Kimmo Porkka

Publications

Research Output per year

1995 2020

• 117 Article
• 23 Meeting Abstract
• 7 Review Article
• 6 Chapter
• 10 More
  • 3 Abstract
  • 3 Letter
  • 2 Conference article
  • 1 Anthology or special issue
  • 1 Patent

Research Output per year

Research Output per year

Search results

• 2020

  Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia

  DiNardo, C. D., Jonas, B. A., Pullarkat, V., Thirman, M. J., Garcia, J. S., Wei, A. H., Konopleva, M., Doehner, H., Letai, A., Fenaux, P., Koller, E., Havelange, V., Leber, B., Esteve, J., Wang, J., Pejsa, V., Hajek, R., Porkka, K., Illes, A., Lavie, D. & 10 others, Lemoli, R. M., Yamamoto, K., Yoon, S. -S., Jang, J. -H., Yeh, S. -P., Turgut, M., Hong, W. -J., Zhou, Y., Potluri, J. & Pratz, K. W., 13 Aug 2020, In : New England Journal of Medicine. 383, 7, p. 617-629 13 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Characterization of p190-Bcr-Abl chronic myeloid leukemia reveals specific signaling pathways and therapeutic targets

  Adnan-Awad, S., Kim, D., Hohtari, H., Javarappa, K. K., Brandstoetter, T., Mayer, I., Potdar, S., Heckman, C. A., Kytölä, S., Porkka, K., Doma, E., Sexl, V., Kankainen, M. & Mustjoki, S., 9 Nov 2020, In : Leukemia. 12 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

• EHA evaluation of the ESMO-Magnitude of Clinical Benefit Scale version 1.1 (ESMO-MCBS v1.1) for haematological malignancies

  Kiesewetter, B., Cherny, N. I., Boissel, N., Cerisoli, F., Dafni, U., de Vries, E. G. E., Ghia, P., Goekbuget, N., Gonzalez-Calle, V., Huntly, B., Jaeger, U., Latino, N. J., Douillard, J-Y., Malcovati, L., Mateos, M-V., Ossenkoppele, G. J., Porkka, K., Raderer, M., Ribera, J-M., Scarfo, L. & 3 others, Wester, R., Zygoura, P. & Sonneveld, P., Jan 2020, In : ESMO open. 5, 1, 18 p., 000611.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Immune profiles in acute myeloid leukemia bone marrow associate with patient age, T-cell receptor clonality, and survival

  Brück, O., Dufva, O., Hohtari, H., Blom, S., Turkki, R., Ilander, M., Kovanen, P., Pallaud, C., Ramos, P. M., Lähteenmäki, H., Välimäki, K., El Missiry, M., Ribeiro, A., Kallioniemi, O., Porkka, K., Pellinen, T. & Mustjoki, S., 28 Jan 2020, In : Blood advances. 4, 2, p. 274-286 13 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Integration of Deep Multi-Omics Profiling Veals New Insights into the Biology of Poor-Risk Acute Myeloid Leukemia

  Rio-Machin, A., Casado-Izquierdo, P., Miettinen, J., Bewicke-Copley, F., Khan, N., Demeulemeester, J., Krizsán, S., Zheng, J., Middleton, C., Yin, W., Grey, W., Miraki-Moud, F., Matthews, J., Grantham, M., Rouault-Pierre, K., Wennerberg, K., Parsons, A. O., Armes, H., Close, K. EM., Di Bella, D. & 12 others, Cavenagh, J., Freeman, S. D., Van Loo, P., Bödör, C., Porkka, K., Heckman, C., Wang, J., Taussig, D., Bonnet, D., Cazier, J-B., Cutillas, P. R. & Fitzgibbon, J., 5 Nov 2020, p. 39-40. 1 p.

