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Publications 2015 2019

  • 9 Article
  • 1 Meeting Abstract
  • 1 Doctoral Thesis
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Article
2019

Extracellular vesicles enhance the targeted delivery of immunogenic oncolytic adenovirus and paclitaxel in immunocompetent mice

Garofalo, M., Villa, A., Rizzi, N., Kuryk, L., Rinner, B., Cerullo, V., Yliperttula, M., Mazzaferro, V. & Ciana, P., 28 Jan 2019, In : Journal of Controlled Release. 294, p. 165-175 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Optimization of Early Steps in Oncolytic Adenovirus ONCOS-401 Production in T-175 and HYPERFlasks

Kuryk, L., Moller, A-S. W., Vuolanto, A., Pesonen, S., Garofalo, M., Cerullo, V. & Jaderberg, M., 1 Feb 2019, In : International Journal of Molecular Sciences. 20, 3, 15 p., 621.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2018

Antitumor effect of oncolytic virus and paclitaxel encapsulated in extracellular vesicles for lung cancer treatment

Garofalo, M., Saari, H., Somersalo, P., Crescenti, D., Kuryk, L., Aksela, L., Capasso, C., Madetoja, M., Koskinen, K., Oksanen, T., Mäkitie, A., Jalasvuori, M., Cerullo, V., Ciana, P. & Yliperttula, M., 1 Jun 2018, In : Journal of Controlled Release. 283, p. 223-234 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Antitumor-specific T-cell responses induced by oncolytic adenovirus ONCOS-102 (AdV5/3-D24-GM-CSF) in peritoneal mesothelioma mouse model

Kuryk, L., Moller, A-S. W., Garofalo, M., Cerullo, V., Pesonen, S., Alemany, R. & Jaderberg, M., Oct 2018, In : Journal of Medical Virology. 90, 10, p. 1669-1673 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2017

Toxicological and bio-distribution profile of a GM-CSF-expressing, double-targeted, chimeric oncolytic adenovirus ONCOS-102-Support for clinical studies on advanced cancer treatment

Kuryk, L., Vassilev, L., Ranki, T., Hemminki, A., Karioja-Kallio, A., Levälampi, O., Vuolanto, A., Cerullo, V. & Pesonen, S., 10 Aug 2017, In : PLoS One. 12, 8, 15 p., 0182715.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2016

Expression of DAI by an oncolytic vaccinia virus boosts the immunogenicity of the virus and enhances antitumor immunity

Hirvinen, M., Capasso, C., Guse, K., Garofalo, M., Vitale, A., Ahonen, M., Kuryk, L., Vähä-Koskela, M., Hemminki, A., Fortino, V., Greco, D. & Cerullo, V., 23 Mar 2016, In : Molecular Therapy - Oncolytics. 3, 9 p., 16002.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Oncolytic adenoviruses coated with MHC-I tumor epitopes increase the anti-tumor immunity and efficacy against melanoma

Capasso, C., Hirvinen, M., Garofalo, M., Romaniuk, D., Kuryk, L., Sarvela, T., Vitale, A., Antopolsky, M., Magarkar, A., Viitala, T., Suutari, T., Bunker, A., Yliperttula, M., Urtti, A. & Cerullo, V., 2016, In : OncoImmunology. 5, 4, 11 p., 1105429.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Oncolytic Adenovirus Loaded with L-carnosine as Novel Strategy to Enhance the Antitumor Activity

Garofalo, M., Iovine, B., Kuryk, L., Capasso, C., Hirvinen, M., Vitale, A., Yliperttula, M., Bevilacqua, M. A. & Cerullo, V., Apr 2016, In : Molecular Cancer Therapeutics. 15, 4, p. 651-660 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Synergistic anti-tumor efficacy of immunogenic adenovirus ONCOS-102 (Ad5/3-D24-GM-CSF) and standard of care chemotherapy in preclinical mesothelioma model

Kuryk, L., Haavisto, E., Garofalo, M., Capasso, C., Hirvinen, M., Pesonen, S., Ranki, T., Vassilev, L. & Cerullo, V., 15 Oct 2016, In : International Journal of Cancer. 139, 8, p. 1883-1893 11 p.

Research output: Contribution to journalArticleScientificpeer-review