Research output per year
Research output per year
- 20 results
Search results
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2023
β2-integrins in Immunity: New Roles for Old Players
Uotila, L. & Harjunpää, H., 11 Mar 2023, Integrins in Health and Disease. Springer, p. 309-356 48 p. (Biology of Extracellular Matrix; vol. 13).Research output: Chapter in Book/Report/Conference proceeding › Chapter › Scientific › peer-review
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2019
A beta2-Integrin/MRTF-A/SRF Pathway Regulates Dendritic Cell Gene Expression, Adhesion, and Traction Force Generation
Guenther, C., Faisal, I., Uotila, L., Llort Asens, M., Harjunpää, H., Savinko, T., Öhman, T., Yao, S., Moser, M., Morris, S. W., Tojkander, S. & Fagerholm, S., 28 May 2019, In: Frontiers in Immunology. 10, 1138, 13 p., 1138.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Beta2-Integrins and Interacting Proteins in Leukocyte Trafficking, Immune Suppression, and Immunodeficiency Disease
Fagerholm, S. C., Guenther, C., Asens, M. L., Savinko, T. & Uotila, L. M., 19 Feb 2019, In: Frontiers in Immunology. 10, 10 p., 254.Research output: Contribution to journal › Review Article › peer-review
Open AccessFile -
2018
Filamin A Is Required for Optimal T Cell Integrin-Mediated Force Transmission, Flow Adhesion, and T Cell Trafficking
Savinko, T., Guenther, C., Uotila, L. M., Asens, M. L., Yao, S., Tojkander, S. & Fagerholm, S. C., 1 May 2018, In: Journal of Immunology. 200, 9, p. 3109-3116 8 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2017
Caveolin-1 Influences LFA-1 Redistribution upon TCR Stimulation in CD8 T Cells
Borger, J. G., Morrison, V. L., Filby, A., Garcia, C., Uotila, L. M., Simbari, F., Fagerholm, S. C. & Zamoyska, R., 1 Aug 2017, In: Journal of Immunology. 199, 3, p. 874-884 11 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Filamin A Regulates Neutrophil Adhesion, Production of Reactive Oxygen Species, and Neutrophil Extracellular Trap Release
Uotila, L. M., Günther, C., Savinko, T., Lehti, T. A. & Fagerholm, S. C., 15 Nov 2017, In: Journal of Immunology. 199, 10, p. 3644-3653 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2016
LFA-1 integrin antibodies inhibit leukocyte alpha(4)beta(1)-mediated adhesion by intracellular signaling
Grönholm, M., Jahan, F., Bryushkova, E. A., Madhavan, S., Aglialoro, F., Hinojosa, L. S., Uotila, L. M. & Gahmberg, C. G., 1 Sept 2016, In: Blood. 128, 9, p. 1270-1281 12 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Verisolujen integriinit ja taudit
Uotila, L., Savinko, T., Guenther, C. & Fagerholm, S., 2016, In: Duodecim. 132, 20, p. 1865-1873 9 p.Research output: Contribution to journal › Review Article › peer-review
Open AccessFile -
2015
Functional Beta2-Integrins Restrict Skin Inflammation In Vivo
Savinko, T. S., Morrison, V. L., Uotila, L. M., Wolff, C. H. J., Alenius, H. T. & Fagerholm, S. C., Sept 2015, In: Journal of Investigative Dermatology. 135, 9, p. 2249-2257 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Mice Lacking beta2-Integrin Function Remain Glucose Tolerant in Spite of Insulin Resistance, Neutrophil Infiltration and Inflammation
Meakin, P. J., Morrison, V. L., Sneddon, C. C., Savinko, T., Uotila, L., Jalicy, S. M., Gabriel, J. L., Kang, L., Ashford, M. L. J. & Fagerholm, S. C., 25 Sept 2015, In: PLoS One. 10, 9, 15 p., 0138872.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Optimal T Cell Activation and B Cell Antibody Responses In Vivo Require the Interaction between Leukocyte Function-Associated Antigen-1 and Kindlin-3
Morrison, V. L., Uotila, L. M., Llort Asens, M., Savinko, T. & Fagerholm, S. C., 1 Jul 2015, In: Journal of Immunology. 195, 1, p. 105-115 11 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2014
Regulation of integrin activity by phosphorylation.
Gahmberg, C. G., Grönholm, M. & Uotila, L., 2014, I domain integrins. Gullberg, D. (ed.). Springer, p. 85-96 12 p. (Advances in experimental medicine and biology; vol. 819).Research output: Chapter in Book/Report/Conference proceeding › Chapter › Scientific › peer-review
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Regulation of leukocyte integrin binding to Ig-family ligands
Uotila, L. M., Nov 2014, Helsinki. 78 p.Research output: Thesis › Doctoral Thesis › Collection of Articles
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Specific Phosphorylations Transmit Signals from Leukocyte beta(2) to beta(1) Integrins and Regulate Adhesion
Uotila, L. M., Jahan, F., Hinojosa, L. S., Melandri, E., Grönholm, M. & Gahmberg, C. G., 2014, In: Journal of Biological Chemistry. 289, 46, p. 32230-32242 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2013
Integrin CD11c/CD18 alpha-Chain Phosphorylation Is Functionally Important
Uotila, L. M., Aatonen, M. & Gahmberg, C. G., 2013, In: Journal of Biological Chemistry. 288, 46, p. 33494-33499 6 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Pilus Adhesin RrgA Interacts with Complement Receptor 3, Thereby Affecting Macrophage Function and Systemic Pneumococcal Disease
Orrskog, S., Rounioja, S., Spadafina, T., Gallotta, M., Norman, M., Hentrich, K., Fälker, S., Ygberg-Eriksson, S., Hasenberg, M., Johansson, B., Uotila, L. M., Gahmberg, C. G., Barocchi, M., Gunzer, M., Normark, S. & Henriques-Normark, B., 2013, In: mBio. 4, 1, 12 p., e00535.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Potato Crop as a Source of Emetic Bacillus cereus and Cereulide-Induced Mammalian Cell Toxicity
Hoornstra, D., Andersson, M. A., Teplova, V. V., Mikkola, R., Uotila, L. M., Andersson, L. C., Roivainen, M., Gahmberg, C. G. & Salkinoja-Salonen, M. S., 2013, In: Applied and Environmental Microbiology. 79, 12, p. 3534-3543 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2007
DC-SIGN binds ICAM-3 isolated from peripheral human leukocytes through Lewis x residues
Bogoevska, V., Nollau, P., Lucka, L., Grunow, D., Klampe, B., Uotila, L. M., Samsen, A., Gahmberg, C. G. & Wagener, C., 2007, In: Glycobiology. 17, 3, p. 324-333 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Red-cell ICAM-4 is a ligand for the monocyte/macrophage integrin CD11c/CD18: characterization of the binding sites on ICAM-4
Ihanus, E., Uotila, L. M., Toivanen, A., Varis, M. & Gahmberg, C. G., 2007, In: Blood. 109, 2, p. 802-810 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
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2003
Characterization of ICAM-4 binding to the I domains of the CD11a/CD18 and CD11b/CD18 leukocyte integrins
Ihanus, E., Uotila, L., Toivanen, A., Stefanidakis, M., Bailly, P., Cartron, J. P. & Gahmberg, C. G., 2003, In: European Journal of Biochemistry. 270, p. 1710-1723 14 p.Research output: Contribution to journal › Article › Scientific › peer-review