Research output per year
Research output per year
- 20 results
Search results
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2024
HiHo-AID2: boosting homozygous knock-in efficiency enables robust generation of human auxin-inducible degron cells
Li, S., Wang, Y., van der Stoel, M., Zhou, X., Madhusudan, S., Kanerva, K., Nguyen, V. D., Eskici, N., Olkkonen, V. M., Zhou, Y., Raivio, T. & Ikonen, E., 2024, In: Genome Biology. 25, 1, 26 p., 58.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2022
Multiparametric platform for profiling lipid trafficking in human leukocytes
Pfisterer, S. G., Brock, I., Kanerva, K., Hlushchenko, I., Paavolainen, L., Ripatti, P., Islam, M. M., Kyttälä, A., Di Taranto, M. D., Scotto di Frega, A., Fortunato, G., Kuusisto, J., Horvath, P., Ripatti, S., Laakso, M. & Ikonen, E., 2022, In: Cell Reports Methods. 2, 2, 17 p., 100166.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2021
ORP2 couples LDL-cholesterol transport to FAK activation by endosomal cholesterol/PI(4,5)P-2 exchange
Takahashi, K., Kanerva, K., Vanharanta, L., Almeida-Souza, L., Lietha, D., Olkkonen, V. M. & Ikonen, E., 15 Jul 2021, In: EMBO Journal. 40, 14, 20 p., 106871.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2020
Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cells
Meneses-Salas, E., García-Melero, A., Kanerva, K., Blanco-Muñoz, P., Morales-Paytuvi, F., Bonjoch, J., Heeren, J., Lu, A., Pol, A., Tebar, F., Ikonen, E., Grewal, T., Enrich, C. & Rentero, C., Jul 2020, In: Cellular and Molecular Life Sciences. 77, 14, p. 2839-2857 19 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2019
Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export
Heybrock, S., Kanerva, K., Meng, Y., Ing, C., Liang, A., Xiong, Z-J., Weng, X., Kim, Y. A., Collins, R., Trimble, W., Pomes, R., Prive, G. G., Annaert, W., Schwake, M., Heeren, J., Lullmann-Rauch, R., Grinstein, S., Ikonen, E., Saftig, P. & Neculai, D., 6 Aug 2019, In: Nature Communications. 10, 12 p., 3521.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Shuttling HDL Cholesterol to the Membrane via Metastable Receptor Multimers
Ikonen, E. & Kanerva, K., 5 Aug 2019, In: Developmental Cell. 50, 3, p. 257-258 2 p.Research output: Contribution to journal › Editorial › Scientific
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2017
Severe neurodegenerative disease in brothers with homozygous mutation in POLR1A
Kara, B., Koroglu, C., Peltonen, K., Steinberg, R. C., Genc, H. M., Holtta-Vuori, M., Guven, A., Kanerva, K., Kotil, T., Solakoglu, S., Zhou, Y., Olkkonen, V. M., Ikonen, E., Laiho, M. & Tolun, A., Feb 2017, In: European Journal of Human Genetics. 25, 3, p. 315-323 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
The endocytic pathways of a secretory granule membrane protein in HEK293 cells: PAM and EGF traverse a dynamic multivesicular body network together
Back, N., Kanerva, K., Kurutihallib, V., Yanik, A., Ikonen, E., Mains, R. E. & Eipper, B. A., Aug 2017, In: European Journal of Cell Biology. 96, 5, p. 407-417 11 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2016
Expression of ODC Antizyme Inhibitor 2 (AZIN2) in Human Secretory Cells and Tissues
Rasila, T., Lehtonen, A., Kanerva, K., Mäkitie, L. T., Haglund, C. & Andersson, L. C., 10 Mar 2016, In: PLoS One. 11, 3, 11 p., 0151175.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2014
Polarized THG Microscopy Identifies Compositionally Different Lipid Droplets in Mammalian Cells
Bautista, G., Pfisterer, S. G., Huttunen, M. J., Ranjan, S., Kanerva, K., Ikonen, E. & Kauranen, M., 18 Nov 2014, In: Biophysical Journal. 107, 10, p. 2230-2336 107 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2013
LDL Cholesterol Recycles to the Plasma Membrane via a Rab8a-Myosin5b-Actin-Dependent Membrane Transport Route
Kanerva, K., Uronen, R-L., Blom, T., Li, S., Bittman, R., Lappalainen, P., Peränen, J., Raposo, G. & Ikonen, E., 11 Nov 2013, In: Developmental Cell. 27, 3, p. 249-262 14 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2011
Cholesterol-regulated signaling and transport in endo-lysosomes
Ikonen, E., Uronen, R-L., Kanerva, K., Blom, J. T., Li, Z. & Bittman, R., 2011, In: Chemistry and Physics of Lipids. 164, p. S9-S9 1 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2010
Antizyme Inhibitor 2 : A Novel Regulator of Cellular Polyamine Homeostasis
Kanerva, K., 2010, Helsinki.Research output: Thesis › Doctoral Thesis › Collection of Articles
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Brain Neurons Express Ornithine Decarboxylase-Activating Antizyme Inhibitor 2 with Accumulation in Alzheimer's Disease
Mäkitie, L., Kanerva, K., Polvikoski, T., Paetau, A. & Andersson, L. C., 2010, In: Brain Pathology. 20, 3, p. 571-580 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Involvement of the polyamine metabolism in actin dynamics and vesicle transport
Andersson, L. C., Kanerva, K. & Mäkitie, L., 2010, 2010 International Polyamine Conference: Progress in medicine and life sciences.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific
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Ornithine decarboxylase antizyme inhibitor 2 regulates intracellular vesicle trafficking
Kanerva, K., Makitie, L. T., Back, N. & Andersson, L. C., 2010, In: Experimental Cell Research. 316, p. 1896-1906 11 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2009
Expression of antizyme inhibitor 2 in mast cells and role of polyamines as selective regulators of serotonin secretion
Kanerva, K., Lappalainen, J., Makitie, L. T., Virolainen, S., Kovanen, P. T. & Andersson, L. C., 2009, In: PLoS One. 4, 8, p. e6858Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
High expression of antizyme inhibitor 2, an activator of ornithine decarboxylase in steroidogenic cells of human gonads
Makitie, L. T., Kanerva, K., Sankila, A. & Andersson, L. C., 2009, In: Histochemistry and Cell Biology. 132, p. 633-638 6 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Ornithine decarboxylase regulates the activity and localization of rhoA via polyamination
Mäkitie, L., Kanerva, K. & Andersson, L. C., 2009, In: Experimental Cell Research. 315, 6, p. 1008-1014 7 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2008
Human ornithine decarboxylase paralogue (ODCp) is an antizyme inhibitor but not an arginine decarboxylase
Kanerva, K., Mäkitie, L., Pelander, A., Heiskala, M. & Andersson, L. C., 2008, In: Biochemical Journal. 409, 1, p. 187-192 6 p.Research output: Contribution to journal › Article › Scientific › peer-review