Maciej Lalowski, Adjunct Professor

  • PL 63 (Haartmaninkatu 8)

    00014

    Finland

  • Viikinkaari 5, Biocenter 2

    00790 Helsinki

    Finland

19962020

Research output per year

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Personal profile

Research interests

Maciej Maurycy Lalowski works at the Medicum, Department of Biochemistry and Developmental Biology, Meilahti Clinical Proteomics Core Facility, HiLIFE, University of Helsinki. Maciej does research in Proteomics, Neurodegeneration and Mass Spectrometry Imaging. The current research projects relate to Alzheimer's Disease, Mood Disorders, Neuronal Ceroid Lipofuscinosis and Schizophrenia.

Education information

MSc degree (1991), graduated with distinction/Faculty of Biology, University of Warsaw, Poland, scope biochemistry

1991-1992: Postgraduate studies, graduated with distinction

Faculty of Geography, Institute of Developing Countries, University of Warsaw

PhD degree (1997), graduated with distinction

Polish Academy of Sciences, Warsaw-Poland /joint research at NYU Medical Center, Dept. of Pathology, NYC, USA (1992-1996)

Docent (2011): University of Helsinki, Faculty of Medicine, scope medical biochemistry

Education/Academic qualification

Alzheimer's Disease/aging, Doctor of Philosophy, Medical Research Center, Polish Academy of Sciences

1 Mar 19921 Dec 1997

Fields of Science

  • 3111 Biomedicine
  • Neurodegeneration
  • Mass spectrometry
  • Network biology
  • Proteomics
  • Bioinformatics, Systems biology
  • MALDI Imaging
  • Drug delivery
  • 1182 Biochemistry, cell and molecular biology
  • 3112 Neurosciences
  • 318 Medical biotechnology

International and National Collaboration Publications and projects within past five years.

Publications

Dynamic Interaction of USP14 with the Chaperone HSC70 Mediates Crosstalk between the Proteasome, ER Signaling, and Autophagy

Srinivasan, V., Bruelle, C., Scifo, E., Pham, D. D., Soliymani, R., Lalowski, M. & Lindholm, D. B., 24 Jan 2020, In : iScience. 23, 1, 33 p., 100790.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Epicardial transplantation of atrial appendage micrograft patch salvages myocardium after infarction

Xie, Y., Lampinen, M., Takala, J., Sikorski, V., Soliymani, R., Tarkia, M., Lalowski, M., Mervaala, E., Kupari, M., Zheng, Z., Hu, S., Harjula, A. & Kankuri, E., 7 Apr 2020, (Accepted/In press) In : Journal of Heart and Lung Transplantation. 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Inhibition of Activin/Myostatin signalling induces skeletal muscle hypertrophy but impairs mouse testicular development

Vaughan, D., Ritvos, O., Mitchell, R., Kretz, O., Lalowski, M., Amthor, H., Chambers, D., Matsakas, A., Pasternack, A., Collins-Hooper, H., Ballesteros, R., Huber, T. B., Denecke, B., Widera, D., Mukherjee, A. & Patel, K., 1 Apr 2020, In : European Journal of Translational Myology. 30, 1, p. 62-78 17 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Muscle NAD+ depletion and Serpina3n as molecular determinants of murine cancer cachexia – the effects of blocking myostatin and activins

Hulmi, J. J., Penna, F., Pöllänen, N. S., Nissinen, T. A., Hentila, J., Euro, L., Lautaoja, J. H., Ballarò, R., Soliymani, R., Baumann, M., Ritvos, O., Pirinen, E. & Lalowski, M., Jun 2020, (Accepted/In press) In : Molecular metabolism.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Proteomic and functional analyses in disease models reveal CLN5 protein involvement in mitochondrial dysfunction

Doccini, S., Morani, F., Nesti, C., Pezzini, F., Calza, G., Soliymani, R., Signore, G., Rocchiccioli, S., Kanninen, K. M., Huuskonen, M. T., Baumann, M., Simonati, A., Lalowski, M. & Santorelli, F. M., 30 Mar 2020, In : Cell death discovery . 6, 1, 14 p., 18.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Projects

Activities

Regulation of Pol II polymerase transcriptional reponse to DNA-damage by RBM7 and P-TEFb

Robert Fisher (Opponent), Maciej Lalowski (Other role (describe in more detail in "Relation description, notes" field)), Matjaz Barboric (Supervisor), Dan Bj Lindholm (Supervisor), Lea Sistonen (Pre-examiner), Minna Kaikkonen-Määttä (Pre-examiner)
22 Jan 2020

Activity: Examination typesPre-examiner of doctoral thesis

Federation of European Biochemical Societies (External organisation)

Maciej Lalowski (Board member)
1 Jan 202031 Dec 2024

Activity: Membership typesMembership or other role in public Finnish or international organization

Application of MALDI-mass spectrometry imaging for assessment of anti-neoplastic compounds in tissue.

Maciej Lalowski (Supervisor)
1 Mar 201930 Aug 2019

Activity: Examination typesSupervision of other thesis (Master's, Licentiate)

File

Serum proteomics to detect early changes in type 1 diabetes and carotid atherosclerosis

Maciej Lalowski (Pre-examiner), Tiina Öhman (Pre-examiner), Riitta Lahesmaa (Supervisor), Robert Moulder (Supervisor)
10 Oct 2018

Activity: Examination typesPre-examiner of doctoral thesis

Functional omics approaches towards affected molecular pathways underlying various forms of Neuronal Ceroid Lipofuscinoses

Maciej Lalowski (Pre-examiner), Katja Kanninen (Pre-examiner), Pasquale Striano (Pre-examiner), Filippo M. Santorelli (Supervisor), Giovanni Cionni (Supervisor)
Feb 2018

Activity: Examination typesPre-examiner of doctoral thesis

Press / Media

A potential treatment for cardiac regeneration

Maciej Lalowski

30/06/2020

3 items of Media coverage

Press/Media: Press / Media

Researchers have found a promising therapy for cardiac regeneration

Maciej Lalowski

30/06/2020

5 items of Media coverage

Press/Media: Press / Media

'Multiomics' and the newborn mouse heart

Maciej Lalowski

01/06/201804/06/2018

3 items of Media coverage

Press/Media: Press / Media

Researchers use 'multiomics' approach to study newborn mouse heart

Maciej Lalowski

04/06/2018

1 item of Media coverage

Press/Media: Press / Media