  Research output: Conference materials › Abstract › peer-review

• KIT pathway upregulation predicts dasatinib efficacy in acute myeloid leukemia

  Malani, D., Yadav, B., Kumar, A., Potdar, S., Kontro, M., Kankainen, M., Javarappa, K. K., Porkka, K., Wolf, M., Aittokallio, T., Wennerberg, K., Heckman, C. A., Murumägi, A. & Kallioniemi, O., 17 Jul 2020, In : Leukemia. 34, 10, p. 2780–2784 4 p., 34.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Multi-parametric single cell evaluation defines distinct drug responses in healthy hematologic cells that are retained in corresponding malignant cell types

  Majumder, M. M., Leppä, A-M., Hellesøy, M., Dowling, P., Malyutina, A., Kopperud, R., Bazou, D., Andersson, E., Parsons, A., Tang, J., Kallioniemi, O., Mustjoki, S., O´Gorman, P., Wennerberg, K., Porkka, K., Gjertsen, B. T. & Heckman, C. A., Jun 2020, In : Haematologica. 105, 6, p. 1527-1538 12 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Mutation accumulation in cancer genes relates to nonoptimal outcome in chronic myeloid leukemia

  Awad, S. A., Kankainen, M., Ojala, T., Koskenvesa, P., Eldfors, S., Ghimire, B., Kumar, A., Kytölä, S., Kamel, M. M., Heckman, C. A., Porkka, K. & Mustjoki, S., 11 Feb 2020, In : Blood advances. 4, 3, p. 546-559 14 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Pan-RAF inhibition induces apoptosis in acute myeloid leukemia cells and synergizes with BCL2 inhibition

  Tambe, M., Karjalainen, E., Vähä-Koskela, M., Bulanova, D., Gjertsen, B. T., Kontro, M., Porkka, K., Heckman, C. A. & Wennerberg, K., 10 Jul 2020, In : Leukemia. 11 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Phase 1 study of the protein deubiquitinase inhibitor VLX1570 in patients with relapsed and/or refractory multiple myeloma

  Rowinsky, E. K., Paner, A., Berdeja, J. G., Paba-Prada, C., Venugopal, P., Porkka, K., Gullbo, J., Linder, S., Loskog, A., Richardson, P. G. & Landgren, O., Oct 2020, In : Investigational New Drugs. 38, 5, p. 1448-1453 6 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia

  Kuusanmäki, H., Leppä, A-M., Pölönen, P., Kontro, M., Dufva, O., Deb, D., Yadav, B., Bruck, O., Kumar, A., Everaus, H., Gjertsen, B. T., Heinäniemi, M., Porkka, K., Mustjoki, S. & Heckman, C. A., 1 Mar 2020, In : Haematologica. 105, 3, p. 708-720 13 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• RUNX1mutations in blast-phase chronic myeloid leukemia associate with distinct phenotypes, transcriptional profiles, and drug responses

  Awad, S. A., Dufva, O., Ianevski, A., Ghimire, B., Koski, J., Maliniemi, P., Thomson, D., Schreiber, A., Heckman, C. A., Koskenvesa, P., Korhonen, M., Porkka, K., Branford, S., Aittokallio, T., Kankainen, M. & Mustjoki, S., 11 Aug 2020, In : Leukemia. 13 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2019

  Acute Lymphoblastic Leukemia With INPP5D-ABL1 Fusion Responds to Imatinib Treatment

  Poukka, M., Lund-Aho, T., Raittinen, P., Nikkilä, A., Kivinen, K., Lundan, T., Porkka, K. & Lohi, O., Oct 2019, In : Journal of pediatric hematology/oncology. 41, 7, p. E481-E483 3 p.

  Research output: Contribution to journal › Article › Scientific

• Consensus criteria for diagnosis, staging, and treatment response assessment of T-cell prolymphocytic leukemia

  Staber, P. B., Herling, M., Bellido, M., Jacobsen, E. D., Davids, M. S., Kadia, T. M., Shustov, A., Tournilhac, O., Bachy, E., Zaja, F., Porkka, K., Hoermann, G., Simonitsch-Klupp, I., Haferlach, C., Kubicek, S., Mayerhoefer, M. E., Hopfinger, G., Jaeger, U. & Dearden, C., 3 Oct 2019, In : Blood. 134, 14, p. 1132-1143 12 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Dasatinib and navitoclax act synergistically to target NUP98-NSD1(+)/FLT3-ITD+ acute myeloid leukemia

  Kivioja, J. L., Thanasopoulou, A., Kumar, A., Kontro, M., Yadav, B., Majumder, M. M., Javarappa, K. K., Eldfors, S., Schwaller, J., Porkka, K. & Heckman, C. A., Jun 2019, In : Leukemia. 33, 6, p. 1360-1372 13 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Elevated expression of S100A8 and S100A9 correlates with resistance to the BCL-2 inhibitor venetoclax in AML

  Karjalainen, R., Liu, M., Kumar, A., Malani, D., Parsons, A., Kontro, M., Kallioniemi, O., Porkka, K. & Heckman, C., Oct 2019, In : Leukemia. 33, 10, p. 2548-2553 6 p.

