Photo of Kristiina Mäkinen

Kristiina Mäkinen, Docent, university lecturer

  • PL 56 (Viikinkaari 9)

    00014

    Finland

  • Viikinkaari 1, Biocentre 3

    00790 Helsinki

    Finland

19952020

Research activity per year

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Personal profile

Description of research and teaching

Research

Plant health is an increasingly important issue as sufficient food security is endangered by the global climate change and growing population of the world. The research in the group focuses on the molecular mechanisms underlying Potato virus A (PVA) infection. PVA is a member of genus Potyvirus, which is economically the most devastating group of plant RNA viruses. Understanding the different stages of virus infection is a prerequisite for being able to prevent infections. The research in the group is carried out with the advanced techniques of biochemistry, and molecular and cell biology. The aims of  our research are:

 1) to produce novel information of the various stages of the virus multiplication cycle (protein synthesis, RNA replication, virus movement, encapsidation), and how these functions are localized and coordinated within the infected cells.

2) to tackle the disease problem caused by the genus Potyvirus, which is economically the most devastating group of plant viruses. Host factors involved in viral multiplication represent potential targets for virus control. Their identification and functional characterization is one of the major frontiers in virus research.

3) to exploit viruses as gene vectors, viral regulatory sequences as valuable elements in plant expression vectors and virus particles in nanobiotechnology applications.

Teaching

My teaching consists of basic lecture and laboratory courses in biochemistry and gene technology. I have been an organizer and teacher on post graduate courses on plant virology, heterologous protein production in plants and protein interactions and biochemical analyses. I have supervised several MSc and PhD students.

Fields of Science

  • 1183 Plant biology, microbiology, virology
  • plant virology, potyviruses

International and National Collaboration

Publications and projects within past five years.
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