R., Bjerrum, O. W., Haulin, I., Porkka, K., Olsson-Stromberg, U., Hjorth-Hansen, H. & Mustjoki, S., May 2016, In : Journal of Cancer Research and Clinical Oncology. 142, 5, p. 1041-1050 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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ASSESSMENT OF THERAPY RESPONSE IN CHRONIC MYELOID LEUKEMIA VIA 1 MONTH BCR-ABL1 TRANSCRIPT DECLINE

El Missiry, M., Hjorth-hansen, H., Richter, J., Olson-Stromberg, U., Stenke, L., Porkka, K., Kreutzmann, A. & Mustjoki, S., Jun 2016, In : Haematologica. 101, p. 63-63 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Cessation of Tyrosine Kinase Inhibitors Treatment in Chronic Myeloid Leukemia Patients with Deep Molecular Response: Results of the Euro-Ski Trial

Mahon, F., Richter, J., Guilhot, J., Hjorth-Hansen, H., Almeida, A., Janssen, J. J. W. M., Mayer, J., Porkka, K., Panayiotidis, P., Stromberg, U., Berger, M. G., Diamond, J., Ehrencrona, H., Kairisto, V., Polakova, K. M., Mueller, M. C., Mustjoki, S., Hochhaus, A., Pfirrmann, M. & Saussele, S., 2 Dec 2016, In : Blood. 128, 22, 4 p., 787 .

Research output: Contribution to journalMeeting AbstractResearchpeer-review

CML Patients with Primary Resistance or Suboptimal Response to TKI Therapy Have Variants in Genes Affecting Drug Absorption and Metabolism

Pietarinen, P., Koskenvesa, P., Klievink, J., Porkka, K., Niemi, M. & Mustjoki, S., 2 Dec 2016, In : Blood. 128, 22, 4 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Deregulated CD62L expression predicts molecular response to nilotinib therapy in early chronic phase Chronic Myelogenous Leukemia (CML-CP)

Wolf, D., Mustjoki, S., Gjertsen, B. -T., Gastl, G., Baldauf, M., Trajanoski, Z., Giles, F., Hochhaus, A., Ernst, T., Schenk, T., Janssen, J., Porkka, K. & Sopper, S., Oct 2016, In : Oncology research and treatment. 39, p. 39-39 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Design of the randomized, Phase III, QUAZAR AML Maintenance trial of CC-486 (oral azacitidine) maintenance therapy in acute myeloid leukemia

Roboz, G. J., Montesinos, P., Selleslag, D., Wei, A., Jang, J-H., Falantes, J., Voso, M. T., Sayar, H., Porkka, K., Marlton, P., Almeida, A., Mohan, S., Ravandi, F., Garcia-Manero, G., Skikne, B. & Kantarjian, H., 2016, In : Future Oncology. 12, 3, p. 293-302 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Early MRD-Negativity May Predict for Favorable Outcome Irrespective of Allotransplantation in TKI-Treated Patients with Ph-Positive Acute Lymphoblastic Leukemia

Hohtari, H., Sinisalo, M., Nousiainen, T., Koskenvesa, P., Wartiovaara-Kautto, U., Mustjoki, S., Koistinen, P., Saeily, M., Itaelae-Remes, M., Elonen, E., Remes, K. & Porkka, K., 2 Dec 2016, In : Blood. 128, 22, 5 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Effects of Dasatinib and Interferon-alpha Combination Treatment on the Immune System in CML

Ilander, M., Lahteenmaki, H., Olsson-Stromberg, U., Stentoft, J., Richter, J., Koskenvesa, P., Hoglund, M., Dreimane, A., Porkka, K., Gedde-Dahl, T., Gjertsen, B. T., Gruber, F. X., Stenke, L., Myhr-Eriksson, K., Markevarn, B., Lubking, A., Vestergaard, H., Udby, L., Bjerrum, O. W., Hjorth-Hansen, H. & 1 othersMustjoki, S., 2 Dec 2016, In : Blood. 128, 22, 5 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Enrichment of rare variants in population isolates: single AICDA mutation responsible for hyper-IgM syndrome type 2 in Finland

Trotta, L., Hautala, T., Hamalainen, S., Syrjanen, J., Viskari, H., Almusa, H., Lepisto, M., Kaustio, M., Porkka, K., Palotie, A., Seppanen, M. & Saarela, J., Oct 2016, In : European Journal of Human Genetics. 24, 10, p. 1473-1478 6 p.

