Photo of Lauri Aaltonen

Lauri Aaltonen, Professor

  • PL 63 (Haartmaninkatu 8)

    00014

    Finland

1992 …2020

Research output per year

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Publications

Preferential amplification of AURKA 91A (Ile31) in familial colorectal cancers

Hienonen, T., Salovaara, R., Mecklin, J-P., Järvinen, H. J., Karhu, A. & Aaltonen, L. A., 2006, In : International Journal of Cancer. 118, 2, p. 505-508 4 p.

Research output: Contribution to journalArticleScientificpeer-review

PPP2R1B gene in chronic lymphocytic leukemias and mantle cell lymphomas

Zhu, Y., Loukola, A., Monni, O., Kuokkanen, K., Franssila, K., Elonen, E., Vilpo, J., Joensuu, H., Kere, J., Aaltonen, L. & Knuutila, S., 2001, In : Leukemia. 2001, 41, p. 177-183 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Population distribution and ancestry of the cancer protective MDM2 SNP285 (rs117039649)

Knappskog, S., Gansmo, L. B., Dibirova, K., Metspalu, A., Cybulski, C., Peterlongo, P., Aaltonen, L., Vatten, L., Romundstad, P., Hveem, K., Devilee, P., Evans, G. D., Lin, D., Van Camp, G., Manolopoulos, V. G., Osorio, A., Milani, L., Ozcelik, T., Zalloua, P., Mouzaya, F. & 17 others, Bliznetz, E., Balanovska, E., Pocheshkova, E., Kucinskas, V., Atramentova, L., Nymadawa, P., Titov, K., Lavryashina, M., Yusupov, Y., Bogdanova, N., Koshel, S., Zamora, J., Wedge, D. C., Charlesworth, D., Doerk, T., Balanovsky, O. & Lonning, P. E., 30 Sep 2014, In : Oncotarget. 5, 18, p. 8223-8234 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Population-based molecular detection of hereditary nonpolyposis colorectal cancer

Salovaara, R., Loukola, A., Kristo, P., Kaariainen, H., Ahtola, H., Eskelinen, M., Harkonen, N., Julkunen, R., Kangas, E., Ojala, S., Tulikoura, J., Valkamo, E., Mecklin, JP., Aaltonen, LA. & de la Chapelle, A., Jun 2000, In : Journal of Clinical Oncology. 18, 11, p. 2193-2200 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Pituitary adenoma predisposition caused by germline mutations in the AIP gene

Vierimaa, O., Georgitsi, M., Lehtonen, R., Vahteristo, P., Kokko, A., Raitila, A., Tuppurainen, K., Ebeling, T., Salmela, P. I., Paschke, R., Gundogdu, S., De Menis, E., Mäkinen, M. J., Launonen, V., Karhu, A. & Aaltonen, L. A., 2006, In : Science. 312, 5777, p. 1228-1230 3 p.

Research output: Contribution to journalArticleScientificpeer-review

Phosphoprotein Keratin 23 accumulates in MSS but not MSI colon cancers in vivo and impacts viability and proliferation in vitro

Birkenkamp-Demtroder, K., Mansilla, F., Sorensen, F. B., Kruhoffer, M., Cabezon, T., Christensen, L. L., Aaltonen, L. A., Verspaget, H. W. & Orntoft, T. F., 2007, In : Molecular oncology. 1, p. 181-195 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Peutz-Jeghers disease: most, but not all, families are compatible with linkage to 19p13.3

Olschwang, S., Markie, D., Seal, S., Neale, K., Phillips, R., Cottrell, S., Ellis, I., Hodgson, S., Zauber, P., Spigelman, A., Iwama, T., Loff, S., McKeown, C., Marchese, C., Sampson, J., Davies, S., Talbot, I., Wyke, J., Thomas, G., Bodmer, W. & 7 others, Hemminki, A., Avizienyte, E., de la Chapelle, A., Aaltonen, L., Stratton, M., Houlston, R. & Tomlinson, I., 1998, In : Journal of Medical Genetics. 35, p. 42-44 3 p.

