Photo of Kristiina Mäkinen

Kristiina Mäkinen, Docent, university lecturer

  • PL 56 (Viikinkaari 9)

    00014

    Finland

  • Viikinkaari 1, Biocentre 3

    00790 Helsinki

    Finland

19952020

Research output per year

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Personal profile

Description of research and teaching

Research

Plant health is an increasingly important issue as sufficient food security is endangered by the global climate change and growing population of the world. The research in the group focuses on the molecular mechanisms underlying Potato virus A (PVA) infection. PVA is a member of genus Potyvirus, which is economically the most devastating group of plant RNA viruses. Understanding the different stages of virus infection is a prerequisite for being able to prevent infections. The research in the group is carried out with the advanced techniques of biochemistry, and molecular and cell biology. The aims of  our research are:

 1) to produce novel information of the various stages of the virus multiplication cycle (protein synthesis, RNA replication, virus movement, encapsidation), and how these functions are localized and coordinated within the infected cells.

2) to tackle the disease problem caused by the genus Potyvirus, which is economically the most devastating group of plant viruses. Host factors involved in viral multiplication represent potential targets for virus control. Their identification and functional characterization is one of the major frontiers in virus research.

3) to exploit viruses as gene vectors, viral regulatory sequences as valuable elements in plant expression vectors and virus particles in nanobiotechnology applications.

Teaching

My teaching consists of basic lecture and laboratory courses in biochemistry and gene technology. I have been an organizer and teacher on post graduate courses on plant virology, heterologous protein production in plants and protein interactions and biochemical analyses. I have supervised several MSc and PhD students.

Fields of Science

  • 1183 Plant biology, microbiology, virology
  • plant virology, potyviruses

International and National Collaboration Publications and projects within past five years.

Publications

Insights into the Functions of eIF4E-Binding Motif of VPg in Potato Virus A Infection

Saha, S. & Mäkinen, K., 11 Feb 2020, In : Viruses. 22 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Dynamics of Protein Accumulation from the 3 ' End of Viral RNA Are Different from Those in the Rest of the Genome in Potato Virus A Infection

Saha, S., Hafren, A. & Makinen, K., Oct 2019, In : Journal of Virology. 93, 19, 18 p., ARTN e00721-19.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Introduction to Special Issue of Molecular Plant Pathology - "Extracellular and intracellular perception of plant viruses"

Aranda, M. A., Makinen, K. & Verchot, J., Sep 2019, In : Molecular Plant Pathology. 20, 9, p. 1183-1184 2 p.

Research output: Contribution to journalEditorialScientific

Open Access
File
Open Access

Plant susceptibility genes as a source for potyvirus resistance.

Mäkinen, K., 7 Dec 2019, In : Annals of Applied Biology.

Research output: Contribution to journalReview ArticleScientificpeer-review

Projects

Activities

Federation of European Biochemical Societies - Advanced Courses Committee (External organisation)

Kristiina Mäkinen (Board member)
20202023

Activity: Membership typesMembership or other role in national/international committee, council, board

INRA

Kristiina Mäkinen (Visiting researcher)
29 Sep 20199 Oct 2019

Activity: Visiting an external institution typesAcademic visit to other institution

18th Congress of International-Society-for-Molecular-Plant-Microbe-Interactions (IS-MPMI) - Satellite meeting: Extracellular and Intracellular Perception of Viruses

Kristiina Mäkinen (Member of organizing committee)
14 Jul 2019

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

Plant Gene Editing panel discussionGenome editing for plant improvement – prospects and challenges

Kristiina Mäkinen (Member of organizing committee)
11 Sep 2019

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

Molecular Plant Pathology (Journal)

Miguel Aranda (Editor), Kristiina Mäkinen (Editor), Jeanmarie Verchot (Editor)
Sep 2019

Activity: Publication peer-review and editorial work typesEditor of series