Research output per year
Research output per year
- 23 results
Search results
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2021
The initiation knot is a signaling center required for molar tooth development
Mogollon Figueroa, I., Moustakas-Verho, J. E., Niittykoski, M. J. & Ahtiainen, L., May 2021, In: Development. 148, 9, 16 p., 194597.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2016
Early epithelial signaling center governs tooth budding morphogenesis
Ahtiainen, L., Uski, I., Thesleff, I. & Mikkola, M. L., 12 Sep 2016, In: Journal of Cell Biology. 214, 6, p. 753-767 15 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2014
Directional Cell Migration, but Not Proliferation, Drives Hair Placode Morphogenesis
Ahtiainen, L., Lefebvre, S., Lindfors, P. H., Renvoise, E., Shirokova, V., Vartiainen, M. K., Thesleff, I. & Mikkola, M. L., 10 Mar 2014, In: Developmental Cell. 28, 5, p. 588-602 15 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2013
Oncolytic Adenovirus With Temozolomide Induces Autophagy and Antitumor Immune Responses in Cancer Patients
Liikanen, I., Ahtiainen, L., Hirvinen, M. L. M., Bramante, S., Cerullo, V., Nokisalmi, P., Hemminki, O., Diaconu, I., Pesonen, S., Koski, A., Kangasniemi, L., Pesonen, S. K., Oksanen, M., Laasonen, L., Partanen, K., Joensuu, T., Zhao, F., Kanerva, A. & Hemminki, A., Jun 2013, In: Molecular therapy. 21, 6, p. 1212-1223 12 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2012
Ectodysplasin regulates hormone-independent mammary ductal morphogenesis via NF-κB
Voutilainen, M., Lindfors, P., Lefebvre, S., Ahtiainen, L., Fliniaux, I., Rysti, E., Murtoniemi, M., Schneider, P., Schmidt-Ullrich, R. & Mikkola, M. L., 10 Apr 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 15, p. 5744-5749 6 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Macrophage metalloelastase (MME) as adjuvant for intra-tumoral injection of oncolytic adenovirus and its influence on metastases development
Lavilla Alonso, S., Bauer, M. M. T., Abo Ramadan, U., Ristimäki, A., Halavaara, J. T., Desmond, A., Wang, D., Escutenaire, S., Ahtiainen, L. K., Saksela, K., Tatlisumak, T., Hemminki, A. E. & Pesonen, S., 2012, In: Cancer Gene Therapy. 19, 2, p. 126-134 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Radiation-Induced Upregulation of Gene Expression From Adenoviral Vectors Mediated by DNA Damage Repair and Regulation
Nokisalmi, P., Rajecki, M., Pesonen, S., Escutenaire, S., Soliymani, R., Tenhunen, M., Ahtiainen, L. & Hemminki, A., 2012, In: International Journal of Radiation: Oncology - Biology - Physics. 83, 1, p. 376-384 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Sostdc1 defines the size and number of skin appendage placodes
Närhi, K., Tummers, M., Ahtiainen, L., Itoh, N., Thesleff, I. & Mikkola, M. L., 15 Apr 2012, In: Developmental Biology. 364, 2, p. 149-161 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Sox2+ Stem Cells Contribute to All Epithelial Lineages of the Tooth via Sfrp5+ Progenitors
Juuri, E., Saito, K., Ahtiainen, L., Seidel, K., Tummers, M., Hochedlinger, K., Klein, O. D., Thesleff, I. & Michon, F., 14 Aug 2012, In: Developmental Cell. 23, 2, p. 317-328 12 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2011
Induction of Interferon Pathways Mediates In Vivo Resistance to Oncolytic Adenovirus
Liikanen, I., Monsurro, V., Ahtiainen, L., Raki, M., Hakkarainen, T., Diaconu, I., Escutenaire, S., Hemminki, O., Dias, J. D., Cerullo, V., Kanerva, A., Pesonen, S., Marzioni, D., Colombatti, M. & Hemminki, A., 2011, In: Molecular therapy. 19, 10, p. 1858-1866 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
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In vivo and in vitro distribution of type 5 and fiber-modified oncolytic adenoviruses in human blood compartments
Escutenaire, S., Cerullo, V., Diaconu, I., Ahtiainen, L., Hannuksela, P., Oksanen, M., Haavisto, E., Karioja-Kallio, A., Holm, S-L., Kangasniemi, L., Ribacka, C., Kauppinen, S., Joensuu, T. K., Arstila, T. P., Pesonen, S., Kanerva, A. & Hemminki, A., 2011, In: Annals of Medicine. 43, 2, p. 151-163 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Safety of Glucocorticoids in Cancer Patients Treated with Oncolytic Adenoviruses
