Lauri Kareinen — University of Helsinki

Phone+358504484300, +358294126529
Emaillauri.kareinenhelsinkifi

PL 21 (Haartmaninkatu 3)
00014
Finland
Finland

Research activity per year

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Fields of Science

413 Veterinary science

23 Article
1 Conference article

Complete Protection from SARS-CoV-2 Lung Infection in Mice Through Combined Intranasal Delivery of PIKfyve Kinase and TMPRSS2 Protease Inhibitors
Kant, R., Kareinen, L., Ojha, R., Strandin, T., Saber, S. H., Lesnikova, A., Kuivanen, S., Sironen, T., Joensuu, M., Vapalahti, O., Kirchhausen, T., Kipar, A. & Balistreri, G., 20 Jul 2023, In: bioRxiv.
Research output: Contribution to journal › Article › Scientific
Intranasal administration of adenoviral vaccines expressing SARS-CoV-2 spike protein improves vaccine immunity in mouse models
Freitag, T. L., Fagerlund, R., Karam, N. L., Leppänen, V-M., Ugurlu, H., Kant, R., Mäkinen, P., Tawfek, A., Kumar Jha, S., Strandin, T., Leskinen, K., Hepojoki, J., Kesti, T., Kareinen, L., Kuivanen, S., Koivulehto, E., Sormunen, A., Laidinen, S., Khattab, A., Saavalainen, P., & 7 othersMeri, S., Kipar, A., Sironen, T., Vapalahti, O., Alitalo, K., Ylä-Herttuala, S. & Saksela, K., 11 May 2023, In: Vaccine. 41, 20, p. 3233-3246 14 p.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
Intranasal trimeric sherpabody inhibits SARS-CoV-2 including recent immunoevasive Omicron subvariants
Mäkelä, A. R., Ugurlu, H., Hannula, L., Kant, R., Salminen, P., Fagerlund, R., Mäki, S., Haveri, A., Strandin, T., Kareinen, L., Hepojoki, J., Kuivanen, S., Levanov, L., Pasternack, A., Naves, R. A., Ritvos, O., Österlund, P., Sironen, T., Vapalahti, O., Kipar, A., & 3 othersHuiskonen, J. T., Rissanen, I. & Saksela, K., 24 Mar 2023, In: Nature Communications. 14, 1, 12 p., 1637.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
The infectivity of SARS-CoV-2 progeny virions requires the activity of host cell N-myristoyltransferases and it is severely compromised by their inhibition
Saber, H., Ojha, R. K., Quirin, T., Kant, R., Strandin, T., Kareinen, L., Yak, N., Sironen, T., Vapalahti, O., Balistreri, G. & Joensuu, M., 7 Mar 2023, In: bioRxiv.
Research output: Contribution to journal › Article › Scientific
Uncovering the implications of IFN-I in severe COVID-19 neutrophil inflammasome
Cabrera, L. E., Jokiranta, S. T., Mäki, S., Miettinen, S., Kant, R., Kareinen, L., Sironen, T., Pietilä, J-P., Kantele, A., Kekäläinen, E., Lindgren, H., Mattila, P., Kipar, A., Vapalahti, O. & Strandin, T., 2023, In: medRxiv.
Research output: Contribution to journal › Article › Scientific