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Publications 1995 2019

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Meeting Abstract
2018

Combined Targeting of BET Family Proteins and BCL2 Is Synergistic in Acute Myeloid Leukemia Cells Overexpressing S100A8 and S100A9

Karjalainen, R., Liu, M., Kumar, A., Parsons, A., He, L., Malani, D. R., Kontro, M., Porkka, K. & Heckman, C. A., 2018, In : Blood. 132

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access

Multi-Parametric Single Cell Profiling Defines Distinct Drug Responses in Healthy Hematological Cell Lineages That Are Retained in Corresponding Malignant Cell Types

Majumder, MM., Leppä, A-M., Hellesøy, M., Dowling, P., Malyutina, A., Bazou, D., Andersson, E. I., Parsons, A., Tang, J., Kallioniemi, O-P., Mustjoki, S. M., O'Gorman, P., Wennerberg, J. K., Porkka, K. V. K., Gjertsen, B-T. & Heckman, C. A., 2018, In : Blood. 132

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Open Access
2017

IMMUNOLOGICAL CHARACTERIZATION OF PH plus ALL BONE MARROW BY MULTIPLEX IMMUNOHISTOCHEMISTRY

Hohtari, H., Bruck, O., Blom, S., Turkki, R., Ribeiro, A., Sinisalo, M., Kovanen, P., Kallioniemi, O., Pellinen, T., Porkka, K. & Mustjoki, S., 26 Jun 2017, In : Haematologica. 102, p. 654-654 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

LOW IL-2 CONCENTRATION FAVORS GENERATION OF EARLY MEMORY T CELLS OVER TERMINAL EEFECTORS DURING CAR T-CELL EXPANSION

Luostarinen, A., Kaartinen, T., Maliniernii, P., Keto, J., Arvas, M., Belt, H., Koponen, J., Loskog, A., Mustjoki, S., Porkka, K., Yla-Herttuala, S. & Korhonen, M., May 2017, In : Cytotherapy. 19, 5, p. S8-S8 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2016

ASSESSMENT OF THERAPY RESPONSE IN CHRONIC MYELOID LEUKEMIA VIA 1 MONTH BCR-ABL1 TRANSCRIPT DECLINE

El Missiry, M., Hjorth-hansen, H., Richter, J., Olson-Stromberg, U., Stenke, L., Porkka, K., Kreutzmann, A. & Mustjoki, S., Jun 2016, In : Haematologica. 101, p. 63-63 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Cessation of Tyrosine Kinase Inhibitors Treatment in Chronic Myeloid Leukemia Patients with Deep Molecular Response: Results of the Euro-Ski Trial

Mahon, F., Richter, J., Guilhot, J., Hjorth-Hansen, H., Almeida, A., Janssen, J. J. W. M., Mayer, J., Porkka, K., Panayiotidis, P., Stromberg, U., Berger, M. G., Diamond, J., Ehrencrona, H., Kairisto, V., Polakova, K. M., Mueller, M. C., Mustjoki, S., Hochhaus, A., Pfirrmann, M. & Saussele, S., 2 Dec 2016, In : Blood. 128, 22, 4 p., 787 .

Research output: Contribution to journalMeeting AbstractResearchpeer-review

CML Patients with Primary Resistance or Suboptimal Response to TKI Therapy Have Variants in Genes Affecting Drug Absorption and Metabolism

Pietarinen, P., Koskenvesa, P., Klievink, J., Porkka, K., Niemi, M. & Mustjoki, S., 2 Dec 2016, In : Blood. 128, 22, 4 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Deregulated CD62L expression predicts molecular response to nilotinib therapy in early chronic phase Chronic Myelogenous Leukemia (CML-CP)

Wolf, D., Mustjoki, S., Gjertsen, B. -T., Gastl, G., Baldauf, M., Trajanoski, Z., Giles, F., Hochhaus, A., Ernst, T., Schenk, T., Janssen, J., Porkka, K. & Sopper, S., Oct 2016, In : Oncology research and treatment. 39, p. 39-39 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Early MRD-Negativity May Predict for Favorable Outcome Irrespective of Allotransplantation in TKI-Treated Patients with Ph-Positive Acute Lymphoblastic Leukemia

Hohtari, H., Sinisalo, M., Nousiainen, T., Koskenvesa, P., Wartiovaara-Kautto, U., Mustjoki, S., Koistinen, P., Saeily, M., Itaelae-Remes, M., Elonen, E., Remes, K. & Porkka, K., 2 Dec 2016, In : Blood. 128, 22, 5 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Effects of Dasatinib and Interferon-alpha Combination Treatment on the Immune System in CML

Ilander, M., Lahteenmaki, H., Olsson-Stromberg, U., Stentoft, J., Richter, J., Koskenvesa, P., Hoglund, M., Dreimane, A., Porkka, K., Gedde-Dahl, T., Gjertsen, B. T., Gruber, F. X., Stenke, L., Myhr-Eriksson, K., Markevarn, B., Lubking, A., Vestergaard, H., Udby, L., Bjerrum, O. W., Hjorth-Hansen, H. & 1 othersMustjoki, S., 2 Dec 2016, In : Blood. 128, 22, 5 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

IL1RAP Antibodies Block IL1-Induced Expansion of Primitive CML Cells and Display Therapeutic Effects in Xenograft Models

