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  • PL 63 (Haartmaninkatu 8)

    00014

    Finland

20042018
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Publications 2004 2018

2018

OSBP-related protein-2 (ORP2): a novel Akt effector that controls cellular energy metabolism

Kentala, H., Koponen, A., Vihinen, H., Pirhonen, J., Liebisch, G., Pataj, Z., Kivelä, A., Li, S., Karhinen, L., Jääskeläinen, E., Andrews, R., Meriläinen, L., Matysik, S., Ikonen, E., Zhou, Y., Jokitalo, E. & Olkkonen, V. M., Nov 2018, In : Cellular and Molecular Life Sciences. 75, 21, p. 4041-4057 17 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2017
Open Access
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2016

Identification of selective cytotoxic and synthetic lethal drug responses in triple negative breast cancer cells

Gautam, P., Karhinen, L., Szwajda, A., Jha, S. K., Yadav, B., Aittokallio, T. & Wennerberg, K., 10 May 2016, In : Molecular Cancer. 15, 16 p., 34.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Seipin regulates ER-lipid droplet contacts and cargo delivery

Salo, V. T., Belevich, I., Li, S., Karhinen, L., Vihinen, H., Vigouroux, C., Magre, J., Thiele, C., Hölttä-Vuori, M., Jokitalo, E. & Ikonen, E., 2016, In : EMBO Journal. 35, 24, p. 2699-2716 18 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2015

Systematic Mapping of Kinase Addiction Combinations in Breast Cancer Cells by Integrating Drug Sensitivity and Selectivity Profiles

Szwajda, A., Gautam, P., Karhinen, L., Jha, S. K., Saarela, J., Shakyawar, S., Turunen, L., Yadav, B., Tang, J., Wennerberg, K. & Aittokallio, T., 20 Aug 2015, In : Chemistry & Biology. 22, 8, p. 1144-1155 12 p.

Research output: Contribution to journalArticleScientificpeer-review

2013

Target Inhibition Networks: Predicting Selective Combinations of Druggable Targets to Block Cancer Survival Pathways

Tang, J., Karhinen, L., Xu, T., Szwajda, A., Yadav, B., Wennerberg, K. & Aittokallio, T., Sep 2013, In : PLoS Computational Biology. 9, 9, p. Article Number: e1003226 16 p.

Research output: Contribution to journalArticleScientificpeer-review

2009

Integrins mediate their unconventional, mechanical-stress-induced secretion via RhoA and PINCH in Drosophila

Schotman, H., Karhinen, L. & Rabouille, C., 2009, In : Journal of Cell Science. 122, p. 2662-2672 11 p.

Research output: Contribution to journalArticleScientificpeer-review

2008

dGRASP-mediated noncanonical integrin secretion is required for Drosophila epithelial remodeling

Schotman, H., Karhinen, L. & Rabouille, C., 2008, In : Developmental Cell. 14, p. 171-182 12 p.

Research output: Contribution to journalArticleScientificpeer-review

2005

Endoplasmic reticulum exit of a secretory glycoprotein in the absence of Sec24p family proteins in yeast

Karhinen, L., Nunes Bastos, R., Jokitalo, E. & Makarow, M., 2005, In : Traffic. 5, 7, p. 562-574 13 p.

Research output: Contribution to journalArticleScientificpeer-review

2004

Active and specific recruitment of a soluble cargo protein for endoplasmic reticulum exit in the absence of functional COPII component Sec24p

Fatal, N., Karhinen, L., Jokitalo, E. & Makarow, M., 2004, In : Journal of Cell Science. 117, p. 1665-1673 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Activity of recycling Golgi mannosyltransferases in the yeast endoplasmic reticulum

Karhinen, L. & Makarow, M., 2004, In : Journal of Cell Science. 117, p. 351-358 8 p.

Research output: Contribution to journalArticleScientificpeer-review