Rajecki, M., Raki, M., Escutenaire, S., Pesonen, S., Cerullo, V., Helminen, A., Hannuksela, P., Partanen, K., Laasonen, L., Joensuu, T., Kangasniemi, L., Haavisto, E., Kanerva, A., Ahtiainen, L. & Hemminki, A., 2011, In: Molecular Pharmaceutics. 8, 1, p. 93-103 11 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2010
Adenoviral E4ORF3 and E4ORF6 proteins, but not E1B55K, increase killing of cancer cells by radiotherapy in vivo
Liikanen, I., Dias, J. D., Nokisalmi, P., Sloniecka, M., Kangasniemi, L., Rajecki, M., Dobner, T., Tenhunen, M., Kanerva, A., Pesonen, S., Ahtiainen, L. & Hemminki, A., 2010, In: International Journal of Radiation: Oncology - Biology - Physics. 78, 4, p. 1201-1209 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Defects in Innate Immunity Render Breast Cancer Initiating Cells Permissive to Oncolytic Adenovirus
Ahtiainen, L., Mirantes, C., Jahkola, T., Escutenaire, S., Diaconu, I., Osterlund, P., Kanerva, A., Cerullo, V. & Hemminki, A., 2010, In: PLoS One. 5, 11, p. e13859 15 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Oncolytic Adenovirus Coding for Granulocyte Macrophage Colony-Stimulating Factor Induces Antitumoral Immunity in Cancer Patients
Cerullo, V., Pesonen, S., Diaconu, I., Escutenaire, S., Arstila, P. T., Ugolini, M., Nokisalmi, P., Raki, M., Laasonen, L., Sarkioja, M., Rajecki, M., Kangasniemi, L., Guse, K., Helminen, A., Ahtiainen, L., Ristimäki, A., Räisänen-Sokolowski, A., Haavisto, E., Oksanen, M., Karli, E., & 6 others, 2010, In: Cancer Research. 70, 11, p. 4297-4309 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Oncolytic Adenovirus ICOVIR-7 in Patients with Advanced and Refractory Solid Tumors
Nokisalmi, P., Pesonen, S., Escutenaire, S., Sarkioja, M., Raki, M., Cerullo, V., Laasonen, L., Alemany, R., Rojas, J., Cascallo, M., Guse, K., Rajecki, M., Kangasniemi, L., Haavisto, E., Karioja-Kallio, A., Hannuksela, P., Oksanen, M. K., Kanerva, A., Joensuu, T., Ahtiainen, L., & 1 others, 2010, In: Clinical Cancer Research. 16, p. 3035-3043 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2009
Mre11 inhibition by oncolytic adenovirus associates with autophagy and underlies synergy with ionizing radiation
Rajecki, M., af Hällström, T., Hakkarainen, T., Nokisalmi, P., Hautaniemi, S., Nieminen, A. I., Tenhunen, M., Rantanen, V., Desmond, R. A., Chen, D-T., Guse, K., Stenman, U-H., Gargini, R., Kapanen, M., Klefström, J., Kanerva, A., Pesonen, S., Ahtiainen, L. & Hemminki, A., 2009, In: International Journal of Cancer. 125, 10, p. 2441-2449 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2007
Palmitoyl protein thioesterase 1 (Ppt1)-deficient mouse neurons show alterations in cholesterol metabolism and calcium homeostasis prior to synaptic dysfunction
Ahtiainen, L., Kolikova, J., Mutka, A-L., Luiro, K., Gentile, M., Ikonen, E., Khiroug, L., Jalanko, A. & Kopra, O., 2007, In: Neurobiology of Disease. 28, p. 52-64 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Unravelling molecular and cellular disease mechanisms in Infantile Neuronal Ceroid Lipofuscinosis (INCL)
Ahtiainen, L. K., 2007, Helsinki: Kansanterveyslaitos. 103 p.Research output: Thesis › Doctoral Thesis › Collection of Articles
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2006
Palmitoyl protein thioesterase 1 (PPT1) deficiency causes endocytic defects connected to abnormal saposin processing
Ahtiainen, L., Luiro, K., Kauppi, M., Tyynela, J., Kopra, O. & Jalanko, A., 2006, In: Experimental Cell Research. 312, 9, p. 1540-1553 14 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2004
Bone marrow transplantation in young aspartylglucosaminuria mice: improved clearance of lysosomal storage in brain by using wild type as compared to heterozygote donors
Laine, M., Ahtiainen, L. K., Rapola, J., Richter, J. & Jalanko, A., 2004, In: Bone Marrow Transplantation. 34, 11, p. 1001-1003 3 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Interconnections of CLN3, Hook1 and Rab proteins link Batten disease to defects in the endocytic pathway
Luiro, K., Yliannala, K., Ahtiainen, L., Maunu, H., Jarvela, I., Kyttala, A. & Jalanko, A., 2004, In: Human Molecular Genetics. 13, p. 3017-3027 11 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2003
Palmitoyl protein thioesterase 1 is targeted to the axons in neurons
Ahtiainen, L., Van Diggelen, O. P., Jalanko, A. & Kopra, O., 2003, In: Journal of Comparative Neurology. 455, p. 368-377 10 p.Research output: Contribution to journal › Article › Scientific › peer-review