Agerstam, H., Hansen, N., Von Palffy, S., Sanden, C., Reckzeh, K., Karlsson, C., Lilljebjorn, H., Landberg, N., Askmyr, M., Hogberg, C., Rissler, M., Porkka, K., Wadenvik, H., Mustjoki, S., Richter, J., Jaras, M. & Fioretos, T., 2 Dec 2016, In : Blood. 128, 22, 4 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Impact of starting material and expansion conditions on cell yield and composition of CAR T cell products

Kaartinen, T., Luostarinen, A., Belt, H., Koponen, J., Nousiainen, A., Mäkinen, P., Yla-Herttuala, S., Mustjoki, S., Porkka, K. & Korhonen, M., May 2016, In : Scandinavian Journal of Immunology. 83, 5, p. 374-374 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Lymphoid somatic mutations in multiple sclerosis

Valori, M., Jansson, L., Kiviharju, A., Porkka, K., Ellonen, P., Mustjoki, S. & Tienari, P., Sep 2016, In : Multiple Sclerosis Journal . 22, p. 170-171 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

No Differences in Molecular Relapse-Free Survival after Stopping Imatinib Treatment of Chronic Myeloid Leukemia Between Patients with Prior 4.5 Log Reduction (MR4.5) but Detectable and Patients with Undetectable Disease in the EURO-SKI Trial

Pfirrmann, M., Mahon, F-X., Guilhot, J., Richter, J., Almeida, A., Janssen, J. J. W. M., Mayer, J., Porkka, K., Panayiotidis, P., Olsson-Stromberg, U., Berger, M. G., Diamond, J., Ehrencrona, H., Kairisto, V., Polakova, K. M., Muller, M. C., Mustjoki, S., Hochhaus, A., Saussele, S. & Hjorth-Hansen, H., 2 Dec 2016, In : Blood. 128, 22, 5 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Novel Mutations in Patients with Blast Crisis or Accelerated Phase Chronic Myeloid Leukemia

Awad, S. A., Kankainen, M., Eldfors, S., Kytola, S., Ellonen, P., Kamel, M., Heckman, C. A., Porkka, K. & Mustjoki, S., 2 Dec 2016, In : Blood. 128, 22, 3 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

SOMATIC MUTATIONS IN CLONALLY EXPANDED CD8(+) T CELLS IN PATIENTS WITH NEWLY DIAGNOSED RHEUMATOID ARTHRITIS

Kelkka, T., Savola, P., Rajala, H., Kuuliala, A., Kuuliala, K., Eldfors, S., Ellonen, P., Lagstrom, S., Khajuria, R. K., Jaatinen, T., Koivuniemi, R., Repo, H., Saarela, J., Porkka, K., Leirisalo-Repo, M. & Mustjoki, S., Feb 2016, In : Annals of the Rheumatic Diseases. 75, p. A47-+ 2 p.

Research output: Contribution to journalMeeting AbstractResearch

STOPPING TYROSINE KINASE INHIBITORS IN A VERY LARGE COHORT OF EUROPEAN CHRONIC MYELOID LEUKEMIA PATIENTS: RESULTS OF THE EURO-SKI TRIAL

Richter, J., Mahon, F. X., Guilhot, J., Hjorth-Hansen, H., Almeida, A., Janssen, J. J., Mayer, J., Porkka, K., Panayiotidis, P., Olsson-Stromberg, U., Berger, M. G., Diamond, J., Ehrencrona, H., Kairisto, V., Polakova, K. M., Muller, M. C., Mustjoki, S., Hochhaus, A., Pfirrmann, M. & Saussele, S., Jun 2016, In : Haematologica. 101, p. 22-23 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2013

High-throughput drug screening and molecular profiling for therapeutic targeting of NUP98-NSD1-positive AML

Kontro, M. P., Pemovska, T., Heckman, C. A., Kallioniemi, O-P., Wennerberg, J. K. & Porkka, K. V. K., Feb 2013, In : Annals of Hematology. 92, Supplement 1, p. S18

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2012

Discovery of STAT5b Mutations and Small Subclones of STAT3 Mutations in Large Granular Lymphocytic (LGL) Leukemia

Rajala, H. L. M., Eldfors, S., Kuusanmaki, H., Andersson, E. I., van Adrichem, A. J., Lagstrom, S., Olson, T., Jerez, A., Clemente, M. J., Zhang, D., Awwad, A., Pihlman, M., Ellonen, P., Kallioniemi, O., Wennerberg, K., Porkka, K., Maciejewski, J. P., Loughran, T. P., Heckman, C. A. & Mustjoki, S., 16 Nov 2012, In : Blood. 120, 21, 2 p., Meeting Abstract: 871.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Functional Characterization of T- and NK-Cells in Chronic Myeloid Leukemia Patients Treated with Interferon-alpha Monotherapy.

Ilander, M. M., Kreutzman, A., Rohon, P., Melo, T., Faber, E., Porkka, K., Vakkila, J. & Mustjoki, S., 16 Nov 2012, In : Blood. 120, 21, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Somatic PTPRT and ANGPT2 Mutations in Large Granulocyte Leukemia

Andersson, E. I., Eldfors, S., Koskela, H. L. M., Ellonen, P., Olson, T., Jerez, A., Clemente, M. J., Kallioniemi, O., Porkka, K., Loughran, T. P., Maciejewski, J. P., Heckman, C. & Mustjoki, S., 16 Nov 2012, In : Blood. 120, 21, 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review