  Research output: Contribution to journal › Letter › Scientific

• ERCC6L2 defines a novel entity within inherited acute myeloid leukemia

  Douglas, S. P. M., Siipola, P., Kovanen, P. E., Pyörälä, M., Kakko, S., Savolainen, E-R., Salmenniemi, U., Orte, K., Kytölä, S., Pitkänen, E., Porkka, K., Kilpivaara, O. & Wartiovaara-Kautto, U., 20 Jun 2019, In : Blood. 133, 25, p. 2724-2728 7 p.

  Research output: Contribution to journal › Letter › Scientific

• Hemap: An Interactive Online Resource for Characterizing Molecular Phenotypes across Hematologic Malignancies

  Pölönen, P., Mehtonen, J., Lin, J., Liuksiala, T., Häyrynen, S., Teppo, S., Mäkinen, A., Kumar, A., Malani, D., Pohjolainen, V., Porkka, K., Heckman, C. A., May, P., Hautamäki, V., Granberg, K. J., Lohi, O., Nykter, M. & Heinäniemi, M., 15 May 2019, In : Cancer Research. 79, 10, p. 2466-2479 14 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Immune cell constitution in bone marrow microenvironment predicts outcome in adult ALL

  Hohtari, H., Bruck, O., Blom, S., Turkki, R., Sinisalo, M., Kovanen, P. E., Kallioniemi, O., Pellinen, T., Porkka, K. & Mustjoki, S., Jul 2019, In : Leukemia. 33, 7, p. 1570-1582 13 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Kliininen hematologia - tietolaatikko

  Tarkkanen, M., Porkka, K. & Rapola, R., 2019, In : Duodecim. 135, 12, p. 1208-1208 1 p.

  Research output: Contribution to journal › Article › Professional

  Open Access

  File

• Kuka päättää hoidosta - lääkäri, potilas, tekoäly vai taloushallinto?

  Porkka, K., 2019, In : Sic! Lääketietoa Fimeasta. 9, 3-4, p. 19-21 3 p.

  Research output: Contribution to journal › Article › Professional

• Lääkärin syntymäpäiviä vietetään useammin alkuvuodesta

  Alenius, S., Saxén, H., Porkka, K., Nurhonen, M. & Kajantie, E., 2019, In : Duodecim. 135, 24, p. 2428-2434 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2018

  Case studies investigating genetic heterogeneity between anatomically distinct bone marrow compartments in acute myeloid leukemia

  Ojamies, P. N., Kontro, M., Edgren, H., Ellonen, P., Heckman, C., Porkka, K., Wolf, M. & Kallioniemi, O., 2 Dec 2018, In : Leukemia & lymphoma. 59, 12, p. 3002-3005 4 p.

  Research output: Contribution to journal › Letter › Scientific › peer-review

• Chimeric NUP98-NSD1 transcripts from the cryptic t(5;11)(q35.2;p15.4) in adult de novo acute myeloid leukemia

  Kivioja, J., Lopez Marti, J. M., Kumar, A., Kontro, M., Edgren, H., Parsons, A., Lundan, T., Wolf, M., Porkka, K. & Heckman, C., 2018, In : Leukemia & lymphoma. 59, 3, p. 725-732 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Combined Targeting of BET Family Proteins and BCL2 Is Synergistic in Acute Myeloid Leukemia Cells Overexpressing S100A8 and S100A9

  Karjalainen, R., Liu, M., Kumar, A., Parsons, A., He, L., Malani, D. R., Kontro, M., Porkka, K. & Heckman, C. A., 2018, In : Blood. 132

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

• Germline alterations in a consecutive series of acute myeloid leukemia

  Wartiovaara-Kautto, U., Hirvonen, E. A. M., Pitkänen, E., Heckman, C., Saarela, J., Kettunen, K., Porkka, K. & Kilpivaara, O., Oct 2018, In : Leukemia. 32, 10, p. 2282-2285 4 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

