Liying Yu

Publications

Research output per year 2001 2001 2002 2003 2007 2008 2011 2012 2013 2017 2021 2022 2023 2023

• 13 Article
• 1 Meeting Abstract

Research output per year

Research output per year

Search results

• 2023

  MANF regulates neuronal survival and UPR through its ER-located receptor IRE1α

  Kovaleva, V., Yu, L.-Y., Ivanova, L., Shpironok, O., Nam, J., Eesmaa, A., Kumpula, E.-P., Sakson, S., Toots, U., Ustav, M., Huiskonen, J. T., Voutilainen, M. H., Lindholm, P., Karelson, M. & Saarma, M., 28 Feb 2023, In: Cell Reports. 42, 2, 31 p., 112066.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2022

  CDNF Interacts with ER Chaperones and Requires UPR Sensors to Promote Neuronal Survival

  Eesmaa, A., Yu, L.-Y., Göös, H., Danilova, T., Nöges, K., Pakarinen, E., Varjosalo, M., Lindahl, M., Lindholm, P. & Saarma, M., Aug 2022, In: International Journal of Molecular Sciences. 23, 16, 27 p., 9489.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access
• 2021

  The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor

  Eesmaa, A., Yu, L., Göös, H., Nõges, K., Kovaleva, V., Hellman, M., Zimmermann, R., Jung, M., Permi, P., Varjosalo, M., Lindholm, P. & Saarma, M., 2021, In: Journal of Biological Chemistry. 296, 23 p., 100295.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2017

  Zebrafish GDNF and its co-receptor GFR alpha 1 activate the human RET receptor and promote the survival of dopaminergic neurons in vitro

  Saarenpää, T., Kogan, K., Sidorova, Y., Mahato, A. K., Tascon, I., Kaljunen, H., Yu, L., Kallijärvi, J., Jurvansuu, J., Saarma, M. & Goldman, A., 3 May 2017, In: PLoS One. 12, 5, 18 p., 0176166.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2013

  Characterization of the Structural and Functional Determinants of MANF/CDNF in Drosophila In Vivo Model

  Lindström, R., Lindholm, P. K., Kallijärvi, J., Yu, L.-Y., Piepponen, T. P., Arumäe, U., Saarma, M. & Heino, T., 2013, In: PLoS One. 8, 9, 12 p., e73928.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• The Dependence Receptor TrkC Triggers Mitochondria-Dependent Apoptosis upon Cobra-1 Recruitment.

  Ichim, G., Genevois, A., Ménard , M., Yu, L.-Y., Coelho-Aguiar , J., Llambi , F., Jarrosson-Wuilleme , L., Lefebvre, J., Tulasne, D., Dupin , E., Le Douarin , N., Arumäe, U., Tauszig-Delamasure , S. & Mehlen, P., 2013, In: Molecular Cell. 51, 5, p. 632-646 15 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2012

  Characterization of the structural and functional determinants of MANF/CDNF proteins using Drosophila model

  Lindstrom, R., Lindholm, P., Yu, L.-Y., Kallijarvi, J., Arumae, U., Saarma, M. & Heino, T., Dec 2012, In: Journal of Neurogenetics. 26, p. 73-74 2 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

• 2011

  Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Has a Unique Mechanism to Rescue Apoptotic Neurons

  Hellman, M., Arumäe, U., Yu, L., Lindholm, P. K., Peränen, J., Saarma, M. & Permi, P., 2011, In: Journal of Biological Chemistry. 286, 4, p. 2675-2680 6 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2008

  Death receptors and caspases but not mitochondria are activated in the GDNF- or BDNF-deprived dopaminergic neurons

  Yu, L., Saarma, M. & Arumäe, U., 2008, In: Journal of Neuroscience. 28, 30, p. 7467-7475 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Survival assay of transiently transfected dopaminergic neurons

  Yu, L. & Arumäe, U., 2008, In: Journal of Neuroscience Methods. 169, 1, p. 8-15 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2007

  The TrkC receptor induces apoptosis when the dependence receptor notion meets the neurotrophin paradigm

  Tauszig-Delamasure, S., Yu, L., Cabrera, J. R., Bouzas-Rodriguez, J., Mermet-Bouvier, C., Guix, C., Arumäe, U. & Mehlen, P., 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 33, p. 13361-13366 6 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• 2003

  GDNF-deprived sympathetic neurons die via a novel nonmitochondrial pathway

  Yu, L. Y., Jokitalo, E., Sun, Y. F., Mehlen, P., Lindholm, D., Saarma, M. & Arumae, U., 2003, In: Journal of Cell Biology. 163, p. 987-997 11 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2002

  Neuronal apoptosis inhibitory protein: Structural requirements for hippocalcin binding and effects on survival of NGF-dependent sympathetic neurons

  Lindholm, D., Mercer, E. A., Yu, L., Chen, Y., Kukkonen, J., Korhonen, L. & Arumae, U., 2002, In: Biochimica et Biophysica Acta. Proteins and Proteomics. 1600, 1-2, p. 138-47 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2001

  Human glial cell line-derived neurotrophic factor receptor alpha 4 is the receptor for persephin and is predominantly expressed in normal and malignant thyroid medullary cells

  Lindahl, M., Poteryaev, D., Yu, L. Y., Arumae, U., Timmusk, T., Bongarzone, I., Aiello, A., Pierotti, M. A., Airaksinen, M. S. & Saarma, M., 2001, In: Journal of Biological Chemistry. 276, p. 9344-9351 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review