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Laura Ahtiainen

  • Viikinkaari 5, Biocenter 2

    00790 Helsinki

    Finland

20032016

Research output per year

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Publications

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Article
2016

Early epithelial signaling center governs tooth budding morphogenesis

Ahtiainen, L., Uski, I., Thesleff, I. & Mikkola, M. L., 12 Sep 2016, In : Journal of Cell Biology. 214, 6, p. 753-767 15 p.

Research output: Contribution to journalArticleScientificpeer-review

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2014

Directional Cell Migration, but Not Proliferation, Drives Hair Placode Morphogenesis

Ahtiainen, L., Lefebvre, S., Lindfors, P. H., Renvoise, E., Shirokova, V., Vartiainen, M. K., Thesleff, I. & Mikkola, M. L., 10 Mar 2014, In : Developmental Cell. 28, 5, p. 588-602 15 p.

Research output: Contribution to journalArticleScientificpeer-review

2013

Oncolytic Adenovirus With Temozolomide Induces Autophagy and Antitumor Immune Responses in Cancer Patients

Liikanen, I., Ahtiainen, L., Hirvinen, M. L. M., Bramante, S., Cerullo, V., Nokisalmi, P., Hemminki, O., Diaconu, I., Pesonen, S., Koski, A., Kangasniemi, L., Pesonen, S. K., Oksanen, M., Laasonen, L., Partanen, K., Joensuu, T., Zhao, F., Kanerva, A. & Hemminki, A., Jun 2013, In : Molecular therapy. 21, 6, p. 1212-1223 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2012

Ectodysplasin regulates hormone-independent mammary ductal morphogenesis via NF-κB

Voutilainen, M., Lindfors, P., Lefebvre, S., Ahtiainen, L., Fliniaux, I., Rysti, E., Murtoniemi, M., Schneider, P., Schmidt-Ullrich, R. & Mikkola, M. L., 10 Apr 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 15, p. 5744-5749 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Macrophage metalloelastase (MME) as adjuvant for intra-tumoral injection of oncolytic adenovirus and its influence on metastases development

Lavilla Alonso, S., Bauer, M. M. T., Abo Ramadan, U., Ristimäki, A., Halavaara, J. T., Desmond, A., Wang, D., Escutenaire, S., Ahtiainen, L. K., Saksela, K., Tatlisumak, T., Hemminki, A. E. & Pesonen, S., 2012, In : Cancer Gene Therapy. 19, 2, p. 126-134 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Radiation-Induced Upregulation of Gene Expression From Adenoviral Vectors Mediated by DNA Damage Repair and Regulation

Nokisalmi, P., Rajecki, M., Pesonen, S., Escutenaire, S., Soliymani, R., Tenhunen, M., Ahtiainen, L. & Hemminki, A., 2012, In : International Journal of Radiation: Oncology - Biology - Physics. 83, 1, p. 376-384 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Sostdc1 defines the size and number of skin appendage placodes

Närhi, K., Tummers, M., Ahtiainen, L., Itoh, N., Thesleff, I. & Mikkola, M. L., 15 Apr 2012, In : Developmental Biology. 364, 2, p. 149-161 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Sox2+ Stem Cells Contribute to All Epithelial Lineages of the Tooth via Sfrp5+ Progenitors

Juuri, E., Saito, K., Ahtiainen, L., Seidel, K., Tummers, M., Hochedlinger, K., Klein, O. D., Thesleff, I. & Michon, F., 14 Aug 2012, In : Developmental Cell. 23, 2, p. 317-328 12 p.

Research output: Contribution to journalArticleScientificpeer-review

2011

Induction of Interferon Pathways Mediates In Vivo Resistance to Oncolytic Adenovirus

Liikanen, I., Monsurro, V., Ahtiainen, L., Raki, M., Hakkarainen, T., Diaconu, I., Escutenaire, S., Hemminki, O., Dias, J. D., Cerullo, V., Kanerva, A., Pesonen, S., Marzioni, D., Colombatti, M. & Hemminki, A., 2011, In : Molecular therapy. 19, 10, p. 1858-1866 9 p.

Research output: Contribution to journalArticleScientificpeer-review

In vivo and in vitro distribution of type 5 and fiber-modified oncolytic adenoviruses in human blood compartments

Escutenaire, S., Cerullo, V., Diaconu, I., Ahtiainen, L., Hannuksela, P., Oksanen, M., Haavisto, E., Karioja-Kallio, A., Holm, S-L., Kangasniemi, L., Ribacka, C., Kauppinen, S., Joensuu, T. K., Arstila, T. P., Pesonen, S., Kanerva, A. & Hemminki, A., 2011, In : Annals of Medicine. 43, 2, p. 151-163 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Safety of Glucocorticoids in Cancer Patients Treated with Oncolytic Adenoviruses

Rajecki, M., Raki, M., Escutenaire, S., Pesonen, S., Cerullo, V., Helminen, A., Hannuksela, P., Partanen, K., Laasonen, L., Joensuu, T., Kangasniemi, L., Haavisto, E., Kanerva, A., Ahtiainen, L. & Hemminki, A., 2011, In : Molecular Pharmaceutics. 8, 1, p. 93-103 11 p.