• Immune cell contexture in the bone marrow tumor microenvironment impacts therapy response in CML

  Bruck, O., Blom, S., Dufva, O., Turkki, R., Chheda, H., Ribeiro, A., Kovanen, P., Aittokallio, T., Koskenvesa, P., Kallioniemi, O., Porkka, K., Pellinen, T. & Mustjoki, S., Jul 2018, In : Leukemia. 32, 7, p. 1643-1656 14 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Multi-Parametric Single Cell Profiling Defines Distinct Drug Responses in Healthy Hematological Cell Lineages That Are Retained in Corresponding Malignant Cell Types

  Majumder, MM., Leppä, A-M., Hellesøy, M., Dowling, P., Malyutina, A., Bazou, D., Andersson, E. I., Parsons, A., Tang, J., Kallioniemi, O-P., Mustjoki, S. M., O'Gorman, P., Wennerberg, J. K., Porkka, K. V. K., Gjertsen, B-T. & Heckman, C. A., 2018, In : Blood. 132

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

• Quantitative Multiplex Immunohistochemistry Identifies Immunosuppression in the AML Bone Marrow and NK-Cells As Prognostic Biomarker in Intermediate-Risk Patients

  Bruck, O., Dufva, O., Blom, S., Turkki, R., Ilander, M., Siitonen, S. M., Kovanen, P., Pallaud, C., Ramos, P. M., Lahteenmaki, H., Valimaki, K., Ribeiro, A., Kallioniemi, O., Porkka, K., Pellinen, T. & Mustjoki, S., 29 Nov 2018, In : Blood. 132, 3 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

• Syövän immunologinen täsmähoito geneettisesti muokatuilla T-soluilla

  Korhonen, M., Keränen, M., Vettenranta, K., Leppä, S., Ylä-Herttuala, S. & Porkka, K., 2018, In : Duodecim. 134, 16, p. 1592-1599 8 p.

  Research output: Contribution to journal › Review Article › peer-review

  Open Access

  File

• Targeting BCL-2, BCL-XL, BCL-W and MDM2 in B-Cell Acute Lymphoblastic Leukemia Is Highly Effective Ex Vivo

  Hohtari, H., Adnan Awad, S., Dufva, O., Potdar, S., Heckman, C., Wennerberg, K., Mustjoki, S. & Porkka, K., 2018.

  Research output: Conference materials › Abstract › peer-review

  Open Access
• 2017

  Dasatinib Changes Immune Cell Profiles Concomitant with Reduced Tumor Growth in Several Murine Solid Tumor Models

  Hekim, C., Ilander, M., Yan, J., Michaud, E., Smykla, R., Vaha-Koskela, M., Savola, P., Tahtinen, S., Saikko, L., Hemminki, A., Kovanen, P. E., Porkka, K., Lee, F. Y. F. & Mustjoki, S., Feb 2017, In : Cancer immunology research. 5, 2, p. 157-169 13 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

• Differentiation status of primary chronic myeloid leukemia cells affects sensitivity to BCR-ABL1 inhibitors

  Pietarinen, P. O., Eide, C. A., Ayuda-Duran, P., Potdar, S., Kuusanmaki, H., Andersson, E. I., Mpindi, J. P., Pemovska, T., Kontro, M., Heckman, C. A., Kallioniemi, O., Wennerberg, K., Hjorth-Hansen, H., Druker, B. J., Enserink, J. M., Tyner, J. W., Mustjoki, S. & Porkka, K., 4 Apr 2017, In : Oncotarget. 8, 14, p. 22606-22615 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Early BCR-ABL1 Transcript Decline after 1 Month of Tyrosine Kinase Inhibitor Therapy as an Indicator for Treatment Response in Chronic Myeloid Leukemia

  El Missiry, M., Hjorth-Hansen, H., Richter, J., Olson-Stromberg, U., Stenke, L., Porkka, K., Kreutzman, A. & Mustjoki, S., 30 Jan 2017, In : PLoS One. 12, 1, 17 p., 0171041.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML

  Malani, D., Murumagi, A., Yadav, B., Kontro, M., Eldfors, S., Kumar, A., Karjalainen, R., Majumder, M. M., Ojamies, P., Pemovska, T., Wennerberg, K., Heckman, C., Porkka, K., Wolf, M., Aittokallio, T. & Kallioniemi, O., May 2017, In : Leukemia. 31, 5, p. 1187-1195 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Genomilääketieteen sovelluksia sairauksien hoidossa

  Porkka, K., Niemi, M., Leppä, E., Västrik, I., Partanen, J., Ihalainen, J., Jokiranta, S. & Pöllänen, P., 2017, In : Duodecim. 133, 8, p. 782-790 9 p.