Research output: Contribution to journalArticleScientificpeer-review

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European LeukemiaNet recommendations for the management and avoidance of adverse events of treatment in chronic myeloid leukaemia

Steegmann, J. L., Baccarani, M., Breccia, M., Casado, L. F., Garcia-Gutierrez, V., Hochhaus, A., Kim, D-W., Kim, T. D., Khoury, H. J., Le Coutre, P., Mayer, J., Milojkovic, D., Porkka, K., Rea, D., Rosti, G., Saussele, S., Hehlmann, R. & Clark, R. E., Aug 2016, In : Leukemia. 30, 8, p. 1648-1671 24 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

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Frontline nilotinib in patients with chronic myeloid leukemia in chronic phase: results from the European ENEST1st study

Hochhaus, A., Rosti, G., Cross, N. C. P., Steegmann, J. L., le Coutre, P., Ossenkoppele, G., Petrov, L., Masszi, T., Hellmann, A., Griskevicius, L., Wiktor-Jedrzejczak, W., Rea, D., Coriu, D., Bruemmendorf, T. H., Porkka, K., Saglio, G., Gastl, G., Mueller, M. C., Schuld, P., Di Matteo, P. & 5 othersPellegrino, A., Dezzani, L., Mahon, F-X., Baccarani, M. & Giles, F. J., Jan 2016, In : Leukemia. 30, 1, p. 57-64 8 p.

Research output: Contribution to journalArticleScientificpeer-review

IL1RAP antibodies block IL-1-induced expansion of candidate CML stem cells and mediate cell killing in xenograft models

Agerstam, H., Hansen, N., von Palffy, S., Sanden, C., Reckzeh, K., Karlsson, C., Lilljebjorn, H., Landberg, N., Askmyr, M., Hogberg, C., Rissler, M., Porkka, K., Wadenvik, H., Mustjoki, S., Richter, J., Jaras, M. & Fioretos, T., 8 Dec 2016, In : Blood. 128, 23, p. 2683-2693 11 p.

Research output: Contribution to journalArticleScientificpeer-review

IL1RAP Antibodies Block IL1-Induced Expansion of Primitive CML Cells and Display Therapeutic Effects in Xenograft Models

Agerstam, H., Hansen, N., Von Palffy, S., Sanden, C., Reckzeh, K., Karlsson, C., Lilljebjorn, H., Landberg, N., Askmyr, M., Hogberg, C., Rissler, M., Porkka, K., Wadenvik, H., Mustjoki, S., Richter, J., Jaras, M. & Fioretos, T., 2 Dec 2016, In : Blood. 128, 22, 4 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Impact of starting material and expansion conditions on cell yield and composition of CAR T cell products

Kaartinen, T., Luostarinen, A., Belt, H., Koponen, J., Nousiainen, A., Mäkinen, P., Yla-Herttuala, S., Mustjoki, S., Porkka, K. & Korhonen, M., May 2016, In : Scandinavian Journal of Immunology. 83, 5, p. 374-374 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Intrinsic resistance to PIM kinase inhibition in AML through p38a-mediated feedback activation of mTOR signaling

Brunen, D., Jose Garcia-Barchino, M., Malani, D., Basheer, N. J., Lieftink, C., Beijersbergen, R. L., Murumagi, A., Porkka, K., Wolf, M., Zwaan, C. M., Fornerod, M., Kallioniemi, O., Angel Martinez-Climent, J. & Bernards, R., 21 Jun 2016, In : Oncotarget. 7, 25, p. 37407-37419 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Leukemic Stem Cell Quantification in Newly Diagnosed Patients With Chronic Myeloid Leukemia Predicts Response to Nilotinib Therapy

Thielen, N., Richter, J., Baldauf, M., Barbany, G., Fioretos, T., Giles, F., Gjertsen, B-T., Hochhaus, A., Schuurhuis, G. J., Sopper, S., Stenke, L., Thunberg, S., Wolf, D., Ossenkoppele, G., Porkka, K., Janssen, J. & Mustjoki, S., 15 Aug 2016, In : Clinical Cancer Research. 22, 16, p. 4030-4038 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Lymphocytosis after treatment with dasatinib in chronic myeloid leukemia: Effects on response and toxicity

Schiffer, C. A., Cortes, J. E., Hochhaus, A., Saglio, G., le Coutre, P., Porkka, K., Mustjoki, S., Mohamed, H. & Shah, N. P., 1 May 2016, In : Cancer. 122, 9, p. 1398-1407 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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