Research output per year
Research output per year
- 13 results
Search results
-
2023
MANF regulates neuronal survival and UPR through its ER-located receptor IRE1α
Kovaleva, V., Yu, L.-Y., Ivanova, L., Shpironok, O., Nam, J., Eesmaa, A., Kumpula, E.-P., Sakson, S., Toots, U., Ustav, M., Huiskonen, J. T., Voutilainen, M. H., Lindholm, P., Karelson, M. & Saarma, M., 28 Feb 2023, In: Cell Reports. 42, 2, 31 p., 112066.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2022
CDNF Interacts with ER Chaperones and Requires UPR Sensors to Promote Neuronal Survival
Eesmaa, A., Yu, L.-Y., Göös, H., Danilova, T., Nöges, K., Pakarinen, E., Varjosalo, M., Lindahl, M., Lindholm, P. & Saarma, M., Aug 2022, In: International Journal of Molecular Sciences. 23, 16, 27 p., 9489.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
2021
The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor
Yu, L., 2021, In: Journal of Biological Chemistry.Research output: Contribution to journal › Article › Scientific › peer-review
-
2017
Zebrafish GDNF and its co-receptor GFR alpha 1 activate the human RET receptor and promote the survival of dopaminergic neurons in vitro
Saarenpää, T., Kogan, K., Sidorova, Y., Mahato, A. K., Tascon, I., Kaljunen, H., Yu, L., Kallijärvi, J., Jurvansuu, J., Saarma, M. & Goldman, A., 3 May 2017, In: PLoS One. 12, 5, 18 p., 0176166.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2013
Characterization of the Structural and Functional Determinants of MANF/CDNF in Drosophila In Vivo Model
Lindström, R., Lindholm, P. K., Kallijärvi, J., Yu, L.-Y., Piepponen, T. P., Arumäe, U., Saarma, M. & Heino, T., 2013, In: PLoS One. 8, 9, 12 p., e73928.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
The Dependence Receptor TrkC Triggers Mitochondria-Dependent Apoptosis upon Cobra-1 Recruitment.
Ichim, G., Genevois, A., Ménard , M., Yu, L.-Y., Coelho-Aguiar , J., Llambi , F., Jarrosson-Wuilleme , L., Lefebvre, J., Tulasne, D., Dupin , E., Le Douarin , N., Arumäe, U., Tauszig-Delamasure , S. & Mehlen, P., 2013, In: Molecular Cell. 51, 5, p. 632-646 15 p.Research output: Contribution to journal › Article › Scientific › peer-review
-
2011
Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Has a Unique Mechanism to Rescue Apoptotic Neurons
Hellman, M., Arumäe, U., Yu, L., Lindholm, P. K., Peränen, J., Saarma, M. & Permi, P., 2011, In: Journal of Biological Chemistry. 286, 4, p. 2675-2680 6 p.Research output: Contribution to journal › Article › Scientific › peer-review
-
2008
Death receptors and caspases but not mitochondria are activated in the GDNF- or BDNF-deprived dopaminergic neurons
Yu, L., Saarma, M. & Arumäe, U., 2008, In: Journal of Neuroscience. 28, 30, p. 7467-7475 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
-
Survival assay of transiently transfected dopaminergic neurons
Yu, L. & Arumäe, U., 2008, In: Journal of Neuroscience Methods. 169, 1, p. 8-15 8 p.Research output: Contribution to journal › Article › Scientific › peer-review
-
2007
The TrkC receptor induces apoptosis when the dependence receptor notion meets the neurotrophin paradigm
Tauszig-Delamasure, S., Yu, L., Cabrera, J. R., Bouzas-Rodriguez, J., Mermet-Bouvier, C., Guix, C., Arumäe, U. & Mehlen, P., 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 33, p. 13361-13366 6 p.Research output: Contribution to journal › Article › Scientific › peer-review
-
2003
GDNF-deprived sympathetic neurons die via a novel nonmitochondrial pathway
Yu, L. Y., Jokitalo, E., Sun, Y. F., Mehlen, P., Lindholm, D., Saarma, M. & Arumae, U., 2003, In: Journal of Cell Biology. 163, p. 987-997 11 p.Research output: Contribution to journal › Article › Scientific › peer-review
-
2002
Neuronal apoptosis inhibitory protein: Structural requirements for hippocalcin binding and effects on survival of NGF-dependent sympathetic neurons
Lindholm, D., Mercer, E. A., Yu, L., Chen, Y., Kukkonen, J., Korhonen, L. & Arumae, U., 2002, In: Biochimica et Biophysica Acta. Proteins and Proteomics. 1600, 1-2, p. 138-47 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
-
2001
Human glial cell line-derived neurotrophic factor receptor alpha 4 is the receptor for persephin and is predominantly expressed in normal and malignant thyroid medullary cells
Lindahl, M., Poteryaev, D., Yu, L. Y., Arumae, U., Timmusk, T., Bongarzone, I., Aiello, A., Pierotti, M. A., Airaksinen, M. S. & Saarma, M., 2001, In: Journal of Biological Chemistry. 276, p. 9344-9351 8 p.Research output: Contribution to journal › Article › Scientific › peer-review