  Research output: Contribution to journal › Article › Professional

  Open Access

  File

• High Amount of PD1+TIM3+ T Helper Cells May Predict Poor Outcome in Adult Acute Lymphoblastic Leukemia

  Hohtari, H., Bruck, O., Blom, S., Turkki, R., Ribeiro, A., Sinisalo, M., Kovanen, P., Kallioniemi, O., Pellinen, T., Porkka, K. & Mustjoki, S., 2017, p. 3985. 1 p.

  Research output: Conference materials › Abstract › peer-review

• HOX gene expression predicts response to BCL-2 inhibition in acute myeloid leukemia

  Kontro, M., Kumar, A., Majumder, M. M., Eldfors, S., Parsons, A., Pemovska, T., Saarela, J. S., Yadav, B., Malani, D. R., Fløisand, Y., Höglund, M., Remes, K., Gjertsen, B-T., Kallioniemi, O-P., Wennerberg, J. K., Heckman, C. A. & Porkka, K. V. K., 2017, In : Leukemia. 31, 2, p. 301-309 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  File

• Idelalisib sensitivity and mechanisms of disease progression in relapsed TCF3-PBX1 acute lymphoblastic leukemia

  Eldfors, S., Kuusanmäki, H., Kontro, M., Majumder, M. M., Parsons, A., Edgren, H., Pemovska, T., Kallioniemi, O., Wennerberg, K., Gökbuget, N., Burmeister, T., Porkka, K. & Heckman, C. A., 2017, In : Leukemia. 31, 1, p. 51-57 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Identification of precision treatment strategies for relapsed/refractory multiple myeloma by functional drug sensitivity testing

  Majumder, M. M., Silvennoinen, R., Anttila, P., Tamborero, D., Eldfors, S., Yadav, B., Karjalainen, R., Kuusanmaki, H., Lievonen, J., Parsons, A., Suvela, M., Jantunen, E., Porkka, K. & Heckman, C. A., 22 Aug 2017, In : Oncotarget. 8, 34, p. 56338-56350 13 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• IMMUNOLOGICAL CHARACTERIZATION OF PH plus ALL BONE MARROW BY MULTIPLEX IMMUNOHISTOCHEMISTRY

  Hohtari, H., Bruck, O., Blom, S., Turkki, R., Ribeiro, A., Sinisalo, M., Kovanen, P., Kallioniemi, O., Pellinen, T., Porkka, K. & Mustjoki, S., 26 Jun 2017, In : Haematologica. 102, p. 654-654 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

• Increased proportion of mature NK cells is associated with successful imatinib discontinuation in chronic myeloid leukemia

  Ilander, M., Olsson-Stromberg, U., Schlums, H., Guilhot, J., Bruck, O., Lahteenmaki, H., Kasanen, T., Koskenvesa, P., Soderlund, S., Hoglund, M., Markevarn, B., Sjalander, A., Lotfi, K., Dreimane, A., Lubking, A., Holm, E., Bjoreman, M., Lehmann, S., Stenke, L., Ohm, L. & 11 others, Gedde-Dahl, T., Majeed, W., Ehrencrona, H., Koskela, S., Saussele, S., Mahon, F-X., Porkka, K., Hjorth-Hansen, H., Bryceson, Y. T., Richter, J. & Mustjoki, S., May 2017, In : Leukemia. 31, 5, p. 1108-1116 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

• JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell-induced protection of AML

  Karjalainen, R., Pemovska, T., Popa, M., Liu, M., Javarappa, K. K., Majumder, M. M., Yadav, B., Tamborero, D., Tang, J., Bychkov, D., Kontro, M., Parsons, A., Suvela, M., Safont, M. M., Porkka, K., Aittokallio, T., Kallioniemi, O., McCormack, E., Gjertsen, B. T., Wennerberg, K. & 2 others, Knowles, J. & Heckman, C. A., 10 Aug 2017, In : Blood. 130, 6, p. 789-802 14 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