Research output: Contribution to journalArticleScientificpeer-review

Periytyvä syöpä

Translated title of the contribution: Hereditary cancerMecklin, J-P., Peltomäki, P. T., Aaltonen, L. A. & Kääriäinen, H., 1995, In : Suomen lääkärilehti. 50, 18-19, p. 2057-2064

Research output: Contribution to journalReview ArticleScientificpeer-review

Periytyvän paksusuolisyövän yleisyys ja molekyyligeneettinen seulonta Suomessa

Aaltonen, L. A., Salovaara, R., Krio, P., Canzian, F., Hemminki, A., Percesepe, A., Peltomäki, P. T., de la Chapelle, A., Chadwick, R. B., Kääriäinen, H., Ahtola, H., Eskelinen, M., Härkönen, N., Julkunen, R., Kangas, E., Ojala, S., Tulikoura, J., Valkamo, E., Järvinen, H. & Mecklin, J-P., 1998, In : Duodecim. 114, p. 2084-2085

Research output: Contribution to journalReview ArticleScientificpeer-review

Periytyvän kasvainalttiuden molekyylitausta: Äyräpään luento

Aaltonen, L. A., 2006, In : Duodecim. 122, 18, p. 2221-2230

Research output: Contribution to journalArticleScientific

Paksusuolisyövälle altistavat geenivirheet ja niiden diagnostiikka

Aaltonen, L. A. & Järvinen, H. J., 2007, Gastroenterologia ja hepatologia. Helsinki: Duodecim, p. 544-549 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Paksusuolisyövälle altistavat geenivirheet ja niiden diagnostiikka

Translated title of the contribution: Mutations predisposing to colon cancer and their diagnosisAaltonen, L. A. & Peltomäki, P. T., 2000, Gastroenterologia. K. H. M. F. E. K. P. P. (ed.). 2nd ed. Kustannus Oy Duodecim, p. 844-849

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

p53 codon 72 and MDM2 SNP309 polymorphisms and age of colorectal cancer onset in Lynch syndrome

Sotamaa, K., Liyanarachchi, S., Mecklin, J-P., Järvinen, H. J., Aaltonen, L. A., Peltomäki, P. & Chapelle, A. D. L., 2005, In : Clinical Cancer Research. 11, 19, p. 6840-6844 5 p.

Research output: Contribution to journalArticleScientificpeer-review

p53, CHK2, and CHK1 genes in Finnish families with Li-Fraumeni syndrome: Further evidence of CHK2 in inherited cancer predisposition

Vahteristo, P., Tamminen, A., Karvinen, P., Eerola, H., Eklund, C., Aaltonen, L. A., Blomqvist, C., Aittomäki, K. & Nevanlinna, H., 2001, In : Cancer Research. 61, p. 5718-5722 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19

Park, M. J., Shen, H., Spaeth, J. M., Tolvanen, J. H., Failor, C., Knudtson, J. F., McLaughlin, J., Halder, S. K., Yang, Q., Bulun, S. E., Al-Hendy, A., Schenken, R. S., Aaltonen, L. A. & Boyer, T. G., 30 Mar 2018, In : Journal of Biological Chemistry. 293, 13, p. 4870-4882 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Numbers of mutations to different types of colorectal cancer

Calabrese, P., Mecklin, J-P., Järvinen, H. J., Aaltonen, L. A., Tavare, S. & Shibata, D., 2005, In : BMC Cancer. 5, 126, 7 p.

Research output: Contribution to journalArticleScientificpeer-review

No support for endoscopic surveillance for gastric cancer in hereditary non-polyposis colorectal cancer

Renkonen-Sinisalo, L., Sipponen, P., Aarnio, M., Julkunen, R., Aaltonen, L. A., Sarna, S., Jarvinen, H. J. & Mecklin, J. P., 2002, In : Scandinavian Journal of Gastroenterology. 37, 5, p. 574-577 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Nordic collaborative study of the BARD1 Cys557Ser allele in 3956 patients with cancer: enrichment in familial BRCA1/BRCA2 mutation-negative breast cancer but not in other malignancies

Karppinen, S-M., Barkardottir, R. B., Backenhorn, K., Sydenham, T., Syrjäkoski, K., Schleutker, J., Ikonen, T., Pylkäs, K., Rapakko, K., Erkko, H., Johannesdottir, G., Gerdes, A-M., Thomassen, M., Agnarsson, B. A., Grip, M., Kallioniemi, A., Kere, J., Aaltonen, L. A., Arason, A., Møller, P. & 3 others, Kruse, T. A., Borg, Å. & Winqvist, R., 2006, In : Journal of Medical Genetics. 43, 11, p. 856-862 7 p.