Research output: Contribution to journalArticleScientificpeer-review

2010

Adenoviral E4ORF3 and E4ORF6 proteins, but not E1B55K, increase killing of cancer cells by radiotherapy in vivo

Liikanen, I., Dias, J. D., Nokisalmi, P., Sloniecka, M., Kangasniemi, L., Rajecki, M., Dobner, T., Tenhunen, M., Kanerva, A., Pesonen, S., Ahtiainen, L. & Hemminki, A., 2010, In : International Journal of Radiation: Oncology - Biology - Physics. 78, 4, p. 1201-1209 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Defects in Innate Immunity Render Breast Cancer Initiating Cells Permissive to Oncolytic Adenovirus

Ahtiainen, L., Mirantes, C., Jahkola, T., Escutenaire, S., Diaconu, I., Osterlund, P., Kanerva, A., Cerullo, V. & Hemminki, A., 2010, In : PLoS One. 5, 11, p. e13859 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Oncolytic Adenovirus Coding for Granulocyte Macrophage Colony-Stimulating Factor Induces Antitumoral Immunity in Cancer Patients

Cerullo, V., Pesonen, S., Diaconu, I., Escutenaire, S., Arstila, P. T., Ugolini, M., Nokisalmi, P., Raki, M., Laasonen, L., Sarkioja, M., Rajecki, M., Kangasniemi, L., Guse, K., Helminen, A., Ahtiainen, L., Ristimäki, A., Räisänen-Sokolowski, A., Haavisto, E., Oksanen, M., Karli, E. & 6 others, Karioja-Kallio, A., Holm, S-L., Kouri, M., Joensuu, T., Kanerva, A. & Hemminki, A., 2010, In : Cancer Research. 70, 11, p. 4297-4309 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Oncolytic Adenovirus ICOVIR-7 in Patients with Advanced and Refractory Solid Tumors

Nokisalmi, P., Pesonen, S., Escutenaire, S., Sarkioja, M., Raki, M., Cerullo, V., Laasonen, L., Alemany, R., Rojas, J., Cascallo, M., Guse, K., Rajecki, M., Kangasniemi, L., Haavisto, E., Karioja-Kallio, A., Hannuksela, P., Oksanen, M. K., Kanerva, A., Joensuu, T., Ahtiainen, L. & 1 others, Hemminki, A., 2010, In : Clinical Cancer Research. 16, p. 3035-3043 9 p.

Research output: Contribution to journalArticleScientificpeer-review

2009

Mre11 inhibition by oncolytic adenovirus associates with autophagy and underlies synergy with ionizing radiation

Rajecki, M., af Hällström, T., Hakkarainen, T., Nokisalmi, P., Hautaniemi, S., Nieminen, A. I., Tenhunen, M., Rantanen, V., Desmond, R. A., Chen, D-T., Guse, K., Stenman, U-H., Gargini, R., Kapanen, M., Klefström, J., Kanerva, A., Pesonen, S., Ahtiainen, L. & Hemminki, A., 2009, In : International Journal of Cancer. 125, 10, p. 2441-2449 9 p.

Research output: Contribution to journalArticleScientificpeer-review

2007

Palmitoyl protein thioesterase 1 (Ppt1)-deficient mouse neurons show alterations in cholesterol metabolism and calcium homeostasis prior to synaptic dysfunction

Ahtiainen, L., Kolikova, J., Mutka, A-L., Luiro, K., Gentile, M., Ikonen, E., Khiroug, L., Jalanko, A. & Kopra, O., 2007, In : Neurobiology of Disease. 28, p. 52-64 13 p.

Research output: Contribution to journalArticleScientificpeer-review

2006

Palmitoyl protein thioesterase 1 (PPT1) deficiency causes endocytic defects connected to abnormal saposin processing

Ahtiainen, L., Luiro, K., Kauppi, M., Tyynela, J., Kopra, O. & Jalanko, A., 2006, In : Experimental Cell Research. 312, 9, p. 1540-1553 14 p.

Research output: Contribution to journalArticleScientificpeer-review

2004

Bone marrow transplantation in young aspartylglucosaminuria mice: improved clearance of lysosomal storage in brain by using wild type as compared to heterozygote donors

Laine, M., Ahtiainen, L. K., Rapola, J., Richter, J. & Jalanko, A., 2004, In : Bone Marrow Transplantation. 34, 11, p. 1001-1003 3 p.

Research output: Contribution to journalArticleScientificpeer-review

Interconnections of CLN3, Hook1 and Rab proteins link Batten disease to defects in the endocytic pathway

Luiro, K., Yliannala, K., Ahtiainen, L., Maunu, H., Jarvela, I., Kyttala, A. & Jalanko, A., 2004, In : Human Molecular Genetics. 13, p. 3017-3027 11 p.

Research output: Contribution to journalArticleScientificpeer-review

2003

Palmitoyl protein thioesterase 1 is targeted to the axons in neurons

Ahtiainen, L., Van Diggelen, O. P., Jalanko, A. & Kopra, O., 2003, In : Journal of Comparative Neurology. 455, p. 368-377 10 p.

Research output: Contribution to journalArticleScientificpeer-review