• LOW IL-2 CONCENTRATION FAVORS GENERATION OF EARLY MEMORY T CELLS OVER TERMINAL EEFECTORS DURING CAR T-CELL EXPANSION

  Luostarinen, A., Kaartinen, T., Maliniernii, P., Keto, J., Arvas, M., Belt, H., Koponen, J., Loskog, A., Mustjoki, S., Porkka, K., Yla-Herttuala, S. & Korhonen, M., May 2017, In : Cytotherapy. 19, 5, p. S8-S8 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

• Low interleukin-2 concentration favors generation of early memory T cells over effector phenotypes during chimeric antigen receptor T-cell expansion

  Kaartinen, T., Luostarinen, A., Maliniemi, P., Keto, J., Arvas, M., Belt, H., Koponen, J., Loskog, A., Mustjoki, S., Porkka, K., Yla-Herttuala, S. & Korhonen, M., Jun 2017, In : Cytotherapy. 19, 6, p. 689-702 14 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Monitoring therapy responses at the leukemic subclone level by ultra-deep amplicon resequencing in acute myeloid leukemia

  Ojamies, P., Kontro, M., Edgren, H., Ellonen, P., Lagström, S., Almusa, H., Miettinen, T., Eldfors, S., Tamborero, D., Wennerberg, K., Heckman, C., Porkka, K., Wolf, M. & Kallioniemi, O., 2017, In : Leukemia. 31, 5, p. 1048-1058 11 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• NK cell dynamics and association with molecular response in early chronic phase chronic myelogenous leukemia (CML-CP) patients treated with nilotinib

  Sopper, S., Mustjoki, S., Gjertsen, B. T., Giles, F., Hochhaus, A., Janssen, J. J. W. M., Porkka, K. & Wolf, D., Oct 2017, In : Leukemia. 31, 10, p. 2264-2267 5 p.

  Research output: Contribution to journal › Article › Scientific

• Reduced CD62L Expression on T Cells and Increased Soluble CD62L Levels Predict Molecular Response to Tyrosine Kinase Inhibitor Therapy in Early Chronic-Phase Chronic Myelogenous Leukemia

  Sopper, S., Mustjoki, S., White, D., Hughes, T., Valent, P., Burchert, A., Gjertsen, B. T., Gastl, G., Baldauf, M., Trajanoski, Z., Giles, F., Hochhaus, A., Ernst, T., Schenk, T., Janssen, J. J. W. M., Ossenkoppele, G. J., Porkka, K. & Wolf, D., 10 Jan 2017, In : Journal of Clinical Oncology. 35, 2, p. 175-+ 14 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Single cell immune profiling by mass cytometry of newly diagnosed chronic phase chronic myeloid leukemia treated with nilotinib

  Gullaksen, S-E., Skavland, J., Gavasso, S., Tosevski, V., Warzocha, K., Dumrese, C., Ferrant, A., Gedde-Dahl, T., Hellmann, A., Janssen, J., Labar, B., Lang, A., Majeed, W., Mihaylov, G., Stentoft, J., Stenke, L., Thaler, J., Thielen, N., Verhoef, G., Voglova, J. & 9 others, Ossenkoppele, G., Hochhaus, A., Hjorth-Hansen, H., Mustjoki, S., Sopper, S., Giles, F., Porkka, K., Wolf, D. & Gjertsen, B. T., Aug 2017, In : Haematologica. 102, 8, p. 1361-1367 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Somatic mutations in clonally expanded cytotoxic T lymphocytes in patients with newly diagnosed rheumatoid arthritis

  Savola, P., Kelkka, T., Rajala, H. L., Kuuliala, A., Kuuliala, K., Eldfors, S., Ellonen, P., Lagstrom, S., Lepisto, M., Hannunen, T., Andersson, E. I., Khajuria, R. K., Jaatinen, T., Koivuniemi, R., Repo, H., Saarela, J., Porkka, K., Leirisalo-Repo, M. & Mustjoki, S., 21 Jun 2017, In : Nature Communications. 8, 14 p., 15869.

  Research output: Contribution to journal › Article › Scientific › peer-review

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