Research output: Contribution to journalArticleScientificpeer-review

No MSH6 germline mutations in breast cancer families with colorectal and/or endometrial cancer

Vahteristo, P., Ojala, S., Tamminen, A., Tommiska, J., Sammalkorpi, H., Kiuru-Kuhlefelt, S., Eerola, H., Aaltonen, L. A., Aittomäki, K. & Nevanlinna, H., 2005, In : Journal of Medical Genetics. 42, 4, p. e22 5 p.

Research output: Contribution to journalArticleScientificpeer-review

No germline FH mutations in familial breast cancer patients

Kiuru, M. H. T., Lehtonen, R., Eerola, H., Aittomäki, K., Blomqvist, C., Nevanlinna, H., Aaltonen, L. A. & Launonen, V., 2005, In : European Journal of Human Genetics. 13, 4, p. 506-509 4 p.

Research output: Contribution to journalArticleScientificpeer-review

No evidence of somatic aryl hydrocarbon receptor interacting protein mutations in sporadic endocrine neoplasia

Raitila, A., Georgitsi, M., Karhu, A., Tuppurainen, K., Mäkinen, M. J., Birkenkamp-Demtröder, K., Salmenkivi, K., Ørntoft, T. F., Arola, J., Launonen, V., Vahteristo, P. & Aaltonen, L. A., 2007, In : Endocrine - Related Cancer. 14, 3, p. 901-906 6 p.

Research output: Contribution to journalArticleScientificpeer-review

No evidence of RET germline mutations in familial pituitary adenoma

Heliovaara, E., Tuupanen, S., Ahlsten, M., Hodgson, S., de Menis, E., Kuismin, O., Izatt, L., Gardner, R. J. M., Gundogdu, S., Lucassen, A., Arola, J., Tuomisto, A., Makinen, M., Karhu, A. & Aaltonen, L. A., 2011, In : Journal of Molecular Endocrinology. 46, 1, p. 1-8 8 p.

Research output: Contribution to journalArticleScientificpeer-review

No evidence of Peutz-Jeghers syndrome gene LKB1 involvement in left-sided colorectal carcinomas

Launonen, T., Avizienyte, E., Loukola, A., Laiho, P., Salovaara, R., Mecklin, JP., Oku, A., Shimane, M., Kim, HC., Kim, JC., Nezu, J. & Aaltonen, LA., 1 Feb 2000, In : Cancer Research. 60, 3, p. 546-548 3 p.

Research output: Contribution to journalArticleScientificpeer-review

No evidence of microsatellite instability in bone tumors

Tarkkanen, M., Aaltonen, L. A., Böhling, T. O., Kivioja, A. H., Karaharju, E., Elomaa, A. I. & Knuutila, Y. S., 1996, In : British Journal of Cancer. 74, p. 453-455

Research output: Contribution to journalArticleScientificpeer-review

No evidence for dual role of loss of heterozygosity in hereditary non-polyposis colorectal cancer

Tuupanen, S., Karhu, A., Järvinen, H. J., Mecklin, J-P., Launonen, V. & Aaltonen, L. A., 2007, In : Oncogene. 26, 17, p. 2513-2517 5 p.

Research output: Contribution to journalArticleScientificpeer-review

No evidence for association of NOD2 R702W and G908R with colorectal cancer

Tuupanen, S., Alhopuro, P., Mecklin, J-P., Järvinen, H. J. & Aaltonen, L. A., 2007, In : International Journal of Cancer. 121, 1, p. 76-79 4 p.

Research output: Contribution to journalArticleScientificpeer-review

No evidence for a genetic modifier for renal cell cancer risk in HLRCC syndrome

Vahteristo, P., Koski, T. A., Naatsaari, L., Kiuru, M., Karhu, A., Herva, R., Sallinen, S-L., Vierimaa, O., Bjorck, E., Richard, S., Gardie, B., Bessis, D., Van Glabeke, E., Blanco, I., Houlston, R., Senter, L., Hietala, M., Aittomaki, K., Aaltonen, L. A., Launonen, V. & 1 others, Lehtonen, R., 2010, In : Familial Cancer. 9, p. 245-251 7 p.

Research output: Contribution to journalArticleScientificpeer-review

New Target Genes in Endometrial Tumors Show a Role for the Estrogen-Receptor Pathway in Microsatellite-Unstable Cancers

Ferreira, A. M., Tuominen, I., Sousa, S., Gerbens, F., van Dijk-Bos, K., Osinga, J., Kooi, K. A., Sanjabi, B., Esendam, C., Oliveira, C., Terpstra, P., Hardonk, M., van der Sluis, T., Zazula, M., Stachura, J., van der Zee, A. G., Hollema, H., Sijmons, R. H., Aaltonen, L. A., Seruca, R. & 2 others, Hofstra, R. M. W. & Westers, H., Dec 2014, In : Human Mutation. 35, 12, p. 1514-1523 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Nationwide Registry-Based Analysis of Cancer Clustering Detects Strong Familial Occurrence of Kaposi Sarcoma

Kaasinen, E., Aavikko, M., Vahteristo, P., Patama, T., Li, Y., Saarinen, S., Kilpivaara, O., Pitkänen, E., Knekt, P., Laaksonen, M., Lehtonen, R., Artama, M., Aaltonen, L. A. & Pukkala, E., 24 Jan 2013, In : PLoS One. 8, 1, p. Article Number: e55209 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Mutations of a MutS homolog in hereditary non-polyposis colorectal cancer

LEACH, F. S., NICOLAIDES, N. C., PAPADOPOULOS, N., LIU, B., JEN, J., PARSONS, R., Peltomäki, P., SISTONEN, P., Aaltonen, L. A., NYSTROMLAHTI, M., GUAN, X. Y., ZHANG, J., MELTZER, P. S., YU, J. W., KAO, F. T., CHEN, D. J., CEROSALETTI, K. M., FOURNIER, R. E. K., TODD, S., LEWIS, T. & 15 others, LEACH, R. J., NAYLOR, S. L., WEISSENBACH, J., MECKLIN, J. P., Järvinen, H., PETERSEN, G. M., HAMILTON, S. R., GREEN, J., JASS, J., WATSON, P., LYNCH, H. T., TRENT, J. M., de la Chapelle, A., KINZLER, K. W. & VOGELSTEIN, B., 1993, In : Cell. 75, p. 1215-1225 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Mutations in two short noncoding mononucleotide repeats in most microsatellite-unstable colorectal cancers

Hienonen, T., Sammalkorpi, H., Enholm, S., Alhopuro, P., Barber, T. D., Lehtonen, R., Nupponen, N. N., Lehtonen, H., Salovaara, R., Mecklin, J-P., Järvinen, H. J., Koistinen, R., Arango, D., Launonen, V., Vogelstein, B., Karhu, A. & Aaltonen, L. A., 2005, In : Cancer Research. 65, 11, p. 4607-4613 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Mutations in the SMAD4/DPC4 gene in juvenile polyposis

Howe, J. R., Roth, S., Ringold, J. C., Summers, R. W., Jarvinen, H. J., Sistonen, P., Tomlinson, I. P. M., Houlston, R. S., Bevan, S., Mitros, F. A., Stone, E. M. & Aaltonen, L. A., 1998, In : Informing Science. 280, p. 1086-1088 3 p.

Research output: Contribution to journalArticleScientificpeer-review

Mutations in the Circadian Gene CLOCK in Colorectal Cancer

Alhopuro, P., Björklund, M., Sammalkorpi, H. P., Turunen, M., Tuupanen, S. J., Bistrom, M., Niittymäki, I., Lehtonen, H., Kivioja, T., Launonen, V., Saharinen, J. M. N., Nousiainen, K. J., Hautaniemi, S., Nuorva, K., Mecklin, J-P., Järvinen, H., Orntoft, T., Arango, D., Lehtonen, R. J., Karhu, A. I. & 2 others, Taipale, J. & Aaltonen, L. A., 2010, In : Molecular Cancer Research. 8, 7, p. 952-960 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Mutations in BRIP1 confer high risk of ovarian cancer

Rafnar, T., Gudbjartsson, D. F., Sulem, P., Jonasdottir, A., Sigurdsson, A., Jonasdottir, A., Besenbacher, S., Lundin, P., Stacey, S. N., Gudmundsson, J., Magnusson, O. T., le Roux, L., Orlygsdottir, G., Helgadottir, H. T., Johannsdottir, H., Gylfason, A., Tryggvadottir, L., Jonasson, J. G., de Juan, A., Ortega, E. & 25 others, Ramon-Cajal, J. M., Garcia-Prats, M. D., Mayordomo, C., Panadero, A., Rivera, F., Aben, K. K. H., van Altena, A. M., Massuger, L. F. A. G., Aavikko, M., Kujala, P. M., Staff, S., Aaltonen, L. A., Olafsdottir, K., Bjornsson, J., Kong, A., Salvarsdottir, A., Saemundsson, H., Olafsson, K., Benediktsdottir, K. R., Gulcher, J., Masson, G., Kiemeney, L. A., Mayordomo, J. I., Thorsteinsdottir, U. & Stefansson, K., 2011, In : Nature Genetics. 43, 11, p. 1104-U91 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Mutation screening of fumarate hydratase by multiplex ligation-dependent probe amplification: detection of exonic deletion in a patient with leiomyomatosis and renal cell cancer

Koski (Ahvenainen), T. A., Lehtonen, H. J., Lehtonen, R., Vahteristo, P., Aittomäki, K., Baynam, G., Dommering, C., Eng, C., Gruber, S. B., Grönberg, H., Harvima, R., Herva, R., Hietala, M., Kujala, M., Kääriäinen, H., Sunde, L., Vierimaa, O., Pollard, P. J., Tomlinson, I. P., Björck, E. & 2 others, Aaltonen, L. A. & Launonen, V., 2008, In : Cancer Genetics and Cytogenetics. 183, 2, p. 83-88 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Mutations and impaired function of LKB1 in familial and non-familial Peutz-Jeghers syndrome and a sporadic testicular cancer

Ylikorkala, A., Avizienyte, E., Tomlinson, I. P. M., Tiainen, M., Roth, S., Loukola, A., Hemminki, A., Johansson, M., Sistonen, P., Markie, D., Neale, K., Phillips, R., Zauber, P., Twama, T., Sampson, J., Järvinen, H., Makela, T. P. & Aaltonen, L. A., 1999, In : Human Molecular Genetics. 8, p. 45-51 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRAD alpha, and MO25 alpha, in Peutz-Jeghers syndrome

Alhopuro, P., Katajisto, P., Lehtonen, R., Ylisaukko-oja, S. K., Näätsaari, L., Karhu, A., Westerman, A. M., Wilson, J. H. P., de Rooij, F. W. M., Vogel, T., Moeslein, G., Tomlinson, I. P., Aaltonen, L. A., Mäkelä, T. P. & Launonen, V., 2005, In : British Journal of Cancer. 92, p. 1126-1129 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADalpha, and MO25alpha, in Peutz-Jeghers syndrome

Alhopuro, P., Katajisto, P., Lehtonen, R. J., Ylisaukko-oja, S., Näätäsaari, L., Karhu, A., Westerman, A. M., Wilson, J. H. P., de Rooij, F. W. M., Vogel, T., Moeslein, G., Tomlinson, I. P. M., Aaltonen, L. A., Mäkelä, T. P. & Launonen, V., 2005, In : British Journal of Cancer. 92, 6, p. 1126-1129 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Mutation analysis of SMAD2, SMAD3, and SMAD4 genes in hereditary non-polyposis colorectal cancer

Roth, S., Johansson, M., Loukola, A., Peltomäki, P., Järvinen, H., Mecklin, J. P. & Aaltonen, L. A., 2000, In : Journal of Medical Genetics. 37, 4, p. 298-300 3 p.

Research output: Contribution to journalArticleScientificpeer-review

Mutation analysis of MYH11 in acute myeloid leukemia

Sammalkorpi, H., Alhopuro, P., Niittymäki, I., Ørntoft, T. F., Hokland, P., Karhu, A. & Aaltonen, L. A., 2008, In : Leukemia & lymphoma. 49, 9, p. 1829-1831 3 p.

Research output: Contribution to journalArticleScientificpeer-review

Mutation analysis of MEN1, HRPT2, CASR, CDKN1B, and AIP genes in primary hyperparathyroidism patients with features of genetic predisposition

Vierimaa, O., Villablanca, A., Alimov, A., Georgitsi, M., Raitila, A., Vahteristo, P., Larsson, C., Ruokonen, A., Eloranta, E., Ebeling, T. M. L., Ignatius, J., Aaltonen, L. A., Leisti, J. & Salmela, P. I., 2009, In : Journal of Endocrinological Investigation. 32, 6, p. 512-518 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Mutation analysis of components of the Mediator kinase module in MED12 mutation-negative uterine leiomyomas

Mäkinen, N., Heinonen, H-R., Sjoberg, J., Taipale, J., Vahteristo, P. & Aaltonen, L. A., 29 Apr 2014, In : British Journal of Cancer. 110, 9, p. 2246-2249 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Mutation analysis of aryl hydrocarbon receptor interacting protein (AIP) gene in colorectal, breast, and prostate cancers

Georgitsi, M., Karhu, A., Winqvist, R., Visakorpi, T., Waltering, K., Vahteristo, P., Launonen, V. & Aaltonen, L. A., 2007, In : British Journal of Cancer. 96, 2, p. 352-356 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer

Fang, H., Barbour, J. A., Poulos, R. C., Katainen, R., Aaltonen, L. A. & Wong, J. W. H., 3 Feb 2020, In : PLoS Genetics. 16, 2, 20 p., e1008572.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Multiple components of PKA and TGF-beta pathways are mutated in pseudomyxoma peritonei

Saarinen, L., Nummela, P., Thiel, A., Lehtonen, R., Järvinen, P., Järvinen, H., Aaltonen, L. A., Lepisto, A., Hautaniemi, S. & Ristimaki, A., 20 Apr 2017, In : PLoS One. 12, 4, 16 p., 0174898.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer

Tomlinson, I. P. M., Carvajal-Carmona, L. G., Dobbins, S. E., Tenesa, A., Jones, A. M., Howarth, K., Palles, C., Broderick, P., Jaeger, E. E. M., Farrington, S., Lewis, A., Prendergast, J. G. D., Pittman, A. M., Theodoratou, E., Olver, B., Walker, M., Penegar, S., Barclay, E., Whiffin, N., Martin, L. & 31 others, Ballereau, S., Lloyd, A., Gorman, M., Lubbe, S., Howie, B., Marchini, J., Ruiz-Ponte, C., Fernandez-Rozadilla, C., Castells, A., Carracedo, A., Castellvi-Bel, S., Duggan, D., Conti, D., Cazier, J-B., Campbell, H., Sieber, O., Lipton, L., Gibbs, P., Martin, N. G., Montgomery, G. W., Young, J., Baird, P. N., Gallinger, S., Newcomb, P., Hopper, J., Jenkins, M. A., Aaltonen, L. A., Kerr, D. J., Cheadle, J., Pharoah, P. & CORGI Collaborators, COGENT Consortium, EPICOLON Consortium, 2011, In : PLoS Genetics. 7, 6, p. e1002105 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Multiple clinical characteristics separate MED12-mutation-positive and -negative uterine leiomyomas

Heinonen, H-R., Pasanen, A., Heikinheimo, O., Tanskanen, T., Palin, K., Tolvanen, J., Vahteristo, P., Sjoberg, J., Pitkänen, E., Butzow, R., Makinen, N. & Aaltonen, L. A., 21 Apr 2017, In : Scientific Reports. 7, 7 p., 1015.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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MSH2 and MLH1 mutations in sporadic replication error-positive colorectal carcinoma as assessed by two-dimensional DNA electrophoresis

Wu, Y., Nyström-Lahti, M., Osinga, J., Looman, M. W. G., Peltomäki, P., Aaltonen, L. A., de la Chapelle, A., Hofstra, R. M. W. & Buys, C. H. C. M., 1997, In : Genes, Chromosomes & Cancer. 18, p. 269-278 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Molecular staging for survival prediction of colorectal cancer patients

Eschrich, S., Yang, I., Bloom, G., Kwong, K. Y., Boulware, D., Cantor, A., Coppola, D., Kruhøffer, M., Ørntoft, T. F., Quackenbush, J., Yeatman, T. J. & Aaltonen, L. A., 2005, In : Journal of Clinical Oncology. 23, 15, p. 3526-3535 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations

Georgitsi, M., Raitila, A., Karhu, A., Tuppurainen, K., Mäkinen, M. J., Vierimaa, O., Paschke, R., Saeger, W., van der Luijt, R. B., Sane, T., Robledo, M., de Menis, E., Weil, R. J., Wasik, A., Zielinski, G., Lucewicz, O., Lubinski, J., Launonen, V., Vahteristo, P. & Aaltonen, L. A., 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, p. 4101-4105 5 p.

Research output: Contribution to journalArticleScientificpeer-review